Atlético Nacional vs Santa Fe Prediction, Betting Tips & Odds | 25 Jul 2025

Primera A Betting Preview: Atlético Nacional vs Santa Fe

Atlético Nacional host Santa Fe in this Colombian Categoría Primera A match, with kick-off set for 21:30 on Friday 25 July 2025. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats and team news.

Santa Fe Should Compete Favourably

We’re siding with Santa Fe on the Asian Handicap +1 at -103, with a confident feeling that they can win or draw when going up against Atlético Nacional. There’s the bonus of a one-goal defeat meaning our stake is refunded.

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Nacional 2-1 Victors When Teams Met Last

Atlético Nacional lost away from home in their last game. Deportivo Pereira won 2-1.

Santa Fe played Águilas Doradas at home in their previous game. It was a 0-0 draw.

Head-to-Head Statistics

The last encounter between Nacional and Santa Fe saw the former triumph away. It was a 2-1 scoreline. We’ve seen five Nacional wins, one Santa Fe victory and four draws for the past 10 matches involving these teams.

Categoria Primera A		G	W	D	L	GF	GA	GD	GD	P
3	Atlético Nacional	3	2	0	1	7	4	3	7:4	6
4	Santa Fe	3	1	2	0	3	2	1	3:2	5

View Full Table

Atlético Nacional vs Santa Fe Prediction & Betting Tips

Head into Atlético Nacional vs Santa Fe with expert betting insights, including our main match prediction, expected scoreline, key player prop picks and a thoughtfully built bet builder.

Match Prediction

We will take Santa Fe +1 for this Primera A clash at -103. This means a nice return from this wager if they win or draw and we think the visitors have the potential to get the right result.

We study the Primera A form as a first port of call and also make sure we’re across any injuries before making our football predictions. Then it’s a case of understanding the sort of narrative that the stats provide.

Key Atlético Nacional vs Santa Fe league stats:

• The +1 line has been covered by Santa Fe in 7 consecutive games.
• The +1 line has been covered by Santa Fe in 9 of their last 10 games.
• The +1 line has been covered by Santa Fe in 15 of their last 20 games.
• The -1 line hasn’t been covered by Nacional in 8 of their last 10 games.
• The -1 line hasn’t been covered by Nacional in 16 of their last 20 games.
• The -1 line hasn’t been covered by Nacional in 6 of their last 10 games against Santa Fe.

Santa Fe +1 Probability

According to the top betting sites, our pick has a 50.8% chance of landing a return. Taking all factors into consideration, our experts think there’s a stronger chance of success and estimate the probability to be closer to 60%. It is therefore regarded as a value wager.

You have the choice to buy or sell goals depending on which direction you want to move the line. Decide whether or not you want to play it safer or take a riskier option.

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Our Match Prediction

Santa Fe Asian Hcp +1 @ -103 Bet Now

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Correct Score Prediction

Nacional 1 - 1 Santa Fe

The teams can be backed at +700 to play out a 1-1 scoreline. It can be fun to have a wager on the correct score and there’s a big potential return if the bet wins.

Player Prop Picks

Top Pick: Yilmar Andres Velasquez To Score +540

Yilmar Andres Velasquez (Santa Fe) can be backed to be among the goals at +540. It’s worth a gamble on him to be Anytime Goalscorer as there’s plenty of juice in these betting odds.

Latest Yilmar Andres Velasquez Player Prop Odds

Goalscorer

Anytime

+540

First

+1200

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Atlético Nacional vs Santa Fe Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Bookies Taking No Chances With Nacional

The bookmakers take few chances with their latest odds of -278 for Atlético Nacional winning which suggests that they have a 74% chance in this Primera A encounter. If you want to wager on the underdog, Santa Fe have been priced up at +650.

As the name suggests, the Half-Time Result market is settled at the break. Should you take this option, then you can choose between Nacional at -108, Santa Fe at +525 or the draw at +138.

The Total Goals odds suggest that Over 2.5 is a strong probability in this contest. An alternative play could be betting BTTS No where you can get -132 when it comes to the Both Teams to Score No market.

The best football betting sites ensure that customers are able to choose from a wide range of options. It’s no exaggeration that they provide hundreds of markets when it comes to Primera A matches.

Full-Time Result

1

-278

X

+360

2

+650

Half-Time Result

1

-108

X

+138

2

+525

Double Chance

1X

-1429

12

-588

X2

+175

Draw No Bet

1

-833

2

+410

Asian Handicap

1 Hcp -1.25

-109

2 Hcp +1.25

-120

Total Goals

Under 2.5

+102

Over 2.5

-139

Both Teams to Score

Yes

-109

No

-132

Alfredo Morelos is the First Goalscorer Favourite

There’s the chance to back Alfredo Morelos at +295 to be the First Goalscorer. He’s the favourite and available at similar odds to find the net last instead.

Alfredo Morelos (Nacional)

First

+123

Anytime

+295

Marino Hinestroza (Nacional)

First

+180

Anytime

+440

Hugo Rodallega (Santa Fe)

First

+195

Anytime

+460

Edwin Cardona (Nacional)

First

+205

Anytime

+480

Kilian Toscano (Nacional)

First

+255

Anytime

+575

Dairon Asprilla (Nacional)

First

+265

Anytime

+600

Andres Sarmiento (Nacional)

First

+280

Anytime

+600

Juan Torres (Nacional)

First

+310

Anytime

+650

Ángelo Rodríguez (Santa Fe)

First

+480

Anytime

+1050

Mateus Uribe (Nacional)

First

+480

Anytime

+1150

Yilmar Andres Velasquez (Santa Fe)

First

+540

Anytime

+1200

Jorman Campuzano (Nacional)

First

+575

Anytime

+1300

Alexis Zapata (Santa Fe)

First

+575

Anytime

+1200

Juan Manuel Zapata (Nacional)

First

+575

Anytime

+1200

Simon Garcia (Nacional)

First

+600

Anytime

+1300

Andrés Felipe Román (Nacional)

First

+600

Anytime

+1300

Santiago Mosquera (Santa Fe)

First

+600

Anytime

+1400

Edwar López (Santa Fe)

First

+650

Anytime

+1400

Juan Jose Arias (Nacional)

First

+750

Anytime

+1600

Omar Fernandez (Santa Fe)

First

+750

Anytime

+1600

William Tesillo (Nacional)

First

+800

Anytime

+1700

Daniel Torres (Santa Fe)

First

+800

Anytime

+1700

Joan Castro (Nacional)

First

+900

Anytime

+2000

Andres Salazar Osorio (Nacional)

First

+900

Anytime

+2000

Jhojan Torres (Santa Fe)

First

+900

Anytime

+2000

Atlético Nacional vs Santa Fe Lineups & Team News

Before making your bets, take a look at the Nacional vs Santa Fe team news. Expect the confirmed Primera A lineups and all current injury developments from us.

Atlético Nacional Team Page Santa Fe Team Page