Canisius vs Siena Prediction, Picks & Odds | 07 Dec 2025

College Basketball Betting Preview: Canisius vs Siena

The Canisius Golden Griffins go up against the Siena Saints, with tip-off scheduled for 14:00 on Sunday, December 7.

There’s a case to be made for Siena on the spread when they face Canisius. Our prediction is that the betting favorites can cover the -16.5 line at odds of -112 considering they should be superior.

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Canisius Golden Griffins lost on the road in their previous game. Saint Peter's Peacocks won 69-57.

Siena Saints won their last game which was at home. It was a 83-54 triumph against Niagara Purple Eagles.

Head-to-Head Statistics

Canisius had the edge in the most recent matchup between these teams. They recorded a 93-88 win over Siena. Canisius have won six of the previous 10 H2H meetings.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Siena	8-2	701	623	78	3-1	5-1	6W
Canisius	4-5	555	631	-76	4-1	0-4	2L

View Full Standings

Canisius vs Siena Prediction & Picks

Gear up for Canisius vs Siena with our betting guide, featuring an expert match prediction, scoreline advice and a hand-picked bet builder. Explore each section below for detailed insights.

Game Prediction

Siena can enjoy a huge victory in this college matchup and a wager on the spread could be the best way forward. Back the big favorites off -16.5 to cover the line at -112.

Sportsgambler.com brings strong college hoops expertise, built on knowing the team news as soon as it’s confirmed. Recent form plays a big part in our basketball picks and we always back it up with the most relevant stats.

Key Canisius vs Siena stats:

• The +16.5 line hasn’t been covered by Canisius in 12 of their last 20 games on the road.
• The +16.5 line hasn’t been covered by Canisius in 3 of their last 5 games on the road.

Siena -16.5 Probability

According to the latest odds, our pick has a 52.9% chance of delivering a return. However, our analysts have this number between 55-60% based on their in-depth research. This is why we can recommend this college basketball wager.

If you want to secure a bigger possible payout on your bet, there’s the option to move the line. Take a look at the various prices and see which line you think will be covered.

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Our Game Prediction

Siena -16.5 @ -112 Bet Now

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Correct Score Prediction

Canisius 58 - 77 Siena

If you want to achieve a big return from your stake, then it’s worth checking out the correct score lines. Siena to claim a 77-58 victory is on offer at huge betting odds.

Canisius vs Siena Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Siena are massive favorites for this college game, with some sportsbooks not even offering Moneyline wagering. Therefore, they’re available on the spread depending on what you expect the winning margin to be.

16.5 is where the spread lies, with total points being 128.5 right now. Basketball bettors love the chance to get an alternative angle by going for a Total wager. If you want to wager Over 128.5, there are odds of -112.

College basketball fans are spoiled for choice with the wide range of team props and game lines available for every matchup on the schedule. Visit the top sportsbooks to find the best value picks.

Moneyline

Canisius

-

Siena

-

Point Spread

Canisius +16.5

-105

Siena -16.5

-115

Total Points

Under 128.5

-108

Over 128.5

-112

As an alternative to the game lines and team props, check out the player props that are available. These can be a great alternative if you want to focus on a player’s performance. The best gambling sites will provide lots of options.

An increasing number of bettors are now enjoying micro betting on college basketball and it’s something which is available on an in-game basis. Wait for the action to start and then wager on something specific to happen.

Latest regular season and playoff games stats.

Canisius Stats

Siena Stats

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 1 win and 9 defeats in the last 10 games on the road

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +16.5 Betting Line: Have covered the spread in 6 of the last 10 games
• +16.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• -16.5 Betting Line: Have covered the spread in 1 of the last 10 games
• -16.5 Betting Line at Home: Have covered the spread in 2 of the last 10 home games

Total Points

• Game Totals: An average of 131.80 pts in the previous 10 games
• Game Totals on the Road: An average of 142.60 pts in the previous 10 games on the road
• Over 130.5: Covered in 5 of the previous 10 games
• Over 130.5 on the Road: Covered in 7 of the previous 10 games on the road
• Team Totals: Have scored an average of 61.70 pts and allowed 70.10 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 62.20 pts and allowed 80.40 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 132.40 pts in the previous 10 games
• Game Totals at Home: An average of 145.70 pts in the previous 10 home games
• Over 130.5: Covered in 7 of the previous 10 games
• Over 130.5 at Home: Covered in 9 of the previous 10 home games
• Team Totals: Have scored an average of 70.10 pts and allowed 62.30 pts in the last 10 games
• Team Totals at Home: Have scored an average of 78.20 pts and allowed 67.50 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Metro Atlantic Athletic	Overall	PF	PA	N. Pts	Home	Away	Strk
Siena	8-2	701	623	78	3-1	5-1	6W
Marist	5-2	502	415	87	4-1	1-1	3W
Quinnipiac	6-3	726	677	49	3-1	3-2	2W
Iona	6-3	749	719	30	3-2	3-1	1L
Fairfield	5-4	671	691	-20	3-1	2-3	1L
Manhattan	4-5	740	766	-26	3-1	1-4	1W
Canisius	4-5	555	631	-76	4-1	0-4	2L
Saint Peter's	3-4	472	529	-57	3-1	0-3	1W
Merrimack	4-6	650	751	-101	2-1	2-5	2W
Sacred Heart	3-5	638	657	-19	2-0	1-5	1W
Niagara	2-6	498	606	-108	1-1	1-5	5L
Mount St. Mary's	2-8	670	798	-128	1-2	1-6	2L
Rider	1-6	433	548	-115	1-1	0-5	4L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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