Mainz vs Bayer Leverkusen Prediction, Betting Tips, Lineups & Odds | 18 Oct 2025

Bundesliga Betting Preview: Mainz vs Bayer Leverkusen

Mainz host Bayer Leverkusen in this German Bundesliga clash at MEWA Arena, with kick-off set for 09:30 on Saturday 18 October. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

Goals the Pick in Mainz vs Leverkusen

We can’t pass up the chance to bet on odds of -147 for Over 2.5 on the Total Goals market. The stats imply that Mainz and Bayer Leverkusen will produce at least three goals and we’ll play this selection with confidence.

Feeling our Total Goals pick? Have a quick read of our BetMGM review and grab the latest promo code before you place your bet.

2-2 Draw in Previous H2H

Mainz 05 have lost three straight games at home. In their last appearance, they suffered a 4-0 away loss to Hamburger SV at Volksparkstadion. The Rhineland-Palatinate side boasted 60% possession and recorded four shots on target.

Bayer Leverkusen made it back-to-back Bundesliga wins after a 2-0 home success over Union Berlin at BayArena. The Werkself had four shots on goal and enjoyed 69% possession, while Ernest Poku and Christian Kofane were on the scoresheet.

Head-to-Head Statistics

Leverkusen have not lost any of the past four games against Mainz, with the last clash seeing a 2-2 draw played out at MEWA Arena. The past 10 H2H matches have included six Leverkusen victories, two draws and two Mainz wins.

Bundesliga		G	W	D	L	GF	GA	GD	GD	P
5	Leverkusen	7	4	2	1	16	11	5	16:11	14
16	Mainz 05	7	1	1	5	8	14	-6	8:14	4

View Full Table

Mainz have 2 wins, 5 losses and 3 draws, averaging 1.2 goals from 3.6 shots on goal and 13.4 attempts. The 05ers have averaged 52.8% possession, 413.9 passes and 6.4 corners per match, with the opposition scoring 1.7 goals from 4.4 shots on goal, 11.1 attempts and 3.7 corners.

Top goalscorers Paul Nebel and Jonathan Burkardt have found the net 3 times, with Nadiem Amiri scoring 2. Andreas Hanche-Olsen, Kaishu Sano and Nadiem Amiri have racked up the most assists with 1 each.

Leverkusen have 4 victories, 2 defeats and 4 draws, with an average of 2.0 goals from 5.3 shots on goal and 11.9 attempts. Kasper Hjulmand's team have averaged 56.9% possession, 558.3 passes, 4.4 corners taken and 5.5 corners against, while conceding 1.6 goals from 4.4 shots on goal and 11.9 attempts.

Patrik Schick has scored 6, followed by Ernest Poku, Malik Tillman and Alejandro Grimaldo with 2 goals apiece. Alejandro Grimaldo and Nathan Tella have clocked up 3 assists, with Mark Flekken keeping one clean sheet in the last 10 games.

Confirmed Lineups

Mainz confirmed lineup (3-4-2-1): Lasse Rieß (GK), Danny da Costa, Stefan Bell, Dominik Kohr, Nikolas Veratschnig, Kaishu Sano, Nadiem Amiri, Phillipp Mwene, Paul Nebel, Jae-Sung Lee, Benedict Hollerbach.

Bayer Leverkusen confirmed lineup (3-4-2-1): Mark Flekken (GK), Loïc Badé, Robert Andrich, Edmond Tapsoba, Arthur, Ezequiel Fernández, Aleix Garcia, Alejandro Grimaldo, Ernest Poku, Jonas Hofmann, Christian Kofane.

Mainz vs Bayer Leverkusen Prediction & Betting Tips

Get the full betting picture for Mainz vs Bayer Leverkusen, including our expert match prediction, likely scoreline, key corners pick, must-watch player props and a tailored bet builder ready to use.

Match Prediction

A generous price of -147 is on offer when it comes to Over 2.5 Goals to be notched and that looks like a great betting opportunity. Back at least three goals to be scored when it comes to this Bundesliga encounter.

We only create the football betting tips after consulting the latest Bundesliga team news along with the form of both sides. There are also stats that can be mined to good effect to come up with predictions.

Key Mainz vs Bayer Leverkusen league stats:

• The 2.5 line has been covered in the last 4 Leverkusen games on the road.
• The 2.5 line has been covered in 7 of the last 10 Leverkusen games.
• The 2.5 line has been covered in 10 of the last 17 Leverkusen games on the road.
• The 2.5 line has been covered in 7 of the last 10 games between these teams.

Over 2.5 Probability

If you go by the best football betting sites, our pick has a 59.5% chance of delivering a return. However, our research has found that the actual probability is between 65-70%. This is why we can recommend this wager.

Over 2.5 Goals backers in search of larger odds could consider the Result & Total Goals market. This involves getting a bigger price if you’re correctly able to predict a team to win.

Before placing your wager, explore the best betting offers. Our in-depth bonus guide features a wide range of promotions to choose from.

Our Match Prediction

Over 2.5 Goals @ -147 Bet Now

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Correct Score Prediction

Mainz 2 - 1 Leverkusen

An exciting bet could be a 2-1 victory in favor of Mainz at odds of +800. A correct score wager provides a fun alternative and a nice potential return on the cards.

Player Prop Picks

Top Pick: Nadiem Amiri Over 0.5 Shots On Target -102

Nadiem Amiri (Mainz) has racked up at least one shot on goal in seven of his past ten Bundesliga matches. It certainly looks possible that he will cover the Shots on Target line and there are odds of -102 up for grabs.

Latest Nadiem Amiri Player Prop Odds

Goalscorer

Anytime

+330

First

+850

Shots On Target

Over 0.5

-116

Under 0.5

-133

Shots

Over 2.5

+130

Under 2.5

-

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Paul Nebel to Score +350

Paul Nebel (Mainz) has registered three goals in his past eight Bundesliga games. When it comes to him finding the net, we believe the +350 available is appealing when backing him on the Anytime Goalscorer market.

Latest Paul Nebel Player Prop Odds

Goalscorer

Anytime

+310

First

+800

Shots On Target

Over 0.5

-120

Under 0.5

-130

Shots

Over 1.5

-156

Under 1.5

-

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Corners Prediction

Leverkusen Under 4.5 Corners -138

Bayer Leverkusen have failed to cover the 4.5 corners line in four consecutive matches, while Mainz have conceded 3.40 corners on average in their previous 5 home games. We think that Leverkusen will come up short and this Team Corners bet can be backed at -138.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Mainz

Total

10.10 6.40 3.70

Home

9.10 5.30 3.80

Away

9.80 4.90 4.90

Leverkusen

Total

9.90 4.40 5.50

Home

9.30 5.80 3.50

Away

9.90 5.20 4.70

Latest Corner Odds

Total Corners

Over 9.5

-143

Under 9.5

-100

Mainz Corners

Over 5.5

+110

Under 5.5

-150

Leverkusen Corners

Over 4.5

-120

Under 4.5

-120

Most Corners

1

-125

X

+650

2

+138

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Mainz vs Bayer Leverkusen Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Betting Sites Expecting Tight Affair

Mainz 05 are currently available at +155 with the bookmakers to defeat Bayer Leverkusen, with the latter available at the same price. If you’re siding with the draw in this Bundesliga clash, then it can be backed at +255.

There are various ways to back Mainz and one option is the Asian Handicap -0.25. There’s +120 currently available that they beat Leverkusen and there’s half a stake refund if the scoreline ends level.

The Total Goals odds suggest that Over 2.5 is a strong probability in this contest. If you think both teams will score, then you can back BTTS Yes at -182.

There are hundreds of markets which means lots of options to find a football bet for the latest Bundesliga match. The best betting sites leave no stone unturned to provide a first-class service.

Full-Time Result

1

+155

X

+255

2

+155

Half-Time Result

1

+205

X

+135

2

+200

Double Chance

1X

-208

12

-357

X2

-204

Draw No Bet

1

-118

2

-115

Asian Handicap

1 Hcp -0.25

+120

2 Hcp +0.25

-149

Total Goals

Under 2.5

+118

Over 2.5

-154

Both Teams to Score

Yes

-182

No

+138

Patrik Schick Favourite to Score the First Goal

There is +145 available that Patrik Schick finds the net, while he is available at +350 to register the first goal which makes him favourite.

Patrik Schick (Leverkusen)

First

+145

Anytime

+350

Benedict Hollerbach (Mainz)

First

+220

Anytime

+600

Christian Michel Kofane (Leverkusen)

First

+230

Anytime

+500

Nelson Weiper (Mainz)

First

+290

Anytime

+650

Paul Nebel (Mainz)

First

+310

Anytime

+800

Armindo Sieb (Mainz)

First

+330

Anytime

+800

Álex Grimaldo (Leverkusen)

First

+330

Anytime

+800

Nadiem Amiri (Mainz)

First

+330

Anytime

+850

Jae-sung Lee (Mainz)

First

+330

Anytime

+850

Jonas Hofmann (Leverkusen)

First

+340

Anytime

+850

Malik Tillman (Leverkusen)

First

+350

Anytime

+850

Ernest Poku (Leverkusen)

First

+360

Anytime

+850

Arnaud Nordin (Mainz)

First

+380

Anytime

+950

William Bøving (Mainz)

First

+400

Anytime

+900

Eliesse Ben Seghir (Leverkusen)

First

+400

Anytime

+900

Aleix Garcia (Leverkusen)

First

+525

Anytime

+1300

Robert Andrich (Leverkusen)

First

+575

Anytime

+1500

Claudio Echeverri (Leverkusen)

First

+600

Anytime

+1400

Dominik Kohr (Mainz)

First

+600

Anytime

+1700

Silvan Widmer (Mainz)

First

+650

Anytime

+1700

Danny Da Costa (Mainz)

First

+650

Anytime

+2000

Edmond Tapsoba (Leverkusen)

First

+800

Anytime

+2200

Andreas Hanche-Olsen (Mainz)

First

+850

Anytime

+2000

Benedict Hollerbach (Mainz)

Over 0.5

-192

Under 0.5

+112

Christian Michel Kofane (Leverkusen)

Over 0.5

-152

Under 0.5

-111

Nelson Weiper (Mainz)

Over 0.5

-133

Under 0.5

-116

Paul Nebel (Mainz)

Over 0.5

-120

Under 0.5

-130

Nadiem Amiri (Mainz)

Over 0.5

-116

Under 0.5

-133

Jae-sung Lee (Mainz)

Over 0.5

-111

Under 0.5

-143

Armindo Sieb (Mainz)

Over 0.5

-108

Under 0.5

-147

Ernest Poku (Leverkusen)

Over 0.5

-100

Under 0.5

-156

Jonas Hofmann (Leverkusen)

Over 0.5

+102

Under 0.5

-161

Malik Tillman (Leverkusen)

Over 0.5

+107

Under 0.5

-167

Álex Grimaldo (Leverkusen)

Over 0.5

+112

Under 0.5

-179

Arnaud Nordin (Mainz)

Over 0.5

+112

Under 0.5

-179

William Bøving (Mainz)

Over 0.5

+120

Under 0.5

-200

Eliesse Ben Seghir (Leverkusen)

Over 0.5

+123

Under 0.5

-200

Patrik Schick (Leverkusen)

Over 1.5

+130

Under 1.5

-208

Aleix Garcia (Leverkusen)

Over 0.5

+185

Under 0.5

-333

Claudio Echeverri (Leverkusen)

Over 0.5

+200

Under 0.5

-357

Dominik Kohr (Mainz)

Over 0.5

+215

Under 0.5

-435

Robert Andrich (Leverkusen)

Over 0.5

+225

Under 0.5

-455

Silvan Widmer (Mainz)

Over 0.5

+225

Under 0.5

-400

Danny Da Costa (Mainz)

Over 0.5

+275

Under 0.5

-667

Andreas Hanche-Olsen (Mainz)

Over 0.5

+300

Under 0.5

-625

Edmond Tapsoba (Leverkusen)

Over 0.5

+330

Under 0.5

-909

Patrik Schick (Leverkusen)

Over 3.5

-106

Under 3.5

-

Benedict Hollerbach (Mainz)

Over 2.5

-114

Under 2.5

-

Álex Grimaldo (Leverkusen)

Over 2.5

+135

Under 2.5

-

Nadiem Amiri (Mainz)

Over 2.5

+130

Under 2.5

-

Eliesse Ben Seghir (Leverkusen)

Over 1.5

-100

Under 1.5

-

William Bøving (Mainz)

Over 1.5

+120

Under 1.5

-

Arnaud Nordin (Mainz)

Over 1.5

-154

Under 1.5

-

Ernest Poku (Leverkusen)

Over 1.5

-139

Under 1.5

-

Malik Tillman (Leverkusen)

Over 1.5

-118

Under 1.5

-

Jonas Hofmann (Leverkusen)

Over 1.5

-122

Under 1.5

-

Jae-sung Lee (Mainz)

Over 1.5

-143

Under 1.5

-

Armindo Sieb (Mainz)

Over 1.5

-128

Under 1.5

-

Paul Nebel (Mainz)

Over 1.5

-156

Under 1.5

-

Nelson Weiper (Mainz)

Over 1.5

-161

Under 1.5

-

Christian Michel Kofane (Leverkusen)

Over 1.5

-185

Under 1.5

-

Aleix Garcia (Leverkusen)

Over 0.5

-213

Under 0.5

-

Robert Andrich (Leverkusen)

Over 0.5

-182

Under 0.5

-

Claudio Echeverri (Leverkusen)

Over 0.5

-222

Under 0.5

-

Dominik Kohr (Mainz)

Over 0.5

-179

Under 0.5

-

Danny Da Costa (Mainz)

Over 0.5

+114

Under 0.5

-

Edmond Tapsoba (Leverkusen)

Over 0.5

-102

Under 0.5

-

Leverkusen Unbeaten in Past Three H2H MEWA Arena Meetings Against Mainz

Mainz have managed five draws, three losses and two victories in the last 10 home matches, recording an average of 1.40 goals per game and conceding 1.30.

Bayer Leverkusen have not lost on their travels in the past ten matches. The Werkself have clocked up five wins and five draws in the past 10 away games, recording an average of 2.10 goals per match and conceding 1.30.

The previous MEWA Arena encounter involved a 2-2 draw between Mainz and Leverkusen. We’ve seen the past 7 H2H matches at MEWA Arena involve five wins for Leverkusen, one draw and one victory for Mainz.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Mainz Home Stats		2-5-3	2.70	1.40	1.30	4	6	6	4
Bayer Leverkusen Away Stats		5-5-0	3.40	2.10	1.30	6	4	7	3

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

Mainz vs Bayer Leverkusen Lineups & Team News

Check the Mainz vs Leverkusen team news before you place your bets. We’ll keep you posted with predicted and confirmed lineups for the Bundesliga and all current injury news.

Mainz 05 Team Page Bayer Leverkusen Team Page