América de Cali vs Fluminense Prediction, Betting Tips & Odds | 12 Aug 2025

Copa Sudamericana Betting Preview: América de Cali vs Fluminense

Colombian Categoria Primera A outfit América de Cali host Brazilian Série A side Fluminense in the first leg of this Copa Sudamericana round of 16 tie at Estadio Pascual Guerrero, with kick-off set for 20:30 on Tuesday 12 August 2025. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats and team news.

Big Flu Should Compete Favourably

Fluminense look a nice wager to topple América de Cali and we can take them at -179 with a +0.25 goal headstart on the Asian Handicap. This means dividing our stake equally between 0 and +0.5 in the hope of a payout.

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América Bidding to Bounce Back After Loss

América de Cali fell to a 1-0 home defeat against Deportes Tolima in their most recent outing. Los Diablos Rojos enjoyed 57% possession but managed just one shot on target in a frustrating Primera A performance.

Fluminense drew 3-3 in their previous game. This took place on their travels against Bahia in Série A. The Big Flu had 40% possession and five shots on goal, while German Cano was on the scoresheet twice and Nonato also found the net.

Copa Sudamericana		G	W	D	L	GF	GA	GD	GD	P
2	América de Cali	6	1	5	0	6	4	2	6:4	8
1	Fluminense	6	4	1	1	11	2	9	11:2	13

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América de Cali vs Fluminense Prediction & Betting Tips

The América de Cali vs Fluminense betting tips feature sharp analysis across major markets, including a key match prediction, player prop bets, correct score guidance and a ready-made bet builder.

Match Prediction

We’re siding with Fluminense at -179 in this Copa Sudamericana match with a +0.25 goal advantage. It’s expected that they will have an edge and we can therefore feel bullish of a return with this wager.

Our job is to consult the latest Copa Sudamericana team news in order to produce the best football predictions. Then we crack on with the job of analysing the stats that are going to be the most effective.

Key América de Cali vs Fluminense Copa Sudamericana & league stats:

• The +0.25 line has been covered by Fluminense in 13 of their last 20 games.
• The +0.25 line has been covered by Fluminense in 6 of their last 10 games.
• The +0.25 line has been covered by Fluminense in 2 consecutive games.
• The -0.25 line hasn’t been covered by América in 7 of their last 10 games.
• The -0.25 line hasn’t been covered by América in 12 of their last 20 games.
• The -0.25 line hasn’t been covered by América in 2 consecutive games.

Fluminense +0.25 Probability

Based on the odds from the best betting apps, our pick carries a 64.1% chance of winning. However, our experts think that the probability is close to 70% taking all factors into consideration. This is why we can recommend this wager.

Lots of bettors wanting to back Fluminense to cover the line will look to combine this pick in a Bet Builder. This provides you with the opportunity to secure a bigger price by featuring a number of selections.

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Our Match Prediction

Fluminense Asian Hcp +0.25 @ -179 Watch Live Bet Now

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Correct Score Prediction

América 0 - 1 Fluminense

We’re going for Fluminense at +550 to secure a 1-0 win. It’s exciting to bet on the correct score and this wager will hopefully be able to land a nice return.

Player Prop Picks

Top Pick: Kevin Serna to Score +650

Kevin Serna (Fluminense) has racked up two goals in his past nine matches. We think this is the pick of the player props, with a generous +650 available when it comes to backing him to score at any time.

Latest Kevin Serna Player Prop Odds

Goalscorer

Anytime

+650

First

+1200

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América de Cali vs Fluminense Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Latest Match Odds Suggest a Close-Run Battle

The draw is currently trading at +190 if you think this Copa Sudamericana encounter will end all square, while América de Cali have betting odds of +170 and Fluminense are +175 to land a victory of their own.

If you want to back the favourites with some insurance, then América are -120 on the Draw No Bet market. Alternatively, Fluminense are -118 and there is money back if the game ends all square.

For those expecting a low-scoring contest, Under 2.5 is the market leader on the Total Goals market. Both Teams to Score No is available at -154 for anyone expecting at least one side to draw a blank.

If you head to the top football betting sites, you can take your pick when it comes to Copa Sudamericana games. The hundreds of markets always ensure lots of choice.

Full-Time Result

1

+170

X

+190

2

+175

Half-Time Result

1

+255

X

-105

2

+255

Double Chance

1X

-250

12

-270

X2

-238

Draw No Bet

1

-120

2

-118

Asian Handicap

1 Hcp -0.25

+120

2 Hcp +0.25

-172

Total Goals

Under 2.5

-227

Over 2.5

+163

Both Teams to Score

Yes

+110

No

-154

Rodrigo Holgado Favourite to Be First Goalscorer

Rodrigo Holgado is the First Goalscorer favourite at +650 and there’s an opportunity to back him to find the net anytime at +340.

Rodrigo Holgado (América)

First

+340

Anytime

+650

Everaldo Stum (Fluminense)

First

+360

Anytime

+650

Luis Ramos (América)

First

+380

Anytime

+750

Jan Lucumí (América)

First

+450

Anytime

+900

Marcos Silva França "Keno" (Fluminense)

First

+475

Anytime

+850

Sebastian Navarro (América)

First

+475

Anytime

+950

Agustín Canobbio (Fluminense)

First

+480

Anytime

+850

Rafael Carrascal (América)

First

+575

Anytime

+1300

Kevin Serna (Fluminense)

First

+650

Anytime

+1200

Franco Leys (América)

First

+800

Anytime

+1900

Nonato (Fluminense)

First

+900

Anytime

+1800

Yerson Candelo (América)

First

+950

Anytime

+2200

Matheus Martinelli (Fluminense)

First

+1100

Anytime

+2000

Paulo Henrique Chagas de Lima "Ganso" (Fluminense)

First

+1100

Anytime

+2200

Facundo Bernal (Fluminense)

First

+1150

Anytime

+2000

Hércules Pereira do Nascimento (Fluminense)

First

+1150

Anytime

+2200

Latest Copa Sudamericana and domestic league stats. Full Time Result, Goals, Corners and Possession.

América de Cali Stats

Fluminense Stats

Full-Time Result

• 3 wins, 3 defeats and 4 draws in the previous 10 matches
• 6 wins, 2 defeats and 2 draws in the previous 10 home matches

Full-Time Result

• 3 wins, 5 defeats and 2 draws in the previous 10 matches
• 3 wins, 5 defeats and 2 draws in the previous 10 away matches

Goals

• An average of 1.00 goals scored and 1.10 conceded in the previous 10 matches
• An average of 1.40 goals scored and 0.70 conceded in the previous 10 home matches
• An average of 2.10 goals per game in the previous 10 matches
• An average of 2.10 goals per game in the previous 10 home matches
• BTTS Yes in 7 of the previous 10 matches
• BTTS Yes in 4 of the previous 10 home matches
• Over 2.5 Goals in 4 of the previous 10 matches
• Over 2.5 Goals in 4 of the previous 10 home matches

Goals

• An average of 1.30 goals scored and 1.60 conceded in the previous 10 matches
• An average of 1.20 goals scored and 1.50 conceded in the previous 10 away matches
• An average of 2.90 goals per game in the previous 10 matches
• An average of 2.70 goals per game in the previous 10 away matches
• BTTS Yes in 6 of the previous 10 matches
• BTTS Yes in 4 of the previous 10 away matches
• Over 2.5 Goals in 5 of the previous 10 matches
• Over 2.5 Goals in 3 of the previous 10 away matches

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América de Cali vs Fluminense Lineups & Team News

Before making your bets, take a look at the América vs Fluminense team news. Get the confirmed Copa Sudamericana lineups and the most recent injury news from us.