Inter Milan vs Sassuolo Prediction, Betting Tips, Lineups & Odds | 21 Sep 2025

Serie A Betting Preview: Inter Milan vs Sassuolo

Inter Milan host Sassuolo in this Italian Serie A meeting at Giuseppe Meazza, with kick-off set for 14:45 on Sunday 21 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

BTTS Yes Looks the Value Bet

The stats suggest that we’ll see both teams finding the net, with Inter and Sassuolo capable of scoring. We find the odds of +102 attractive when it comes to the BTTS Yes option.

Like this BTTS Yes bet? Use the new BetMGM promo code and see what our experts think of the platform in our in-depth review before getting in on the action.

Sassuolo 1-0 Winners When Teams Last Met

Inter Milan have been defeated in back-to-back Serie A games. On the road, they recently suffered a 4-3 loss against Juventus at Allianz Stadium. I Nerazzurri had four shots on target and boasted 59% possession, with Hakan Calhanoglu bagging two goals and Marcus Thuram scoring the other.

On Wednesday night, Inter visited Ajax in the Champions League and won 2-0.

Sassuolo won their previous game, beating Lazio at home. It was a 1-0 victory at Stadio Mapei. The Emilia-Romagna side recorded three shots on goal and had 41% possession, with Alieu Fadera on target in the 70th minute.

Head-to-Head Statistics

Sassuolo have triumphed in the last two encounters against Inter. There was a 1-0 home triumph at Stadio Mapei after winning 2-1 away at Giuseppe Meazza. The past 10 H2H matches have seen Inter triumph six times, one draw and three Sassuolo wins.

Serie A		G	W	D	L	GF	GA	GD	GD	P
11	Inter Milan	3	1	0	2	9	6	3	9:6	3
14	Sassuolo	3	1	0	2	3	5	-2	3:5	3

View Full Table

5 wins, 4 losses and 1 draw, averaging 1.9 goals from 4.3 shots on goal and 13.1 attempts. Inter have had 61.1% possession, 565.8 passes and 5.9 corners per game. On average, they have conceded 1.1 goals from 3.9 shots on goal and 12.5 attempts, while their opponents have been awarded 4.0 corners.

Top goalscorer Marcus Thuram has found the net 3 times, with Hakan Calhanoglu, Denzel Dumfries, Lautaro Martinez and Yann Aurel Bisseck scoring 2 each. Federico Dimarco, Carlos Augusto and Alessandro Bastoni are tied for the most assists on 2, with goalie Yann Sommer managing 2 clean sheets.

Sassuolo have won 4, lost 5 and drawn 1, with an average of 4.7 shots on goal, 9.8 attempts and 1.4 goals. The Emilia-Romagna outfit average 48.8% possession, 4.1 corners awarded and 5.5 corners against, while 1.5 goals have been conceded from 11.2 attempts and 5.2 shots on goal.

Armand Lauriente is top of the team’s scoring charts with 4, while Domenico Berardi and Luca Moro have 2. Tarik Muharemovic and Cristian Volpato have managed 2 assists in the last 10 games, while Arijanet Muric has one clean sheet to his name.

Predicted & Confirmed Lineups

Inter Milan predicted lineup (3-5-2): Josep Martinez (GK), Yann Aurel Bisseck, Francesco Acerbi, Alessandro Bastoni, Denzel Dumfries, Nicolò Barella, Hakan Calhanoglu, Petar Sucic, Federico Dimarco, Marcus Thuram, Lautaro Martinez.

Sassuolo predicted lineup (4-3-3): Arijanet Muric (GK), Woyo Coulibaly, Jay Idzes, Tarik Muharemovic, Josh Doig, Ismaël Koné, Nemanja Matic, Aster Vranckx, Domenico Berardi, Andrea Pinamonti, Armand Lauriente.

Inter Milan vs Sassuolo Prediction & Betting Tips

Get the edge with our best Inter Milan vs Sassuolo tips: a key match prediction, expert corners pick, correct score recommendation, top player prop bets and a ready-made bet builder.

Match Prediction

There’s every reason to wager on both teams finding the net, with the BTTS Yes selection attractively priced for this Serie A encounter. You can land +102 that both teams score a goal.

Our football betting tips are provided off the back of having access to the very latest team news. We also think it’s vital to study the form guide and delve into the most pertinent Serie A stats before coming up with a verdict.

Key Inter Milan vs Sassuolo league stats:

• BTTS Yes has been covered in 13 of the last 20 Inter games at home.
• BTTS Yes has been covered in 3 of the last 5 Inter games.
• BTTS Yes has been covered in 2 straight Inter games.

BTTS Yes Probability

According to the latest odds, our pick has a 49.5% chance of winning. In our opinion, there’s actually a probability of success between 55-60%. That means we’re regarding it as a value bet.

An alternative to BTTS Yes is going for Over 2.5 Goals to be scored. With this bet, it doesn’t matter which team scores providing that there are at least three goals in total.

Get more from your bets with our detailed guide, featuring the best free bets and generous welcome bonuses.

Our Match Prediction

Both Teams To Score - Yes @ +102 Watch Live Bet Now

BetMGM Promo Up To $1500 in Bonus Bets Get Bonus T&C apply. Gamble responsibly 18+

Gamble responsibly 18+. All odds are correct at time of publishing and are subject to change. To use the Bookmaker Live Streaming services you will need to be logged in and have a funded account or to have placed a bet in the last 24 hours. Geo-restrictions apply.

Correct Score Prediction

Inter 2 - 1 Sassuolo

Let’s take a chance on the +750 available that Inter secure a 2-1 victory. There’s a nice potential return waiting if we’re able to predict the correct score.

Player Prop Picks

Top Pick: Denzel Dumfries Over 0.5 Shots On Target +110

Denzel Dumfries (Inter) has finished with at least one shot on goal in six straight Serie A home games. In our opinion, there is value when it comes to him covering the Shots on Target line, with betting odds of +110 now available.

Latest Denzel Dumfries Player Prop Odds

Goalscorer

Anytime

+370

First

+950

Shots On Target

Over 0.5

+110

Under 0.5

-175

Shots

Over 1.5

-100

Under 1.5

-

T&C apply. Gamble responsibly 18+

---

Marcus Thuram to Score +135

Marcus Thuram (Inter) has scored three goals in his past five Serie A games. This data directs us to the Anytime Goalscorer market where we can bet him to find the net at attractive odds of +135.

Latest Marcus Thuram Player Prop Odds

Goalscorer

Anytime

+135

First

+370

Shots On Target

Over 1.5

+125

Under 1.5

-200

Shots

Over 3.5

-100

Under 3.5

-

T&C apply. Gamble responsibly 18+

Corners Prediction

Sassuolo Over 2.5 Corners -138

Sassuolo have had a corner average of 4.80 in the past five games, while Inter have let the opposition average 4.00 corners in their previous ten matches. There’s a chance to go over the Sassuolo Team Corners line and we’re confident this will happen, with odds of -138 on offer.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Inter

Total

9.90 5.90 4.00

Home

9.90 6.60 3.30

Away

11.10 5.90 5.20

Sassuolo

Total

9.60 4.10 5.50

Home

8.80 4.70 4.10

Away

8.60 3.30 5.30

Latest Corner Odds

Total Corners

Over 9.5

-110

Under 9.5

-128

Inter Corners

Over 6.5

-120

Under 6.5

-120

Sassuolo Corners

Over 2.5

-138

Under 2.5

-100

Most Corners

1

-455

X

+850

2

+450

T&C apply. Gamble responsibly 18+

Inter Milan vs Sassuolo Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Inter Heavy Favourites With the Betting Sites

The Full-Time Result odds suggest that Inter Milan have a 80% prospect of triumphing which results in the fact that they’re strong -400 favourites to win this Serie A encounter. Sassuolo are the +950 outsiders, with the draw being a different option which could yield dividends.

Inter -1.75 on the Asian Handicap at -102 would mean a full payout if they are able to beat Sassuolo by 3+ goals. A two-goal victory means half your stake wins and the other half is refunded.

The Total Goals market reveals that Over 2.5 Goals is the current betting favourite. The Both Teams to Score No option is -137 if you think at least one side will fail to score.

You can find hundreds of markets for every Serie A match, with the top betting apps creating lots of different options. Check out the pre-game and In-Play selections before placing your football bets.

Full-Time Result

1

-400

X

+480

2

+950

Half-Time Result

1

-141

X

+175

2

+650

Double Chance

1X

-2500

12

-769

X2

+255

Draw No Bet

1

-1429

2

+600

Asian Handicap

1 Hcp -1.75

-102

2 Hcp +1.75

-122

Total Goals

Under 2.5

+138

Over 2.5

-182

Both Teams to Score

Yes

+102

No

-137

Lautaro Martínez Top of First Goalscorer List

Favourite Lautaro Martínez is available at +225 to be the First Goalscorer. Similar odds apply if you’re interested in him to score the last goal.

Lautaro Martínez (Inter)

First

-147

Anytime

+225

Marcus Thuram (Inter)

First

+135

Anytime

+370

Ange-Yoan Bonny (Inter)

First

+225

Anytime

+500

Hakan Çalhanoglu (Inter)

First

+300

Anytime

+800

Federico Dimarco (Inter)

First

+350

Anytime

+950

Andy Diouf (Inter)

First

+370

Anytime

+900

Denzel Dumfries (Inter)

First

+370

Anytime

+950

Andrea Pinamonti (Sassuolo)

First

+390

Anytime

+1000

Henrikh Mkhitaryan (Inter)

First

+410

Anytime

+1150

Domenico Berardi (Sassuolo)

First

+420

Anytime

+1100

Armand Laurienté (Sassuolo)

First

+450

Anytime

+1100

Nicolò Barella (Inter)

First

+450

Anytime

+1200

Nicholas Pierini (Sassuolo)

First

+510

Anytime

+1300

Kristian Thorstvedt (Sassuolo)

First

+600

Anytime

+1500

Petar Sucic (Inter)

First

+650

Anytime

+1700

Stefan de Vrij (Inter)

First

+850

Anytime

+2200

Ange-Yoan Bonny (Inter)

Over 0.5

-175

Under 0.5

+110

Lautaro Martínez (Inter)

Over 1.5

-141

Under 1.5

-111

Federico Dimarco (Inter)

Over 0.5

-118

Under 0.5

-133

Hakan Çalhanoglu (Inter)

Over 0.5

-105

Under 0.5

-147

Andrea Pinamonti (Sassuolo)

Over 0.5

-100

Under 0.5

-159

Denzel Dumfries (Inter)

Over 0.5

+110

Under 0.5

-175

Domenico Berardi (Sassuolo)

Over 0.5

+110

Under 0.5

-175

Armand Laurienté (Sassuolo)

Over 0.5

+120

Under 0.5

-192

Marcus Thuram (Inter)

Over 1.5

+125

Under 1.5

-200

Andy Diouf (Inter)

Over 0.5

+125

Under 0.5

-200

Nicholas Pierini (Sassuolo)

Over 0.5

+135

Under 0.5

-222

Henrikh Mkhitaryan (Inter)

Over 0.5

+143

Under 0.5

-233

Nicolò Barella (Inter)

Over 0.5

+160

Under 0.5

-270

Kristian Thorstvedt (Sassuolo)

Over 0.5

+175

Under 0.5

-303

Petar Sucic (Inter)

Over 0.5

+230

Under 0.5

-417

Stefan de Vrij (Inter)

Over 0.5

+320

Under 0.5

-714

Lautaro Martínez (Inter)

Over 4.5

-115

Under 4.5

-

Marcus Thuram (Inter)

Over 3.5

-100

Under 3.5

-

Ange-Yoan Bonny (Inter)

Over 2.5

-104

Under 2.5

-

Hakan Çalhanoglu (Inter)

Over 1.5

-125

Under 1.5

-

Federico Dimarco (Inter)

Over 1.5

-147

Under 1.5

-

Andy Diouf (Inter)

Over 1.5

+120

Under 1.5

-

Denzel Dumfries (Inter)

Over 1.5

-100

Under 1.5

-

Andrea Pinamonti (Sassuolo)

Over 1.5

-147

Under 1.5

-

Henrikh Mkhitaryan (Inter)

Over 1.5

+128

Under 1.5

-

Domenico Berardi (Sassuolo)

Over 1.5

-135

Under 1.5

-

Armand Laurienté (Sassuolo)

Over 1.5

-118

Under 1.5

-

Nicolò Barella (Inter)

Over 1.5

+143

Under 1.5

-

Nicholas Pierini (Sassuolo)

Over 1.5

+115

Under 1.5

-

Kristian Thorstvedt (Sassuolo)

Over 1.5

+155

Under 1.5

-

Six Inter Wins From Their Past Ten Home Matches

Inter have six victories, two draws and two defeats in the last 10 home matches, netting an average of 2.10 goals per game and conceding 1.30.

Sassuolo have secured five victories, three defeats and two draws in the previous 10 away games, netting an average of 1.90 goals per match and conceding 1.40.

The previous Giuseppe Meazza encounter involved a 2-1 Sassuolo win against Inter. The past 6 H2H meetings at Giuseppe Meazza have involved two wins each and two draws.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Inter Milan Home Stats		6-2-2	3.40	2.10	1.30	8	2	7	3
Sassuolo Away Stats		5-2-3	3.30	1.90	1.40	7	3	7	3

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

Enjoy Serie A live streaming on your mobile, laptop or tablet. It’s great to watch the latest games through your online sportsbook account, with customers able to access high definition streams.

It’s great to enjoy thousands of sporting events on an annual basis. Watch the action and get audio commentary too.

Inter Milan vs Sassuolo Live Streaming Watch Live Geo-restrictions apply. To use the services you need to be logged in, a funded account or to have placed a bet in the last 24 hours.

Inter Milan vs Sassuolo Lineups & Team News

Before making your bets, take a look at the Inter vs Sassuolo team news. We’ll have the predicted and confirmed Serie A lineups for you plus all the latest on player injuries.

Inter Milan Team Page Sassuolo Team Page