La Salle vs Penn Prediction, Picks & Odds | 29 Nov 2025

College Basketball Betting Preview: La Salle vs Penn

The La Salle Explorers face the Penn Quakers, with tip-off scheduled for 16:30 on Saturday, November 29.

We expect Penn to cover the -3.5 line on the spread. This is a really good number and that’s why we’re playing the favorites at -110 to overcome La Salle.

Rolling with our spread angle? Read our BetMGM sportsbook review, then access the best promo code before placing your bet.

La Salle Explorers lost when they last took to the court. They were turned over 63-58 at home to Hofstra Pride.

Penn Quakers won their last game, beating Merrimack Warriors at home. It was a 77-65 win.

Head-to-Head Statistics

The last head-to-head saw La Salle claim a 93-92 (OT) win over Penn. La Salle have three straight victories against Penn. They have won 3 of the 5 previous head-to-head matchups.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Penn	4-2	522	469	53	3-0	1-2	3W
La Salle	3-4	480	471	9	3-2	0-2	1L

View Full Standings

La Salle vs Penn Prediction & Picks

The La Salle vs Penn betting tips feature sharp analysis across major markets, including a key match prediction, correct score guidance and a ready-made bet builder.

Game Prediction

Penn really stand out in this college contest. Back them at -3.5 on the spread with the confidence that the betting favorites cover the line at -110.

Tracking injury updates is a big part of our college hoops analysis and team news plays a major role in shaping our basketball picks. We combine this with recent form and the most important stats to get a complete picture.

Key La Salle vs Penn stats:

• The -3.5 line has been covered by Penn in 4 of their last 5 games at home.
• The -3.5 line has been covered by Penn in 3 consecutive games.
• The +3.5 line hasn’t been covered by La Salle in 9 of their last 10 games on the road.
• The +3.5 line hasn’t been covered by La Salle in 4 of their last 5 games.
• The +3.5 line hasn’t been covered by La Salle in 3 consecutive games on the road.

Penn -3.5 Probability

According to the best betting apps, our pick has a 52.4% chance of delivering a return. However, we think that the probability sits between 55-60% taking all factors into consideration. This college basketball wager can therefore be backed with confidence.

There are several alternatives to the spread and we particularly like the Winning Margin lines. It’s great whether you’re expecting things to be close or comprehensive.

Thinking about placing a wager? Explore our updated guide filled with top betting offers, free bets, and promotions.

Our Game Prediction

Penn -3.5 @ -110 Bet Now

BetMGM Promo Up To $1500 in Bonus Bets Get Bonus T&C apply. Gamble responsibly 18+

Gamble responsibly 18+. All odds are correct at time of publishing and are subject to change. To use the Bookmaker Live Streaming services you will need to be logged in and have a funded account or to have placed a bet in the last 24 hours. Geo-restrictions apply.

Correct Score Prediction

La Salle 75 - 82 Penn

A 82-75 win for the Quakers is clearly a risky bet although this could be an exciting correct score option where there’s the chance to enjoy a huge potential return.

La Salle vs Penn Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

The Penn odds have been priced up by the sportsbooks and they are -200 betting favorites to land victory in this college game which means a 67% chance of winning. If you’re looking for an alternative angle, La Salle are trading at +164.

The spread currently stands at 3.5 and the total points line is 149.5. Having a wager on the Totals is one of the most popular basketball bets. If you want to back Over 149.5, it’s -115.

There are plenty of team props and game lines available for college basketball wagering, and we recommend checking out the top sportsbooks to find the bet that aligns with your prediction for the game.

Moneyline

La Salle

+164

Penn

-200

Point Spread

La Salle +3.5

-102

Penn -3.5

-120

Total Points

Under 149.5

-105

Over 149.5

-115

Prop betting is very popular, with bettors looking to wager on player props such as Points, Assists, Rebounds, Steals and Three-Pointers. It’s a great way of betting on individual player performance and the gambling sites will provide lots of options.

There are always opportunities to enjoy college basketball micro betting. It’s generally the case that you will find player and team props in-game and bettors can use their insight to wager on outcomes such as if the next shot will be a Two or Three-Pointer.

Latest regular season and playoff games stats.

La Salle Stats

Penn Stats

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 1 win and 9 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 home games

Point Spread

• +3.5 Betting Line: Have covered the spread in 5 of the last 10 games
• +3.5 Betting Line on the Road: Have covered the spread in 1 of the last 10 games on the road

Point Spread

• -3.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -3.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games

Total Points

• Game Totals: An average of 140.00 pts in the previous 10 games
• Game Totals on the Road: An average of 143.40 pts in the previous 10 games on the road
• Over 150.5: Covered in 3 of the previous 10 games
• Over 150.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 70.90 pts and allowed 69.10 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 65.40 pts and allowed 78.00 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 164.50 pts in the previous 10 games
• Game Totals at Home: An average of 158.10 pts in the previous 10 home games
• Over 150.5: Covered in 9 of the previous 10 games
• Over 150.5 at Home: Covered in 8 of the previous 10 home games
• Team Totals: Have scored an average of 82.50 pts and allowed 82.00 pts in the last 10 games
• Team Totals at Home: Have scored an average of 81.30 pts and allowed 76.80 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Ivy League	Overall	PF	PA	N. Pts	Home	Away	Strk
Yale	6-1	601	517	84	2-1	4-0	3W
Columbia	6-1	556	477	79	3-0	3-1	5W
Cornell	4-2	559	501	58	3-0	1-2	4W
Penn	4-2	522	469	53	3-0	1-2	3W
Harvard	4-4	570	540	30	2-1	2-3	3L
Brown	3-5	525	542	-17	1-3	2-2	2W
Princeton	3-6	651	694	-43	3-2	0-4	3L
Dartmouth	1-3	321	310	11	1-2	0-1	1W

Atlantic 10	Overall	PF	PA	N. Pts	Home	Away	Strk
George Mason	7-0	558	433	125	5-0	2-0	7W
George Washington	7-1	737	595	142	6-0	1-1	1L
Saint Louis	6-1	626	491	135	6-1	0-0	1L
Richmond	6-1	593	474	119	5-0	1-1	1W
Davidson	6-1	544	491	53	4-1	2-0	1W
St. Bonaventure	6-1	529	483	46	5-0	1-1	1W
Rhode Island	6-2	629	541	88	3-1	3-1	2W
Dayton	6-2	632	563	69	5-1	1-1	1L
Fordham	5-2	540	433	107	5-1	0-1	3W
Duquesne	5-2	618	562	56	5-1	0-1	1W
VCU	5-3	676	581	95	4-1	1-2	1W
Saint Joseph's	3-3	479	478	1	3-0	0-3	1W
La Salle	3-4	480	471	9	3-2	0-2	1L
Loyola Chicago	1-7	520	611	-91	1-5	0-2	7L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

Top Basketball Pages