Cagliari vs Pisa Prediction, Betting Tips, Lineups & Odds | 21 Dec 2025

Serie A Betting Preview: Cagliari vs Pisa

Cagliari square off against Pisa at Unipol Domus, with kick-off set for 06:30 on Sunday 21 December.

Pisa look a nice wager to topple Cagliari and we can take them at -109 with a +0.25 goal headstart on the Asian Handicap. This means dividing our stake equally between 0 and +0.5 in the hope of a payout.

Ready to follow our Asian Handicap pick? Claim the current BetMGM promo code and learn more about the site in our expert review before you decide where to put your money.

Cagliari were defeated on the road in their last game. Atalanta won 2-1 at Gewiss Stadium. Gli Isolani had one shot on target and 42% possession, with Gianluca Gaetano registering the goal.

Pisa were beaten in their previous three games and the latest was away at Stadio Via del Mare. Lecce claimed a 1-0 victory. The Tuscany outfit recorded 49% possession but failed to have a shot on goal.

Head-to-Head Statistics

Cagliari have gone unbeaten in their past three matches against Pisa, with the last clash seeing a 0-0 Serie B draw played out at Stadio Romeo Anconetani. The previous 3 H2H games have featured two draws and one Cagliari victory.

Serie A		G	W	D	L	GF	GA	GD	GD	P
12	Cagliari	23	7	7	9	28	31	-3	28:31	28
19	Pisa	23	1	11	11	19	40	-21	19:40	14

View Full Table

Cagliari have 1 win, 5 losses and 4 draws, averaging 1.0 goals from 3.3 shots on goal and 7.9 attempts. Fabio Pisacane's team have averaged 44.9% possession, 373.2 passes and 3.4 corners per match, with their opponents getting 1.6 goals from 5.3 shots on goal, 10.8 attempts and 5.0 corners.

Gennaro Borrelli and Sebastiano Esposito lead the way with 3 goals, while Gianluca Gaetano has scored 2. Sebastiano Esposito and Marco Palestra have been top assistors on 2, with goalkeeper Elia Caprile keeping 2 clean sheets.

Pisa have 1 victory, 4 defeats and 5 draws, with an average of 2.2 shots on goal, 8.3 attempts and 0.7 goals. I Nerazzurri average 42.7% possession, 331.2 passes, 2.9 corners awarded and 4.9 corners against, while 1.4 goals have been conceded from 14.9 attempts and 4.6 shots on goal.

M'Bala Nzola and Stefano Moreo have top scored with 2 goals, while Henrik Meister is next on 1. Stefano Moreo, Matteo Tramoni and Mehdi Leris are top assists providers with 1, while Adrian Semper has recorded 3 clean sheets in the previous 10 games.

Confirmed Lineups

Cagliari confirmed lineup (4-3-2-1): Elia Caprile (GK), Marco Palestra, Yerry Mina, Juan Rodriguez, Adam Obert, Michael Folorunsho, Alessandro Deiola, Michel Ndary Adopo, Gianluca Gaetano, Sebastiano Esposito, Semih Kilicsoy.

Pisa confirmed lineup (3-5-2): Adrian Semper (GK), Simone Canestrelli, Antonio Caracciolo, Giovanni Bonfanti, Idrissa Toure, Gabriele Piccinini, Michel Aebischer, Malthe Hoejholt, Samuele Angori, Henrik Meister, Matteo Tramoni.

Cagliari vs Pisa Prediction & Betting Tips

Get set for Cagliari vs Pisa with our full betting breakdown, complete with an expert match prediction, a likely final score, top corners play, player prop picks and a value-driven bet builder.

Match Prediction

Pisa +0.25 on the Asian Handicap looks like a sensible play at a price of -109. They should be able to swerve a loss in this Serie A game and we’re confident that the away team can land a victory.

Our football experts study the form, while injuries and suspensions can also affect the potential outcome. Before coming up with a verdict, we combine this data with the latest Serie A stats.

Key Cagliari vs Pisa league stats:

• The +0.25 line has been covered by Pisa in 6 of their last 10 games.
• The +0.25 line has been covered by Pisa in 3 of their last 5 games on the road.
• The -0.25 line hasn’t been covered by Cagliari in 9 of their last 10 games.
• The -0.25 line hasn’t been covered by Cagliari in 4 of their last 5 games.
• The -0.25 line hasn’t been covered by Cagliari in 2 consecutive games against Pisa.

The best football bookies are estimating that there is a 52.1% likelihood of this pick landing a return. Taking all factors into consideration, our experts think there’s a stronger chance of success and have a probability interval between 55-60%. This wager can therefore be backed with confidence.

There are ways of betting on Pisa to win by a certain number of goals thanks to the Winning Margin market, with this being a nice alternative to Asian Handicap.

Thinking about claiming free bets? Our bonus guide lists the best sign-up offers from the biggest names in betting.

Our Match Prediction

Pisa Asian Hcp +0.25 @ -109 Bet Now

BetMGM Promo Up To $1500 in Bonus Bets Get Bonus T&C apply. Gamble responsibly 18+

Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (12:38, 19 December 2025). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Cagliari 1 - 2 Pisa

Pisa can be backed to win 2-1 when it comes to the correct score. We’ll go for the +1050 that this happens and hopefully we’ll get a good run for our money.

Player Prop Picks

Top Pick: Marco Palestra Over 0.5 Shots -143

Marco Palestra (Cagliari) has bagged one or more shots in three consecutive Serie A matches. We’re anticipating that he is able to perform well and cover the Player Shots line, with odds of -143 currently available.

Latest Marco Palestra Player Prop Odds

Goalscorer

Anytime

+750

First

+1800

Shots On Target

Over 0.5

+220

Under 0.5

-625

Shots

Over 0.5

-208

Under 0.5

-

---

Stefano Moreo to Score +370

Stefano Moreo (Pisa) has netted two goals in his past four Serie A away matches. We believe this is the best of the player props, with a healthy +370 available when it comes to betting him to score at any time.

Latest Stefano Moreo Player Prop Odds

Goalscorer

Anytime

+440

First

+900

Shots On Target

Over 0.5

+112

Under 0.5

-222

Shots

Over 1.5

-119

Under 1.5

-

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Corners Prediction

Pisa Under 3.5 Corners -110

The 3.5 corners line has not been covered by Pisa in six straight away games, while the past two Cagliari home matches have seen under 3.5 corners conceded. For Team Corners, we’re expecting Pisa to fall short and you can land odds of -110.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Cagliari

Total

8.40 3.40 5.00

Home

8.70 4.40 4.30

Away

9.30 3.00 6.30

Pisa

Total

7.80 2.90 4.90

Home

9.00 4.50 4.50

Away

8.80 2.70 6.10

Latest Corner Odds

Total Corners

Over 8.5

-123

Under 8.5

-114

Cagliari Corners

Over 4.5

-156

Under 4.5

+110

Pisa Corners

Over 3.5

-100

Under 3.5

-141

Most Corners

1

-200

X

+600

2

+205

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Cagliari vs Pisa Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The Full-Time Result odds of +106 suggest that Cagliari are likely victors and there’s a 49% probability that the favourites win this Serie A clash. For those wanting to oppose the market leader, you can get +310 about Pisa.

There’s the option to get some insurance on your bet by going down the Draw No Bet route. This allows you to back Cagliari at -244 with a safety net or alternatively opt for Pisa at +163.

A low-scoring contest will be predicted by several which is reflected in the fact that Under 2.5 Goals has the shortest odds. Providing that at least one side fails to score, then the No pick on the Both Teams to Score market will be a winner at -159.

You can find hundreds of markets for every Serie A game, with the best betting sites creating lots of different options. Check out the pre-game and In-Play selections before placing your football bets.

Full-Time Result

1

+106

X

+200

2

+310

Half-Time Result

1

+170

X

+102

2

+340

Double Chance

1X

-435

12

-270

X2

-141

Draw No Bet

1

-244

2

+163

Asian Handicap

1 Hcp -0.5

+106

2 Hcp +0.5

-132

Total Goals

Under 2.5

-222

Over 2.5

+170

Both Teams to Score

Yes

+118

No

-159

Sebastiano Esposito is the market leader to be First Goalscorer at +525. Alternatively, there’s the chance to back him to find the net at any stage at +240.

Sebastiano Esposito (Cagliari)

First

+240

Anytime

+525

Semih Kiliçsoy (Cagliari)

First

+250

Anytime

+525

Zito Luvumbo (Cagliari)

First

+340

Anytime

+750

Matteo Tramoni (Pisa)

First

+400

Anytime

+800

Michael Folorunsho (Cagliari)

First

+410

Anytime

+900

Stefano Moreo (Pisa)

First

+440

Anytime

+900

Gianluca Gaetano (Cagliari)

First

+525

Anytime

+1200

Michel Adopo (Cagliari)

First

+650

Anytime

+1400

Idrissa Touré (Pisa)

First

+650

Anytime

+1500

Marco Palestra (Cagliari)

First

+750

Anytime

+1800

Matteo Prati (Cagliari)

First

+800

Anytime

+1800

Alessandro Deiola (Cagliari)

First

+850

Anytime

+1900

Gabriele Piccinini (Pisa)

First

+850

Anytime

+2000

Luca Mazzitelli (Cagliari)

First

+900

Anytime

+2200

Lorran Lucas Pereira de Sousa (Pisa)

First

+950

Anytime

+2000

Yerry Mina (Cagliari)

First

+950

Anytime

+2200

Mehdi Leris (Pisa)

First

+1000

Anytime

+2200

Marius Mihai Marin (Pisa)

First

+1000

Anytime

+2200

Michel Aebischer (Pisa)

First

+1000

Anytime

+2200

Sebastiano Esposito (Cagliari)

Over 0.5

-263

Under 0.5

+130

Semih Kiliçsoy (Cagliari)

Over 0.5

-179

Under 0.5

-110

Zito Luvumbo (Cagliari)

Over 0.5

-116

Under 0.5

-167

Michael Folorunsho (Cagliari)

Over 0.5

-102

Under 0.5

-192

Matteo Tramoni (Pisa)

Over 0.5

+104

Under 0.5

-208

Stefano Moreo (Pisa)

Over 0.5

+112

Under 0.5

-222

Gianluca Gaetano (Cagliari)

Over 0.5

+138

Under 0.5

-286

Michel Adopo (Cagliari)

Over 0.5

+180

Under 0.5

-417

Idrissa Touré (Pisa)

Over 0.5

+210

Under 0.5

-500

Marco Palestra (Cagliari)

Over 0.5

+220

Under 0.5

-625

Alessandro Deiola (Cagliari)

Over 0.5

+235

Under 0.5

-667

Matteo Prati (Cagliari)

Over 0.5

+240

Under 0.5

-714

Gabriele Piccinini (Pisa)

Over 0.5

+270

Under 0.5

-909

Yerry Mina (Cagliari)

Over 0.5

+280

Under 0.5

-909

Sebastiano Esposito (Cagliari)

Over 3.5

+112

Under 3.5

-

Semih Kiliçsoy (Cagliari)

Over 2.5

+104

Under 2.5

-

Zito Luvumbo (Cagliari)

Over 1.5

-156

Under 1.5

-

Matteo Tramoni (Pisa)

Over 1.5

-130

Under 1.5

-

Michael Folorunsho (Cagliari)

Over 1.5

-137

Under 1.5

-

Stefano Moreo (Pisa)

Over 1.5

-119

Under 1.5

-

Gianluca Gaetano (Cagliari)

Over 1.5

+108

Under 1.5

-

Idrissa Touré (Pisa)

Over 0.5

-217

Under 0.5

-

Marco Palestra (Cagliari)

Over 0.5

-208

Under 0.5

-

Cagliari have five defeats, three victories and two draws in the last 10 home matches, netting an average of 1.30 goals per game and conceding 1.40.

Pisa haven’t triumphed in eight straight games on the road. The Tuscany outfit have clocked up four draws, four losses and two wins in the past 10 away games, recording an average of 1.30 goals per match and conceding 1.70.

Cagliari and Pisa played out a 1-1 draw when the teams last met at Unipol Domus.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Cagliari Home Stats		3-2-5	2.70	1.30	1.40	5	5	5	5
Pisa Away Stats		2-4-4	3.00	1.30	1.70	6	4	6	4

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

Cagliari vs Pisa Lineups & Team News

Get the latest team news for Cagliari vs Pisa before you bet. Expect the predicted and confirmed Serie A lineups along with timely injury updates.

Cagliari Team Page Pisa Team Page

Top Football Pages