Chicago State vs DePaul Prediction, Picks & Odds | 03 Nov 2025

College Basketball Betting Preview: Chicago State vs DePaul

The Chicago State Cougars square off against the DePaul Blue Demons, with tip-off scheduled for 20:00 on Monday, November 3. Our betting preview features expert NCAAB predictions, betting tips, the latest odds and H2H stats.

We’re Backing CSU to Cover the Line

Chicago State have been given a sizeable +24.5 on the spread and we’re looking to take advantage. Back the -112 that the underdogs avoid a big loss against DePaul.

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DePaul 70-58 Winners in Most Recent H2H

Chicago State Cougars suffered a defeat in their previous game. A 68-57 scoreline occurred on the road against LIU Sharks.

DePaul Blue Demons lost 83-61 to Cincinnati Bearcats when they last took to the court.

Head-to-Head Statistics

It was a 70-58 win for DePaul when they last played Chicago State.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
DePaul	0-0	0	0	0	0-0	0-0	-
Chicago State	0-0	0	0	0	0-0	0-0	-

View Full Standings

Chicago State vs DePaul Prediction & Picks

Gear up for Chicago State vs DePaul with our betting guide, featuring an expert match prediction, scoreline advice and a hand-picked bet builder. Explore each section below for detailed insights.

Game Prediction

Let’s back the underdogs at +24.5 to outrun their odds on the spread. Chicago State are a good shout at -112 to stay relatively close to their opponents in this college contest.

Recent form is always part of the equation and we combine it with team news as soon as it’s available. To deliver expert basketball predictions, our handicappers also analyze the latest college hoops stats to ensure we’re working with the best information possible.

Key Chicago State vs DePaul stats:

• The +24.5 line has been covered by CSU in 6 consecutive games.
• The +24.5 line has been covered by CSU in 9 of their last 10 games.
• The +24.5 line has been covered by CSU in 18 of their last 20 games.
• The -24.5 line hasn’t been covered by DePaul in 20 consecutive games.

CSU +24.5 Probability

Based on the odds from the top betting sites, there’s a 52.9% likelihood of our pick delivering a return. Based on our in-depth research, we calculate the actual probability to be 55-60%. It’s the reason why we are recommending this college basketball bet.

If the initial odds don’t grab your fancy, there’s the option to shoot for more juice by moving the line when it comes to your pick. It all comes down to how confident you feel.

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Best Bet

Chicago State +24.5 @ -112 Bet Now

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Correct Score Prediction

Chicago State 63 - 85 DePaul

Should you wish to go for a speculative bet, try the Blue Demons to win 85-63 on the correct score lines. This should be a fun wager which could potentially yield a huge return.

Chicago State vs DePaul Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Books Expecting a Landslide Win for DePaul

DePaul are massive favorites for this college game, with some sportsbooks not even offering Moneyline wagering. Therefore, they’re available on the spread depending on what you expect the winning margin to be.

There is a spread of 24.5 and total points has a line of 143.5. The advantage of the Totals is that you only have to choose from one of two options. If you're keen on Over 143.5, this selection is available at -110.

If you’re planning to place a bet on a college hoops matchup, visit the top basketball betting sites and check out the many available game lines and team props. Find the lines which are the most attractive.

Moneyline

CSU

-

DePaul

-

Point Spread

CSU +24.5

-105

DePaul -24.5

-115

Total Points

Under 143.5

-110

Over 143.5

-110

Player Props & Micro Betting

As an alternative to the game lines, check out the player prop bets that are available. It’s especially great if you have a view when it comes to Turnovers, Steals, Blocks and Points, while there are lots of other options.

Micro betting is an exciting way to wager on college basketball. There are many live lines and it’s a simple case of predicting what is going to happen. Next Field Goal, where you select if the shot will be a two or three-pointer are among the options.

Last 5 & H2H

Latest regular season and playoff games stats.

Chicago State Stats

DePaul Stats

Moneyline

• 2 wins and 8 defeats in the last 10 games
• 1 win and 9 defeats in the last 10 games on the road

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 home games

Point Spread

• +24.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +24.5 Betting Line on the Road: Have covered the spread in 8 of the last 10 games on the road

Point Spread

• -24.5 Betting Line: Have not covered the spread in any of the last 10 games
• -24.5 Betting Line at Home: Have not covered the spread in any of the last 10 home games

Total Points

• Game Totals: An average of 145.40 pts in the previous 10 games
• Game Totals on the Road: An average of 141.10 pts in the previous 10 games on the road
• Over 143.5: Covered in 6 of the previous 10 games
• Over 143.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 67.40 pts and allowed 78.00 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 62.40 pts and allowed 78.70 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 148.00 pts in the previous 10 games
• Game Totals at Home: An average of 142.30 pts in the previous 10 home games
• Over 143.5: Covered in 6 of the previous 10 games
• Over 143.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 69.70 pts and allowed 78.30 pts in the last 10 games
• Team Totals at Home: Have scored an average of 68.30 pts and allowed 74.00 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big East	Overall	PF	PA	N. Pts	Home	Away	Strk
Butler	0-0	0	0	0	0-0	0-0	-
UConn	0-0	0	0	0	0-0	0-0	-
Creighton	0-0	0	0	0	0-0	0-0	-
DePaul	0-0	0	0	0	0-0	0-0	-
Georgetown	0-0	0	0	0	0-0	0-0	-
Marquette	0-0	0	0	0	0-0	0-0	-
St. John's	0-0	0	0	0	0-0	0-0	-
Villanova	0-0	0	0	0	0-0	0-0	-
Xavier	0-0	0	0	0	0-0	0-0	-

Northeast	Overall	PF	PA	N. Pts	Home	Away	Strk
Central Conn. St.	0-0	0	0	0	0-0	0-0	-
Chicago State	0-0	0	0	0	0-0	0-0	-
Fairleigh Dickinson	0-0	0	0	0	0-0	0-0	-
LIU	0-0	0	0	0	0-0	0-0	-
Le Moyne	0-0	0	0	0	0-0	0-0	-
Mercyhurst	0-0	0	0	0	0-0	0-0	-
St. Francis (PA)	0-0	0	0	0	0-0	0-0	-
Stonehill	0-0	0	0	0	0-0	0-0	-
Wagner	0-0	0	0	0	0-0	0-0	-

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak