Santa Fe vs Atlético Nacional Prediction, Betting Tips & Odds | 25 Feb 2026

Primera A Betting Preview: Santa Fe vs Atlético Nacional

Santa Fe take on Atlético Nacional, with kick-off set for 19:00 on Wednesday 25 February.

When Santa Fe meet Atlético Nacional, we will back the hosts at -147 on the Asian Handicap +0.25. With the stake split between 0 and +0.5, they look capable of landing a return by avoiding defeat.

Santa Fe landed a 2-1 win last time out, beating Junior at home.

Atlético Nacional won their previous game, beating Alianza Petrolera at home. It was a 3-0 victory.

Head-to-Head Statistics

The last time Nacional and Santa Fe met involved the former hosting a 1-1 draw. We’ve seen the previous 10 H2H matches involve five Nacional victories. There have also been four draws and Santa Fe triumphing once.

Categoria Primera A		G	W	D	L	GF	GA	GD	GD	P
5	Atlético Nacional	5	4	0	1	13	3	10	13:3	12
12	Santa Fe	8	2	4	2	9	10	-1	9:10	10

View Full Table

Santa Fe vs Atlético Nacional Prediction & Betting Tips

Step into Santa Fe vs Atlético Nacional with confidence, armed with our expert match prediction, likely scoreline, key player prop plays and a custom-built bet builder for maximum value.

Match Prediction

Santa Fe +0.25 look like a value bet on the Asian Handicap. We think that the hosts have a good chance of recording a win in this Primera A game and it’s therefore a confident selection at -147.

Injuries and suspensions are taken into account by the Primera A experts at Sportsgambler.com. Our football betting tips are also shaped by the latest form, with the stats playing a big part before predictions are made.

Key Santa Fe vs Atlético Nacional league stats:

• The +0.25 line has been covered by Santa Fe in 4 consecutive games at home.
• The +0.25 line has been covered by Santa Fe in 8 of their last 10 games.
• The +0.25 line has been covered by Santa Fe in 14 of their last 20 games.
• The -0.25 line hasn’t been covered by Nacional in 5 consecutive games on the road.
• The -0.25 line hasn’t been covered by Nacional in 8 of their last 10 games on the road.
• The -0.25 line hasn’t been covered by Nacional in 15 of their last 20 games on the road.

The odds at the best football bookies suggest our pick has a 59.5% chance of winning. After careful examination, our tipsters calculate this probability to be somewhere between 65-70%. That means we’re regarding it as a value bet.

If you’re searching for a larger price, then there’s the opportunity to move the line. Select from a host of choices and get paid out if your selection lands.

Don’t miss out on extra value. Our comprehensive guide features a wide range of free bets and sign-up bonuses for new bettors.

Our Match Prediction

Santa Fe Asian Hcp +0.25 @ -147 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Feb 24, 01:27). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Santa Fe 1 - 0 Nacional

There’s plenty of juice to be found by backing Santa Fe to win 1-0. We can’t pass up the odds of +550 when it comes to correct score betting and it’s a fun wager.

Player Prop Picks

Top Pick: Jorge Ramos To Score +300

Jorge Ramos (Santa Fe) is available to be on the scoresheet at +300. The Anytime Goalscorer odds look really appealing considering all angles and we’ll take a chance on him.

Latest Jorge Ramos Player Prop Odds

Goalscorer

Anytime

+300

First

+600

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Santa Fe vs Atlético Nacional Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The draw is available at +190 if you believe that this Primera A clash will finish level, with Atlético Nacional at +140 and Santa Fe chalked up at +200 with the bookmakers to secure a win of their own.

If you fancy Nacional but want money back if the game ends in a draw, then you can secure odds of -152. Alternatively, there’s the chance to wager on Santa Fe at +105 on the Draw No Bet market.

A low-scoring contest will be predicted by several which is reflected in the fact that Under 2.5 Goals has the shortest odds. Both Teams to Score is a two-way market and, in terms of price, there’s not much to split Yes and No.

There are hundreds of markets when it comes to betting on the Primera A coupon and we recommend visiting the best betting sites to find the football wager that matches your view on the game.

Full-Time Result

1

+200

X

+190

2

+140

Half-Time Result

1

+245

X

+108

2

+200

Double Chance

1X

-213

12

-294

X2

-313

Draw No Bet

1

+105

2

-152

Asian Handicap

1 Hcp +0.25

-147

2 Hcp -0.25

-100

Total Goals

Under 2.5

-164

Over 2.5

+120

Both Teams to Score

Yes

-123

No

-116

Those interested in favourite Hugo Rodallega to find the net first can get +360, while the Anytime Goalscorer angle could hold more appeal and this is +175.

Hugo Rodallega (Santa Fe)

First

+175

Anytime

+360

Cristian Arango (Nacional)

First

+185

Anytime

+400

Alfredo Morelos (Nacional)

First

+188

Anytime

+400

Jorge Ramos (Santa Fe)

First

+300

Anytime

+600

Edwin Cardona (Nacional)

First

+340

Anytime

+700

Juan Rengifo (Nacional)

First

+375

Anytime

+700

Nahuel Bustos (Santa Fe)

First

+375

Anytime

+750

Eduard Bello (Nacional)

First

+460

Anytime

+950

Edwin Mosquera (Santa Fe)

First

+525

Anytime

+1100

Nicolás Rodríguez (Nacional)

First

+540

Anytime

+1000

Dairon Asprilla (Nacional)

First

+600

Anytime

+1200

Andres Sarmiento (Nacional)

First

+600

Anytime

+1200

Luis Angel Palacios (Santa Fe)

First

+650

Anytime

+1300

Christian Mafla (Santa Fe)

First

+700

Anytime

+1500

Yilmar Andres Velasquez (Santa Fe)

First

+750

Anytime

+1500

Samuel Velásquez (Nacional)

First

+750

Anytime

+1600

Alexis Zapata (Santa Fe)

First

+800

Anytime

+1700

Kilian Toscano (Santa Fe)

First

+900

Anytime

+1900

Daniel Torres (Santa Fe)

First

+950

Anytime

+2000

Yeicar Alberto Perlaza Perea (Santa Fe)

First

+950

Anytime

+2000

Jhojan Torres (Santa Fe)

First

+950

Anytime

+2000

Omar Fernandez (Santa Fe)

First

+1000

Anytime

+2000

Mateus Uribe (Nacional)

First

+1050

Anytime

+2000

Jhon Melendez (Santa Fe)

First

+1050

Anytime

+2200

Andrés Felipe Román (Nacional)

First

+1050

Anytime

+2200

Santa Fe vs Atlético Nacional Lineups & Team News

Make sure to look over the Santa Fe vs Nacional team news before betting. Stay in the know with the confirmed Primera A lineups and up-to-date injury news.

Santa Fe Team Page Atlético Nacional Team Page

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