Independiente vs Universidad de Chile Prediction, Betting Tips, Lineups & Odds | 20 Aug 2025
Copa Sudamericana Betting Preview: Independiente vs Universidad de Chile
Argentine Primera División side Independiente host Chilean Primera División team Universidad de Chile in the second leg of this Copa Sudamericana round of 16 tie, with kick-off set for 20:30 on Wednesday 20 August 2025. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and confirmed lineups.
Independiente Value to Beat La U
We’re confident in the chances of Independiente when they clash with Universidad de Chile, with our selection appealing on the Full-Time Result market. Take the odds of -152 that the favourites claim a victory.
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First Leg Saw 1-0 La U Win
Independiente were beaten last game and this was away from home. Vélez Sarsfield claimed a 2-1 Argentine Primera División win. Julio Vaccari's men recorded 43% possession and had three shots on target, with Felipe Loyola scoring the goal.
Universidad de Chile lost their previous game, being beaten at home to Audax Italiano 3-1 in the Chilean Primera División. La U enjoyed 65% possession and managed four shots on goal, with Lucas Di Yorio finding the net.
Head-to-Head Statistics
U. de Chile beat Independiente 1-0 at home in the first leg, with Lucas Assadi scoring the winner. The hosts had 54% possession, while shots on target were level at 4-4.
Independiente – Last 10 League & Copa Sudamericana Games2 wins, 6 losses and 2 draws, averaging 1.1 goals from 3.6 shots on goal and 8.6 attempts. Independiente have had 60.0% possession and 4.1 corners per game. On average, they have conceded 1.6 goals from 3.5 shots on goal and 7.3 attempts, while their opponents have been awarded 4.5 corners.
Top goalscorer Felipe Loyola has found the net 2 times, with Nicolas Freire, Gabriel Avalos, Alvaro Angulo and Santiago Gabriel Montiel scoring 1 each. The top assist makers are Santiago Gabriel Montiel, Leonardo Godoy and Federico Mancuello, all of whom have 1 on the board.
Universidad de Chile – Last 10 League & Copa Sudamericana GamesU. de Chile have won 6, lost 3 and drawn 1, averaging 5.6 shots on goal, 12.6 attempts and 2.4 goals. Gustavo Alvarez's team average 59.0% possession, 4.7 corners taken and 2.8 corners against them, while 1.0 goals have been conceded from 6.8 attempts and 3.7 shots on goal.
Lucas Di Yorio and Lucas Assadi have top scored with 4 goals, while Rodrigo Contreras is next on 3. Lucas Assadi has managed 5 assists in the last 10 games.
Independiente vs Universidad de Chile Prediction & Betting Tips
Get the edge with our Independiente vs Universidad de Chile betting tips: our expert match prediction, most likely correct score outcome and a bet builder tailored for value.
Match Prediction
We’ll take Independiente at attractive betting odds of -152 considering that they could be dominant in this Copa Sudamericana game. This match winner wager provides plenty of value and a nice potential return.
The first step involves analysing the form and also getting an idea of the injury situation before making any football picks. Then it’s a case of consulting the latest Copa Sudamericana stats and seeing if they can inform our opinion.
Key Independiente vs Universidad de Chile Copa Sudamericana & league stats:
Independiente to Win Probability
According to the top bookmakers, our pick has a 60.2% chance of landing a return. In the opinion of our tipsters, there’s actually a probability of success closer to 70%. This is why we can recommend this bet.
Those looking for tastier odds about a win for Independiente can take a look at the Match Result & Total market. You can combine your match winner pick with an Under / Over goals prediction for more juice.
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Correct Score Prediction
We’re going for Independiente at +575 to secure a 2-0 win. It’s exciting to bet on the correct score and this wager will hopefully be able to land a nice return.
Bet Builder Tips
A bet builder always adds excitement and the picks are Independiente to triumph, less than three goals to be registered together with BTTS No.
A bet builder provides an exciting opportunity to follow various picks for the same football match. You can forecast specific things to happen and enjoy larger odds compared to betting a single. The odds multiply for each leg.
Independiente vs Universidad de Chile Odds
The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.
Independiente Have the Shortest Odds to Win
The Independiente betting odds are -156 which means that they’re favourites to land victory in this Copa Sudamericana encounter. It’s also suggested by the bookies that this team have a 61% chance of winning. Universidad de Chile are an outside chance to get the job done and you can now back them at +400.
Independiente -0.75 on the Asian Handicap is available at -125 and means a full payout if they win by two or more against U. de Chile. A victory by one goal means half the stake wins and the other half is refunded.
For those expecting a low-scoring contest, Under 2.5 is the market leader on the Total Goals market. A fresh approach might involve siding with a BTTS wager and there’s -149 on offer for Both Teams to Score No.
The top football betting sites provide hundreds of markets for the latest Copa Sudamericana matches. Be sure to peruse all of the available options before going ahead with your preferred wager.















Latest Copa Sudamericana and domestic league stats. Full Time Result, Goals, Corners and Possession.


- 2 wins, 6 defeats and 2 draws in the previous 10 matches
- 5 wins, 2 defeats and 3 draws in the previous 10 home matches
- 6 wins, 3 defeats and 1 draw in the previous 10 matches
- 4 wins, 4 defeats and 2 draws in the previous 10 away matches
- An average of 1.10 goals scored and 1.60 conceded in the previous 10 matches
- An average of 1.90 goals scored and 0.90 conceded in the previous 10 home matches
- An average of 2.70 goals per game in the previous 10 matches
- An average of 2.80 goals per game in the previous 10 home matches
- BTTS Yes in 3 of the previous 10 matches
- BTTS Yes in 2 of the previous 10 home matches
- Over 2.5 Goals in 3 of the previous 10 matches
- Over 2.5 Goals in 3 of the previous 10 home matches
- An average of 2.40 goals scored and 1.00 conceded in the previous 10 matches
- An average of 1.70 goals scored and 1.30 conceded in the previous 10 away matches
- An average of 3.40 goals per game in the previous 10 matches
- An average of 3.00 goals per game in the previous 10 away matches
- BTTS Yes in 5 of the previous 10 matches
- BTTS Yes in 5 of the previous 10 away matches
- Over 2.5 Goals in 7 of the previous 10 matches
- Over 2.5 Goals in 5 of the previous 10 away matches
- An average of 4.10 corners awarded and 4.50 corners conceded in the last 10 matches
- An average of 5.10 corners awarded and 3.90 corners against in the last 10 home matches
- An average of 8.60 corners awarded in the last 10 matches
- An average of 9.00 corners awarded in the last 10 home matches
- Had the most corners in 4 and least corners in 4 of the last 10 matches
- Had the most corners in 6 and least corners in 3 of the last 10 home matches
- An average of 4.70 corners awarded and 2.80 corners conceded in the last 10 matches
- An average of 5.40 corners awarded and 2.70 corners against in the last 10 away matches
- An average of 7.50 corners awarded in the last 10 matches
- An average of 8.10 corners awarded in the last 10 away matches
- Had the most corners in 6 and least corners in 4 of the last 10 matches
- Had the most corners in 8 and least corners in 2 of the last 10 away matches
- An average of 60.00% possession in the last 10 matches
- An average of 61.00% possession in the last 10 home matches
- Most possession in 9 of the last 10 matches
- Most possession in 10 of the last 10 home matches
Independiente vs Universidad de Chile Lineups & Team News
Always review the Independiente vs U. de Chile team news before locking in your bets. Get the latest predicted and confirmed Copa Sudamericana lineups and injury news right here.
Previous Independiente Lineups
Previous Universidad de Chile Lineups
# | Team | G | W | D | L | +/- | P |
---|---|---|---|---|---|---|---|
1 | Independiente | 6 | 4 | 0 | 2 | 16:6 | 12 |
2 | Club Guarani | 6 | 2 | 2 | 2 | 9:12 | 8 |
3 | Boston River | 6 | 2 | 1 | 3 | 12:14 | 7 |
4 | Nacional Potosi | 6 | 2 | 1 | 3 | 8:13 | 7 |
# | Team | G | W | D | L | +/- | P |
---|---|---|---|---|---|---|---|
1 | Universidad Catolica | 6 | 4 | 2 | 0 | 12:5 | 14 |
2 | Cerro Largo | 6 | 2 | 1 | 3 | 5:8 | 7 |
3 | Vitória | 6 | 1 | 3 | 2 | 3:4 | 6 |
4 | Defensa Justicia | 6 | 0 | 4 | 2 | 4:7 | 4 |
# | Team | G | W | D | L | +/- | P |
---|---|---|---|---|---|---|---|
1 | Huracán | 6 | 4 | 2 | 0 | 11:2 | 14 |
2 | América de Cali | 6 | 1 | 5 | 0 | 6:4 | 8 |
3 | Corinthians | 6 | 2 | 2 | 2 | 5:5 | 8 |
4 | Racing | 6 | 0 | 1 | 5 | 3:14 | 1 |
# | Team | G | W | D | L | +/- | P |
---|---|---|---|---|---|---|---|
1 | Godoy Cruz | 6 | 3 | 3 | 0 | 10:5 | 12 |
2 | Grêmio | 6 | 3 | 3 | 0 | 8:4 | 12 |
3 | Atlético Grau | 6 | 0 | 4 | 2 | 5:9 | 4 |
4 | Luqueno | 6 | 0 | 2 | 4 | 4:9 | 2 |
# | Team | G | W | D | L | +/- | P |
---|---|---|---|---|---|---|---|
1 | Mushuc Runa | 6 | 5 | 1 | 0 | 12:4 | 16 |
2 | Palestino | 6 | 3 | 0 | 3 | 9:9 | 9 |
3 | Cruzeiro | 6 | 1 | 2 | 3 | 5:7 | 5 |
4 | Unión | 6 | 1 | 1 | 4 | 2:8 | 4 |
# | Team | G | W | D | L | +/- | P |
---|---|---|---|---|---|---|---|
1 | Fluminense | 6 | 4 | 1 | 1 | 11:2 | 13 |
2 | Once Caldas | 6 | 4 | 0 | 2 | 8:6 | 12 |
3 | Unión Española | 6 | 1 | 2 | 3 | 6:7 | 5 |
4 | GV San Jose | 6 | 1 | 1 | 4 | 5:15 | 4 |
# | Team | G | W | D | L | +/- | P |
---|---|---|---|---|---|---|---|
1 | Lanús | 6 | 3 | 3 | 0 | 9:4 | 12 |
2 | Vasco da Gama | 6 | 2 | 2 | 2 | 8:8 | 8 |
3 | Melgar | 6 | 2 | 1 | 3 | 5:10 | 7 |
4 | Academia Puerto Cabello | 6 | 1 | 2 | 3 | 8:8 | 5 |
# | Team | G | W | D | L | +/- | P |
---|---|---|---|---|---|---|---|
1 | Cienciano | 6 | 2 | 4 | 0 | 12:6 | 10 |
2 | Atlético MG | 6 | 2 | 3 | 1 | 11:6 | 9 |
3 | Caracas | 6 | 2 | 2 | 2 | 9:11 | 8 |
4 | Iquique | 6 | 1 | 1 | 4 | 7:16 | 4 |

















