Estudiantes vs Flamengo Prediction, Betting Tips, Lineups & Odds | 25 Sep 2025

Copa Libertadores Betting Preview: Estudiantes vs Flamengo

Argentine Primera División club Estudiantes host Brazilian Série A team Flamengo in the second leg of this Copa Libertadores quarter-final tie, with kick-off set for 20:30 on Thursday 25 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and confirmed lineups.

We think that Flamengo will have the upper hand against Estudiantes and we like the price of +114 on the Full-Time Result market. The odds make plenty of appeal and we’re expecting this bet to land.

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Estudiantes de La Plata won their last game, beating Defensa y Justicia 1-0 at home in the Primera División. Los Pincharratas had most of the ball boasting 59% possession and three shots on target, with an own goal proving to be the difference in the end.

Flamengo played out a 1-1 draw against Vasco da Gama in their previous game, with this being at home in the Série A. Filipe Luis' team boasted 61% possession and had three shots on goal, while Jorge Carrascal found the net.

Head-to-Head Statistics

Flamengo secured a 2-1 victory at home in the first leg against Estudiantes. The Brazilian side enjoyed 56% possession and won the shots on target 8-3, with Gullermo Varela and Gonzalo Plata on the scoresheet. Léo Pereira struck in injury time for the visitors.

Copa Libertadores		G	W	D	L	GF	GA	GD	GD	P
1	Estudiantes	6	4	0	2	11	5	6	11:5	12
2	Flamengo	6	3	2	1	6	3	3	6:3	11

View Full Table

5 wins and 5 losses, averaging 1.0 goals from 3.8 shots on goal and 7.7 attempts. Estudiantes have had 55.2% possession and 4.7 corners per game. On average, Eduardo Dominguez's men have conceded 1.2 goals from 4.4 shots on goal and 9.5 attempts, while the opposition have been awarded 4.9 corners.

Top goalscorer Leandro Gonzalez Pirez has found the net 2 times, with Santiago Nunez, Santiago Arzamendia, Roman Gomez and Fabricio Perez scoring 1 each. Edwuin Cetre is the leading assists maker on 3.

Flamengo have 7 victories and 3 draws, with an average of 5.1 shots on goal, 11.8 attempts and 2.2 goals. The Rio de Janeiro club average 64.0% possession, 6.9 corners taken and 4.9 corners against them, while 0.6 goals have been conceded from 7.6 attempts and 3.1 shots on goal.

Pedro is the leading scorer with 6 goals, followed by Giorgian De Arrascaeta on 4, with Samuel Dias Lino and two others bagging 2. Giorgian De Arrascaeta has managed to clock up 6 assists in the last 10 games.

Confirmed Lineups

Estudiantes confirmed lineup (4-2-3-1): Fernando Muslera (GK), Roman Gomez, Santiago Nunez, Facundo Rodriguez, Santiago Arzamendia, Gaston Benedetti, Mikel Amondarain, Tiago Palacios, Santiago Ascacibar, Cristian Medina, Guido Carrillo.

Flamengo confirmed lineup (4-2-3-1): Agustin Rossi (GK), Guillermo Varela, Leo Ortiz, Leo Pereira, Alex Sandro, Jorginho, Saul Niguez, Gonzalo Plata, Giorgian De Arrascaeta, Samuel Dias Lino, Pedro.

Estudiantes vs Flamengo Prediction & Betting Tips

Discover the top Estudiantes vs Flamengo betting angles — from our trusted match prediction and likely score to the best prop plays and a customized bet builder.

Match Prediction

Flamengo can land a return and we’ll confidently wager them for this Copa Libertadores game. The odds of +114 look appealing when it comes to this pick, with a confident bet being made.

The first step involves analysing the form and also getting an idea of the injury situation before making any football picks. Then it’s a case of consulting the latest Copa Libertadores stats and seeing if they can inform our opinion.

Key Estudiantes vs Flamengo Copa Libertadores & league stats:

• Flamengo have won 4 of their last 5 games on the road.
• Flamengo have won 15 of their last 20 games.
• Flamengo have won 3 consecutive games on the road.
• Estudiantes have lost 3 of their last 5 games.

When you look at the latest odds, our pick has a 46.7% chance of winning. Based on our tipsters research, we calculate the actual probability to be 50-55%. This wager can therefore be backed with confidence.

There is a an attractive wagering alternative that permits you to pair Flamengo to win with both teams to find the net. It’s a case of heading to the Result + BTTS market to land a bigger price.

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Our Match Prediction

Flamengo To Win @ +114 Bet Now

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Correct Score Prediction

Estudiantes 0 - 1 Flamengo

We’ve found an attractive bet at odds of +525 and it involves Flamengo winning 1-0. We like a wager on correct score as there’s the chance to bank a bigger return.

Player Prop Picks

Top Pick: Guido Carrillo Over 0.5 Shots On Target -164

Guido Carrillo (Estudiantes) can be backed to finish with at least one shot on goal at -164. He looks like an attractive wager on the Shots on Target market and we recommend backing this player prop bet selection.

Latest Guido Carrillo Player Prop Odds

Goalscorer

Anytime

+310

First

+700

Shots On Target

Over 0.5

-167

Under 0.5

-100

Shots

Over 2.5

-109

Under 2.5

-

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Samuel Lino to Score +380

Samuel Lino (Flamengo) has managed two goals in his past five games. We’ll take a chance at +380 for this Anytime Goalscorer wager as the betting odds look really appealing.

Latest Samuel Lino Player Prop Odds

Goalscorer

Anytime

+380

First

+800

Shots On Target

Over 0.5

-114

Under 0.5

-137

Shots

Over 1.5

-182

Under 1.5

-

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Estudiantes vs Flamengo Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

The bookies have Flamengo as +123 favourites for this Copa Libertadores clash, with the Full-Time Result betting odds implying that they are 45% likely to win. Estudiantes are the +245 underdogs, while the draw can also be backed as an alternative.

There are different ways to bet on Flamengo winning and that includes the -112 about them on the Asian Handicap -0.25. It also means that if they draw with Estudiantes, you get half stakes refunded.

A low-scoring contest will be predicted by several which is reflected in the fact that Under 2.5 Goals has the shortest odds. If you’re looking to wager Both Teams to Score No, this is currently available at -143.

The leading football betting sites have excellent coverage when it comes to all Copa Libertadores games. That means hundreds of markets from which to choose and something to suit everyone.

Full-Time Result

1

+245

X

+215

2

+123

Half-Time Result

1

+310

X

+105

2

+190

Double Chance

1X

-156

12

-286

X2

-333

Draw No Bet

1

+133

2

-185

Asian Handicap

1 Hcp +0.25

-110

2 Hcp -0.25

-112

Total Goals

Under 2.5

-179

Over 2.5

+143

Both Teams to Score

Yes

+102

No

-143

Those interested in Pedro Guilherme Abreu dos Santos to find the net anytime can get +165, with the favourite on offer to score the first goal at odds of +360.

Pedro Guilherme Abreu dos Santos (Flamengo)

First

+165

Anytime

+360

Giorgian de Arrascaeta (Flamengo)

First

+260

Anytime

+500

Guido Carrillo (Estudiantes)

First

+310

Anytime

+700

Luiz Araújo (Flamengo)

First

+370

Anytime

+750

Samuel Lino (Flamengo)

First

+380

Anytime

+800

Gonzalo Plata (Flamengo)

First

+410

Anytime

+850

Tiago Palacios (Estudiantes)

First

+500

Anytime

+1050

Edwuin Cetré (Estudiantes)

First

+550

Anytime

+1150

Santiago Ascacibar (Estudiantes)

First

+650

Anytime

+1300

Saúl Ñíguez (Flamengo)

First

+750

Anytime

+1400

Jorginho (Flamengo)

First

+850

Anytime

+1700

Nicolás de la Cruz (Flamengo)

First

+900

Anytime

+1800

Cristian Medina (Estudiantes)

First

+1000

Anytime

+2000

Guido Carrillo (Estudiantes)

Over 0.5

-167

Under 0.5

-100

Giorgian de Arrascaeta (Flamengo)

Over 0.5

-149

Under 0.5

-105

Luiz Araújo (Flamengo)

Over 0.5

-115

Under 0.5

-135

Samuel Lino (Flamengo)

Over 0.5

-114

Under 0.5

-137

Gonzalo Plata (Flamengo)

Over 0.5

-105

Under 0.5

-149

Tiago Palacios (Estudiantes)

Over 0.5

+105

Under 0.5

-164

Edwuin Cetré (Estudiantes)

Over 0.5

+117

Under 0.5

-185

Santiago Ascacibar (Estudiantes)

Over 0.5

+145

Under 0.5

-238

Pedro Guilherme Abreu dos Santos (Flamengo)

Over 1.5

+160

Under 1.5

-286

Saúl Ñíguez (Flamengo)

Over 0.5

+210

Under 0.5

-370

Cristian Medina (Estudiantes)

Over 0.5

+220

Under 0.5

-385

Jorginho (Flamengo)

Over 0.5

+260

Under 0.5

-500

Nicolás de la Cruz (Flamengo)

Over 0.5

+260

Under 0.5

-500

Pedro Guilherme Abreu dos Santos (Flamengo)

Over 3.5

+132

Under 3.5

-

Giorgian de Arrascaeta (Flamengo)

Over 2.5

+107

Under 2.5

-

Guido Carrillo (Estudiantes)

Over 2.5

-109

Under 2.5

-

Luiz Araújo (Flamengo)

Over 1.5

-172

Under 1.5

-

Samuel Lino (Flamengo)

Over 1.5

-182

Under 1.5

-

Tiago Palacios (Estudiantes)

Over 1.5

-149

Under 1.5

-

Edwuin Cetré (Estudiantes)

Over 1.5

-133

Under 1.5

-

Santiago Ascacibar (Estudiantes)

Over 1.5

+120

Under 1.5

-

Saúl Ñíguez (Flamengo)

Over 0.5

-217

Under 0.5

-

Cristian Medina (Estudiantes)

Over 0.5

-222

Under 0.5

-

Latest Copa Libertadores and domestic league stats. Full Time Result, Goals, Corners and Possession.

Estudiantes Stats

Flamengo Stats

Full-Time Result

• 5 wins and 5 defeats in the previous 10 matches
• 6 wins, 2 defeats and 2 draws in the previous 10 home matches

Full-Time Result

• 7 wins and 3 draws in the previous 10 matches
• 6 wins, 2 defeats and 2 draws in the previous 10 away matches

Goals

• An average of 1.00 goals scored and 1.20 conceded in the previous 10 matches
• An average of 1.20 goals scored and 0.80 conceded in the previous 10 home matches
• An average of 2.20 goals per game in the previous 10 matches
• An average of 2.00 goals per game in the previous 10 home matches
• BTTS Yes in 4 of the previous 10 matches
• BTTS Yes in 5 of the previous 10 home matches
• Over 2.5 Goals in 4 of the previous 10 matches
• Over 2.5 Goals in 4 of the previous 10 home matches

Goals

• An average of 2.20 goals scored and 0.60 conceded in the previous 10 matches
• An average of 1.50 goals scored and 0.70 conceded in the previous 10 away matches
• An average of 2.80 goals per game in the previous 10 matches
• An average of 2.20 goals per game in the previous 10 away matches
• BTTS Yes in 6 of the previous 10 matches
• BTTS Yes in 5 of the previous 10 away matches
• Over 2.5 Goals in 4 of the previous 10 matches
• Over 2.5 Goals in 4 of the previous 10 away matches

Corners

• An average of 4.70 corners awarded and 4.90 corners conceded in the last 10 matches
• An average of 6.00 corners awarded and 3.90 corners against in the last 10 home matches
• An average of 9.60 corners awarded in the last 10 matches
• An average of 9.90 corners awarded in the last 10 home matches
• Had the most corners in 6 and least corners in 3 of the last 10 matches
• Had the most corners in 9 and least corners in 0 of the last 10 home matches

Corners

• An average of 6.90 corners awarded and 4.90 corners conceded in the last 10 matches
• An average of 5.90 corners awarded and 4.00 corners against in the last 10 away matches
• An average of 11.80 corners awarded in the last 10 matches
• An average of 9.90 corners awarded in the last 10 away matches
• Had the most corners in 7 and least corners in 3 of the last 10 matches
• Had the most corners in 7 and least corners in 2 of the last 10 away matches

Possession

• An average of 55.20% possession in the last 10 matches
• An average of 61.40% possession in the last 10 home matches
• Most possession in 8 of the last 10 matches
• Most possession in 10 of the last 10 home matches

Possession

• An average of 64.00% possession in the last 10 matches
• An average of 63.60% possession in the last 10 away matches
• Most possession in 10 of the last 10 matches
• Most possession in 9 of the last 10 away matches

Estudiantes vs Flamengo Lineups & Team News

Check the Estudiantes vs Flamengo team news before you place your bets. Get the latest predicted and confirmed Copa Libertadores lineups and injury news right here.

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