São Paulo vs LDU Quito Prediction, Betting Tips, Lineups & Odds | 25 Sep 2025
Copa Libertadores Betting Preview: São Paulo vs LDU Quito
Brazilian Série A club São Paulo host Ecuadorian LigaPro team LDU Quito in the second leg of this Copa Libertadores quarter-final tie, with kick-off set for 18:00 on Thursday 25 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and confirmed lineups.
Go For Under 2.5 Goals With Confidence
Our research tells us that odds of -143 about Under 2.5 Goals looks like a solid wager for the São Paulo v LDU Quito contest. This Total Goals market bet has a strong chance of landing a return.
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LDU Struck Twice to Defeat São Paulo in First Leg
São Paulo were defeated in their last game. Away from home, they suffered a 1-0 Série A loss against Santos. Hernan Crespo's men boasted 56% possession and had one shot on target.
LDU Quito were defeated in their previous game, losing 4-2 at home to Universidad Catolica in the LigaPro. Lautaro Pastran and Kevin Minda found the net for Los Albos at Estadio Rodrigo Paz Delgado.
Head-to-Head Statistics
LDU claimed a 2-0 home victory against São Paulo in the first leg. The visitors dominated possession with 59%, but it was the hosts who proved more clinical, edging the shots on target 5-4. Bryan Ramírez and Michael Estrada both found the net to give LDU a strong lead heading into the return leg.
LDU have landed victory in two of the previous 3 H2H games, with São Paulo winning once.
| Copa Libertadores | G | W | D | L | GF | GA | GD | GD | P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  LDU Quito |
6 | 3 | 2 | 1 | 8 | 4 | 4 | 8:4 | 11 |
| 1 |  São Paulo |
6 | 4 | 2 | 0 | 10 | 4 | 6 | 10:4 | 14 |
São Paulo vs LDU Quito Prediction & Betting Tips
From our main match prediction to correct score advice, must-watch player props and a custom bet builder — this São Paulo vs LDU Quito betting preview covers it all.
Match Prediction
The two teams might not deliver too many goals and that leads us to bet Under 2.5. This Copa Libertadores selection could be the way forward and that’s especially considering you can get odds of -143.
It's essential to know the players who are missing for the next clash along with the form for each of the two sides. If you’re looking for the best Copa Libertadores stats, we will showcase them and they provide the foundation for our football picks.
Key São Paulo vs LDU Quito Copa Libertadores & league stats:
Under 2.5 Probability
The best football bookies are estimating that there is a 58.8% likelihood of this pick landing a return. However, our experts have this number between 65-70% based on their in-depth research. It’s the reason why we are recommending this bet.
For those in pursuit of a larger price, there’s an opportunity to have a wager on Under 1.5 Goals, with bettors requiring no more than one goal to be scored in order for the bet to land.
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Correct Score Prediction
2
-
0
LDU
São Paulo are available to back at +430 to secure a 2-0 victory. This is a risky but potentially more rewarding bet, with this correct score option providing appeal.
Player Prop Picks
Luciano da Rocha (São Paulo) can be backed at -115 to cover the shots on goal total. Shots on Target bettors should definitely consider him at the available odds and we’ll have a play.
T&C apply. Gamble responsibly 18+
Gonzalo Tapia (São Paulo) has managed two goals in his past four games on home soil. The odds that he will be an Anytime Goalscorer look attractive considering the numbers and we’ll plump for him to find the net at odds of +210.
T&C apply. Gamble responsibly 18+
Bet Builder Tips
Our bet builder picks are two or less goals, São Paulo to cover the -1.25 Asian Handicap accompanied by Luciano da Rocha (São Paulo) to cover the 1.5 Shots on Target line.
Should you want to back different outcomes for the same football game, then a bet builder will suit your needs. You can predict different outcomes and see their odds combined before going ahead and placing this tailored bet.
São Paulo vs LDU Quito Odds
The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.
São Paulo Big Favourites With the Bookies
With an estimated 71% chance of winning, the bookies are taking few chances with their -250 betting odds about São Paulo triumphing in this Copa Libertadores clash. LDU Quito are the underdogs at +800 which implies a low percentage prospect of winning.
An Asian Handicap -1.25 bet on São Paulo gives you a full payout at -104 if they beat LDU by two or more goals. If they win by one, you get half your stake returned but will lose the other half.
If you’re anticipating that two goals or less will be netted throughout the contest, then Under 2.5 Goals is a definite runner. If you believe this suggests that there will be a one-sided or low-scoring affair, then BTTS No could be a great pick at -213.
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Luciano da Rocha is the First Goalscorer Favourite
Favourite Luciano da Rocha is +310 to be the First Goalscorer, while similar odds apply when it comes to him scoring the last goal.
Latest Copa Libertadores and domestic league stats. Full Time Result, Goals, Corners and Possession.
São Paulo Stats
LDU Quito Stats
- 7 wins, 2 defeats and 1 draw in the previous 10 matches
- 7 wins, 2 defeats and 1 draw in the previous 10 home matches
- 4 wins, 3 defeats and 3 draws in the previous 10 matches
- 5 wins, 4 defeats and 1 draw in the previous 10 away matches
- An average of 1.50 goals scored and 0.60 conceded in the previous 10 matches
- An average of 1.50 goals scored and 0.80 conceded in the previous 10 home matches
- An average of 2.10 goals per game in the previous 10 matches
- An average of 2.30 goals per game in the previous 10 home matches
- BTTS Yes in 3 of the previous 10 matches
- BTTS Yes in 4 of the previous 10 home matches
- Over 2.5 Goals in 3 of the previous 10 matches
- Over 2.5 Goals in 4 of the previous 10 home matches
- An average of 1.20 goals scored and 1.10 conceded in the previous 10 matches
- An average of 1.20 goals scored and 0.90 conceded in the previous 10 away matches
- An average of 2.30 goals per game in the previous 10 matches
- An average of 2.10 goals per game in the previous 10 away matches
- BTTS Yes in 5 of the previous 10 matches
- BTTS Yes in 4 of the previous 10 away matches
- Over 2.5 Goals in 3 of the previous 10 matches
- Over 2.5 Goals in 4 of the previous 10 away matches
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São Paulo vs LDU Quito Lineups & Team News
The São Paulo vs LDU team news could change everything — review it before betting. We’ll share both predicted and confirmed lineups for the Copa Libertadores along with the latest injury news.
Previous São Paulo Lineups
Previous LDU Quito Lineups
São Paulo Squad
LDU Quito Squad| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Estudiantes | 6 | 4 | 0 | 2 | 11:5 | 12 |
| 2 | Botafogo | 6 | 4 | 0 | 2 | 8:5 | 12 |
| 3 | U. de Chile | 6 | 3 | 1 | 2 | 8:6 | 10 |
| 4 | Carabobo FC | 6 | 0 | 1 | 5 | 2:13 | 1 |
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | River Plate | 6 | 3 | 3 | 0 | 13:7 | 12 |
| 2 | Universitario | 6 | 2 | 2 | 2 | 4:4 | 8 |
| 3 | IDV | 6 | 2 | 2 | 2 | 8:11 | 8 |
| 4 | Barcelona | 6 | 1 | 1 | 4 | 4:7 | 4 |
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | LDU Quito | 6 | 3 | 2 | 1 | 8:4 | 11 |
| 2 | Flamengo | 6 | 3 | 2 | 1 | 6:3 | 11 |
| 3 | Central Córdoba | 6 | 3 | 2 | 1 | 7:7 | 11 |
| 4 | Deportivo Táchira | 6 | 0 | 0 | 6 | 4:11 | 0 |
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | São Paulo | 6 | 4 | 2 | 0 | 10:4 | 14 |
| 2 | Libertad | 6 | 2 | 3 | 1 | 6:5 | 9 |
| 3 | Alianza Lima | 6 | 1 | 2 | 3 | 7:11 | 5 |
| 4 | Talleres | 6 | 1 | 1 | 4 | 5:8 | 4 |
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Racing Club | 6 | 4 | 1 | 1 | 14:3 | 13 |
| 2 | Fortaleza | 6 | 2 | 2 | 2 | 8:5 | 8 |
| 3 | Bucaramanga | 6 | 1 | 3 | 2 | 6:10 | 6 |
| 4 | Colo-Colo | 6 | 1 | 2 | 3 | 5:15 | 5 |
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Internacional | 6 | 3 | 2 | 1 | 12:8 | 11 |
| 2 | Atlético Nacional | 6 | 3 | 0 | 3 | 7:6 | 9 |
| 3 | Bahia | 6 | 2 | 1 | 3 | 5:7 | 7 |
| 4 | Nacional | 6 | 2 | 1 | 3 | 7:10 | 7 |
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Palmeiras | 6 | 6 | 0 | 0 | 17:4 | 18 |
| 2 | Cerro Porteño | 6 | 2 | 1 | 3 | 7:11 | 7 |
| 3 | Bolivar | 6 | 2 | 0 | 4 | 12:11 | 6 |
| 4 | Sporting Cristal | 6 | 1 | 1 | 4 | 6:16 | 4 |
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Vélez Sarsfield | 6 | 3 | 2 | 1 | 11:4 | 11 |
| 2 | Peñarol | 6 | 3 | 2 | 1 | 9:4 | 11 |
| 3 | San Antonio Bulo Bulo | 6 | 2 | 0 | 4 | 5:15 | 6 |
| 4 | Olimpia | 6 | 1 | 2 | 3 | 9:11 | 5 |
Palmeiras
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Ekstraklasa
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La Liga
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Alavés
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