Estudiantes vs Cerro Porteño Prediction, Betting Tips, Lineups & Odds | 20 Aug 2025

Copa Libertadores Betting Preview: Estudiantes vs Cerro Porteño

Argentine Primera División club Estudiantes host Paraguayan Primera División side Cerro Porteño in the second leg of this Copa Libertadores round of 16 tie, with kick-off set for 18:00 on Wednesday 20 August 2025. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and confirmed lineups.

Don’t Write Off Cerro Porteño For This Clash

Cerro Porteño +0.75 at -106 on the Asian Handicap looks like a sensible plan of attack, with our stake divided between +0.5 and +1.0 when they clash with Estudiantes. We’re expecting defeat to be avoided.

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Estudiantes 1-0 First Leg Winners

Estudiantes de La Plata were beaten last game and this was away from home. Banfield claimed a 3-2 Argentine Primera División win. Eduardo Dominguez's side had most of the ball enjoying 59% possession and six shots on target, with Santiago Arzamendia and Roman Gomez each scoring one goal.

Cerro Porteño triumphed in their previous game. This was a 4-3 road win against Club Guarani in the Paraguayan Primera División.

Head-to-Head Statistics

Estudiantes beat Cerro Porteño 1-0 away in the first leg, with Santiago Ascacíbar converting a late penalty. The Argentines enjoyed 61% possession, though the hosts won the shots on target 5-3.

Copa Libertadores		G	W	D	L	GF	GA	GD	GD	P
1	Estudiantes	6	4	0	2	11	5	6	11:5	12
2	Cerro Porteño	6	2	1	3	7	11	-4	7:11	7

View Full Table

Estudiantes vs Cerro Porteño Prediction & Betting Tips

We’ve lined up expert Estudiantes vs Cerro Porteño betting tips, from our match prediction and correct score call to player prop picks and best bet builder advice. Read on for the full breakdown.

Match Prediction

Cerro Porteño +0.75 could be the best way forward at odds of -106 in this Copa Libertadores encounter. We feel optimistic that the underdogs can punch above their weight and be tough to beat.

The latest injury and suspension news can have a big bearing and we use this data as well as the latest form guide. We’re also keen to study the football stats so that we can get the fullest picture of how the action might happen.

Key Estudiantes vs Cerro Porteño Copa Libertadores & league stats:

• The +0.75 line has been covered by Cerro Porteño in 5 consecutive games on the road.
• The +0.75 line has been covered by Cerro Porteño in 9 of their last 10 games.
• The +0.75 line has been covered by Cerro Porteño in 16 of their last 20 games.
• The -0.75 line hasn’t been covered by Estudiantes in 12 of their last 20 games.

Cerro Porteño +0.75 Probability

According to the odds, there’s a 51.5% likelihood of our pick winning. Taking all factors into consideration, our tipsters think there’s a stronger chance of success and estimate the probability to be closer to 60%. It’s why we think it’s worth placing this wager.

If you’re looking for a good alternative to backing Cerro Porteño on the Asian Handicap, then consider the Winning Margin market. You can choose from a range of fixed intervals and odds.

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Our Match Prediction

Cerro Porteño Asian Hcp +0.75 @ -106 Watch Live Bet Now

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Correct Score Prediction

Estudiantes 1 - 1 Cerro Porteño

An exciting wager could be the game to end in a 1-1 draw at odds of +600. A correct score bet provides a fun alternative and a nice potential return on the cards.

Player Prop Picks

Leonardo Suarez Under 0.5 Shots On Target -161

Leonardo Suarez (Estudiantes) is available at -161 to finish without a shot on goal. He stands out as a value pick when it comes to Shots on Target, with the recommendation being to wager this player prop pick.

Latest Leonardo Suarez Player Prop Odds

Goalscorer

Anytime

+350

First

+700

Shots On Target

Over 0.5

+112

Under 0.5

-161

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Tiago Palacios to Score +330

Tiago Palacios (Estudiantes) has scored three goals in his past nine matches. We’ll bear these numbers in mind and take odds of +330 that he is able to feature on the scoresheet when we wager on Anytime Goalscorer.

Latest Tiago Palacios Player Prop Odds

Goalscorer

Anytime

+330

First

+600

Shots On Target

Over 0.5

-125

Under 0.5

-115

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Estudiantes vs Cerro Porteño Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Bookies Make Estudiantes Favourites to Win

Estudiantes are the shortest price to win this Copa Libertadores clash according to the bookies, with the favourites given a 62% probability due to their -161 betting odds. If you’re interested in wagering Cerro Porteño, you can get +475 for the underdog.

If you want to back the favourites to be ahead by the break, then Estudiantes are +128 on the Half-Time Result market. Alternatively, Cerro Porteño are +475 and the draw is priced at +118.

For those anticipating a low-scoring contest, Under 2.5 is the market leader for the Total Goals market. A different angle is going for a BTTS wager and there’s -164 available for Both Teams to Score No.

There are hundreds of markets from which to select your preferred wager when it comes to Copa Libertadores games. The best football betting sites push the boat out to provide lots of choice.

Full-Time Result

1

-161

X

+290

2

+475

Half-Time Result

1

+128

X

+118

2

+475

Double Chance

1X

-625

12

-370

X2

+130

Draw No Bet

1

-455

2

+280

Asian Handicap

1 Hcp -0.75

-133

2 Hcp +0.75

-106

Total Goals

Under 2.5

-152

Over 2.5

+123

Both Teams to Score

Yes

+117

No

-164

Guido Carrillo Favourite to Find the Net First

Guido Carrillo is available at +235 when it comes to Anytime Goalscorer. The favourite is now priced at odds of +480 to find the net first.

Guido Carrillo (Estudiantes)

First

+235

Anytime

+480

Tiago Palacios (Estudiantes)

First

+330

Anytime

+600

Lucas Alario (Estudiantes)

First

+350

Anytime

+700

Leonardo Suarez (Estudiantes)

First

+350

Anytime

+700

Edwuin Cetré (Estudiantes)

First

+350

Anytime

+700

Joaquín Tobio Burgos (Estudiantes)

First

+370

Anytime

+700

Jonathan Gabriel Torres (Cerro Porteño)

First

+400

Anytime

+1000

Santiago Ascacibar (Estudiantes)

First

+410

Anytime

+800

José Ernesto Sosa (Estudiantes)

First

+550

Anytime

+1150

Cristian Medina (Estudiantes)

First

+600

Anytime

+1300

Juan Iturbe (Cerro Porteño)

First

+650

Anytime

+1200

Cecilio Domínguez (Cerro Porteño)

First

+700

Anytime

+1400

Sergio Araujo (Cerro Porteño)

First

+700

Anytime

+1400

Gabriel Aguayo (Cerro Porteño)

First

+700

Anytime

+1700

Federico Carrizo (Cerro Porteño)

First

+800

Anytime

+1600

Santiago Arzamendia (Estudiantes)

First

+850

Anytime

+1800

Robert Piris da Motta (Cerro Porteño)

First

+1050

Anytime

+2000

Guido Carrillo (Estudiantes)

Over 0.5

-185

Under 0.5

+130

Jonathan Gabriel Torres (Cerro Porteño)

Over 0.5

-152

Under 0.5

-112

Tiago Palacios (Estudiantes)

Over 0.5

-125

Under 0.5

-115

Edwuin Cetré (Estudiantes)

Over 0.5

-123

Under 0.5

-115

Lucas Alario (Estudiantes)

Over 0.5

-111

Under 0.5

-127

Joaquín Tobio Burgos (Estudiantes)

Over 0.5

-109

Under 0.5

-130

Leonardo Suarez (Estudiantes)

Over 0.5

+112

Under 0.5

-161

Cecilio Domínguez (Cerro Porteño)

Over 0.5

+117

Under 0.5

-172

Santiago Ascacibar (Estudiantes)

Over 0.5

+120

Under 0.5

-172

Juan Iturbe (Cerro Porteño)

Over 0.5

+140

Under 0.5

-204

Gabriel Aguayo (Cerro Porteño)

Over 0.5

+155

Under 0.5

-278

Sergio Araujo (Cerro Porteño)

Over 0.5

+155

Under 0.5

-233

Cristian Medina (Estudiantes)

Over 0.5

+160

Under 0.5

-233

José Ernesto Sosa (Estudiantes)

Over 0.5

+170

Under 0.5

-250

Federico Carrizo (Cerro Porteño)

Over 0.5

+195

Under 0.5

-286

Robert Piris da Motta (Cerro Porteño)

Over 0.5

+210

Under 0.5

-313

Santiago Arzamendia (Estudiantes)

Over 0.5

+255

Under 0.5

-417

Latest Copa Libertadores and domestic league stats. Full Time Result, Goals, Corners and Possession.

Estudiantes Stats

Cerro Porteño Stats

Full-Time Result

• 3 wins, 5 defeats and 2 draws in the previous 10 matches
• 6 wins, 1 defeat and 3 draws in the previous 10 home matches

Full-Time Result

• 7 wins and 3 draws in the previous 10 matches
• 8 wins, 1 defeat and 1 draw in the previous 10 away matches

Goals

• An average of 0.80 goals scored and 1.50 conceded in the previous 10 matches
• An average of 1.60 goals scored and 0.90 conceded in the previous 10 home matches
• An average of 2.30 goals per game in the previous 10 matches
• An average of 2.50 goals per game in the previous 10 home matches
• BTTS Yes in 4 of the previous 10 matches
• BTTS Yes in 6 of the previous 10 home matches
• Over 2.5 Goals in 4 of the previous 10 matches
• Over 2.5 Goals in 5 of the previous 10 home matches

Goals

• An average of 2.40 goals scored and 1.10 conceded in the previous 10 matches
• An average of 2.50 goals scored and 1.00 conceded in the previous 10 away matches
• An average of 3.50 goals per game in the previous 10 matches
• An average of 3.50 goals per game in the previous 10 away matches
• BTTS Yes in 7 of the previous 10 matches
• BTTS Yes in 6 of the previous 10 away matches
• Over 2.5 Goals in 6 of the previous 10 matches
• Over 2.5 Goals in 6 of the previous 10 away matches

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Estudiantes vs Cerro Porteño Lineups & Team News

The latest Estudiantes vs Cerro Porteño team news could impact your bets — review it first. Stay informed with our predicted and confirmed Copa Libertadores lineups and the latest injury reports.