Inter Milan vs Sassuolo Prediction, Betting Tips, Lineups & Odds | 21 Sep 2025

Serie A Betting Preview: Inter Milan vs Sassuolo

Inter Milan host Sassuolo in this Italian Serie A meeting at Giuseppe Meazza, with kick-off set for 14:45 on Sunday 21 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

BTTS Yes Looks the Value Bet

The stats suggest that we’ll see both teams finding the net, with Inter and Sassuolo capable of scoring. We find the odds of +102 attractive when it comes to the BTTS Yes option.

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Sassuolo 1-0 Winners When Teams Last Met

Inter Milan have been defeated in back-to-back Serie A games. On the road, they recently suffered a 4-3 loss against Juventus at Allianz Stadium. I Nerazzurri had four shots on target and boasted 59% possession, with Hakan Calhanoglu bagging two goals and Marcus Thuram scoring the other.

On Wednesday night, Inter visited Ajax in the Champions League and won 2-0.

Sassuolo won their previous game, beating Lazio at home. It was a 1-0 victory at Stadio Mapei. The Emilia-Romagna side recorded three shots on goal and had 41% possession, with Alieu Fadera on target in the 70th minute.

Head-to-Head Statistics

Sassuolo have triumphed in the last two encounters against Inter. There was a 1-0 home triumph at Stadio Mapei after winning 2-1 away at Giuseppe Meazza. The past 10 H2H matches have seen Inter triumph six times, one draw and three Sassuolo wins.

Serie A		G	W	D	L	GF	GA	GD	GD	P
2	Inter Milan	10	7	0	3	24	12	12	24:12	21
12	Sassuolo	10	4	1	5	11	12	-1	11:12	13

View Full Table

5 wins, 4 losses and 1 draw, averaging 1.9 goals from 4.3 shots on goal and 13.1 attempts. Inter have had 61.1% possession, 565.8 passes and 5.9 corners per game. On average, they have conceded 1.1 goals from 3.9 shots on goal and 12.5 attempts, while their opponents have been awarded 4.0 corners.

Top goalscorer Marcus Thuram has found the net 3 times, with Hakan Calhanoglu, Denzel Dumfries, Lautaro Martinez and Yann Aurel Bisseck scoring 2 each. Federico Dimarco, Carlos Augusto and Alessandro Bastoni are tied for the most assists on 2, with goalie Yann Sommer managing 2 clean sheets.

Sassuolo have won 4, lost 5 and drawn 1, with an average of 4.7 shots on goal, 9.8 attempts and 1.4 goals. The Emilia-Romagna outfit average 48.8% possession, 4.1 corners awarded and 5.5 corners against, while 1.5 goals have been conceded from 11.2 attempts and 5.2 shots on goal.

Armand Lauriente is top of the team’s scoring charts with 4, while Domenico Berardi and Luca Moro have 2. Tarik Muharemovic and Cristian Volpato have managed 2 assists in the last 10 games, while Arijanet Muric has one clean sheet to his name.

Confirmed Lineups

Inter Milan confirmed lineup (3-5-2): Josep Martinez (GK), Manuel Akanji, Francesco Acerbi, Carlos Augusto, Denzel Dumfries, Nicolo Barella, Hakan Calhanoglu, Petar Sucic, Federico Dimarco, Marcus Thuram, Francesco Pio Esposito.

Sassuolo confirmed lineup (4-3-3): Arijanet Muric (GK), Woyo Coulibaly, Jay Idzes, Tarik Muharemovic, Josh Doig, Aster Vranckx, Nemanja Matic, Ismael Kone, Domenico Berardi, Andrea Pinamonti, Armand Lauriente.

Inter Milan vs Sassuolo Prediction & Betting Tips

Get the edge with our best Inter Milan vs Sassuolo tips: a key match prediction, expert corners pick, correct score recommendation, top player prop bets and a ready-made bet builder.

Match Prediction

There’s every reason to wager on both teams finding the net, with the BTTS Yes selection attractively priced for this Serie A encounter. You can land +102 that both teams score a goal.

Our football betting tips are provided off the back of having access to the very latest team news. We also think it’s vital to study the form guide and delve into the most pertinent Serie A stats before coming up with a verdict.

Key Inter Milan vs Sassuolo league stats:

• BTTS Yes has been covered in 13 of the last 20 Inter games at home.
• BTTS Yes has been covered in 3 of the last 5 Inter games.
• BTTS Yes has been covered in 2 straight Inter games.

BTTS Yes Probability

According to the latest odds, our pick has a 49.5% chance of winning. In our opinion, there’s actually a probability of success between 55-60%. That means we’re regarding it as a value bet.

An alternative to BTTS Yes is going for Over 2.5 Goals to be scored. With this bet, it doesn’t matter which team scores providing that there are at least three goals in total.

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Our Match Prediction

Both Teams To Score - Yes @ +102 Bet Now

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Correct Score Prediction

Inter 2 - 1 Sassuolo

Let’s take a chance on the +750 available that Inter secure a 2-1 victory. There’s a nice potential return waiting if we’re able to predict the correct score.

Player Prop Picks

Top Pick: Denzel Dumfries Over 0.5 Shots On Target +110

Denzel Dumfries (Inter) has finished with at least one shot on goal in six straight Serie A home games. In our opinion, there is value when it comes to him covering the Shots on Target line, with betting odds of +110 now available.

Latest Denzel Dumfries Player Prop Odds

Goalscorer

Anytime

+360

First

+1000

Shots On Target

Over 0.5

+107

Under 0.5

-164

Shots

Over 1.5

-135

Under 1.5

-

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Marcus Thuram to Score +135

Marcus Thuram (Inter) has scored three goals in his past five Serie A games. This data directs us to the Anytime Goalscorer market where we can bet him to find the net at attractive odds of +135.

Latest Marcus Thuram Player Prop Odds

Goalscorer

Anytime

+102

First

+320

Shots On Target

Over 1.5

-115

Under 1.5

-135

Shots

Over 3.5

-130

Under 3.5

-

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Corners Prediction

Sassuolo Over 2.5 Corners -138

Sassuolo have had a corner average of 4.80 in the past five games, while Inter have let the opposition average 4.00 corners in their previous ten matches. There’s a chance to go over the Sassuolo Team Corners line and we’re confident this will happen, with odds of -138 on offer.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Inter

Total

9.90 5.90 4.00

Home

9.90 6.60 3.30

Away

11.10 5.90 5.20

Sassuolo

Total

9.60 4.10 5.50

Home

8.80 4.70 4.10

Away

8.60 3.30 5.30

Latest Corner Odds

Total Corners

Over 9.5

-149

Under 9.5

+106

Inter Corners

Over 6.5

-125

Under 6.5

-112

Sassuolo Corners

Over 3.5

+120

Under 3.5

-172

Most Corners

1

-500

X

+900

2

+450

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Inter Milan vs Sassuolo Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Inter Heavy Favourites With the Betting Sites

The Full-Time Result odds suggest that Inter Milan have a 79% prospect of triumphing which results in the fact that they’re strong -385 favourites to win this Serie A encounter. Sassuolo are the +900 outsiders, with the draw being a different option which could yield dividends.

Inter -1.75 on the Asian Handicap at -108 would mean a full payout if they are able to beat Sassuolo by 3+ goals. A two-goal victory means half your stake wins and the other half is refunded.

The Total Goals market reveals that Over 2.5 Goals is the current betting favourite. There are always two Both Teams to Score choices, with Yes available at -110 and No at -123.

You can find hundreds of markets for every Serie A match, with the top betting apps creating lots of different options. Check out the pre-game and In-Play selections before placing your football bets.

Full-Time Result

1

-385

X

+475

2

+900

Half-Time Result

1

-149

X

+185

2

+650

Double Chance

1X

-2500

12

-769

X2

+255

Draw No Bet

1

-1429

2

+575

Asian Handicap

1 Hcp -1.75

-108

2 Hcp +1.75

-116

Total Goals

Under 2.5

+155

Over 2.5

-208

Both Teams to Score

Yes

-110

No

-123

Lautaro Martínez Top of First Goalscorer List

Favourite Lautaro Martínez is available at +230 to be the First Goalscorer. Similar odds apply if you’re interested in him to score the last goal.

Lautaro Martínez (Inter)

First

-154

Anytime

+230

Marcus Thuram (Inter)

First

+102

Anytime

+320

Ange-Yoan Bonny (Inter)

First

+220

Anytime

+525

Hakan Çalhanoglu (Inter)

First

+290

Anytime

+800

Federico Dimarco (Inter)

First

+350

Anytime

+950

Denzel Dumfries (Inter)

First

+360

Anytime

+1000

Andrea Pinamonti (Sassuolo)

First

+370

Anytime

+1000

Andy Diouf (Inter)

First

+380

Anytime

+950

Domenico Berardi (Sassuolo)

First

+400

Anytime

+1100

Henrikh Mkhitaryan (Inter)

First

+400

Anytime

+1100

Armand Laurienté (Sassuolo)

First

+420

Anytime

+1050

Nicolò Barella (Inter)

First

+450

Anytime

+1300

Nicholas Pierini (Sassuolo)

First

+475

Anytime

+1200

Kristian Thorstvedt (Sassuolo)

First

+575

Anytime

+1500

Petar Sucic (Inter)

First

+600

Anytime

+1500

Stefan de Vrij (Inter)

First

+800

Anytime

+2200

Alieu Fadera (Sassuolo)

First

+950

Anytime

+2200

Ange-Yoan Bonny (Inter)

Over 0.5

-172

Under 0.5

+108

Lautaro Martínez (Inter)

Over 1.5

-143

Under 1.5

-111

Marcus Thuram (Inter)

Over 1.5

-115

Under 1.5

-135

Federico Dimarco (Inter)

Over 0.5

-111

Under 0.5

-139

Andrea Pinamonti (Sassuolo)

Over 0.5

-104

Under 0.5

-152

Hakan Çalhanoglu (Inter)

Over 0.5

-103

Under 0.5

-152

Domenico Berardi (Sassuolo)

Over 0.5

+107

Under 0.5

-172

Denzel Dumfries (Inter)

Over 0.5

+107

Under 0.5

-164

Armand Laurienté (Sassuolo)

Over 0.5

+120

Under 0.5

-192

Nicholas Pierini (Sassuolo)

Over 0.5

+128

Under 0.5

-208

Andy Diouf (Inter)

Over 0.5

+130

Under 0.5

-208

Henrikh Mkhitaryan (Inter)

Over 0.5

+145

Under 0.5

-238

Nicolò Barella (Inter)

Over 0.5

+170

Under 0.5

-286

Kristian Thorstvedt (Sassuolo)

Over 0.5

+175

Under 0.5

-294

Petar Sucic (Inter)

Over 0.5

+220

Under 0.5

-400

Alieu Fadera (Sassuolo)

Over 0.5

+290

Under 0.5

-526

Stefan de Vrij (Inter)

Over 0.5

+300

Under 0.5

-667

Lautaro Martínez (Inter)

Over 4.5

+115

Under 4.5

-

Marcus Thuram (Inter)

Over 3.5

-130

Under 3.5

-

Ange-Yoan Bonny (Inter)

Over 2.5

-105

Under 2.5

-

Hakan Çalhanoglu (Inter)

Over 1.5

-161

Under 1.5

-

Federico Dimarco (Inter)

Over 1.5

-149

Under 1.5

-

Denzel Dumfries (Inter)

Over 1.5

-135

Under 1.5

-

Andrea Pinamonti (Sassuolo)

Over 1.5

-156

Under 1.5

-

Andy Diouf (Inter)

Over 1.5

+117

Under 1.5

-

Domenico Berardi (Sassuolo)

Over 1.5

-141

Under 1.5

-

Henrikh Mkhitaryan (Inter)

Over 1.5

+125

Under 1.5

-

Armand Laurienté (Sassuolo)

Over 1.5

-119

Under 1.5

-

Nicolò Barella (Inter)

Over 1.5

+143

Under 1.5

-

Nicholas Pierini (Sassuolo)

Over 1.5

+105

Under 1.5

-

Kristian Thorstvedt (Sassuolo)

Over 1.5

+145

Under 1.5

-

Petar Sucic (Inter)

Over 0.5

-200

Under 0.5

-

Six Inter Wins From Their Past Ten Home Matches

Inter have six victories, two draws and two defeats in the last 10 home matches, netting an average of 2.10 goals per game and conceding 1.30.

Sassuolo have secured five victories, three defeats and two draws in the previous 10 away games, netting an average of 1.90 goals per match and conceding 1.40.

The previous Giuseppe Meazza encounter involved a 2-1 Sassuolo win against Inter. The past 6 H2H meetings at Giuseppe Meazza have involved two wins each and two draws.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Inter Milan Home Stats		6-2-2	3.40	2.10	1.30	8	2	7	3
Sassuolo Away Stats		5-2-3	3.30	1.90	1.40	7	3	7	3

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

Inter Milan vs Sassuolo Lineups & Team News

Before making your bets, take a look at the Inter vs Sassuolo team news. We’ll have the predicted and confirmed Serie A lineups for you plus all the latest on player injuries.

Inter Milan Team Page Sassuolo Team Page