Sevilla vs Villarreal Prediction, Betting Tips, Lineups & Odds | 23 Sep 2025

La Liga Betting Preview: Sevilla vs Villarreal

Sevilla host Villarreal in this Spanish La Liga fixture at Estadio Ramón Sánchez Pizjuán, with kick-off set for 15:30 on Tuesday 23 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

Back Sevilla to Make Life Difficult for Villarreal

We’ll split our stake by backing Sevilla +0.25 at odds of -122 for this Asian Handicap wager. It means we have a return if they draw but a nice payout should the home team claim a victory against Villarreal.

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4-2 Win for Villarreal in Pair’s Last Meeting

Sevilla won their last game. It was on the road where Deportivo Alavés were beaten 2-1 at Estadio Mendizorroza. The Andalusia club recorded 52% possession and managed three shots on target, with Ruben Vargas and Alexis Sanchez each scoring one goal.

Villarreal won their previous game, beating Osasuna at home. It was a 2-1 win at Estadio de la Ceramica. Marcelino Garcia's side enjoyed 66% possession and managed eight shots on goal, while Georges Mikautadze and Pape Gueye were on the scoresheet.

Head-to-Head Statistics

Villarreal have beaten Sevilla on three consecutive occasions. In the last encounter, home team Villarreal claimed a 4-2 win at Estadio de la Ceramica. The previous 10 H2H meetings have involved four Villarreal wins, three Sevilla victories and three draws.

La Liga		G	W	D	L	GF	GA	GD	GD	P
3	Villarreal	11	7	2	2	22	10	12	22:10	23
13	Sevilla	11	4	1	6	17	19	-2	17:19	13

View Full Table

3 wins, 5 losses and 2 draws, averaging 1.6 goals from 4.5 shots on goal and 12.8 attempts. Sevilla have had 51.1% possession, 417.6 passes and 3.9 corners per game. On average, their opponents have scored 1.9 goals from 4.4 shots on goal and 11.4 attempts, while being awarded 4.7 corners.

Isaac Romero is the top goalscorer with 3, Kike Salas has 2, with Alexis Sanchez and two other players on 1. Leading assistor is Ruben Vargas with 3, while goalkeeper Oerjan Haaskjold Nyland has 2 clean sheets.

Villarreal have won 8, lost 1 and drawn 1, with an average of 2.5 goals from 5.8 shots on goal and 14.8 attempts. El Submarino Amarillo have averaged 47.2% possession, 440.4 passes, 4.7 corners taken and 4.6 corners against, while conceding 1.0 goals from 4.0 shots on goal and 11.5 attempts.

Ayoze Perez has top scored with 5, while Pape Gueye, Nicolas Pepe and Tajon Buchanan are next on 4. Nicolas Pepe has had 4 assists, with Luiz Junior notching 4 clean sheets in the previous 10 games.

Confirmed Lineups

Sevilla confirmed lineup (4-4-2): Odysseas Vlachodimos (GK), Cesar Azpilicueta, Andres Castrin, Kike Salas, Juanlu Sanchez, Nemanja Gudelj, Djibril Sow, Gabriel Suazo, Chidera Ejuke, Adnan Januzaj, Akor Adams.

Villarreal confirmed lineup (4-3-3): Arnau Tenas (GK), Santiago Mourino, Rafa Marin, Renato Veiga, Sergi Cardona, Daniel Parejo, Pape Gueye, Santi Comesana, Tajon Buchanan, Tani Oluwaseyi, Alberto Moleiro.

Sevilla vs Villarreal Prediction & Betting Tips

Gear up for Sevilla vs Villarreal with our comprehensive betting guide, featuring an expert match prediction, scoreline advice, corners market value, top player props and a hand-picked bet builder.

Match Prediction

Back Sevilla with a +0.25 Asian Handicap at -122 for this La Liga encounter. We’re sweet on their chances of outperforming the match winner odds and this bet is a value proposition.

Our panel of football writers survey the latest injuries and suspensions. When combined with the form guide, this helps us secure the best odds. Our stats-led approach backed up by key La Liga data is helpful.

Key Sevilla vs Villarreal league stats:

• The +0.25 line has been covered by Sevilla in 3 consecutive games.
• The +0.25 line has been covered by Sevilla in 13 of their last 20 games at home.
• The -0.25 line hasn’t been covered by Villarreal in 3 of their last 5 games on the road.
• The -0.25 line hasn’t been covered by Villarreal in 2 consecutive games on the road.
• The +0.25 line has been covered by Sevilla in 6 of their last 10 games against Villarreal.

Sevilla +0.25 Probability

The best football bookies are estimating that there is a 54.9% likelihood of this pick landing a return. In our opinion, there’s actually a probability of success closer to 60%. It’s why we think it’s worth placing this wager.

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Our Match Prediction

Sevilla Asian Hcp +0.25 @ -122 Bet Now

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Correct Score Prediction

Sevilla 2 - 1 Villarreal

Sevilla are available at +900 to secure a 2-1 victory. Many bettors enjoy a correct score wager and there are some nice potential returns to be had.

Player Prop Picks

Top Pick: Nicolas Pepe Under 0.5 Shots On Target -105

Nicolas Pepe (Villarreal) hasn’t had a shot on goal in back-to-back La Liga games. There is juice when it comes to going under the Shots on Target line and this is priced at -105.

Latest Nicolas Pepe Player Prop Odds

Goalscorer

Anytime

+280

First

+600

Shots On Target

Over 0.5

-139

Under 0.5

-112

Shots

Over 2.5

-102

Under 2.5

-

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Isaac Romero to Score +350

Isaac Romero (Sevilla) has scored two goals in his past four La Liga matches on home soil. We think this is the pick of the player props, with a generous +350 available when it comes to backing him to score at any time.

Latest Isaac Romero Player Prop Odds

Goalscorer

Anytime

+350

First

+750

Shots On Target

Over 0.5

-102

Under 0.5

-154

Shots

Over 1.5

-175

Under 1.5

-

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Corners Prediction

Sevilla Under 4.5 Corners -106

Sevilla have failed to cover the 4.5 corners line in three straight games, while Villarreal have let the opposition have an average of 2.20 corners in their last 5 matches. There’s a price of -106 for this Team Corners bet and we think the Sevilla line is too big.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Sevilla

Total

8.60 3.90 4.70

Home

8.80 4.30 4.50

Away

8.90 3.70 5.20

Villarreal

Total

9.30 4.70 4.60

Home

10.80 6.80 4.00

Away

8.80 3.90 4.90

Latest Corner Odds

Total Corners

Over 9.5

-110

Under 9.5

-128

Sevilla Corners

Over 4.5

-110

Under 4.5

-125

Villarreal Corners

Over 4.5

-100

Under 4.5

-138

Most Corners

1

+114

X

+600

2

-100

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Sevilla vs Villarreal Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Close Game On the Cards According to Latest Odds

Villarreal are the shortest price to win this La Liga clash according to the bookies, with the favourites given a 45% probability due to their +120 betting odds. If you want to wager on the underdog, Sevilla have been priced up at +225.

Should you want to back Villarreal to win but want money back if the game ends level, then there is -175 available on the Draw No Bet market. Opponents Sevilla have been chalked up at +128.

The Total Goals market looks like a close call, with Over and Under 2.5 Goals available at similar odds. BTTS betting is always a warm order and you can bet Yes at -141 on the Both Teams to Score market.

The recommended betting sites push the boat out to ensure that football bettors can select from hundreds of markets. You can access them for every La Liga game before making a decision.

Full-Time Result

1

+225

X

+230

2

+120

Half-Time Result

1

+275

X

+116

2

+180

Double Chance

1X

-159

12

-313

X2

-313

Draw No Bet

1

+128

2

-175

Asian Handicap

1 Hcp +0.25

-111

2 Hcp -0.25

-111

Total Goals

Under 2.5

-118

Over 2.5

-109

Both Teams to Score

Yes

-141

No

+104

Georges Mikautadze Favourite to Score the First Goal

Georges Mikautadze can be backed to find the net anytime at +185. There is the chance to back the market leader to score the first goal at +400.

Georges Mikautadze (Villarreal)

First

+185

Anytime

+400

Ayoze Pérez (Villarreal)

First

+250

Anytime

+575

Tani Oluwaseyi (Villarreal)

First

+260

Anytime

+600

Nicolas Pepe (Villarreal)

First

+280

Anytime

+600

Akor Jerome Adams (Sevilla)

First

+280

Anytime

+650

Isaac Romero (Sevilla)

First

+350

Anytime

+750

Alfonso González (Sevilla)

First

+350

Anytime

+850

Manor Solomon (Villarreal)

First

+380

Anytime

+800

Alexis Sánchez (Sevilla)

First

+380

Anytime

+900

Tajon Buchanan (Villarreal)

First

+390

Anytime

+950

Rubén Vargas (Sevilla)

First

+430

Anytime

+1000

Gerard Fernández "Peque" (Sevilla)

First

+430

Anytime

+950

Alberto Moleiro (Villarreal)

First

+440

Anytime

+1000

Adnan Januzaj (Sevilla)

First

+480

Anytime

+1200

Chidera Ejuke (Sevilla)

First

+500

Anytime

+1150

Pape Gueye (Villarreal)

First

+575

Anytime

+1500

Juanlu Sánchez (Sevilla)

First

+650

Anytime

+1600

Dani Parejo (Villarreal)

First

+650

Anytime

+1700

Nemanja Gudelj (Sevilla)

First

+700

Anytime

+1800

Alfonso Pedraza (Villarreal)

First

+750

Anytime

+1600

Renato Veiga (Villarreal)

First

+900

Anytime

+2200

Santi Comesaña (Villarreal)

First

+950

Anytime

+2200

Georges Mikautadze (Villarreal)

Over 0.5

-222

Under 0.5

+135

Ayoze Pérez (Villarreal)

Over 0.5

-147

Under 0.5

-108

Akor Jerome Adams (Sevilla)

Over 0.5

-147

Under 0.5

-116

Tani Oluwaseyi (Villarreal)

Over 0.5

-143

Under 0.5

-116

Nicolas Pepe (Villarreal)

Over 0.5

-139

Under 0.5

-112

Alfonso González (Sevilla)

Over 0.5

-120

Under 0.5

-130

Isaac Romero (Sevilla)

Over 0.5

-102

Under 0.5

-154

Alexis Sánchez (Sevilla)

Over 0.5

+105

Under 0.5

-167

Manor Solomon (Villarreal)

Over 0.5

+115

Under 0.5

-182

Gerard Fernández "Peque" (Sevilla)

Over 0.5

+125

Under 0.5

-200

Rubén Vargas (Sevilla)

Over 0.5

+128

Under 0.5

-204

Tajon Buchanan (Villarreal)

Over 0.5

+133

Under 0.5

-233

Alberto Moleiro (Villarreal)

Over 0.5

+155

Under 0.5

-278

Adnan Januzaj (Sevilla)

Over 0.5

+155

Under 0.5

-278

Chidera Ejuke (Sevilla)

Over 0.5

+160

Under 0.5

-286

Pape Gueye (Villarreal)

Over 0.5

+180

Under 0.5

-333

Juanlu Sánchez (Sevilla)

Over 0.5

+225

Under 0.5

-476

Dani Parejo (Villarreal)

Over 0.5

+270

Under 0.5

-625

Alfonso Pedraza (Villarreal)

Over 0.5

+270

Under 0.5

-556

Nemanja Gudelj (Sevilla)

Over 0.5

+330

Under 0.5

-1000

Renato Veiga (Villarreal)

Over 0.5

+360

Under 0.5

-1111

Santi Comesaña (Villarreal)

Over 0.5

+390

Under 0.5

-1429

Georges Mikautadze (Villarreal)

Over 2.5

-120

Under 2.5

-

Ayoze Pérez (Villarreal)

Over 2.5

+128

Under 2.5

-

Tani Oluwaseyi (Villarreal)

Over 2.5

+112

Under 2.5

-

Nicolas Pepe (Villarreal)

Over 2.5

-102

Under 2.5

-

Akor Jerome Adams (Sevilla)

Over 2.5

-100

Under 2.5

-

Alfonso González (Sevilla)

Over 2.5

+135

Under 2.5

-

Pape Gueye (Villarreal)

Over 1.5

-189

Under 1.5

-

Chidera Ejuke (Sevilla)

Over 1.5

+115

Under 1.5

-

Adnan Januzaj (Sevilla)

Over 1.5

+115

Under 1.5

-

Alberto Moleiro (Villarreal)

Over 1.5

-135

Under 1.5

-

Rubén Vargas (Sevilla)

Over 1.5

-119

Under 1.5

-

Gerard Fernández "Peque" (Sevilla)

Over 1.5

-123

Under 1.5

-

Tajon Buchanan (Villarreal)

Over 1.5

+117

Under 1.5

-

Alexis Sánchez (Sevilla)

Over 1.5

-156

Under 1.5

-

Manor Solomon (Villarreal)

Over 1.5

-133

Under 1.5

-

Isaac Romero (Sevilla)

Over 1.5

-175

Under 1.5

-

Juanlu Sánchez (Sevilla)

Over 0.5

-222

Under 0.5

-

Dani Parejo (Villarreal)

Over 0.5

-141

Under 0.5

-

Nemanja Gudelj (Sevilla)

Over 0.5

-123

Under 0.5

-

Renato Veiga (Villarreal)

Over 0.5

+110

Under 0.5

-

Santi Comesaña (Villarreal)

Over 0.5

-114

Under 0.5

-

Sevilla Aiming to Get Back to Winning Ways at Home

Sevilla have not won at Estadio Ramón Sánchez Pizjuán in the past three matches. The Andalusia outfit have collected five losses, four draws and one victory in the past 10 home matches, scoring an average of 1.00 goals per game and conceding 1.70.

Villarreal have secured six victories, three defeats and one draw in the previous 10 away games, netting an average of 1.20 goals per match and conceding 1.20.

The most recent Estadio Ramón Sánchez Pizjuán meeting saw Villarreal claim a 2-1 win over Sevilla. The 6 past H2H games at Estadio Ramón Sánchez Pizjuán have involved three Sevilla victories, one draw and two Villarreal wins.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Sevilla Home Stats		1-4-5	2.70	1.00	1.70	5	5	7	3
Villarreal Away Stats		6-1-3	2.40	1.20	1.20	5	5	5	5

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

Sevilla vs Villarreal Lineups & Team News

Before making your bets, take a look at the Sevilla vs Villarreal team news. We’ll have the predicted and confirmed La Liga lineups for you plus all the latest on player injuries.

Sevilla Team Page Villarreal Team Page