São Paulo vs LDU Quito Prediction, Betting Tips, Lineups & Odds | 25 Sep 2025

Copa Libertadores Betting Preview: São Paulo vs LDU Quito

Brazilian Série A club São Paulo host Ecuadorian LigaPro team LDU Quito in the second leg of this Copa Libertadores quarter-final tie, with kick-off set for 18:00 on Thursday 25 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and confirmed lineups.

Our research tells us that odds of -143 about Under 2.5 Goals looks like a solid wager for the São Paulo v LDU Quito contest. This Total Goals market bet has a strong chance of landing a return.

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São Paulo were defeated in their last game. Away from home, they suffered a 1-0 Série A loss against Santos. Hernan Crespo's men boasted 56% possession and had one shot on target.

LDU Quito were defeated in their previous game, losing 4-2 at home to Universidad Catolica in the LigaPro. Lautaro Pastran and Kevin Minda found the net for Los Albos at Estadio Rodrigo Paz Delgado.

Head-to-Head Statistics

LDU claimed a 2-0 home victory against São Paulo in the first leg. The visitors dominated possession with 59%, but it was the hosts who proved more clinical, edging the shots on target 5-4. Bryan Ramírez and Michael Estrada both found the net to give LDU a strong lead heading into the return leg.

LDU have landed victory in two of the previous 3 H2H games, with São Paulo winning once.

Copa Libertadores		G	W	D	L	GF	GA	GD	GD	P
1	LDU Quito	6	3	2	1	8	4	4	8:4	11
1	São Paulo	6	4	2	0	10	4	6	10:4	14

View Full Table

Confirmed Lineups

São Paulo confirmed lineup (4-4-2): Rafael (GK), Sabino, Robert Arboleda, Alan Franco, Emiliano Ariel Rigoni, Damian Bobadilla, Pablo Maia, Enzo Hernan Diaz, Rodriguinho, Luciano Neves, Ferreira.

LDU Quito confirmed lineup (3-5-2): Gonzalo Valle (GK), Gian Allala, Ricardo Ade, Leonel Quinonez, Jose Quinteros, Gabriel Villamil, Carlos Gruezo, Fernando Cornejo, Bryan Ramirez, Lisandro Alzugaray, Jeison Medina.

São Paulo vs LDU Quito Prediction & Betting Tips

From our main match prediction to correct score advice, must-watch player props and a custom bet builder — this São Paulo vs LDU Quito betting preview covers it all.

Match Prediction

The two teams might not deliver too many goals and that leads us to bet Under 2.5. This Copa Libertadores selection could be the way forward and that’s especially considering you can get odds of -143.

It's essential to know the players who are missing for the next clash along with the form for each of the two sides. If you’re looking for the best Copa Libertadores stats, we will showcase them and they provide the foundation for our football picks.

Key São Paulo vs LDU Quito Copa Libertadores & league stats:

• The 2.5 line hasn’t been covered in the last 6 São Paulo games.
• The 2.5 line hasn’t been covered in 8 of the last 10 São Paulo games.
• The 2.5 line hasn’t been covered in 12 of the last 20 São Paulo games.
• The 2.5 line hasn’t been covered in the last 5 LDU games on the road.
• The 2.5 line hasn’t been covered in 8 of the last 10 LDU games.
• The 2.5 line hasn’t been covered in 13 of the last 20 LDU games on the road.

The best football bookies are estimating that there is a 58.8% likelihood of this pick landing a return. However, our experts have this number between 65-70% based on their in-depth research. It’s the reason why we are recommending this bet.

For those in pursuit of a larger price, there’s an opportunity to have a wager on Under 1.5 Goals, with bettors requiring no more than one goal to be scored in order for the bet to land.

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Our Match Prediction

Under 2.5 Goals @ -143 Bet Now

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Correct Score Prediction

São Paulo 2 - 0 LDU

São Paulo are available to back at +425 to secure a 2-0 victory. This is a risky but potentially more rewarding bet, with this correct score option providing appeal.

Player Prop Picks

Top Pick: Luciano da Rocha Over 1.5 Shots On Target -115

Luciano da Rocha (São Paulo) can be backed at -115 to cover the shots on goal total. Shots on Target bettors should definitely consider him at the available odds and we’ll have a play.

Latest Luciano da Rocha Player Prop Odds

Goalscorer

Anytime

+125

First

+310

Shots On Target

Over 1.5

-147

Under 1.5

-116

Shots

Over 4.5

+104

Under 4.5

-

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Gonzalo Tapia to Score +210

Gonzalo Tapia (São Paulo) has managed two goals in his past four games on home soil. The odds that he will be an Anytime Goalscorer look attractive considering the numbers and we’ll plump for him to find the net at odds of +210.

Latest Gonzalo Tapia Player Prop Odds

Goalscorer

Anytime

+210

First

+420

Shots On Target

Over 1.5

+145

Under 1.5

-238

Shots

Over 3.5

-125

Under 3.5

-

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São Paulo vs LDU Quito Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

With an estimated 72% chance of winning, the bookies are taking few chances with their -263 betting odds about São Paulo triumphing in this Copa Libertadores clash. LDU Quito are the underdogs at +900 which implies a low percentage prospect of winning.

An Asian Handicap -1.25 bet on São Paulo gives you a full payout at -110 if they beat LDU by two or more goals. If they win by one, you get half your stake returned but will lose the other half.

If you’re anticipating that two goals or less will be netted throughout the contest, then Under 2.5 Goals is a definite runner. If you believe this suggests that there will be a one-sided or low-scoring affair, then BTTS No could be a great pick at -222.

For those wanting hundreds of football markets, it’s great that the top betting sites are on hand to offer this service. When it comes to every Copa Libertadores game, go for the pick which stands out the most.

Full-Time Result

1

-263

X

+335

2

+900

Half-Time Result

1

-109

X

+132

2

+750

Double Chance

1X

-1667

12

-455

X2

+188

Draw No Bet

1

-1111

2

+510

Asian Handicap

1 Hcp -1.25

-110

2 Hcp +1.25

-112

Total Goals

Under 2.5

-143

Over 2.5

+115

Both Teams to Score

Yes

+155

No

-222

Favourite Luciano da Rocha is +310 to be the First Goalscorer, while similar odds apply when it comes to him scoring the last goal.

Luciano da Rocha (São Paulo)

First

+125

Anytime

+310

Aldemir Ferreira (São Paulo)

First

+210

Anytime

+460

Gonzalo Tapia (São Paulo)

First

+210

Anytime

+420

André Oliveira Silva (São Paulo)

First

+220

Anytime

+420

Juan Dinenno (São Paulo)

First

+235

Anytime

+450

Emiliano Rigoni (São Paulo)

First

+280

Anytime

+650

Lucas Moura (São Paulo)

First

+310

Anytime

+650

Oscar (São Paulo)

First

+310

Anytime

+650

Rodrigo Almeida Mendonca "Rodriguinho" (São Paulo)

First

+440

Anytime

+1100

Damián Bobadilla (São Paulo)

First

+440

Anytime

+1100

Robert Arboleda (São Paulo)

First

+575

Anytime

+1500

Rafael Tolói (São Paulo)

First

+575

Anytime

+1200

Luiz Gustavo (São Paulo)

First

+650

Anytime

+1400

Michael Estrada (LDU)

First

+650

Anytime

+1500

Pablo Maia (São Paulo)

First

+750

Anytime

+1800

Marcos Antônio Silva Santos (São Paulo)

First

+800

Anytime

+1600

Cédric Soares (São Paulo)

First

+800

Anytime

+1700

Alisson Castro (São Paulo)

First

+850

Anytime

+1800

José Sabino Chagas Monteiro (São Paulo)

First

+950

Anytime

+2200

Lautaro Pastrán (LDU)

First

+1100

Anytime

+2200

Juan Dinenno (São Paulo)

Over 0.5

-250

Under 0.5

+155

Emiliano Rigoni (São Paulo)

Over 0.5

-172

Under 0.5

-100

Lucas Moura (São Paulo)

Over 0.5

-164

Under 0.5

+102

Oscar (São Paulo)

Over 0.5

-159

Under 0.5

+102

Luciano da Rocha (São Paulo)

Over 1.5

-147

Under 1.5

-116

Rodrigo Almeida Mendonca "Rodriguinho" (São Paulo)

Over 0.5

-104

Under 0.5

-164

Damián Bobadilla (São Paulo)

Over 0.5

-100

Under 0.5

-172

André Oliveira Silva (São Paulo)

Over 1.5

+140

Under 1.5

-217

Michael Estrada (LDU)

Over 0.5

+143

Under 0.5

-250

Gonzalo Tapia (São Paulo)

Over 1.5

+145

Under 1.5

-238

Aldemir Ferreira (São Paulo)

Over 1.5

+155

Under 1.5

-286

Rafael Tolói (São Paulo)

Over 0.5

+155

Under 0.5

-250

Luiz Gustavo (São Paulo)

Over 0.5

+165

Under 0.5

-270

Robert Arboleda (São Paulo)

Over 0.5

+190

Under 0.5

-370

Pablo Maia (São Paulo)

Over 0.5

+220

Under 0.5

-455

Marcos Antônio Silva Santos (São Paulo)

Over 0.5

+220

Under 0.5

-400

Cédric Soares (São Paulo)

Over 0.5

+225

Under 0.5

-400

Alisson Castro (São Paulo)

Over 0.5

+240

Under 0.5

-435

Lautaro Pastrán (LDU)

Over 0.5

+250

Under 0.5

-476

José Sabino Chagas Monteiro (São Paulo)

Over 0.5

+310

Under 0.5

-833

Luciano da Rocha (São Paulo)

Over 4.5

+104

Under 4.5

-

Gonzalo Tapia (São Paulo)

Over 3.5

-125

Under 3.5

-

André Oliveira Silva (São Paulo)

Over 3.5

-152

Under 3.5

-

Juan Dinenno (São Paulo)

Over 3.5

-108

Under 3.5

-

Aldemir Ferreira (São Paulo)

Over 3.5

-133

Under 3.5

-

Rodrigo Almeida Mendonca "Rodriguinho" (São Paulo)

Over 2.5

+123

Under 2.5

-

Damián Bobadilla (São Paulo)

Over 2.5

+123

Under 2.5

-

Oscar (São Paulo)

Over 2.5

-111

Under 2.5

-

Lucas Moura (São Paulo)

Over 2.5

-125

Under 2.5

-

Emiliano Rigoni (São Paulo)

Over 2.5

-125

Under 2.5

-

Rafael Tolói (São Paulo)

Over 1.5

+135

Under 1.5

-

Luiz Gustavo (São Paulo)

Over 1.5

+133

Under 1.5

-

Michael Estrada (LDU)

Over 1.5

+108

Under 1.5

-

Pablo Maia (São Paulo)

Over 1.5

+155

Under 1.5

-

Robert Arboleda (São Paulo)

Over 0.5

-244

Under 0.5

-

Cédric Soares (São Paulo)

Over 0.5

-128

Under 0.5

-

Alisson Castro (São Paulo)

Over 0.5

-192

Under 0.5

-

José Sabino Chagas Monteiro (São Paulo)

Over 0.5

-125

Under 0.5

-

Lautaro Pastrán (LDU)

Over 0.5

-154

Under 0.5

-

Latest Copa Libertadores and domestic league stats. Full Time Result, Goals, Corners and Possession.

São Paulo Stats

LDU Quito Stats

Full-Time Result

• 7 wins, 2 defeats and 1 draw in the previous 10 matches
• 7 wins, 2 defeats and 1 draw in the previous 10 home matches

Full-Time Result

• 4 wins, 3 defeats and 3 draws in the previous 10 matches
• 5 wins, 4 defeats and 1 draw in the previous 10 away matches

Goals

• An average of 1.50 goals scored and 0.60 conceded in the previous 10 matches
• An average of 1.50 goals scored and 0.80 conceded in the previous 10 home matches
• An average of 2.10 goals per game in the previous 10 matches
• An average of 2.30 goals per game in the previous 10 home matches
• BTTS Yes in 3 of the previous 10 matches
• BTTS Yes in 4 of the previous 10 home matches
• Over 2.5 Goals in 3 of the previous 10 matches
• Over 2.5 Goals in 4 of the previous 10 home matches

Goals

• An average of 1.20 goals scored and 1.10 conceded in the previous 10 matches
• An average of 1.20 goals scored and 0.90 conceded in the previous 10 away matches
• An average of 2.30 goals per game in the previous 10 matches
• An average of 2.10 goals per game in the previous 10 away matches
• BTTS Yes in 5 of the previous 10 matches
• BTTS Yes in 4 of the previous 10 away matches
• Over 2.5 Goals in 3 of the previous 10 matches
• Over 2.5 Goals in 4 of the previous 10 away matches

São Paulo vs LDU Quito Lineups & Team News

The São Paulo vs LDU team news could change everything — review it before betting. We’ll share both predicted and confirmed lineups for the Copa Libertadores along with the latest injury news.

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