Estudiantes vs Cerro Porteño Prediction, Betting Tips, Lineups & Odds | 20 Aug 2025

Copa Libertadores Betting Preview: Estudiantes vs Cerro Porteño

Argentine Primera División club Estudiantes host Paraguayan Primera División side Cerro Porteño in the second leg of this Copa Libertadores round of 16 tie, with kick-off set for 18:00 on Wednesday 20 August. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and confirmed lineups.

Don’t Write Off Cerro Porteño For This Clash

Cerro Porteño +0.75 at -106 on the Asian Handicap looks like a sensible plan of attack, with our stake divided between +0.5 and +1.0 when they clash with Estudiantes. We’re expecting defeat to be avoided.

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Estudiantes 1-0 First Leg Winners

Estudiantes de La Plata were beaten last game and this was away from home. Banfield claimed a 3-2 Argentine Primera División win. Eduardo Dominguez's side had most of the ball enjoying 59% possession and six shots on target, with Santiago Arzamendia and Roman Gomez each scoring one goal.

Cerro Porteño triumphed in their previous game. This was a 4-3 road win against Club Guarani in the Paraguayan Primera División.

Head-to-Head Statistics

Estudiantes beat Cerro Porteño 1-0 away in the first leg, with Santiago Ascacíbar converting a late penalty. The Argentines enjoyed 61% possession, though the hosts won the shots on target 5-3.

Copa Libertadores		G	W	D	L	GF	GA	GD	GD	P
1	Estudiantes	6	4	0	2	11	5	6	11:5	12
2	Cerro Porteño	6	2	1	3	7	11	-4	7:11	7

View Full Table

Confirmed Lineups

Estudiantes confirmed lineup (4-2-3-1): Fernando Muslera (GK), Roman Gomez, Leandro Gonzalez Pirez, Facundo Rodriguez, Santiago Arzamendia, Mikel Amondarain, Cristian Medina, Tiago Palacios, Santiago Ascacibar, Alexis Castro, Guido Carrillo.

Cerro Porteño confirmed lineup (4-2-3-1): Alexis Arias (GK), Fabricio Dominguez, Lucas Quintana, Matias Perez, Blas Riveros, Robert Piris, Jorge Morel, Juan Iturbe, Federico Carrizo, Ignacio Aliseda, Jonathan Torres.

Estudiantes vs Cerro Porteño Prediction & Betting Tips

We’ve lined up expert Estudiantes vs Cerro Porteño betting tips, from our match prediction and correct score call to player prop picks and best bet builder advice. Read on for the full breakdown.

Match Prediction

Cerro Porteño +0.75 could be the best way forward at odds of -106 in this Copa Libertadores encounter. We feel optimistic that the underdogs can punch above their weight and be tough to beat.

The latest injury and suspension news can have a big bearing and we use this data as well as the latest form guide. We’re also keen to study the football stats so that we can get the fullest picture of how the action might happen.

Key Estudiantes vs Cerro Porteño Copa Libertadores & league stats:

• The +0.75 line has been covered by Cerro Porteño in 5 consecutive games on the road.
• The +0.75 line has been covered by Cerro Porteño in 9 of their last 10 games.
• The +0.75 line has been covered by Cerro Porteño in 16 of their last 20 games.
• The -0.75 line hasn’t been covered by Estudiantes in 12 of their last 20 games.

Cerro Porteño +0.75 Probability

According to the odds, there’s a 51.5% likelihood of our pick winning. Taking all factors into consideration, our tipsters think there’s a stronger chance of success and estimate the probability to be closer to 60%. It’s why we think it’s worth placing this wager.

If you’re looking for a good alternative to backing Cerro Porteño on the Asian Handicap, then consider the Winning Margin market. You can choose from a range of fixed intervals and odds.

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Our Match Prediction

Cerro Porteño Asian Hcp +0.75 @ -106 Bet Now

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Correct Score Prediction

Estudiantes 1 - 1 Cerro Porteño

An exciting wager could be the game to end in a 1-1 draw at odds of +525. A correct score bet provides a fun alternative and a nice potential return on the cards.

Player Prop Picks

Top Pick: Leonardo Suarez Under 0.5 Shots On Target -161

Leonardo Suarez (Estudiantes) is available at -161 to finish without a shot on goal. He stands out as a value pick when it comes to Shots on Target, with the recommendation being to wager this player prop pick.

Latest Leonardo Suarez Player Prop Odds

Goalscorer

Anytime

+370

First

+750

Shots On Target

Over 0.5

+123

Under 0.5

-179

Shots

Over 1.5

+135

Under 1.5

-

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Tiago Palacios to Score +330

Tiago Palacios (Estudiantes) has scored three goals in his past nine matches. We’ll bear these numbers in mind and take odds of +330 that he is able to feature on the scoresheet when we wager on Anytime Goalscorer.

Latest Tiago Palacios Player Prop Odds

Goalscorer

Anytime

+300

First

+650

Shots On Target

Over 0.5

-127

Under 0.5

-133

Shots

Over 1.5

-200

Under 1.5

-

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Estudiantes vs Cerro Porteño Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Bookies Make Estudiantes Favourites to Win

Estudiantes are the shortest price to win this Copa Libertadores clash according to the bookies, with the favourites given a 58% probability due to their -141 betting odds. If you’re interested in wagering Cerro Porteño, you can get +450 for the underdog.

If you want to back the favourites to be ahead by the break, then Estudiantes are +138 on the Half-Time Result market. Alternatively, Cerro Porteño are +450 and the draw is priced at +110.

For those anticipating a low-scoring contest, Under 2.5 is the market leader for the Total Goals market. A different angle is going for a BTTS wager and there’s -164 available for Both Teams to Score No.

There are hundreds of markets from which to select your preferred wager when it comes to Copa Libertadores games. The best football betting sites push the boat out to provide lots of choice.

Full-Time Result

1

-141

X

+250

2

+450

Half-Time Result

1

+138

X

+110

2

+450

Double Chance

1X

-588

12

-313

X2

+115

Draw No Bet

1

-417

2

+255

Asian Handicap

1 Hcp -0.75

-116

2 Hcp +0.75

-122

Total Goals

Under 2.5

-172

Over 2.5

+135

Both Teams to Score

Yes

+117

No

-164

Guido Carrillo Favourite to Find the Net First

Guido Carrillo is available at +170 when it comes to Anytime Goalscorer. The favourite is now priced at odds of +410 to find the net first.

Guido Carrillo (Estudiantes)

First

+170

Anytime

+410

Tiago Palacios (Estudiantes)

First

+300

Anytime

+650

Lucas Alario (Estudiantes)

First

+350

Anytime

+700

Edwuin Cetré (Estudiantes)

First

+370

Anytime

+700

Leonardo Suarez (Estudiantes)

First

+370

Anytime

+750

Santiago Ascacibar (Estudiantes)

First

+370

Anytime

+850

Joaquín Tobio Burgos (Estudiantes)

First

+390

Anytime

+750

Jonathan Gabriel Torres (Cerro Porteño)

First

+400

Anytime

+900

Cristian Medina (Estudiantes)

First

+575

Anytime

+1400

Juan Iturbe (Cerro Porteño)

First

+575

Anytime

+1200

José Ernesto Sosa (Estudiantes)

First

+600

Anytime

+1200

Cecilio Domínguez (Cerro Porteño)

First

+700

Anytime

+1300

Sergio Araujo (Cerro Porteño)

First

+700

Anytime

+1400

Federico Carrizo (Cerro Porteño)

First

+700

Anytime

+1500

Gabriel Aguayo (Cerro Porteño)

First

+700

Anytime

+1600

Santiago Arzamendia (Estudiantes)

First

+800

Anytime

+1900

Robert Piris da Motta (Cerro Porteño)

First

+900

Anytime

+2000

Guido Carrillo (Estudiantes)

Over 0.5

-213

Under 0.5

+123

Jonathan Gabriel Torres (Cerro Porteño)

Over 0.5

-143

Under 0.5

-118

Tiago Palacios (Estudiantes)

Over 0.5

-127

Under 0.5

-133

Edwuin Cetré (Estudiantes)

Over 0.5

-118

Under 0.5

-120

Lucas Alario (Estudiantes)

Over 0.5

-106

Under 0.5

-133

Joaquín Tobio Burgos (Estudiantes)

Over 0.5

+102

Under 0.5

-147

Santiago Ascacibar (Estudiantes)

Over 0.5

+112

Under 0.5

-192

Juan Iturbe (Cerro Porteño)

Over 0.5

+120

Under 0.5

-208

Leonardo Suarez (Estudiantes)

Over 0.5

+123

Under 0.5

-179

Cecilio Domínguez (Cerro Porteño)

Over 0.5

+125

Under 0.5

-182

Sergio Araujo (Cerro Porteño)

Over 0.5

+160

Under 0.5

-238

Gabriel Aguayo (Cerro Porteño)

Over 0.5

+160

Under 0.5

-294

Cristian Medina (Estudiantes)

Over 0.5

+165

Under 0.5

-303

Federico Carrizo (Cerro Porteño)

Over 0.5

+175

Under 0.5

-333

José Ernesto Sosa (Estudiantes)

Over 0.5

+185

Under 0.5

-278

Robert Piris da Motta (Cerro Porteño)

Over 0.5

+245

Under 0.5

-526

Santiago Arzamendia (Estudiantes)

Over 0.5

+255

Under 0.5

-556

Guido Carrillo (Estudiantes)

Over 2.5

+108

Under 2.5

-

Jonathan Gabriel Torres (Cerro Porteño)

Over 2.5

+138

Under 2.5

-

Gabriel Aguayo (Cerro Porteño)

Over 1.5

+155

Under 1.5

-

Cecilio Domínguez (Cerro Porteño)

Over 1.5

-114

Under 1.5

-

Juan Iturbe (Cerro Porteño)

Over 1.5

-147

Under 1.5

-

Tiago Palacios (Estudiantes)

Over 1.5

-200

Under 1.5

-

Cristian Medina (Estudiantes)

Over 1.5

+145

Under 1.5

-

Joaquín Tobio Burgos (Estudiantes)

Over 1.5

-115

Under 1.5

-

Santiago Ascacibar (Estudiantes)

Over 1.5

-122

Under 1.5

-

Leonardo Suarez (Estudiantes)

Over 1.5

+135

Under 1.5

-

Edwuin Cetré (Estudiantes)

Over 1.5

-179

Under 1.5

-

Lucas Alario (Estudiantes)

Over 1.5

-114

Under 1.5

-

José Ernesto Sosa (Estudiantes)

Over 0.5

-233

Under 0.5

-

Sergio Araujo (Cerro Porteño)

Over 0.5

-238

Under 0.5

-

Federico Carrizo (Cerro Porteño)

Over 0.5

-238

Under 0.5

-

Santiago Arzamendia (Estudiantes)

Over 0.5

-192

Under 0.5

-

Robert Piris da Motta (Cerro Porteño)

Over 0.5

-208

Under 0.5

-

Latest Copa Libertadores and domestic league stats. Full Time Result, Goals, Corners and Possession.

Estudiantes Stats

Cerro Porteño Stats

Full-Time Result

• 3 wins, 5 defeats and 2 draws in the previous 10 matches
• 6 wins, 1 defeat and 3 draws in the previous 10 home matches

Full-Time Result

• 7 wins and 3 draws in the previous 10 matches
• 8 wins, 1 defeat and 1 draw in the previous 10 away matches

Goals

• An average of 0.80 goals scored and 1.50 conceded in the previous 10 matches
• An average of 1.60 goals scored and 0.90 conceded in the previous 10 home matches
• An average of 2.30 goals per game in the previous 10 matches
• An average of 2.50 goals per game in the previous 10 home matches
• BTTS Yes in 4 of the previous 10 matches
• BTTS Yes in 6 of the previous 10 home matches
• Over 2.5 Goals in 4 of the previous 10 matches
• Over 2.5 Goals in 5 of the previous 10 home matches

Goals

• An average of 2.40 goals scored and 1.10 conceded in the previous 10 matches
• An average of 2.50 goals scored and 1.00 conceded in the previous 10 away matches
• An average of 3.50 goals per game in the previous 10 matches
• An average of 3.50 goals per game in the previous 10 away matches
• BTTS Yes in 7 of the previous 10 matches
• BTTS Yes in 6 of the previous 10 away matches
• Over 2.5 Goals in 6 of the previous 10 matches
• Over 2.5 Goals in 6 of the previous 10 away matches

Estudiantes vs Cerro Porteño Lineups & Team News

The latest Estudiantes vs Cerro Porteño team news could impact your bets — review it first. Stay informed with our predicted and confirmed Copa Libertadores lineups and the latest injury reports.