PSV vs Napoli Prediction, Betting Tips, Lineups & Odds | 21 Oct 2025

Champions League Betting Preview: PSV vs Napoli

Dutch Eredivisie outfit PSV host Italian Serie A club Napoli in this Champions League match at Philips Stadion, with kick-off set for 15:00 on Tuesday 21 October. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

Goals could be the order of the day when PSV clash with Napoli and we’ll wager on the Total Goals market. Bettors can secure -161 that Over 2.5 happens and that price looks like a spot of value.

Going with our Total Goals selection? Make sure you’ve got the BetMGM promo code locked in and our review read through.

PSV Eindhoven were winners last time out. Landing a 2-1 Eredivisie home triumph against Go Ahead Eagles at Philips Stadion. Peter Bosz's side had most of the ball boasting 57% possession and eight shots on target, with Guus Til scoring both goals.

Napoli were defeated in their previous game. On their travels, they suffered a 1-0 Serie A loss against Torino at Stadio Olimpico Grande Torino. Gli Azzurri dominated possession with 69% of the ball and racked up five shots on goal.

When last playing in the Champions League, PSV visited Bayer Leverkusen and drew 1-1, with Napoli winning 2-1 at home to Sporting CP.

Champions League		G	W	D	L	GF	GA	GD	GD	P
28	PSV	8	2	2	4	16	16	0	16:16	8
30	Napoli	8	2	2	4	9	15	-6	9:15	8

View Full Table

PSV have 8 wins, 1 loss and 1 draw, averaging 3.0 goals from 8.0 shots on goal and 19.3 attempts. The Peasants have averaged 62.0% possession, 555.0 passes and 6.8 corners per match, with their opponents getting 1.3 goals from 3.7 shots on goal, 10.8 attempts and 4.1 corners.

Top goalscorers Guus Til and Joey Veerman have found the net 4 times, with Ismael Saibari scoring 3. Ivan Perisic is the leading assists maker on 5, with goalkeeper Matej Kovar keeping 2 clean sheets.

Napoli have 6 victories, 2 defeats and 2 draws, with an average of 6.0 shots on goal, 16.9 attempts and 1.6 goals. Antonio Conte's men average 64.0% possession, 559.4 passes, 6.8 corners taken and 2.7 corners against them, while 0.9 goals have been conceded from 8.6 attempts and 2.5 shots on goal.

Kevin De Bruyne is top of the team’s scoring charts with 3, while Andre-Frank Zambo Anguissa, Rasmus Hoejlund, Scott McTominay and Romelu Lukaku have 2. Scott McTominay has clocked up 3 assists, with Alex Meret keeping 4 clean sheets in the last 10 games.

Confirmed Lineups

PSV confirmed lineup (4-2-3-1): Matej Kovar (GK), Ryan Flamingo, Jerdy Schouten, Yarek Gasiorowski, Anass Salah-Eddine, Mauro Junior, Joey Veerman, Dennis Man, Ismael Saibari, Ivan Perisic, Guus Til.

Napoli confirmed lineup (4-1-4-1): Vanja Milinkovic-Savic (GK), Giovanni Di Lorenzo, Sam Beukema, Alessandro Buongiorno, Leonardo Spinazzola, Billy Gilmour, Matteo Politano, Andre-Frank Zambo Anguissa, Kevin De Bruyne, Scott McTominay, Lorenzo Lucca.

PSV vs Napoli Prediction & Betting Tips

This expert PSV vs Napoli betting breakdown features our match prediction, a correct score tip, corners analysis, player prop suggestions and a carefully constructed bet builder to guide your wagers.

Match Prediction

We could see the ball hit the net a few times in this Champions League clash, so let’s take the -161 when it comes to Over 2.5. We’re confident of a return based on the available information.

We study the Champions League form as a first port of call and also make sure we’re across any injuries before making our football predictions. Then it’s a case of understanding the sort of narrative that the stats provide.

Key PSV vs Napoli Champions League & league stats:

• The 2.5 line has been covered in 17 of the last 20 PSV games at home.
• The 2.5 line has been covered in 8 of the last 10 PSV games at home.
• The 2.5 line has been covered in the last 3 PSV games at home.
• The 2.5 line has been covered in 4 of the last 5 Napoli games.

The betting apps are estimating that there is a 61.7% likelihood of this pick landing a return. However, our experts think that the probability sits between 65-70% taking all factors into consideration. The wager can be recommended for this precise reason.

If you’re looking for bigger odds, then consider combining Over 2.5 Goals with other selections. This can be achieved by placing a Bet Builder and there’s some tasty prices available.

Claim bonuses and free bets before placing a wager. Our in-depth guide shows you the best current betting offers.

Our Match Prediction

Over 2.5 Goals @ -161 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (21:08, 19 October 2025). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

PSV 1 - 2 Napoli

Our prediction for the correct score is Napoli to land a 2-1 victory and this is available at +750. It’s a fun wager to place which lands a bigger potential return.

Player Prop Picks

Top Pick: Scott McTominay Over 0.5 Shots On Target -161

Scott McTominay (Napoli) has bagged at least one shot on goal in seven of his past nine games away from home. The numbers imply that he can succeed with our Overs bet and we’re delighted to take the -161 available.

Latest Scott McTominay Player Prop Odds

Goalscorer

Anytime

+250

First

+600

Shots On Target

Over 0.5

-149

Under 0.5

-105

Shots

Over 1.5

-179

Under 1.5

-

---

Kevin De Bruyne to Score +260

Kevin De Bruyne (Napoli) has netted three goals in his past five matches away from home. When it comes to him scoring, we think that the +260 available is attractive when betting on the Anytime Goalscorer market.

Latest Kevin De Bruyne Player Prop Odds

Goalscorer

Anytime

+270

First

+600

Shots On Target

Over 0.5

-161

Under 0.5

+104

Shots

Over 2.5

+105

Under 2.5

-

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Corners Prediction

PSV Over 4.5 Corners -133

PSV have covered the 4.5 corners line in ten consecutive home matches. The PSV Team Corners line looks attractive and we’re going to take the -133 that it’s covered.

Champions League & League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

PSV

Total

11.20 6.20 5.00

Home

11.10 7.70 3.40

Away

9.90 6.00 3.90

Napoli

Total

10.20 6.70 3.50

Home

9.40 6.10 3.30

Away

9.60 4.90 4.70

Latest Corner Odds

Total Corners

Over 9.5

-106

Under 9.5

-133

PSV Corners

Over 4.5

+102

Under 4.5

-147

Napoli Corners

Over 4.5

-137

Under 4.5

-103

Most Corners

1

+133

X

+600

2

-116

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

PSV vs Napoli Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

You can get betting odds of +132 for Napoli winning this Champions League clash and the bookies have PSV Eindhoven available at +195. If you want to back the draw, it’s on offer at +255.

A win for Napoli would see a full payout on the Asian Handicap -0.25 option. You can get -102 that they overcome PSV going down this route and half stake refunded if it’s a draw.

The Total Goals market reveals that Over 2.5 Goals is the current betting favourite. If you are expecting both teams to score, there’s the chance to back Yes at -182 on the BTTS market.

The leading football betting sites provide bettors with an abundance of options. For every Champions League match, you’re able to select from hundreds of markets and make the best choice.

Full-Time Result

1

+195

X

+255

2

+132

Half-Time Result

1

+235

X

+138

2

+175

Double Chance

1X

-167

12

-345

X2

-263

Draw No Bet

1

+108

2

-149

Asian Handicap

1 Hcp +0.25

-123

2 Hcp -0.25

-102

Total Goals

Under 2.5

+120

Over 2.5

-149

Both Teams to Score

Yes

-182

No

+140

Lorenzo Lucca is available at +155 when it comes to Anytime Goalscorer, with the favourite priced at odds of +390 to find the net first.

Lorenzo Lucca (Napoli)

First

+155

Anytime

+390

Ricardo Pepi (PSV)

First

+205

Anytime

+525

Scott McTominay (Napoli)

First

+250

Anytime

+600

Rasmus Højlund (Napoli)

First

+270

Anytime

+600

Kevin De Bruyne (Napoli)

First

+270

Anytime

+600

Ivan Perisic (PSV)

First

+270

Anytime

+650

Myron Boadu (PSV)

First

+310

Anytime

+750

Ismael Saibari (PSV)

First

+330

Anytime

+850

Noa Lang (Napoli)

First

+350

Anytime

+850

Guus Til (PSV)

First

+350

Anytime

+950

Eljif Elmas (Napoli)

First

+360

Anytime

+950

Couhaib Driouech (PSV)

First

+390

Anytime

+950

Esmir Bajraktarevic (PSV)

First

+400

Anytime

+950

Dennis Man (PSV)

First

+400

Anytime

+1000

Paul Wanner (PSV)

First

+400

Anytime

+1100

Matteo Politano (Napoli)

First

+440

Anytime

+1150

Frank Anguissa (Napoli)

First

+525

Anytime

+1400

Miguel Gutiérrez (Napoli)

First

+525

Anytime

+1400

Joey Veerman (PSV)

First

+650

Anytime

+1600

Mauro Jaqueson Júnior Ferreira dos Santos (PSV)

First

+850

Anytime

+2000

Billy Gilmour (Napoli)

First

+900

Anytime

+2200

Lorenzo Lucca (Napoli)

Over 0.5

-250

Under 0.5

+143

Ricardo Pepi (PSV)

Over 0.5

-192

Under 0.5

+120

Kevin De Bruyne (Napoli)

Over 0.5

-161

Under 0.5

+104

Scott McTominay (Napoli)

Over 0.5

-149

Under 0.5

-105

Ivan Perisic (PSV)

Over 0.5

-137

Under 0.5

-115

Rasmus Højlund (Napoli)

Over 0.5

-133

Under 0.5

-116

Ismael Saibari (PSV)

Over 0.5

-130

Under 0.5

-119

Myron Boadu (PSV)

Over 0.5

-114

Under 0.5

-137

Noa Lang (Napoli)

Over 0.5

+108

Under 0.5

-189

Guus Til (PSV)

Over 0.5

+115

Under 0.5

-182

Eljif Elmas (Napoli)

Over 0.5

+120

Under 0.5

-200

Couhaib Driouech (PSV)

Over 0.5

+125

Under 0.5

-200

Dennis Man (PSV)

Over 0.5

+130

Under 0.5

-213

Paul Wanner (PSV)

Over 0.5

+130

Under 0.5

-208

Esmir Bajraktarevic (PSV)

Over 0.5

+135

Under 0.5

-217

Matteo Politano (Napoli)

Over 0.5

+155

Under 0.5

-250

Frank Anguissa (Napoli)

Over 0.5

+175

Under 0.5

-294

Miguel Gutiérrez (Napoli)

Over 0.5

+190

Under 0.5

-333

Joey Veerman (PSV)

Over 0.5

+215

Under 0.5

-385

Mauro Jaqueson Júnior Ferreira dos Santos (PSV)

Over 0.5

+320

Under 0.5

-667

Billy Gilmour (Napoli)

Over 0.5

+340

Under 0.5

-769

Lorenzo Lucca (Napoli)

Over 3.5

+117

Under 3.5

-

Rasmus Højlund (Napoli)

Over 2.5

+145

Under 2.5

-

Kevin De Bruyne (Napoli)

Over 2.5

+105

Under 2.5

-

Matteo Politano (Napoli)

Over 2.5

+135

Under 2.5

-

Ismael Saibari (PSV)

Over 2.5

-147

Under 2.5

-

Ricardo Pepi (PSV)

Over 2.5

-102

Under 2.5

-

Esmir Bajraktarevic (PSV)

Over 1.5

+110

Under 1.5

-

Frank Anguissa (Napoli)

Over 1.5

-152

Under 1.5

-

Paul Wanner (PSV)

Over 1.5

+115

Under 1.5

-

Dennis Man (PSV)

Over 1.5

+112

Under 1.5

-

Guus Til (PSV)

Over 1.5

-112

Under 1.5

-

Couhaib Driouech (PSV)

Over 1.5

+115

Under 1.5

-

Eljif Elmas (Napoli)

Over 1.5

-118

Under 1.5

-

Noa Lang (Napoli)

Over 1.5

-143

Under 1.5

-

Myron Boadu (PSV)

Over 1.5

-154

Under 1.5

-

Ivan Perisic (PSV)

Over 1.5

-175

Under 1.5

-

Scott McTominay (Napoli)

Over 1.5

-179

Under 1.5

-

Joey Veerman (PSV)

Over 1.5

+130

Under 1.5

-

Miguel Gutiérrez (Napoli)

Over 0.5

-263

Under 0.5

-

Latest Champions League and domestic league stats. Full Time Result, Goals, Corners and Possession.

PSV Stats

Napoli Stats

Full-Time Result

• 8 wins, 1 defeat and 1 draw in the previous 10 matches
• 7 wins, 2 defeats and 1 draw in the previous 10 home matches

Full-Time Result

• 6 wins, 2 defeats and 2 draws in the previous 10 matches
• 4 wins, 3 defeats and 3 draws in the previous 10 away matches

Goals

• An average of 3.00 goals scored and 1.30 conceded in the previous 10 matches
• An average of 2.90 goals scored and 1.30 conceded in the previous 10 home matches
• An average of 4.30 goals per game in the previous 10 matches
• An average of 4.20 goals per game in the previous 10 home matches
• BTTS Yes in 7 of the previous 10 matches
• BTTS Yes in 7 of the previous 10 home matches
• Over 2.5 Goals in 8 of the previous 10 matches
• Over 2.5 Goals in 8 of the previous 10 home matches

Goals

• An average of 1.60 goals scored and 0.90 conceded in the previous 10 matches
• An average of 1.00 goals scored and 0.70 conceded in the previous 10 away matches
• An average of 2.50 goals per game in the previous 10 matches
• An average of 1.70 goals per game in the previous 10 away matches
• BTTS Yes in 5 of the previous 10 matches
• BTTS Yes in 4 of the previous 10 away matches
• Over 2.5 Goals in 5 of the previous 10 matches
• Over 2.5 Goals in 3 of the previous 10 away matches

Corners

• An average of 6.80 corners awarded and 4.10 corners conceded in the last 10 matches
• An average of 7.80 corners awarded and 3.10 corners against in the last 10 home matches
• An average of 10.90 corners awarded in the last 10 matches
• An average of 10.90 corners awarded in the last 10 home matches
• Had the most corners in 7 and least corners in 3 of the last 10 matches
• Had the most corners in 10 and least corners in 0 of the last 10 home matches

Corners

• An average of 6.80 corners awarded and 2.70 corners conceded in the last 10 matches
• An average of 5.30 corners awarded and 4.20 corners against in the last 10 away matches
• An average of 9.50 corners awarded in the last 10 matches
• An average of 9.50 corners awarded in the last 10 away matches
• Had the most corners in 8 and least corners in 2 of the last 10 matches
• Had the most corners in 6 and least corners in 4 of the last 10 away matches

Possession

• An average of 62.00% possession in the last 10 matches
• An average of 65.80% possession in the last 10 home matches
• Most possession in 8 of the last 10 matches
• Most possession in 10 of the last 10 home matches

Possession

• An average of 64.00% possession in the last 10 matches
• An average of 58.00% possession in the last 10 away matches
• Most possession in 9 of the last 10 matches
• Most possession in 8 of the last 10 away matches

PSV vs Napoli Lineups & Team News

Know who’s in and who’s out for PSV vs Napoli before making your bets. We’ll keep you posted with predicted and confirmed lineups for the Champions League and all current injury news.

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