Detroit Red Wings vs Buffalo Sabres Prediction, Picks & Odds | 22 Oct 2025

NHL Betting Preview: Red Wings vs Sabres

The Detroit Red Wings go up against the Buffalo Sabres in this NHL matchup at KeyBank Center, with face-off scheduled for 19:30 on Wednesday, October 22. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, player stats, team news and the starting lineups.

There is merit in backing the Red Wings on the Moneyline considering our betting prediction is that they will beat the Sabres. Especially as -108 is available about this happening.

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Detroit Red Wings claimed a home victory in their previous game. A 4-2 triumph against Edmonton Oilers at Little Caesars Arena made it five straight wins. Dylan Larkin was on target with a hat trick and Emmitt Finnie also registered.

Buffalo Sabres have landed two home wins on the spin. It was a road defeat to Montreal Canadiens in their last game, losing 4-2 at Bell Centre. Jiri Kulich and Tyson Kozak scored one goal apiece.

Head-to-Head Statistics

The Red Wings had the edge in the most recent encounter between these teams. At Little Caesars Arena, they recorded a 7-3 win over the Sabres. The Red Wings have beaten the Sabres in the past three meetings. They’ve also claimed 6 wins in the past 10 head-to-head meetings.

Starting Goalies

John Gibson (Confirmed)

Season	W-L-OTL:	GAA:	SV%:	SO:
24/25	6-7-1	3.6	.869	0
23/24	13-27-1	3.54	.888	0

Colten Ellis (Confirmed)

Season	W-L-OTL:	GAA:	SV%:	SO:
24/25	4-3-0	3.4	.892	0

8 wins, 1 loss and 1 overtime loss, averaging 3.8 goals from 28.6 shots on goal, with a 19.4% powerplay efficiency. The Red Wings have been giving up 2.7 goals from 25.0 shots, averaging 2.4 penalties with a penalty-killing efficiency of 91.7%.

Dylan Larkin is the top points scorer with 15 points, 6 goals and 9 assists, with Lucas Raymond recording 10 points, 3 goals and 7 assists, over the last 10 games. Goalie Cam Talbot have a 2.60 goal against average with a .897 save percentage.

The Sabres have 3 wins, 6 losses and 1 overtime loss, averaging 2.6 goals from 29.6 shots on goal, with a 20.5% powerplay efficiency. They have conceded 3.5 goals from 32.3 shots, averaging 4.6 penalties per game with a penalty-killing efficiency of 93.5%.

The top points scorer is Rasmus Dahlin with 9 points, 1 goal and 8 assists, while Alex Tuch is next in line after having 8 points, 3 goals and 5 assists. Goalie Alex Lyon have a 2.55 GAA with a .924 SV%, including one shutout.

Detroit Red Wings vs Buffalo Sabres Prediction & Picks

From our key match prediction to correct score pick, top player prop insights and a builder tailored for value — our Detroit Red Wings vs Buffalo Sabres betting tips covers it all.

Game Prediction

If you’re looking for a value wager, then -108 that Detroit Red Wings win this NHL encounter certainly stands out. We’re expecting the visitors to triumph on the Moneyline at attractive odds.

The handicappers at Sportsgambler.com regularly track NHL injury updates and pair that with current form. We also tap into a deep stats database to highlight the key numbers that help shape our hockey predictions.

Key Red Wings vs Sabres stats:

• Red Wings have won 5 consecutive games.
• Red Wings have won 8 of their last 10 games.
• Red Wings have won 12 of their last 20 games.
• Sabres have lost 7 of their last 10 games.
• Sabres have lost 3 of their last 5 games.
• Sabres have lost their last 3 games against Red Wings.

Red Wings Moneyline Probability

According to the top NHL sportsbooks, there’s a 51.8% likelihood of our pick landing a return. In the opinion of our cappers, there’s actually a probability of success between 55-60%. This is why we regard this as a value bet.

If you’re looking for a wager at bigger odds, then Detroit are an option on the Puck Line. The sportsbooks have a series of betting lines that you can back them to cover.

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Our Game Prediction

Red Wings Moneyline @ -108 Bet Now

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Player Prop Picks

Top Pick: Josh Doan Over 2.5 Shots +135

Josh Doan (Sabres) has recorded Over 2.5 shots on goal in 3 straight home games. Out of all the prop bets available, we’re going to take the +135 when it comes to this Shots on Goal wager.

Correct Score Prediction

Red Wings 3 - 2 Sabres

We’ve got a correct score prediction which involves the Red Wings winning 3-2. Odds of +900 look appealing and we should get a run for our money here.

Latest Correct Score Odds

Score

Red Wings

Sabres

1-0

Red Wings

+5500

Sabres

+5500

2-0

Red Wings

+5000

Sabres

+5000

2-1

Red Wings

+1500

Sabres

+1500

3-0

Red Wings

+3500

Sabres

+3400

3-1

Red Wings

+2000

Sabres

+1900

3-2

Red Wings

+900

Sabres

+850

4-0

Red Wings

+4500

Sabres

+4000

4-1

Red Wings

+1700

Sabres

+1600

4-2

Red Wings

+1600

Sabres

+1500

4-3

Red Wings

+1050

Sabres

+1000

5-0

Red Wings

+8000

Sabres

+7000

5-1

Red Wings

+2800

Sabres

+2500

5-2

Red Wings

+1800

Sabres

+1600

5-3

Red Wings

+2400

Sabres

+2200

5-4

Red Wings

+1900

Sabres

+1900

6-0

Red Wings

+12000

Sabres

+10000

6-1

Red Wings

+6600

Sabres

+5500

6-2

Red Wings

+3400

Sabres

+3000

6-3

Red Wings

+3000

Sabres

+2800

6-4

Red Wings

+4500

Sabres

+4500

6-5

Red Wings

+4500

Sabres

+4500

7-1

Red Wings

+11000

Sabres

+9000

7-2

Red Wings

+9000

Sabres

+7500

7-3

Red Wings

+6000

Sabres

+5500

7-4

Red Wings

+6600

Sabres

+6000

7-5

Red Wings

+10000

Sabres

+10000

7-6

Red Wings

+11000

Sabres

+11000

8-1

Red Wings

+11000

Sabres

+14000

8-2

Red Wings

+14000

Sabres

+12500

8-3

Red Wings

+14000

Sabres

+12500

8-4

Red Wings

+12000

Sabres

+11000

8-5

Red Wings

+14000

Sabres

+13000

View More

Detroit Red Wings vs Buffalo Sabres Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

If you want to bet on Buffalo Sabres, then Moneyline odds of -114 are on offer, although Detroit Red Wings are a -105 chance. According to the top sportsbooks, the home team have an implied probability of 53%.

The puck line stands at 1.5 and the total goals line is 6.5. Hockey bettors regularly enjoy the opportunity to wager on Totals. The Over 6.5 selection is available to back at +108.

The best betting sites offer hundreds of game lines and team props when it comes to National Hockey League clashes. Make sure you look through all the available options before deciding which bet to place.

Moneyline

Red Wings

-105

Sabres

-114

3-Way Moneyline

Red Wings

+155

Tie

+330

Sabres

+133

Puck Line

Red Wings +1.5

-263

Sabres -1.5

+210

Total Goals

Under 6.5

-132

Over 6.5

+108

The gambling sites will have goalie and player props available for each game. Check out the various odds and take a view on whether a player’s Assists, Blocked Shots or Powerplay Points will hit over or under a certain line.

Instead of focusing on the overall outcome, some bettors prefer to look at the NHL micro betting lines. As the name suggests, it means placing short-term wagers and this might include the Next Goalscorer or Next Goal.

Latest regular season and playoff games stats.

Detroit Red Wings Stats

Buffalo Sabres Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 4 wins and 6 defeats in the last 10 games on the road

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Puck Line

• +1.5 Betting Line: Have covered the +1.5 puck line in 9 of the last 10 games
• +1.5 Betting Line on the Road: Have covered the +1.5 puck line in 6 of the last 10 games on the road

Puck Line

• -1.5 Betting Line: Have covered the -1.5 puck line in 2 of the last 10 games
• -1.5 Betting Line at Home: Have covered the -1.5 puck line in 5 of the last 10 home games

Total Goals

• Game Totals: An average of 6.50 goals in the previous 10 games
• Game Totals on the Road: An average of 6.10 goals in the previous 10 games on the road
• Over 6.5: Covered in 5 of the previous 10 games
• Over 6.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 3.80 goals and allowed 2.70 goals in the last 10 games
• Team Totals on the Road: Have scored an average of 2.80 pts and allowed 3.30 goals in the last 10 games on the road

Total Goals

• Game Totals: An average of 6.20 goals in the previous 10 games
• Game Totals at Home: An average of 6.30 goals in the previous 10 home games
• Over 6.5: Covered in 3 of the previous 10 games
• Over 6.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 2.60 goals and allowed 3.60 goals in the last 10 games
• Team Totals at Home: Have scored an average of 3.60 goals and allowed 2.70 goals in the last 10 home games

Team Stats - Avg/Game

Last 10 Games

• Goals Powerplay: 0.6
• Shots: 28.6
• Goals Shorthanded: 0
• Penalties: 2.4
• Empty Net Goals: 0.7
• Penalty Minutes: 4.8
• Blocks: 15.4
• Faceoff Wins : 26.5
• Hits: 21.1
• Giveaways: 16.4
• Takeaways: 5.1

Last 10 Games on the Road

• Goals Powerplay: 0.5
• Shots: 25
• Goals Shorthanded: 0
• Penalties: 2.5
• Empty Net Goals: 0.2
• Penalty Minutes: 5.8
• Blocks: 17.2
• Faceoff Wins : 25.6
• Hits: 21.8
• Giveaways: 14
• Takeaways: 4.5

Team Stats - Avg/Game

Last 10 Games

• Goals Powerplay: 0.8
• Shots: 29.6
• Goals Shorthanded: 0.2
• Penalties: 4.6
• Empty Net Goals: 0.2
• Penalty Minutes: 10.3
• Blocks: 15.6
• Faceoff Wins : 26.2
• Hits: 19.7
• Giveaways: 15.9
• Takeaways: 5.4

Last 10 Home Games

• Goals Powerplay: 0.6
• Shots: 31.2
• Goals Shorthanded: 0.3
• Penalties: 4.2
• Empty Net Goals: 0.3
• Penalty Minutes: 9.5
• Blocks: 15.2
• Faceoff Wins : 26
• Hits: 18
• Giveaways: 15.9
• Takeaways: 5.8

Injuries & Suspensions

Starting Lineups

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