Sevilla vs Villarreal Prediction, Betting Tips, Lineups & Odds | 23 Sep 2025

La Liga Betting Preview: Sevilla vs Villarreal

Sevilla host Villarreal in this Spanish La Liga fixture at Estadio Ramón Sánchez Pizjuán, with kick-off set for 15:30 on Tuesday 23 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

Back Sevilla to Make Life Difficult for Villarreal

We’ll split our stake by backing Sevilla +0.25 at odds of -122 for this Asian Handicap wager. It means we have a return if they draw but a nice payout should the home team claim a victory against Villarreal.

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4-2 Win for Villarreal in Pair’s Last Meeting

Sevilla won their last game. It was on the road where Deportivo Alavés were beaten 2-1 at Estadio Mendizorroza. The Andalusia club recorded 52% possession and managed three shots on target, with Ruben Vargas and Alexis Sanchez each scoring one goal.

Villarreal won their previous game, beating Osasuna at home. It was a 2-1 win at Estadio de la Ceramica. Marcelino Garcia's side enjoyed 66% possession and managed eight shots on goal, while Georges Mikautadze and Pape Gueye were on the scoresheet.

Head-to-Head Statistics

Villarreal have beaten Sevilla on three consecutive occasions. In the last encounter, home team Villarreal claimed a 4-2 win at Estadio de la Ceramica. The previous 10 H2H meetings have involved four Villarreal wins, three Sevilla victories and three draws.

La Liga		G	W	D	L	GF	GA	GD	GD	P
3	Villarreal	5	3	1	1	10	4	6	10:4	10
9	Sevilla	5	2	1	2	9	8	1	9:8	7

View Full Table

3 wins, 5 losses and 2 draws, averaging 1.6 goals from 4.5 shots on goal and 12.8 attempts. Sevilla have had 51.1% possession, 417.6 passes and 3.9 corners per game. On average, their opponents have scored 1.9 goals from 4.4 shots on goal and 11.4 attempts, while being awarded 4.7 corners.

Isaac Romero is the top goalscorer with 3, Kike Salas has 2, with Alexis Sanchez and two other players on 1. Leading assistor is Ruben Vargas with 3, while goalkeeper Oerjan Haaskjold Nyland has 2 clean sheets.

Villarreal have won 8, lost 1 and drawn 1, with an average of 2.5 goals from 5.8 shots on goal and 14.8 attempts. El Submarino Amarillo have averaged 47.2% possession, 440.4 passes, 4.7 corners taken and 4.6 corners against, while conceding 1.0 goals from 4.0 shots on goal and 11.5 attempts.

Ayoze Perez has top scored with 5, while Pape Gueye, Nicolas Pepe and Tajon Buchanan are next on 4. Nicolas Pepe has had 4 assists, with Luiz Junior notching 4 clean sheets in the previous 10 games.

Predicted & Confirmed Lineups

Sevilla predicted lineup (3-4-2-1): Odisseas Vlachodimos (GK), Cesar Azpilicueta, Tanguy Nianzou Kouassi, Marcos Teixeira Marcão, José Ángel Carmona, Lucien Agoumé, Batista Mendy, Gabriel Suazo, Ruben Vargas, Alfonso Gonzalez, Isaac Romero.

Villarreal predicted lineup (4-4-2): Luiz Júnior (GK), Pau Navarro, Santiago Mouriño, Rafa Marín, Alfonso Pedraza, Tajon Buchanan, Pape Gueye, Thomas Partey, Alberto Moleiro, Nicolas Pepe, Georges Mikautadze.

Sevilla vs Villarreal Prediction & Betting Tips

Gear up for Sevilla vs Villarreal with our comprehensive betting guide, featuring an expert match prediction, scoreline advice, corners market value, top player props and a hand-picked bet builder.

Match Prediction

Back Sevilla with a +0.25 Asian Handicap at -122 for this La Liga encounter. We’re sweet on their chances of outperforming the match winner odds and this bet is a value proposition.

Our panel of football writers survey the latest injuries and suspensions. When combined with the form guide, this helps us secure the best odds. Our stats-led approach backed up by key La Liga data is helpful.

Key Sevilla vs Villarreal league stats:

• The +0.25 line has been covered by Sevilla in 3 consecutive games.
• The +0.25 line has been covered by Sevilla in 13 of their last 20 games at home.
• The -0.25 line hasn’t been covered by Villarreal in 3 of their last 5 games on the road.
• The -0.25 line hasn’t been covered by Villarreal in 2 consecutive games on the road.
• The +0.25 line has been covered by Sevilla in 6 of their last 10 games against Villarreal.

Sevilla +0.25 Probability

The best football bookies are estimating that there is a 54.9% likelihood of this pick landing a return. In our opinion, there’s actually a probability of success closer to 60%. It’s why we think it’s worth placing this wager.

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Our Match Prediction

Sevilla Asian Hcp +0.25 @ -122 Watch Live Bet Now

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Correct Score Prediction

Sevilla 2 - 1 Villarreal

Sevilla are available at +900 to secure a 2-1 victory. Many bettors enjoy a correct score wager and there are some nice potential returns to be had.

Player Prop Picks

Top Pick: Nicolas Pepe Under 0.5 Shots On Target -105

Nicolas Pepe (Villarreal) hasn’t had a shot on goal in back-to-back La Liga games. There is juice when it comes to going under the Shots on Target line and this is priced at -105.

Latest Nicolas Pepe Player Prop Odds

Goalscorer

Anytime

+260

First

+600

Shots On Target

Over 0.5

-149

Under 0.5

-105

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Isaac Romero to Score +350

Isaac Romero (Sevilla) has scored two goals in his past four La Liga matches on home soil. We think this is the pick of the player props, with a generous +350 available when it comes to backing him to score at any time.

Latest Isaac Romero Player Prop Odds

Goalscorer

Anytime

+350

First

+800

Shots On Target

Over 0.5

+102

Under 0.5

-159

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Corners Prediction

Sevilla Under 4.5 Corners -106

Sevilla have failed to cover the 4.5 corners line in three straight games, while Villarreal have let the opposition have an average of 2.20 corners in their last 5 matches. There’s a price of -106 for this Team Corners bet and we think the Sevilla line is too big.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Sevilla

Total

8.60 3.90 4.70

Home

8.80 4.30 4.50

Away

8.90 3.70 5.20

Villarreal

Total

9.30 4.70 4.60

Home

10.80 6.80 4.00

Away

8.80 3.90 4.90

Latest Corner Odds

Total Corners

Over 9.5

-120

Under 9.5

-118

Sevilla Corners

Over 4.5

-110

Under 4.5

-125

Villarreal Corners

Over 4.5

-100

Under 4.5

-138

Most Corners

1

-100

X

+650

2

+112

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Sevilla vs Villarreal Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Close Game On the Cards According to Latest Odds

The bookies have chalked up the draw at +230 on the 1x2 betting, with Villarreal available to bet at odds of +132. Sevilla are +205 to claim victory in this La Liga encounter.

Should you want to back Villarreal to win but want money back if the game ends level, then there is -154 available on the Draw No Bet market. Opponents Sevilla have been chalked up at +114.

The Total Goals market looks like a close call, with Over and Under 2.5 Goals available at similar odds. BTTS betting is always a warm order and you can bet Yes at -154 on the Both Teams to Score market.

The recommended betting sites push the boat out to ensure that football bettors can select from hundreds of markets. You can access them for every La Liga game before making a decision.

Full-Time Result

1

+205

X

+230

2

+132

Half-Time Result

1

+255

X

+120

2

+185

Double Chance

1X

-175

12

-313

X2

-278

Draw No Bet

1

+114

2

-154

Asian Handicap

1 Hcp +0.25

-122

2 Hcp -0.25

-100

Total Goals

Under 2.5

-108

Over 2.5

-119

Both Teams to Score

Yes

-154

No

+112

Georges Mikautadze Favourite to Score the First Goal

Georges Mikautadze can be backed to find the net anytime at +175. There is the chance to back the market leader to score the first goal at +380.

Georges Mikautadze (Villarreal)

First

+175

Anytime

+380

Ayoze Pérez (Villarreal)

First

+250

Anytime

+550

Nicolas Pepe (Villarreal)

First

+260

Anytime

+600

Tani Oluwaseyi (Villarreal)

First

+290

Anytime

+650

Akor Jerome Adams (Sevilla)

First

+290

Anytime

+700

Alfonso González (Sevilla)

First

+330

Anytime

+800

Isaac Romero (Sevilla)

First

+350

Anytime

+800

Alexis Sánchez (Sevilla)

First

+350

Anytime

+850

Manor Solomon (Villarreal)

First

+370

Anytime

+800

Gerard Fernández "Peque" (Sevilla)

First

+400

Anytime

+950

Rubén Vargas (Sevilla)

First

+420

Anytime

+1050

Tajon Buchanan (Villarreal)

First

+430

Anytime

+1000

Alberto Moleiro (Villarreal)

First

+480

Anytime

+1000

Adnan Januzaj (Sevilla)

First

+480

Anytime

+1200

Chidera Ejuke (Sevilla)

First

+500

Anytime

+1150

Pape Gueye (Villarreal)

First

+650

Anytime

+1500

Juanlu Sánchez (Sevilla)

First

+650

Anytime

+1600

Alfonso Pedraza (Villarreal)

First

+700

Anytime

+1600

Dani Parejo (Villarreal)

First

+700

Anytime

+1700

Santi Comesaña (Villarreal)

First

+1050

Anytime

+2200

Renato Veiga (Villarreal)

First

+1050

Anytime

+2200

Georges Mikautadze (Villarreal)

Over 0.5

-233

Under 0.5

+140

Nicolas Pepe (Villarreal)

Over 0.5

-149

Under 0.5

-105

Ayoze Pérez (Villarreal)

Over 0.5

-147

Under 0.5

-109

Tani Oluwaseyi (Villarreal)

Over 0.5

-130

Under 0.5

-123

Akor Jerome Adams (Sevilla)

Over 0.5

-130

Under 0.5

-119

Alfonso González (Sevilla)

Over 0.5

-111

Under 0.5

-139

Isaac Romero (Sevilla)

Over 0.5

+102

Under 0.5

-159

Alexis Sánchez (Sevilla)

Over 0.5

+112

Under 0.5

-179

Manor Solomon (Villarreal)

Over 0.5

+118

Under 0.5

-185

Rubén Vargas (Sevilla)

Over 0.5

+135

Under 0.5

-227

Gerard Fernández "Peque" (Sevilla)

Over 0.5

+135

Under 0.5

-233

Tajon Buchanan (Villarreal)

Over 0.5

+145

Under 0.5

-238

Alberto Moleiro (Villarreal)

Over 0.5

+163

Under 0.5

-263

Chidera Ejuke (Sevilla)

Over 0.5

+165

Under 0.5

-278

Adnan Januzaj (Sevilla)

Over 0.5

+170

Under 0.5

-286

Pape Gueye (Villarreal)

Over 0.5

+188

Under 0.5

-333

Juanlu Sánchez (Sevilla)

Over 0.5

+235

Under 0.5

-455

Alfonso Pedraza (Villarreal)

Over 0.5

+260

Under 0.5

-500

Dani Parejo (Villarreal)

Over 0.5

+270

Under 0.5

-556

Renato Veiga (Villarreal)

Over 0.5

+380

Under 0.5

-909

Sevilla Aiming to Get Back to Winning Ways at Home

Sevilla have not won at Estadio Ramón Sánchez Pizjuán in the past three matches. The Andalusia outfit have collected five losses, four draws and one victory in the past 10 home matches, scoring an average of 1.00 goals per game and conceding 1.70.

Villarreal have secured six victories, three defeats and one draw in the previous 10 away games, netting an average of 1.20 goals per match and conceding 1.20.

The most recent Estadio Ramón Sánchez Pizjuán meeting saw Villarreal claim a 2-1 win over Sevilla. The 6 past H2H games at Estadio Ramón Sánchez Pizjuán have involved three Sevilla victories, one draw and two Villarreal wins.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Sevilla Home Stats		1-4-5	2.70	1.00	1.70	5	5	7	3
Villarreal Away Stats		6-1-3	2.40	1.20	1.20	5	5	5	5

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

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Sevilla vs Villarreal Lineups & Team News

Before making your bets, take a look at the Sevilla vs Villarreal team news. We’ll have the predicted and confirmed La Liga lineups for you plus all the latest on player injuries.

Sevilla Team Page Villarreal Team Page