LDU Quito vs São Paulo Prediction, Betting Tips, Lineups & Odds | 18 Sep 2025

Copa Libertadores Betting Preview: LDU Quito vs São Paulo

Ecuadorian LigaPro team LDU Quito host Brazilian Série A side São Paulo in the first leg of this Copa Libertadores quarter-final tie, with kick-off set for 18:00 on Thursday 18 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and confirmed lineups.

We Predict a Close Encounter

The draw can be a favourable outcome when wagering São Paulo +0.5 at an Asian Handicap price of -103. Tricolor Paulista should be able to avoid a loss against LDU Quito and this wager has the numbers to secure a return.

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4-2 Victory for LDU in Last H2H

LDU Quito triumphed in their last game. It was on the road at Estadio Federativo Reina del Cisne where Libertad were beaten 1-0 in the LigaPro.

São Paulo claimed a home victory in their previous match. A 1-0 Série A win occurred against Botafogo. Hernan Crespo's men had three shots on goal and 48% possession, with Juan Dinenno striking early in the first half.

In the round of 16, LDU claimed a 2-1 aggregate win over Brazilian Série A club Botafogo, while São Paulo advanced on penalties against Colombian Categoria Primera A side Atlético Nacional after a 1-1 draw on aggregate.

Head-to-Head Statistics

LDU won the last clash between the pair. Landing a 4-2 home victory when facing São Paulo in the Copa Libertadores.

Copa Libertadores		G	W	D	L	GF	GA	GD	GD	P
1	LDU Quito	6	3	2	1	8	4	4	8:4	11
1	São Paulo	6	4	2	0	10	4	6	10:4	14

View Full Table

Confirmed Lineups

LDU Quito confirmed lineup (4-4-2): Gonzalo Valle (GK), Ricardo Ade, Gian Allala, Leonel Quinonez, Carlos Gruezo, Jose Quinteros, Gabriel Villamil, Fernando Cornejo, Bryan Ramirez, Lisandro Alzugaray, Jeison Medina.

São Paulo confirmed lineup (3-5-2): Rafael (GK), Robert Arboleda, Alan Franco, Nahuel Ferraresi, Cedric Soares, Marcos Antonio, Pablo Maia, Damian Bobadilla, Enzo Hernan Diaz, Luciano Neves, Emiliano Ariel Rigoni.

LDU Quito vs São Paulo Prediction & Betting Tips

Our LDU Quito vs São Paulo betting guide delivers expert insight, including a main match pick, scoreline advice, standout player props and bet builder recommendations. Dive into each section below for more.

Match Prediction

São Paulo look like a great betting option with a +0.5 goal start. They should be able to triumph or potentially draw this Copa Libertadores match, with this Asian Handicap pick at -103 looking like value.

The football betting tips stem from knowing the team news and the latest form for each side. We work hard to unearth the most pertinent Copa Libertadores stats which can also act as a guide.

Key LDU Quito vs São Paulo Copa Libertadores & league stats:

• The +0.5 line has been covered by São Paulo in 9 of their last 10 games.
• The +0.5 line has been covered by São Paulo in 4 of their last 5 games.
• The -0.5 line hasn’t been covered by LDU in 6 of their last 10 games.
• The -0.5 line hasn’t been covered by LDU in 3 of their last 5 games.

São Paulo +0.5 Probability

According to the latest odds, there’s a 50.8% likelihood of our pick winning. In our opinion, there’s actually a probability of success between 55-60%. This is why we regard this as a value wager.

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Our Match Prediction

São Paulo Asian Hcp +0.5 @ -103 Bet Now

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Correct Score Prediction

LDU 1 - 1 São Paulo

We think there’s a chance of a 1-1 draw and this can be backed at odds of +480. We like placing a bet on correct score due to the fun element and the big potential return.

Player Prop Picks

Top Pick: André Oliveira Silva Under 0.5 Shots On Target -152

André Oliveira Silva (São Paulo) can be wagered to fail to have a shot on goal at -152. All things considered, we think that the betting odds are really appealing when it comes to backing him on the Shots Target market.

Latest André Oliveira Silva Player Prop Odds

Goalscorer

Anytime

+525

First

+950

Shots On Target

Over 0.5

+130

Under 0.5

-208

Shots

Over 1.5

-127

Under 1.5

-

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Kevin Andrés Minda To Score +600

Kevin Andrés Minda (LDU) can be backed at +600 to be on the scoresheet. We’ll take a chance with this Anytime Goalscorer wager as the betting odds look really appealing.

Latest Kevin Andrés Minda Player Prop Odds

Goalscorer

Anytime

+700

First

+1200

Shots On Target

Over 0.5

+175

Under 0.5

-294

Shots

Over 1.5

+128

Under 1.5

-

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LDU Quito vs São Paulo Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Bookies Have LDU as Favourites

With the bookies giving them a 48% probability of winning, LDU Quito might be a popular acca pick. Their current betting odds are +107 when it comes to triumphing in this Copa Libertadores clash. The market implies that São Paulo are the most unlikely to win at +350.

Should you want to back LDU to lead at the break, then there is +190 available on the Half-Time Result market. Opponents São Paulo have been chalked up at +410 and the draw is -114.

The Total Goals market is a great option and Under 2.5 Goals has the shortest odds right now. A fresh approach might involve siding with a BTTS wager and there’s -213 on offer for Both Teams to Score No.

Hundreds of markets are now a guarantee for each of the Copa Libertadores games, with the best football betting sites making sure that customers have quality options.

Full-Time Result

1

+107

X

+188

2

+350

Half-Time Result

1

+190

X

-114

2

+410

Double Chance

1X

-500

12

-244

X2

-137

Draw No Bet

1

-263

2

+185

Asian Handicap

1 Hcp -0.5

+106

2 Hcp +0.5

-130

Total Goals

Under 2.5

-278

Over 2.5

+215

Both Teams to Score

Yes

+148

No

-213

Luciano da Rocha Top of First Goalscorer List

There’s the chance to back Luciano da Rocha at +500 to be the First Goalscorer. He’s the favourite and available at similar odds to find the net last instead.

Luciano da Rocha (São Paulo)

First

+270

Anytime

+500

Michael Estrada (LDU)

First

+320

Anytime

+600

Lautaro Pastrán (LDU)

First

+500

Anytime

+900

André Oliveira Silva (São Paulo)

First

+525

Anytime

+950

Aldemir Ferreira (São Paulo)

First

+550

Anytime

+1000

Emiliano Rigoni (São Paulo)

First

+600

Anytime

+1300

Kevin Andrés Minda (LDU)

First

+700

Anytime

+1200

Oscar (São Paulo)

First

+700

Anytime

+1300

Gabriel Villamíl (LDU)

First

+700

Anytime

+1400

Fernando Cornejo (LDU)

First

+700

Anytime

+1400

Gian Franco Allala Menéndez (LDU)

First

+900

Anytime

+1900

Damián Bobadilla (São Paulo)

First

+1000

Anytime

+2000

Leonel Quiñónez (LDU)

First

+1000

Anytime

+2000

Carlos Gruezo (LDU)

First

+1000

Anytime

+2200

Rodrigo Almeida Mendonca "Rodriguinho" (São Paulo)

First

+1150

Anytime

+2000

Michael Estrada (LDU)

Over 0.5

-189

Under 0.5

+110

Luciano da Rocha (São Paulo)

Over 0.5

-161

Under 0.5

-106

Lautaro Pastrán (LDU)

Over 0.5

+115

Under 0.5

-182

Gabriel Villamíl (LDU)

Over 0.5

+120

Under 0.5

-204

André Oliveira Silva (São Paulo)

Over 0.5

+130

Under 0.5

-208

Aldemir Ferreira (São Paulo)

Over 0.5

+135

Under 0.5

-217

Kevin Andrés Minda (LDU)

Over 0.5

+175

Under 0.5

-294

Emiliano Rigoni (São Paulo)

Over 0.5

+180

Under 0.5

-333

Oscar (São Paulo)

Over 0.5

+190

Under 0.5

-333

Fernando Cornejo (LDU)

Over 0.5

+190

Under 0.5

-370

Damián Bobadilla (São Paulo)

Over 0.5

+250

Under 0.5

-556

Gian Franco Allala Menéndez (LDU)

Over 0.5

+260

Under 0.5

-588

Rodrigo Almeida Mendonca "Rodriguinho" (São Paulo)

Over 0.5

+260

Under 0.5

-500

Leonel Quiñónez (LDU)

Over 0.5

+310

Under 0.5

-833

Carlos Gruezo (LDU)

Over 0.5

+320

Under 0.5

-833

Michael Estrada (LDU)

Over 3.5

+110

Under 3.5

-

Luciano da Rocha (São Paulo)

Over 2.5

-122

Under 2.5

-

Gabriel Villamíl (LDU)

Over 2.5

-135

Under 2.5

-

Lautaro Pastrán (LDU)

Over 1.5

-156

Under 1.5

-

André Oliveira Silva (São Paulo)

Over 1.5

-127

Under 1.5

-

Aldemir Ferreira (São Paulo)

Over 1.5

-123

Under 1.5

-

Emiliano Rigoni (São Paulo)

Over 1.5

+132

Under 1.5

-

Kevin Andrés Minda (LDU)

Over 1.5

+128

Under 1.5

-

Oscar (São Paulo)

Over 1.5

+150

Under 1.5

-

Fernando Cornejo (LDU)

Over 1.5

+143

Under 1.5

-

Damián Bobadilla (São Paulo)

Over 1.5

+112

Under 1.5

-

Leonel Quiñónez (LDU)

Over 1.5

+155

Under 1.5

-

Gian Franco Allala Menéndez (LDU)

Over 0.5

-175

Under 0.5

-

Carlos Gruezo (LDU)

Over 0.5

-179

Under 0.5

-

Rodrigo Almeida Mendonca "Rodriguinho" (São Paulo)

Over 0.5

-222

Under 0.5

-

Latest Copa Libertadores and domestic league stats. Full Time Result, Goals, Corners and Possession.

LDU Quito Stats

São Paulo Stats

Full-Time Result

• 5 wins, 2 defeats and 3 draws in the previous 10 matches
• 4 wins and 6 draws in the previous 10 home matches

Full-Time Result

• 7 wins, 1 defeat and 2 draws in the previous 10 matches
• 2 wins, 4 defeats and 4 draws in the previous 10 away matches

Goals

• An average of 1.40 goals scored and 0.70 conceded in the previous 10 matches
• An average of 1.80 goals scored and 1.20 conceded in the previous 10 home matches
• An average of 2.10 goals per game in the previous 10 matches
• An average of 3.00 goals per game in the previous 10 home matches
• BTTS Yes in 4 of the previous 10 matches
• BTTS Yes in 9 of the previous 10 home matches
• Over 2.5 Goals in 3 of the previous 10 matches
• Over 2.5 Goals in 5 of the previous 10 home matches

Goals

• An average of 1.70 goals scored and 0.70 conceded in the previous 10 matches
• An average of 1.10 goals scored and 1.40 conceded in the previous 10 away matches
• An average of 2.40 goals per game in the previous 10 matches
• An average of 2.50 goals per game in the previous 10 away matches
• BTTS Yes in 4 of the previous 10 matches
• BTTS Yes in 6 of the previous 10 away matches
• Over 2.5 Goals in 4 of the previous 10 matches
• Over 2.5 Goals in 5 of the previous 10 away matches

LDU Quito vs São Paulo Lineups & Team News

Be prepared — check the LDU vs São Paulo team news before wagering. We’ll offer the predicted and confirmed Copa Libertadores lineups along with the latest injury developments.