Real Betis vs Lyon Prediction, Betting Tips, Lineups & Odds | 06 Nov 2025

Europa League Betting Preview: Real Betis vs Lyon

Spanish La Liga side Real Betis host French Ligue 1 outfit Lyon in this Europa League match at Estadio de La Cartuja, with kick-off set for 15:00 on Thursday 6 November. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

Betis can’t be ignored when they meet Lyon, especially as betting odds of -122 are available for this prediction. Head to the Full-Time Result market to back this value selection.

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Real Betis won their last game, triumphing 3-0 at Estadio de La Cartuja against Mallorca in La Liga. Los Verdiblancos managed eight shots on target and had 52% possession, while Antony scored two goals and Abdessamad Ezzalzouli registered the other.

Lyon played Brest on the road in their previous game. It was a 0-0 Ligue 1 draw at Stade Francis-Le Blé. Paulo Fonseca's team had 51% possession and managed one shot on goal.

In the last Europa League round, Betis were held to a 0-0 draw away to Genk, while Lyon hosted FC Basel and won 2-0.

Europa League		G	W	D	L	GF	GA	GD	GD	P
1	Lyon	8	7	0	1	18	5	13	18:5	21
4	Real Betis	8	5	2	1	13	7	6	13:7	17

View Full Table

5 wins, 1 loss and 4 draws, averaging 1.8 goals from 5.0 shots on goal and 13.7 attempts. Betis have had 54.6% possession and 4.6 corners per match. On average, the opposition have scored 1.0 goals from 2.9 shots on goal and 9.2 attempts, while being awarded 4.9 corners.

Antony leads the way with 5 goals, while Juan Hernandez and Abdessamad Ezzalzouli have 4 and 3 respectively. Pablo Fornals is the top assists maker on 4, with goalkeepers Pau Lopez and Alvaro Valles managing 2 clean sheets between them.

Lyon have 6 victories, 2 defeats and 2 draws, averaging 11.0 attempts, 4.0 shots on goal and 1.5 goals. The Auvergne-Rhône-Alpes side average 58.1% possession, 5.4 corners awarded and 3.8 corners against them, while 0.9 goals have been conceded from 3.2 shots on goal and 9.0 attempts.

Pavel Sulc has top scored with 4, while Corentin Tolisso, Afonso Moreira and Tanner Tessmann are next on 2. Afonso Moreira and Adam Karabec have clocked up 2 assists, with Dominik Greif keeping 3 clean sheets in the last 10 games.

Confirmed Lineups

Real Betis confirmed lineup (4-2-3-1): Alvaro Valles (GK), Aitor Ruibal, Diego Llorente, Natan, Valentin Gomez, Pablo Fornals, Marc Roca, Antony, Giovani Lo Celso, Abdessamad Ezzalzouli, Cedric Bakambu.

Lyon confirmed lineup (4-2-3-1): Dominik Greif (GK), Ainsley Maitland-Niles, Ruben Kluivert, Moussa Niakhate, Abner, Tanner Tessmann, Mathys de Carvalho, Adam Karabec, Khalis Merah, Enzo Molebe, Martin Satriano.

Real Betis vs Lyon Prediction & Betting Tips

This Real Betis vs Lyon betting breakdown features a main match prediction, a correct score insight, expert player prop picks, corners analysis and a sharply constructed bet builder to guide your wagers.

Match Prediction

There’s every chance that Betis can get the upper hand in this Europa League game and we’ll therefore back the hosts to claim a victory. The match winner odds of -122 look too good to resist.

The football experts at Sportsgambler.com check injury updates regularly and combine this with the form guide. We’re also able to consult a database of Europa League stats and present the key numbers to our readers.

Key Real Betis vs Lyon Europa League & league stats:

• Betis have won 3 of their last 5 games at home.

The latest betting odds imply that our pick has a 54.9% prospect of winning. After careful examination, our tipsters have this probability close to 60%. This bet can therefore be backed with confidence.

If you want to pimp the odds about Betis to win on the Full-Time Result market, you might consider going down the Bet Builder route and combine this pick with other selections.

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Our Match Prediction

Betis To Win @ -122 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (21:08, 04 November 2025). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Betis 2 - 1 Lyon

A 2-1 win in favor of Betis can be backed at odds of +650. We like placing a bet on correct score due to the fun element and the big potential return.

Player Prop Picks

Top Pick: Abde Ezzalzouli Over 0.5 Shots On Target -109

Abde Ezzalzouli (Betis) has racked up at least one shot on goal in back-to-back games. We are in favour of betting the -109 that he is able to cover the line, with this Shots on Target wager looking like it might yield dividends.

Latest Abde Ezzalzouli Player Prop Odds

Goalscorer

Anytime

+270

First

+700

Shots On Target

Over 0.5

-122

Under 0.5

-139

Shots

Over 2.5

-120

Under 2.5

-

---

Pablo Fornals to Score +575

Pablo Fornals (Betis) has scored two goals in his past ten games. We’ll throw a dart at +575 for this Anytime Goalscorer wager as the betting odds look pretty attractive.

Latest Pablo Fornals Player Prop Odds

Goalscorer

Anytime

+550

First

+1500

Shots On Target

Over 0.5

+230

Under 0.5

-500

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Corners Prediction

Under 9.5 Corners -100

It’s been three straight Real Betis games where the 9.5 Total Corners line has not been covered, with the same thing happening in six of the past ten Lyon matches. There’s the opportunity to go under the Total Corners line and we’re expecting this to happen, with odds of -100 on offer.

Europa League & League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Betis

Total

9.50 4.60 4.90

Home

8.70 4.00 4.70

Away

11.20 5.40 5.80

Lyon

Total

9.20 5.40 3.80

Home

9.40 6.10 3.30

Away

11.50 5.50 6.00

Latest Corner Odds

Total Corners

Over 9.5

-149

Under 9.5

+105

Betis Corners

Over 5.5

-139

Under 5.5

-102

Lyon Corners

Over 3.5

-154

Under 3.5

+108

Most Corners

1

-213

X

+700

2

+230

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Real Betis vs Lyon Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Real Betis are forecasted to be the most likely winner in this Europa League encounter. The -167 for them coming out on top suggests a 63% probability based on their latest betting odds. Lyon are the +420 outsiders, with the draw being a different option which could yield dividends.

The Over 2.5 option is currently favourite on the Total Goals betting market. If you think both teams will score, then you can back BTTS Yes at -143.

You’ll be blown away by the hundreds of markets available for Europa League games. Head to one of our recommended betting sites and take your pick from the various football options available.

Full-Time Result

1

-167

X

+320

2

+420

Half-Time Result

1

+110

X

+143

2

+380

Double Chance

1X

-625

12

-455

X2

+125

Draw No Bet

1

-417

2

+270

Asian Handicap

1 Hcp -1

-100

2 Hcp +1

-123

Total Goals

Under 2.5

+120

Over 2.5

-154

Both Teams to Score

Yes

-143

No

+107

Favourite Antony Matheus dos Santos is priced at +390 to be the first player to find the net. There’s also the opportunity to back him to score any time at odds of +138.

Antony Matheus dos Santos (Betis)

First

+138

Anytime

+390

Cucho Hernández (Betis)

First

+148

Anytime

+390

Cédric Bakambu (Betis)

First

+180

Anytime

+480

Giovani Lo Celso (Betis)

First

+215

Anytime

+575

Abde Ezzalzouli (Betis)

First

+270

Anytime

+700

Corentin Tolisso (OL)

First

+330

Anytime

+900

Alejandro Jesús Gomes Rodríguez (OL)

First

+340

Anytime

+800

Chimy Ávila (Betis)

First

+360

Anytime

+900

Nelson Alexander Deossa (Betis)

First

+360

Anytime

+950

Rodrigo Riquelme (Betis)

First

+380

Anytime

+1000

Martín Satriano (OL)

First

+400

Anytime

+900

Aitor Ruibal (Betis)

First

+410

Anytime

+1100

Afonso Bastardo Moreira (OL)

First

+425

Anytime

+1050

Pavel Sulc (OL)

First

+440

Anytime

+1200

Enzo Molébé (OL)

First

+480

Anytime

+1150

Pablo Fornals (Betis)

First

+550

Anytime

+1500

Sergi Altimira (Betis)

First

+550

Anytime

+1500

Adam Karabec (OL)

First

+700

Anytime

+1700

Khalis Merah (OL)

First

+700

Anytime

+1900

Marc Roca (Betis)

First

+800

Anytime

+2000

Tanner Tessmann (OL)

First

+800

Anytime

+2200

Ainsley Maitland-Niles (OL)

First

+800

Anytime

+2200

Mathys de Carvalho Soares (OL)

First

+850

Anytime

+2200

Tyler Morton (OL)

First

+850

Anytime

+2200

Cucho Hernández (Betis)

Over 0.5

-294

Under 0.5

+160

Antony Matheus dos Santos (Betis)

Over 0.5

-270

Under 0.5

+155

Cédric Bakambu (Betis)

Over 0.5

-204

Under 0.5

+120

Giovani Lo Celso (Betis)

Over 0.5

-167

Under 0.5

-102

Abde Ezzalzouli (Betis)

Over 0.5

-122

Under 0.5

-139

Corentin Tolisso (OL)

Over 0.5

-104

Under 0.5

-164

Alejandro Jesús Gomes Rodríguez (OL)

Over 0.5

-103

Under 0.5

-167

Chimy Ávila (Betis)

Over 0.5

+123

Under 0.5

-213

Nelson Alexander Deossa (Betis)

Over 0.5

+123

Under 0.5

-213

Martín Satriano (OL)

Over 0.5

+123

Under 0.5

-217

Afonso Bastardo Moreira (OL)

Over 0.5

+135

Under 0.5

-238

Pavel Sulc (OL)

Over 0.5

+135

Under 0.5

-238

Rodrigo Riquelme (Betis)

Over 0.5

+150

Under 0.5

-263

Enzo Molébé (OL)

Over 0.5

+160

Under 0.5

-286

Aitor Ruibal (Betis)

Over 0.5

+165

Under 0.5

-313

Adam Karabec (OL)

Over 0.5

+200

Under 0.5

-385

Pablo Fornals (Betis)

Over 0.5

+230

Under 0.5

-500

Sergi Altimira (Betis)

Over 0.5

+230

Under 0.5

-476

Khalis Merah (OL)

Over 0.5

+250

Under 0.5

-526

Tanner Tessmann (OL)

Over 0.5

+270

Under 0.5

-625

Ainsley Maitland-Niles (OL)

Over 0.5

+300

Under 0.5

-714

Mathys de Carvalho Soares (OL)

Over 0.5

+320

Under 0.5

-909

Antony Matheus dos Santos (Betis)

Over 3.5

-122

Under 3.5

-

Cucho Hernández (Betis)

Over 3.5

-104

Under 3.5

-

Cédric Bakambu (Betis)

Over 2.5

-102

Under 2.5

-

Giovani Lo Celso (Betis)

Over 2.5

+128

Under 2.5

-

Abde Ezzalzouli (Betis)

Over 2.5

-120

Under 2.5

-

Corentin Tolisso (OL)

Over 1.5

-161

Under 1.5

-

Alejandro Jesús Gomes Rodríguez (OL)

Over 1.5

+108

Under 1.5

-

Nelson Alexander Deossa (Betis)

Over 1.5

-104

Under 1.5

-

Martín Satriano (OL)

Over 1.5

-125

Under 1.5

-

Afonso Bastardo Moreira (OL)

Over 1.5

-102

Under 1.5

-

Pavel Sulc (OL)

Over 1.5

+105

Under 1.5

-

Enzo Molébé (OL)

Over 1.5

+125

Under 1.5

-

Aitor Ruibal (Betis)

Over 0.5

-250

Under 0.5

-

Adam Karabec (OL)

Over 0.5

-250

Under 0.5

-

Khalis Merah (OL)

Over 0.5

-179

Under 0.5

-

Tanner Tessmann (OL)

Over 0.5

-200

Under 0.5

-

Latest Europa League and domestic league stats. Full Time Result, Goals, Corners and Possession.

Real Betis Stats

Lyon Stats

Full-Time Result

• 5 wins, 1 defeat and 4 draws in the previous 10 matches
• 5 wins, 2 defeats and 3 draws in the previous 10 home matches

Full-Time Result

• 6 wins, 2 defeats and 2 draws in the previous 10 matches
• 3 wins, 5 defeats and 2 draws in the previous 10 away matches

Goals

• An average of 1.80 goals scored and 1.00 conceded in the previous 10 matches
• An average of 1.90 goals scored and 1.00 conceded in the previous 10 home matches
• An average of 2.80 goals per game in the previous 10 matches
• An average of 2.90 goals per game in the previous 10 home matches
• BTTS Yes in 5 of the previous 10 matches
• BTTS Yes in 6 of the previous 10 home matches
• Over 2.5 Goals in 6 of the previous 10 matches
• Over 2.5 Goals in 5 of the previous 10 home matches

Goals

• An average of 1.50 goals scored and 0.90 conceded in the previous 10 matches
• An average of 1.40 goals scored and 1.80 conceded in the previous 10 away matches
• An average of 2.40 goals per game in the previous 10 matches
• An average of 3.20 goals per game in the previous 10 away matches
• BTTS Yes in 4 of the previous 10 matches
• BTTS Yes in 5 of the previous 10 away matches
• Over 2.5 Goals in 4 of the previous 10 matches
• Over 2.5 Goals in 5 of the previous 10 away matches

Corners

• An average of 4.60 corners awarded and 4.90 corners conceded in the last 10 matches
• An average of 4.00 corners awarded and 4.70 corners against in the last 10 home matches
• An average of 9.50 corners awarded in the last 10 matches
• An average of 8.70 corners awarded in the last 10 home matches
• Had the most corners in 2 and least corners in 6 of the last 10 matches
• Had the most corners in 2 and least corners in 5 of the last 10 home matches

Corners

• An average of 5.40 corners awarded and 3.80 corners conceded in the last 10 matches
• An average of 5.50 corners awarded and 6.00 corners against in the last 10 away matches
• An average of 9.20 corners awarded in the last 10 matches
• An average of 11.50 corners awarded in the last 10 away matches
• Had the most corners in 8 and least corners in 2 of the last 10 matches
• Had the most corners in 4 and least corners in 6 of the last 10 away matches

Possession

• An average of 54.60% possession in the last 10 matches
• An average of 53.80% possession in the last 10 home matches
• Most possession in 7 of the last 10 matches
• Most possession in 7 of the last 10 home matches

Possession

• An average of 58.10% possession in the last 10 matches
• An average of 53.40% possession in the last 10 away matches
• Most possession in 7 of the last 10 matches
• Most possession in 6 of the last 10 away matches

Real Betis vs Lyon Lineups & Team News

Make sure to look over the Betis vs OL team news before betting. Get the latest predicted and confirmed Europa League lineups and injury news right here.

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