LDU Quito vs São Paulo Prediction, Betting Tips, Lineups & Odds | 18 Sep 2025

Copa Libertadores Betting Preview: LDU Quito vs São Paulo

Ecuadorian LigaPro team LDU Quito host Brazilian Série A side São Paulo in the first leg of this Copa Libertadores quarter-final tie, with kick-off set for 18:00 on Thursday 18 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and confirmed lineups.

We Predict a Close Encounter

The draw can be a favourable outcome when wagering São Paulo +0.5 at an Asian Handicap price of -103. They should be able to avoid a loss against LDU Quito and this wager has the numbers to secure a return.

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4-2 Victory for LDU in Last H2H

LDU Quito triumphed in their last game. It was on the road at Estadio Federativo Reina del Cisne where Libertad were beaten 1-0 in the LigaPro.

São Paulo claimed a home victory in their previous match. A 1-0 Série A win occurred against Botafogo. Hernan Crespo's men had three shots on goal and 48% possession, with Juan Dinenno striking early in the first half.

In the round of 16, LDU claimed a 2-1 aggregate win over Brazilian Série A club Botafogo, while São Paulo advanced on penalties against Colombian Categoria Primera A side Atlético Nacional after a 1-1 draw on aggregate.

Head-to-Head Statistics

LDU won the last clash between the pair. Landing a 4-2 home victory when facing São Paulo in the Copa Libertadores.

Copa Libertadores		G	W	D	L	GF	GA	GD	GD	P
1	LDU Quito	6	3	2	1	8	4	4	8:4	11
1	São Paulo	6	4	2	0	10	4	6	10:4	14

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LDU Quito vs São Paulo Prediction & Betting Tips

Our LDU Quito vs São Paulo betting guide delivers expert insight, including a main match pick, scoreline advice, standout player props and bet builder recommendations. Dive into each section below for more.

Match Prediction

São Paulo look like a great betting option with a +0.5 goal start. They should be able to triumph or potentially draw this Copa Libertadores match, with this Asian Handicap pick at -103 looking like value.

The football betting tips stem from knowing the team news and the latest form for each side. We work hard to unearth the most pertinent Copa Libertadores stats which can also act as a guide.

Key LDU Quito vs São Paulo Copa Libertadores & league stats:

• The +0.5 line has been covered by São Paulo in 9 of their last 10 games.
• The +0.5 line has been covered by São Paulo in 4 of their last 5 games.
• The -0.5 line hasn’t been covered by LDU in 6 of their last 10 games.
• The -0.5 line hasn’t been covered by LDU in 3 of their last 5 games.

São Paulo +0.5 Probability

According to the latest odds, there’s a 50.8% likelihood of our pick winning. In our opinion, there’s actually a probability of success between 55-60%. This is why we regard this as a value wager.

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Our Match Prediction

São Paulo Asian Hcp +0.5 @ -103 Watch Live Bet Now

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Correct Score Prediction

LDU 1 - 1 São Paulo

We think there’s a chance of a 1-1 draw and this can be backed at odds of +525. We like placing a bet on correct score due to the fun element and the big potential return.

Player Prop Picks

Top Pick: André Oliveira Silva Under 0.5 Shots On Target -152

André Oliveira Silva (São Paulo) can be wagered to fail to have a shot on goal at -152. All things considered, we think that the betting odds are really appealing when it comes to backing him on the Shots Target market.

Latest André Oliveira Silva Player Prop Odds

Goalscorer

Anytime

+450

First

+900

Shots On Target

Over 0.5

-103

Under 0.5

-152

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Kevin Andrés Minda To Score +600

Kevin Andrés Minda (LDU) can be backed at +600 to be on the scoresheet. We’ll take a chance with this Anytime Goalscorer wager as the betting odds look really appealing.

Latest Kevin Andrés Minda Player Prop Odds

Goalscorer

Anytime

+600

First

+1200

Shots On Target

Over 0.5

+160

Under 0.5

-270

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LDU Quito vs São Paulo Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Bookies Have LDU as Favourites

With the bookies giving them a 54% probability of winning, LDU Quito might be a popular acca pick. Their current betting odds are -119 when it comes to triumphing in this Copa Libertadores clash. The market implies that São Paulo are the most unlikely to win at +360.

Should you want to back LDU to lead at the break, then there is +155 available on the Half-Time Result market. Opponents São Paulo have been chalked up at +410 and the draw is +107.

The Total Goals market is a great option and Under 2.5 Goals has the shortest odds right now. A fresh approach might involve siding with a BTTS wager and there’s -164 on offer for Both Teams to Score No.

Hundreds of markets are now a guarantee for each of the Copa Libertadores games, with the best football betting sites making sure that customers have quality options.

Full-Time Result

1

-119

X

+240

2

+360

Half-Time Result

1

+155

X

+107

2

+410

Double Chance

1X

-500

12

-333

X2

-108

Draw No Bet

1

-313

2

+210

Asian Handicap

1 Hcp -0.5

-120

2 Hcp +0.5

-103

Total Goals

Under 2.5

-179

Over 2.5

+143

Both Teams to Score

Yes

+118

No

-164

Michael Estrada Top of First Goalscorer List

There’s the chance to back Michael Estrada at +550 to be the First Goalscorer. He’s the favourite and available at similar odds to find the net last instead.

Michael Estrada (LDU)

First

+265

Anytime

+550

Luciano da Rocha (São Paulo)

First

+360

Anytime

+700

André Oliveira Silva (São Paulo)

First

+450

Anytime

+900

Lautaro Pastrán (LDU)

First

+460

Anytime

+950

Aldemir Ferreira (São Paulo)

First

+475

Anytime

+950

Kevin Andrés Minda (LDU)

First

+600

Anytime

+1200

Oscar (São Paulo)

First

+600

Anytime

+1200

Emiliano Rigoni (São Paulo)

First

+650

Anytime

+1300

Fernando Cornejo (LDU)

First

+650

Anytime

+1300

Gabriel Villamíl (LDU)

First

+700

Anytime

+1400

Gian Franco Allala Menéndez (LDU)

First

+750

Anytime

+1900

Leonel Quiñónez (LDU)

First

+800

Anytime

+1900

Damián Bobadilla (São Paulo)

First

+1000

Anytime

+2000

Rodrigo Almeida Mendonca "Rodriguinho" (São Paulo)

First

+1050

Anytime

+2000

Carlos Gruezo (LDU)

First

+1100

Anytime

+2200

Michael Estrada (LDU)

Over 0.5

-208

Under 0.5

+120

Luciano da Rocha (São Paulo)

Over 0.5

-161

Under 0.5

+102

André Oliveira Silva (São Paulo)

Over 0.5

-103

Under 0.5

-152

Aldemir Ferreira (São Paulo)

Over 0.5

-100

Under 0.5

-156

Lautaro Pastrán (LDU)

Over 0.5

+110

Under 0.5

-172

Oscar (São Paulo)

Over 0.5

+143

Under 0.5

-238

Kevin Andrés Minda (LDU)

Over 0.5

+160

Under 0.5

-270

Emiliano Rigoni (São Paulo)

Over 0.5

+160

Under 0.5

-263

Gabriel Villamíl (LDU)

Over 0.5

+160

Under 0.5

-270

Fernando Cornejo (LDU)

Over 0.5

+170

Under 0.5

-294

Rodrigo Almeida Mendonca "Rodriguinho" (São Paulo)

Over 0.5

+200

Under 0.5

-357

Damián Bobadilla (São Paulo)

Over 0.5

+215

Under 0.5

-385

Gian Franco Allala Menéndez (LDU)

Over 0.5

+250

Under 0.5

-556

Leonel Quiñónez (LDU)

Over 0.5

+280

Under 0.5

-667

Carlos Gruezo (LDU)

Over 0.5

+310

Under 0.5

-667

Latest Copa Libertadores and domestic league stats. Full Time Result, Goals, Corners and Possession.

LDU Quito Stats

São Paulo Stats

Full-Time Result

• 5 wins, 2 defeats and 3 draws in the previous 10 matches
• 4 wins and 6 draws in the previous 10 home matches

Full-Time Result

• 7 wins, 1 defeat and 2 draws in the previous 10 matches
• 2 wins, 4 defeats and 4 draws in the previous 10 away matches

Goals

• An average of 1.40 goals scored and 0.70 conceded in the previous 10 matches
• An average of 1.80 goals scored and 1.20 conceded in the previous 10 home matches
• An average of 2.10 goals per game in the previous 10 matches
• An average of 3.00 goals per game in the previous 10 home matches
• BTTS Yes in 4 of the previous 10 matches
• BTTS Yes in 9 of the previous 10 home matches
• Over 2.5 Goals in 3 of the previous 10 matches
• Over 2.5 Goals in 5 of the previous 10 home matches

Goals

• An average of 1.70 goals scored and 0.70 conceded in the previous 10 matches
• An average of 1.10 goals scored and 1.40 conceded in the previous 10 away matches
• An average of 2.40 goals per game in the previous 10 matches
• An average of 2.50 goals per game in the previous 10 away matches
• BTTS Yes in 4 of the previous 10 matches
• BTTS Yes in 6 of the previous 10 away matches
• Over 2.5 Goals in 4 of the previous 10 matches
• Over 2.5 Goals in 5 of the previous 10 away matches

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LDU Quito vs São Paulo Lineups & Team News

Be prepared — check the LDU vs São Paulo team news before wagering. We’ll offer the predicted and confirmed Copa Libertadores lineups along with the latest injury developments.