Southern Miss vs South Carolina Prediction, Picks & Odds | 09 Nov 2025

College Basketball Betting Preview: Southern Miss vs South Carolina

The Southern Miss Golden Eagles square off against the South Carolina Gamecocks, with tip-off scheduled for 18:30 on Sunday, November 9. Our betting preview features expert NCAAB predictions, betting tips, the latest odds and H2H stats.

Big Line Looks Juicy for the Underdogs

We’re expecting Southern Miss to keep the scoreline respectable and the spread of +18.5 looks generous at odds of -106 when they play South Carolina.

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Both Teams Won Last Time Out

Southern Miss Golden Eagles won their previous game, beating Tougaloo Bulldogs at home. It was a 93-57 win.

South Carolina Gamecocks last game saw them claim a 91-72 home win over North Carolina A&T Aggies.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
South Carolina	1-0	91	72	19	1-0	0-0	1W
Southern Miss	1-1	172	142	30	1-0	0-1	1W

View Full Standings

Southern Miss vs South Carolina Prediction & Picks

This Southern Miss vs South Carolina betting guide features sharp analysis across major markets, including an expert match prediction, correct score bet and a strategic bet builder.

Game Prediction

The best bet could be Southern Miss at -106 on the spread. They have been given a +18.5 points start and should be able to stay relatively close to the big favorites in this college matchup.

The college hoops handicappers at Sportsgambler.com start by analyzing recent form and staying on top of injury news before making any basketball picks. From there, we interpret the story the stats are telling to help shape our predictions.

Key Southern Miss vs South Carolina stats:

• The +18.5 line has been covered by Southern Miss in 9 consecutive games.
• The +18.5 line has been covered by Southern Miss in 19 of their last 20 games.
• The -18.5 line hasn’t been covered by South Carolina in 18 of their last 20 games.
• The -18.5 line hasn’t been covered by South Carolina in 8 of their last 10 games.

Southern Miss +18.5 Probability

According to the top betting apps, there’s a 51.5% likelihood of our pick delivering a return. Based on our in-depth research, we calculate the actual probability to be closer to 60%. It’s why we think it’s worth placing this college basketball bet.

There’s the chance to sell points and that means moving the line until you’re happy with the wager. It means a riskier bet but a bigger return on the odds available.

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Best Bet

Southern Miss +18.5 @ -106 Bet Now

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Correct Score Prediction

Southern Miss 66 - 81 South Carolina

Should you wish to go for a speculative bet, try South Carolina to win 81-66 on the correct score lines. This should be a fun wager which could potentially yield a huge return.

Southern Miss vs South Carolina Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Books Have South Carolina as Heavy Favorites

The favorites are 98% likely to win according to the sportsbooks’ latest Moneyline odds, with South Carolina priced at -5000 to triumph in this college game. Southern Miss are regarded as a long shot to win and you can currently back them at +1400.

The spread is currently 18.5, with the total points line at 150.5. A bet on the Totals allows fans to use the latest basketball data to good effect. There’s the chance to back Under 150.5 at -105.

Consider every angle when placing your college hoops bets. The top basketball betting sites offer a huge selection of game lines and team props, and it’s all about finding a wager that fits your prediction of the game.

Moneyline

Southern Miss

+1400

South Carolina

-5000

Point Spread

Southern Miss +18.5

-106

South Carolina -18.5

-114

Total Points

Under 150.5

-105

Over 150.5

-115

Player Props & Micro Betting

As an alternative to the game lines, check out the player prop bets that are available. It’s especially great if you have a view when it comes to Turnovers, Steals, Blocks and Points, while there are lots of other options.

Among the various options for wagering on college basketball, you will find that micro betting is provided. It focuses on short-term in-game outcomes such as Next Field Goal, where you select if the shot will be a two or three-pointer.

Last 5 & H2H

Latest regular season and playoff games stats.

Southern Miss Stats

South Carolina Stats

Moneyline

• 2 wins and 8 defeats in the last 10 games
• 1 win and 9 defeats in the last 10 games on the road

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 home games

Point Spread

• +18.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +18.5 Betting Line on the Road: Have covered the spread in 9 of the last 10 games on the road

Point Spread

• -18.5 Betting Line: Have covered the spread in 2 of the last 10 games
• -18.5 Betting Line at Home: Have covered the spread in 2 of the last 10 home games

Total Points

• Game Totals: An average of 149.30 pts in the previous 10 games
• Game Totals on the Road: An average of 146.10 pts in the previous 10 games on the road
• Over 150.5: Covered in 5 of the previous 10 games
• Over 150.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 72.10 pts and allowed 77.20 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 69.00 pts and allowed 77.10 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 147.30 pts in the previous 10 games
• Game Totals at Home: An average of 141.50 pts in the previous 10 home games
• Over 150.5: Covered in 4 of the previous 10 games
• Over 150.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 71.70 pts and allowed 75.60 pts in the last 10 games
• Team Totals at Home: Have scored an average of 71.10 pts and allowed 70.40 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Southeastern	Overall	PF	PA	N. Pts	Home	Away	Strk
Georgia	2-0	198	88	110	2-0	0-0	2W
Kentucky	2-0	184	110	74	2-0	0-0	2W
Texas A&M	2-0	202	138	64	2-0	0-0	2W
Vanderbilt	2-0	210	154	56	1-0	1-0	2W
Tennessee	2-0	171	117	54	2-0	0-0	2W
Ole Miss	2-0	174	123	51	2-0	0-0	2W
Auburn	2-0	190	147	43	2-0	0-0	2W
Alabama	2-0	194	158	36	1-0	1-0	2W
LSU	1-0	96	60	36	1-0	0-0	1W
Missouri	2-0	177	151	26	1-0	1-0	2W
Mississippi State	1-0	86	62	24	1-0	0-0	1W
South Carolina	1-0	91	72	19	1-0	0-0	1W
Florida	1-1	191	157	34	1-0	0-1	1W
Arkansas	1-1	175	146	29	1-0	0-1	1L
Texas	1-1	157	135	22	1-0	0-1	1W
Oklahoma	1-1	170	149	21	1-0	0-1	1L

Sun Belt	Overall	PF	PA	N. Pts	Home	Away	Strk
South Alabama	3-0	251	194	57	2-0	1-0	3W
Marshall	2-0	163	145	18	0-0	2-0	2W
Troy	2-0	167	158	9	0-0	2-0	2W
Coastal Carolina	1-1	192	120	72	1-0	0-1	1W
Appalachian State	1-1	158	128	30	1-0	0-1	1W
Southern Miss	1-1	172	142	30	1-0	0-1	1W
Old Dominion	1-1	165	140	25	1-0	0-1	1W
Georgia Southern	1-1	182	182	0	1-0	0-1	1W
James Madison	1-1	141	141	0	1-0	0-1	1W
Louisiana	1-1	122	127	-5	1-0	0-1	1W
Arkansas State	1-1	154	175	-21	0-0	1-1	1L
Texas State	1-2	233	217	16	1-0	0-2	1L
Georgia State	0-2	113	145	-32	0-0	0-2	2L
UL Monroe	0-2	147	188	-41	0-0	0-2	2L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak