Flamengo vs Estudiantes Prediction, Betting Tips, Lineups & Odds | 18 Sep 2025

Copa Libertadores Betting Preview: Flamengo vs Estudiantes

Brazilian Série A team Flamengo host Argentine Primera División outfit Estudiantes in the first leg of this Copa Libertadores quarter-final tie, with kick-off set for 21:30 on Thursday 18 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and confirmed lineups.

Side With Flamengo on the Asian Handicap

There’s a strong chance that Flamengo won’t just win the game but have a comfortable margin of victory against Estudiantes. We’re happy to wager the favourites -1.5 at odds of -106 on the Asian Handicap.

Confident in our Asian Handicap pick? Unlock the best BetMGM promo code and read our expert review of the site before jumping in.

Flamengo Landed Victory in Last Game

Flamengo got the win in their last game. A 2-0 Série A triumph occurred on their travels when meeting Juventude. The Scarlet-Black recorded a remarkable 75% of possession and managed two shots on target, with Giorgian De Arrascaeta and Emerson Royal scoring one goal apiece.

Estudiantes de La Plata were defeated in their previous game, losing 2-1 at home to River Plate in the Primera División. Eduardo Dominguez's team had the lion’s share of the ball recording 55% possession and two shots on goal, while Santiago Nunez found the net.

In the round of 16, Flamengo recorded a 3-0 aggregate victory against Brazilian Série A rivals Internacional, with Estudiantes progressing after a narrow 1-0 aggregate win over Paraguayan Primera División side Cerro Porteño.

Copa Libertadores		G	W	D	L	GF	GA	GD	GD	P
1	Estudiantes	6	4	0	2	11	5	6	11:5	12
2	Flamengo	6	3	2	1	6	3	3	6:3	11

View Full Table

Flamengo have 7 wins, 1 loss and 2 draws, averaging 2.1 goals from 5.3 shots on goal and 11.2 attempts. The Rio de Janeiro outfit have averaged 65.3% possession and 7.4 corners per match, with the opposition scoring 0.6 goals from 3.0 shots on goal, 7.0 attempts and 4.5 corners.

Pedro leads the way with 6 goals, Giorgian De Arrascaeta has 4, with Samuel Dias Lino and two others on 2. Giorgian De Arrascaeta is the top assists maker on 6.

Estudiantes have 4 victories and 6 defeats, with an average of 0.9 goals from 7.9 attempts and 3.7 shots on goal. Eduardo Dominguez's team average 53.5% possession, 4.3 corners in their favour and 4.8 corners against, while conceding 1.6 goals from 9.8 attempts and 4.7 shots on goal.

Leandro Gonzalez Pirez has scored 2 goals, followed by Santiago Nunez, Santiago Arzamendia, Roman Gomez and Fabricio Perez on 1. Look no further than Edwuin Cetre for the top assist maker (3) in the last 10 games.

Confirmed Lineups

Flamengo confirmed lineup (4-2-3-1): Agustin Rossi (GK), Guillermo Varela, Leo Ortiz, Leo Pereira, Ayrton Lucas, Nicolas de la Cruz, Saul Niguez, Gonzalo Plata, Giorgian De Arrascaeta, Samuel Dias Lino, Pedro.

Estudiantes confirmed lineup (4-2-3-1): Fernando Muslera (GK), Roman Gomez, Santiago Nunez, Facundo Rodriguez, Santiago Arzamendia, Ezequiel Piovi, Mikel Amondarain, Facundo Farias, Santiago Ascacibar, Cristian Medina, Guido Carrillo.

Flamengo vs Estudiantes Prediction & Betting Tips

Get ready for Flamengo vs Estudiantes with all the betting angles covered, from an expert match prediction and correct score advice to player props and a custom bet builder.

Match Prediction

We are not only backing Flamengo to win but taking them on the Asian Handicap in this Copa Libertadores game. The favourites can cover a -1.5 shortfall and the odds of -106 seem more than generous.

Plenty of research goes into our football picks. It begins by focusing on the latest Copa Libertadores form and knowing the injury situation. The important numbers can then be utilised to help complete the picture.

Key Flamengo vs Estudiantes Copa Libertadores & league stats:

• The -1.5 line has been covered by Flamengo in 4 of their last 5 games.

Flamengo -1.5 Probability

According to the top bookmakers, our pick has a 51.5% chance of landing a return. However, our tipsters in-depth research has found that the actual probability is between 55-60%. It’s the reason why we are recommending this bet.

Those wanting an alternative to Asian Handicap can consider Winning Margin where there are several options. Take a view on Flamengo and their performance.

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Our Match Prediction

Flamengo Asian Hcp -1.5 @ -106 Bet Now

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Correct Score Prediction

Flamengo 2 - 0 Estudiantes

Our correct score prediction is a 2-0 win for Flamengo which is available at odds of +375. We think they’ll achieve victory and this is a way of getting bigger odds and more excitement.

Player Prop Picks

Top Pick: Pedro Guilherme Abreu dos Santos Under 1.5 Shots On Target -154

Pedro Guilherme Abreu dos Santos (Flamengo) can be wagered at -154 to fail to cover the shots on goal total. We’ll take a chance with this Shots on Target pick as the betting odds look pretty attractive.

Latest Pedro Guilherme Abreu dos Santos Player Prop Odds

Goalscorer

Anytime

+125

First

+300

Shots On Target

Over 1.5

-102

Under 1.5

-167

Shots

Over 4.5

+132

Under 4.5

-

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Giorgian de Arrascaeta to Score +190

Giorgian de Arrascaeta (Flamengo) has scored in four straight games. There are odds of +190 available for this Anytime Goalscorer wager and we think this is a value proposition for the player to find the net.

Latest Giorgian de Arrascaeta Player Prop Odds

Goalscorer

Anytime

+170

First

+350

Shots On Target

Over 0.5

-137

Under 0.5

-112

Shots

Over 2.5

-128

Under 2.5

-

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Flamengo vs Estudiantes Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Flamengo Big Favourites on the Full-Time Result Market

Bettors might not get rich backing Flamengo at -313 to triumph in this Copa Libertadores clash although these odds suggest a 76% probability that the favourites end up triumphing. For those wanting to oppose the market leader, you can get +1100 about Estudiantes.

For those wanting an alternative, Flamengo are -112 on the Half-Time Result market. This means they need to lead at the break, with Estudiantes being priced up at +850 and the draw is +130.

Under 2.5 Goals is available as the favourite and a bet on this pick means that you don’t want more than two goals to be netted. A viable alternative is betting the BTTS market and opting for the -286 about Both Teams to Score No.

The top football betting sites cover Copa Libertadores matches in serious depth and there are hundreds of markets. We recommend scanning through the various bets before picking out the best angle.

Full-Time Result

1

-313

X

+380

2

+1100

Half-Time Result

1

-112

X

+130

2

+850

Double Chance

1X

-2000

12

-556

X2

+220

Draw No Bet

1

-1429

2

+600

Asian Handicap

1 Hcp -1.25

-125

2 Hcp +1.25

-100

Total Goals

Under 2.5

-159

Over 2.5

+128

Both Teams to Score

Yes

+195

No

-286

Pedro Guilherme Abreu dos Santos is the First Goalscorer Favourite

Pedro Guilherme Abreu dos Santos is favourite to be First Goalscorer at +300 and if you’re keen to back him to simply find the net, then the price is +125.

Pedro Guilherme Abreu dos Santos (Flamengo)

First

+125

Anytime

+300

Giorgian de Arrascaeta (Flamengo)

First

+170

Anytime

+350

Bruno Henrique Pinto (Flamengo)

First

+265

Anytime

+575

Samuel Lino (Flamengo)

First

+290

Anytime

+575

Gonzalo Plata (Flamengo)

First

+310

Anytime

+650

Saúl Ñíguez (Flamengo)

First

+500

Anytime

+1000

Nicolás de la Cruz (Flamengo)

First

+600

Anytime

+1200

Jorginho (Flamengo)

First

+600

Anytime

+1200

Guido Carrillo (Estudiantes)

First

+600

Anytime

+1300

Tiago Palacios (Estudiantes)

First

+1000

Anytime

+2000

Edwuin Cetré (Estudiantes)

First

+1100

Anytime

+2200

Leonardo Ortiz (Flamengo)

First

+1100

Anytime

+2200

Ayrton Lucas Dantas de Medeiros (Flamengo)

First

+1150

Anytime

+2200

Bruno Henrique Pinto (Flamengo)

Over 0.5

-175

Under 0.5

+102

Samuel Lino (Flamengo)

Over 0.5

-175

Under 0.5

+110

Gonzalo Plata (Flamengo)

Over 0.5

-139

Under 0.5

-112

Giorgian de Arrascaeta (Flamengo)

Over 0.5

-137

Under 0.5

-112

Pedro Guilherme Abreu dos Santos (Flamengo)

Over 1.5

-102

Under 1.5

-167

Guido Carrillo (Estudiantes)

Over 0.5

+108

Under 0.5

-185

Saúl Ñíguez (Flamengo)

Over 0.5

+145

Under 0.5

-238

Tiago Palacios (Estudiantes)

Over 0.5

+160

Under 0.5

-270

Nicolás de la Cruz (Flamengo)

Over 0.5

+170

Under 0.5

-294

Edwuin Cetré (Estudiantes)

Over 0.5

+175

Under 0.5

-303

Jorginho (Flamengo)

Over 0.5

+190

Under 0.5

-333

Ayrton Lucas Dantas de Medeiros (Flamengo)

Over 0.5

+350

Under 0.5

-833

Leonardo Ortiz (Flamengo)

Over 0.5

+370

Under 0.5

-833

Pedro Guilherme Abreu dos Santos (Flamengo)

Over 4.5

+132

Under 4.5

-

Giorgian de Arrascaeta (Flamengo)

Over 2.5

-128

Under 2.5

-

Bruno Henrique Pinto (Flamengo)

Over 2.5

-119

Under 2.5

-

Samuel Lino (Flamengo)

Over 2.5

-125

Under 2.5

-

Gonzalo Plata (Flamengo)

Over 2.5

+125

Under 2.5

-

Saúl Ñíguez (Flamengo)

Over 1.5

+105

Under 1.5

-

Nicolás de la Cruz (Flamengo)

Over 1.5

+132

Under 1.5

-

Guido Carrillo (Estudiantes)

Over 1.5

-102

Under 1.5

-

Tiago Palacios (Estudiantes)

Over 1.5

+160

Under 1.5

-

Edwuin Cetré (Estudiantes)

Over 0.5

-233

Under 0.5

-

Ayrton Lucas Dantas de Medeiros (Flamengo)

Over 0.5

-154

Under 0.5

-

Latest Copa Libertadores and domestic league stats. Full Time Result, Goals, Corners and Possession.

Flamengo Stats

Estudiantes Stats

Full-Time Result

• 7 wins, 1 defeat and 2 draws in the previous 10 matches
• 8 wins and 2 draws in the previous 10 home matches

Full-Time Result

• 4 wins and 6 defeats in the previous 10 matches
• 1 win, 8 defeats and 1 draw in the previous 10 away matches

Goals

• An average of 2.10 goals scored and 0.60 conceded in the previous 10 matches
• An average of 2.50 goals scored and 0.20 conceded in the previous 10 home matches
• An average of 2.70 goals per game in the previous 10 matches
• An average of 2.70 goals per game in the previous 10 home matches
• BTTS Yes in 5 of the previous 10 matches
• BTTS Yes in 2 of the previous 10 home matches
• Over 2.5 Goals in 4 of the previous 10 matches
• Over 2.5 Goals in 4 of the previous 10 home matches

Goals

• An average of 0.90 goals scored and 1.60 conceded in the previous 10 matches
• An average of 0.50 goals scored and 1.80 conceded in the previous 10 away matches
• An average of 2.50 goals per game in the previous 10 matches
• An average of 2.30 goals per game in the previous 10 away matches
• BTTS Yes in 4 of the previous 10 matches
• BTTS Yes in 3 of the previous 10 away matches
• Over 2.5 Goals in 5 of the previous 10 matches
• Over 2.5 Goals in 3 of the previous 10 away matches

Corners

• An average of 7.40 corners awarded and 4.50 corners conceded in the last 10 matches
• An average of 7.80 corners awarded and 3.40 corners against in the last 10 home matches
• An average of 11.90 corners awarded in the last 10 matches
• An average of 11.20 corners awarded in the last 10 home matches
• Had the most corners in 8 and least corners in 2 of the last 10 matches
• Had the most corners in 8 and least corners in 2 of the last 10 home matches

Corners

• An average of 4.30 corners awarded and 4.80 corners conceded in the last 10 matches
• An average of 3.30 corners awarded and 4.80 corners against in the last 10 away matches
• An average of 9.10 corners awarded in the last 10 matches
• An average of 8.10 corners awarded in the last 10 away matches
• Had the most corners in 5 and least corners in 4 of the last 10 matches
• Had the most corners in 2 and least corners in 7 of the last 10 away matches

Possession

• An average of 65.30% possession in the last 10 matches
• An average of 61.80% possession in the last 10 home matches
• Most possession in 10 of the last 10 matches
• Most possession in 10 of the last 10 home matches

Possession

• An average of 53.50% possession in the last 10 matches
• An average of 53.90% possession in the last 10 away matches
• Most possession in 7 of the last 10 matches
• Most possession in 7 of the last 10 away matches

Flamengo vs Estudiantes Lineups & Team News

Double-check the Flamengo vs Estudiantes team news before placing your bets. We’ll deliver the predicted and confirmed Copa Libertadores lineups as well as the most recent injury news.