América de Cali vs Fluminense Prediction, Betting Tips, Lineups & Odds | 12 Aug 2025

Copa Sudamericana Betting Preview: América de Cali vs Fluminense

Colombian Categoria Primera A outfit América de Cali host Brazilian Série A side Fluminense in the first leg of this Copa Sudamericana round of 16 tie at Estadio Pascual Guerrero, with kick-off set for 20:30 on Tuesday 12 August. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats and team news.

Big Flu Should Compete Favourably

Fluminense look a nice wager to topple América de Cali and we can take them at -179 with a +0.25 goal headstart on the Asian Handicap. This means dividing our stake equally between 0 and +0.5 in the hope of a payout.

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América Bidding to Bounce Back After Loss

América de Cali fell to a 1-0 home defeat against Deportes Tolima in their most recent outing. Los Diablos Rojos enjoyed 57% possession but managed just one shot on target in a frustrating Primera A performance.

Fluminense drew 3-3 in their previous game. This took place on their travels against Bahia in Série A. The Big Flu had 40% possession and five shots on goal, while German Cano was on the scoresheet twice and Nonato also found the net.

Copa Sudamericana		G	W	D	L	GF	GA	GD	GD	P
2	América de Cali	6	1	5	0	6	4	2	6:4	8
1	Fluminense	6	4	1	1	11	2	9	11:2	13

View Full Table

Confirmed Lineups

América de Cali confirmed lineup (4-2-3-1): Jorge Soto (GK), Cristian Tovar, Jean Pestana, Yerson Candelo, Marcos Mina, Josen Escobar, Rafael Carrascal, Cristian Barrios, Sebastian Navarro, Jan Franc Lucumi, Luis Ramos.

Fluminense confirmed lineup (4-3-3): Fabio (GK), Samuel Xavier, Manoel Messias, Juan Freytes, Rene, Martinelli, Hercules, Vinicius Lima, Agustin Canobbio, Everaldo, Kevin Serna.

América de Cali vs Fluminense Prediction & Betting Tips

The América de Cali vs Fluminense betting tips feature sharp analysis across major markets, including a key match prediction, player prop bets, correct score guidance and a ready-made bet builder.

Match Prediction

We’re siding with Fluminense at -179 in this Copa Sudamericana match with a +0.25 goal advantage. It’s expected that they will have an edge and we can therefore feel bullish of a return with this wager.

Our job is to consult the latest Copa Sudamericana team news in order to produce the best football predictions. Then we crack on with the job of analysing the stats that are going to be the most effective.

Key América de Cali vs Fluminense Copa Sudamericana & league stats:

• The +0.25 line has been covered by Fluminense in 13 of their last 20 games.
• The +0.25 line has been covered by Fluminense in 6 of their last 10 games.
• The +0.25 line has been covered by Fluminense in 2 consecutive games.
• The -0.25 line hasn’t been covered by América in 7 of their last 10 games.
• The -0.25 line hasn’t been covered by América in 12 of their last 20 games.
• The -0.25 line hasn’t been covered by América in 2 consecutive games.

Fluminense +0.25 Probability

Based on the odds from the best betting apps, our pick carries a 64.1% chance of winning. However, our experts think that the probability is close to 70% taking all factors into consideration. This is why we can recommend this wager.

Lots of bettors wanting to back Fluminense to cover the line will look to combine this pick in a Bet Builder. This provides you with the opportunity to secure a bigger price by featuring a number of selections.

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Our Match Prediction

Fluminense Asian Hcp +0.25 @ -179 Bet Now

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Correct Score Prediction

América 0 - 1 Fluminense

We’re going for Fluminense at +650 to secure a 1-0 win. It’s exciting to bet on the correct score and this wager will hopefully be able to land a nice return.

Player Prop Picks

Top Pick: Kevin Serna to Score +650

Kevin Serna (Fluminense) has racked up two goals in his past nine matches. We think this is the pick of the player props, with a generous +650 available when it comes to backing him to score at any time.

Latest Kevin Serna Player Prop Odds

Goalscorer

Anytime

+1100

First

+1900

Shots

Over 0.5

-192

Under 0.5

-

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América de Cali vs Fluminense Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Latest Match Odds Suggest a Close-Run Battle

For this Copa Sudamericana encounter, the bookmakers have América de Cali as the -108 favourites to win. This therefore implies that they have a 52% chance of triumphing. For those wanting to oppose the market leader, you can get +375 about Fluminense.

América and Fluminense can be backed at +190 and +480 respectively on the Half-Time Result market. This is an ideal route for bettors who want a quick settlement and the draw is -125.

For those expecting a low-scoring contest, Under 2.5 is the market leader on the Total Goals market. Both Teams to Score No is available at -294 for anyone expecting at least one side to draw a blank.

If you head to the top football betting sites, you can take your pick when it comes to Copa Sudamericana games. The hundreds of markets always ensure lots of choice.

Full-Time Result

1

-108

X

+188

2

+375

Half-Time Result

1

+190

X

-125

2

+480

Double Chance

1X

-588

12

-270

X2

-130

Draw No Bet

1

-313

2

+200

Asian Handicap

1 Hcp -0.5

-104

2 Hcp +0.5

-119

Total Goals

Under 2.5

-417

Over 2.5

+270

Both Teams to Score

Yes

+200

No

-294

Rodrigo Holgado Favourite to Be First Goalscorer

Rodrigo Holgado is the First Goalscorer favourite at +475 and there’s an opportunity to back him to find the net anytime at +280.

Rodrigo Holgado (América)

First

+280

Anytime

+475

Luis Ramos (América)

First

+370

Anytime

+600

Jan Lucumí (América)

First

+440

Anytime

+700

Sebastian Navarro (América)

First

+450

Anytime

+800

Rafael Carrascal (América)

First

+540

Anytime

+1100

Everaldo Stum (Fluminense)

First

+550

Anytime

+950

Marcos Silva França "Keno" (Fluminense)

First

+750

Anytime

+1300

Agustín Canobbio (Fluminense)

First

+750

Anytime

+1300

Franco Leys (América)

First

+750

Anytime

+1600

Yerson Candelo (América)

First

+1000

Anytime

+2200

Kevin Serna (Fluminense)

First

+1100

Anytime

+1900

Matheus Martinelli (Fluminense)

First

+1100

Anytime

+2000

Paulo Henrique Chagas de Lima "Ganso" (Fluminense)

First

+1100

Anytime

+2200

Facundo Bernal (Fluminense)

First

+1200

Anytime

+2200

Hércules Pereira do Nascimento (Fluminense)

First

+1300

Anytime

+2200

Nonato (Fluminense)

First

+1300

Anytime

+2200

Rodrigo Holgado (América)

Over 2.5

-141

Under 2.5

-

Luis Ramos (América)

Over 2.5

+120

Under 2.5

-

Rafael Carrascal (América)

Over 2.5

-135

Under 2.5

-

Jan Lucumí (América)

Over 1.5

-179

Under 1.5

-

Sebastian Navarro (América)

Over 1.5

-143

Under 1.5

-

Everaldo Stum (Fluminense)

Over 1.5

-123

Under 1.5

-

Marcos Silva França "Keno" (Fluminense)

Over 0.5

-222

Under 0.5

-

Agustín Canobbio (Fluminense)

Over 0.5

-244

Under 0.5

-

Franco Leys (América)

Over 0.5

-179

Under 0.5

-

Yerson Candelo (América)

Over 0.5

-110

Under 0.5

-

Kevin Serna (Fluminense)

Over 0.5

-192

Under 0.5

-

Matheus Martinelli (Fluminense)

Over 0.5

+140

Under 0.5

-

Paulo Henrique Chagas de Lima "Ganso" (Fluminense)

Over 0.5

+190

Under 0.5

-

Facundo Bernal (Fluminense)

Over 0.5

-102

Under 0.5

-

Hércules Pereira do Nascimento (Fluminense)

Over 0.5

+102

Under 0.5

-

Nonato (Fluminense)

Over 0.5

+102

Under 0.5

-

Latest Copa Sudamericana and domestic league stats. Full Time Result, Goals, Corners and Possession.

América de Cali Stats

Fluminense Stats

Full-Time Result

• 3 wins, 3 defeats and 4 draws in the previous 10 matches
• 6 wins, 2 defeats and 2 draws in the previous 10 home matches

Full-Time Result

• 3 wins, 5 defeats and 2 draws in the previous 10 matches
• 3 wins, 5 defeats and 2 draws in the previous 10 away matches

Goals

• An average of 1.00 goals scored and 1.10 conceded in the previous 10 matches
• An average of 1.40 goals scored and 0.70 conceded in the previous 10 home matches
• An average of 2.10 goals per game in the previous 10 matches
• An average of 2.10 goals per game in the previous 10 home matches
• BTTS Yes in 7 of the previous 10 matches
• BTTS Yes in 4 of the previous 10 home matches
• Over 2.5 Goals in 4 of the previous 10 matches
• Over 2.5 Goals in 4 of the previous 10 home matches

Goals

• An average of 1.30 goals scored and 1.60 conceded in the previous 10 matches
• An average of 1.20 goals scored and 1.50 conceded in the previous 10 away matches
• An average of 2.90 goals per game in the previous 10 matches
• An average of 2.70 goals per game in the previous 10 away matches
• BTTS Yes in 6 of the previous 10 matches
• BTTS Yes in 4 of the previous 10 away matches
• Over 2.5 Goals in 5 of the previous 10 matches
• Over 2.5 Goals in 3 of the previous 10 away matches

América de Cali vs Fluminense Lineups & Team News

Before making your bets, take a look at the América vs Fluminense team news. We’ll have the predicted and confirmed Copa Sudamericana lineups for you plus all the latest on player injuries.