Napoli vs Pisa Prediction, Betting Tips, Lineups & Odds | 22 Sep 2025
Serie A Betting Preview: Napoli vs Pisa
Napoli host Pisa in this Italian Serie A clash at Diego Armando Maradona, with kick-off set for 14:45 on Monday 22 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.
Will Pisa Keep the Scoreline Respectable?
You can wager Pisa +1.5 on the Asian Handicap when playing Napoli. This means getting odds of -104 and a return is on the cards if the underdogs are able to win, draw or lose by a single goal.
Betting on our Asian Handicap selection? Access the updated BetMGM promo code and read our expert review of the platform before locking in your bet.
Two Teams Defeated in Last Game
Napoli won last time out by a 3-1 scoreline. On the road against Fiorentina at Stadio Artemio Franchi, they made it three wins on the spin. Gli Azzurri enjoyed 47% possession and had eight shots on target, while Kevin De Bruyne, Rasmus Hoejlund and Sam Beukema got among the goals.
Four days ago, Napoli were beaten 2-0 when facing Manchester City away in the Champions League.
Pisa have lost in back-to-back Serie A outings. In a recent home game at Stadio Romeo Anconetani, they were turned over 1-0 by Udinese. The Tuscany side recorded two shots on goal and had 51% possession.
| Serie A | G | W | D | L | GF | GA | GD | GD | P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 2 |  Napoli |
3 | 3 | 0 | 0 | 6 | 1 | 5 | 6:1 | 9 |
| 18 |  Pisa |
3 | 0 | 1 | 2 | 1 | 3 | -2 | 1:3 | 1 |
Napoli have 8 wins and 2 draws, averaging 1.7 goals from 5.2 shots on goal and 14.2 attempts. Antonio Conte's side have averaged 61.0% possession, 534.9 passes and 5.4 corners per match, conceding 0.3 goals and 3.6 corners from 1.5 shots on goal and 8.3 attempts.
Scott McTominay leads the way with 7 goals, Romelu Lukaku has 3, with Kevin De Bruyne and Giacomo Raspadori scoring 2. Matteo Politano is the leading assists maker with 3, while goalie Alex Meret has 8 clean sheets.
Pisa – Last 10 League GamesPisa have 4 victories, 4 defeats and 2 draws, averaging 3.4 shots on goal, 10.4 attempts and 1.2 goals. I Nerazzurri average 46.7% possession, 4.3 corners taken and 5.0 corners against them, while 1.1 goals have been conceded from 9.3 attempts and 3.1 shots on goal.
The top scorers have been Stefano Moreo, Idrissa Toure, Alexander Lind and Matteo Tramoni, with 2 goals apiece. Stefano Moreo has managed 2 assists in the last 10 games.
Predicted & Confirmed Lineups
Napoli predicted lineup (4-1-4-1): Alex Meret (GK), Giovanni Di Lorenzo, Sam Beukema, Alessandro Buongiorno, Mathías Olivera, Stanislav Lobotka, Matteo Politano, Kevin De Bruyne, Andre Zambo Anguissa, Scott McTominay, Lorenzo Lucca.
Pisa predicted lineup (3-5-2): Adrian Semper (GK), Simone Canestrelli, Antonio Caracciolo, Mateus Lusuardi, Idrissa Touré, Ebenezer Akinsanmiro, Michel Aebischer, Matteo Tramoni, Samuele Angori, Stefano Moreo, Henrik Meister.
Napoli vs Pisa Prediction & Betting Tips
Step into Napoli vs Pisa with confidence as we bring you our main match prediction, projected scoreline, key corners betting angle, best player prop picks and a custom-built bet builder.
Match Prediction
Pisa +1.5 on the Asian Handicap are a great betting option at -104 on the basis that they can perform well as underdogs for this Serie A encounter. We’re expecting the game to be close.
Plenty of research goes into our football picks. It begins by focusing on the latest Serie A form and knowing the injury situation. The important numbers can then be utilised to help complete the picture.
Key Napoli vs Pisa league stats:
Pisa +1.5 Probability
The betting apps are estimating that there is a 51% likelihood of this pick landing a return. Taking all factors into consideration, our experts think there’s a stronger chance of success and estimate the probability to be closer to 60%. The bet can be recommended for this precise reason.
If you want to land a big potential return from a small stake, then a Bet Builder could be the way to go. Back Pisa to cover the line in a combination with other selections.
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Correct Score Prediction
1
-
0
Pisa
We’ve picked out a correct score of 1-0 being landed by Napoli. You can secure odds of +450 and this provides an alternative way to place a wager.
Player Prop Picks
Matteo Politano (Napoli) has recorded over 2.5 shots in three consecutive Serie A matches. He certainly looks capable of covering the line when it comes to this player prop and odds of +130 are currently on offer.
T&C apply. Gamble responsibly 18+
Scott McTominay (Napoli) has netted five goals in his past five Serie A home games. Considering the numbers, we think that odds of +180 offer plenty of appeal when it comes to wagering on Anytime Goalscorer.
T&C apply. Gamble responsibly 18+
Corners Prediction
Pisa have been awarded an average of 5.00 corners in the past five games, while Napoli have yielded a corner average of 3.60 in their previous ten matches. There are odds of -120 available when it comes to this Team Corners bet and we think Pisa can cover the line.
Napoli
Pisa
T&C apply. Gamble responsibly 18+
Bet Builder Tips
If you fancy a bet builder, then why not take Pisa with the +1.5 Asian Handicap, no more than two goals to be scored accompanied by Matteo Politano (Napoli) to record Over 2.5 shots.
A football bet builder is a fantastic way of cheering on different selections within the same game. You can forecast specific things to happen and enjoy larger odds compared to betting a single. The odds multiply for each leg.
Napoli vs Pisa Odds
The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.
Bookies Running Scared of Napoli Win
Napoli are overwhelming -400 favourites to win this Serie A clash based on the latest betting odds. The bookmakers afford them a 80% probability of claiming the spoils. Pisa are the +1050 underdogs, while the draw can also be backed as an alternative.
If you fancy Napoli to be leading at the interval, then you can secure odds of -137. Alternatively, there’s the chance to wager on Pisa at +800 on the Half-Time Result, with the draw trading at +150.
You’re able to back Over 2.5 Goals or Under 2.5 Goals at roughly the same price right now. If you’re expecting at least one team to keep a clean sheet, you might be interested in the -222 about Both Teams to Score No.
There are hundreds of markets which means lots of options to find a football bet for the latest Serie A match. The best betting sites leave no stone unturned to provide a first-class service.
Lorenzo Lucca Favourite to Find the Net First
Lorenzo Lucca is the market leader to be First Goalscorer at +300 while there’s also the chance to back him to find the net at +115.
Napoli Difficult to Beat on Home Soil
Napoli are unbeaten over their previous ten games at Diego Armando Maradona. Gli Azzurri have seven wins and three draws in the last 10 home games, scoring an average of 1.80 goals per match and conceding 0.70.
Pisa have recorded four victories, three draws and three defeats in the previous 10 away matches, netting an average of 1.30 goals per game and conceding 0.90.
| Last 10 League Games | W-D-L | G | GF | GA | O2.5 | U2.5 | B-Y | B-No | |
|---|---|---|---|---|---|---|---|---|---|
| Napoli Home Stats |
7-3-0 | 2.50 | 1.80 | 0.70 | 5 | 5 | 6 | 4 | |
| Pisa Away Stats |
4-3-3 | 2.20 | 1.30 | 0.90 | 4 | 6 | 5 | 5 | |
- W-D-L = Wins-Draws-Losses
- G = Avg. Goals
- GF = Avg. Goals For
- GA = Avg. Goals Against
- O2.5 = Matches Over 2.5 Goals
- U2.5 = Matches Under 2.5 Goals
- B-Y = Matches BTTS Yes
- B-No = Matches BTTS No
Napoli League Stats
Pisa League Stats
- 8 wins and 2 draws in the previous 10 matches
- 7 wins and 3 draws in the previous 10 home matches
- 4 wins, 4 defeats and 2 draws in the previous 10 matches
- 4 wins, 3 defeats and 3 draws in the previous 10 away matches
- An average of 1.70 goals scored and 0.30 conceded in the previous 10 matches
- An average of 1.80 goals scored and 0.70 conceded in the previous 10 home matches
- An average of 2.00 goals per game in the previous 10 matches
- An average of 2.50 goals per game in the previous 10 home matches
- BTTS Yes in 2 of the previous 10 matches
- BTTS Yes in 6 of the previous 10 home matches
- Over 2.5 Goals in 3 of the previous 10 matches
- Over 2.5 Goals in 5 of the previous 10 home matches
- An average of 1.20 goals scored and 1.10 conceded in the previous 10 matches
- An average of 1.30 goals scored and 0.90 conceded in the previous 10 away matches
- An average of 2.30 goals per game in the previous 10 matches
- An average of 2.20 goals per game in the previous 10 away matches
- BTTS Yes in 5 of the previous 10 matches
- BTTS Yes in 5 of the previous 10 away matches
- Over 2.5 Goals in 4 of the previous 10 matches
- Over 2.5 Goals in 4 of the previous 10 away matches
- An average of 5.40 corners awarded and 3.60 corners conceded in the last 10 matches
- An average of 6.90 corners awarded and 3.30 corners against in the last 10 home matches
- An average of 9.00 corners awarded in the last 10 matches
- An average of 10.20 corners awarded in the last 10 home matches
- Had the most corners in 5 and least corners in 4 of the last 10 matches
- Had the most corners in 5 and least corners in 2 of the last 10 home matches
- An average of 4.30 corners awarded and 5.00 corners conceded in the last 10 matches
- An average of 3.50 corners awarded and 4.40 corners against in the last 10 away matches
- An average of 9.30 corners awarded in the last 10 matches
- An average of 7.90 corners awarded in the last 10 away matches
- Had the most corners in 5 and least corners in 4 of the last 10 matches
- Had the most corners in 4 and least corners in 5 of the last 10 away matches
- An average of 61.00% possession in the last 10 matches
- An average of 58.60% possession in the last 10 home matches
- Most possession in 9 of the last 10 matches
- Most possession in 8 of the last 10 home matches
- An average of 46.70% possession in the last 10 matches
- An average of 47.80% possession in the last 10 away matches
- Most possession in 4 of the last 10 matches
- Most possession in 3 of the last 10 away matches
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Napoli vs Pisa Lineups & Team News
Be smart with your bets — check the Napoli vs Pisa team news beforehand. We’ll offer the predicted and confirmed Serie A lineups along with the latest injury developments.
Napoli Predicted Lineup 4-1-4-1
Pisa Predicted Lineup 3-5-2
Napoli Predicted Lineup 4-1-4-1
Pisa Predicted Lineup 3-5-2
Previous Napoli Lineups
Previous Pisa Lineups
Serie A Table
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Juventus | 4 | 3 | 1 | 0 | 8:4 | 10 |
| 2 | Napoli | 3 | 3 | 0 | 0 | 6:1 | 9 |
| 3 | AC Milan | 4 | 3 | 0 | 1 | 7:2 | 9 |
| 4 | Cremonese | 3 | 2 | 1 | 0 | 5:3 | 7 |
| 5 | Cagliari | 4 | 2 | 1 | 1 | 5:3 | 7 |
| 6 | Udinese | 4 | 2 | 1 | 1 | 4:5 | 7 |
| 7 | Roma | 3 | 2 | 0 | 1 | 2:1 | 6 |
| 8 | Bologna | 4 | 2 | 0 | 2 | 3:3 | 6 |
| 9 | Atalanta | 3 | 1 | 2 | 0 | 6:3 | 5 |
| 10 | Como | 3 | 1 | 1 | 1 | 3:2 | 4 |
| 11 | Torino | 3 | 1 | 1 | 1 | 1:5 | 4 |
| 12 | Inter Milan | 3 | 1 | 0 | 2 | 9:6 | 3 |
| 13 | Lazio | 3 | 1 | 0 | 2 | 4:3 | 3 |
| 14 | Sassuolo | 3 | 1 | 0 | 2 | 3:5 | 3 |
| 15 | Hellas Verona | 4 | 0 | 3 | 1 | 2:6 | 3 |
| 16 | Fiorentina | 3 | 0 | 2 | 1 | 2:4 | 2 |
| 17 | Genoa | 4 | 0 | 2 | 2 | 2:4 | 2 |
| 18 | Pisa | 3 | 0 | 1 | 2 | 1:3 | 1 |
| 19 | Parma | 3 | 0 | 1 | 2 | 1:5 | 1 |
| 20 | Lecce | 4 | 0 | 1 | 3 | 2:8 | 1 |
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Juventus | 2 | 2 | 0 | 0 | 6:3 | 6 |
| 2 | Bologna | 2 | 2 | 0 | 0 | 3:1 | 6 |
| 3 | Atalanta | 2 | 1 | 1 | 0 | 5:2 | 4 |
| 4 | Cagliari | 2 | 1 | 1 | 0 | 3:1 | 4 |
| 5 | Como | 2 | 1 | 1 | 0 | 3:1 | 4 |
| 6 | Inter Milan | 2 | 1 | 0 | 1 | 6:2 | 3 |
| 7 | Lazio | 1 | 1 | 0 | 0 | 4:0 | 3 |
| 8 | Cremonese | 1 | 1 | 0 | 0 | 3:2 | 3 |
| 9 | Napoli | 1 | 1 | 0 | 0 | 1:0 | 3 |
| 10 | AC Milan | 2 | 1 | 0 | 1 | 2:2 | 3 |
| 11 | Roma | 2 | 1 | 0 | 1 | 1:1 | 3 |
| 12 | Sassuolo | 2 | 1 | 0 | 1 | 1:2 | 3 |
| 13 | Hellas Verona | 2 | 0 | 2 | 0 | 1:1 | 2 |
| 14 | Parma | 1 | 0 | 1 | 0 | 1:1 | 1 |
| 15 | Torino | 1 | 0 | 1 | 0 | 0:0 | 1 |
| 16 | Genoa | 2 | 0 | 1 | 1 | 0:1 | 1 |
| 17 | Udinese | 2 | 0 | 1 | 1 | 1:4 | 1 |
| 18 | Fiorentina | 1 | 0 | 0 | 1 | 1:3 | 0 |
| 19 | Pisa | 2 | 0 | 0 | 2 | 0:2 | 0 |
| 20 | Lecce | 2 | 0 | 0 | 2 | 1:4 | 0 |
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