Florida Panthers vs Buffalo Sabres Prediction, Picks & Odds | 18 Oct 2025

NHL Betting Preview: Panthers vs Sabres

The Florida Panthers battle the Buffalo Sabres in this NHL matchup at KeyBank Center, with face-off scheduled for 13:00 on Saturday, October 18. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, player stats, team news and the starting lineups.

It’s hard to pass up the Over 5.5 goals bet for this clash between the Panthers and the Sabres. Especially when you consider odds of -139 are available.

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Florida Panthers have suffered a defeat in their previous three games including a recent 3-1 loss. This occurred on the road at Prudential Center against New Jersey Devils. Evan Rodrigues was the solitary scorer after Panthers registered 22 shots.

Buffalo Sabres won their last game which was at home. It was a 8-4 triumph at KeyBank Center against Ottawa Senators. Zach Benson managed 4 points, all of them were assists.

Head-to-Head Statistics

These two teams last met at Amerant Bank Arena, with the Panthers claiming the win. Beating the Sabres by a 3-2 scoreline. The Panthers have racked up three straight victories over the Sabres. On the head-to-head front, they have won 8 of the past 10.

Starting Goalies

Sergei Bobrovsky (Confirmed)

Season	W-L-OTL:	GAA:	SV%:	SO:
24/25	14-8-1	2.8	.888	3
23/24	36-17-3	2.37	.915	6

Alex Lyon (Confirmed)

Season	W-L-OTL:	GAA:	SV%:	SO:
24/25	6-6-3	3	.905	1
23/24	21-18-4	3.05	.904	2

6 wins, 3 losses and 1 overtime loss, averaging 3.5 goals from 28.2 shots on goal, with a 20.4% powerplay efficiency. The Panthers have been giving up 2.6 goals from 26.5 shots, averaging 4.4 penalties with a penalty-killing efficiency of 90.9%.

Sam Reinhart is the top points scorer with 13 points, 9 goals and 4 assists, with Brad Marchand recording 9 points, 6 goals and 3 assists, in the last 10 games. Goalie Sergei Bobrovsky have a 1.97 goal against average with a .923 save percentage.

The Sabres have 3 wins, 6 losses and 1 overtime loss, averaging 2.6 goals from 29.2 shots on goal, with a 18.2% powerplay efficiency. They have been conceding 3.4 goals from 32.2 shots, averaging 3.7 penalties per game with a penalty-killing efficiency of 89.2%.

The top points scorer is Rasmus Dahlin with 9 points, 2 goals and 7 assists, while Alex Tuch is next in line after having 8 points, 4 goals and 4 assists. Goalie James Reimer have a 3.53 GAA with a .882 SV%, including one shutout.

Florida Panthers vs Buffalo Sabres Prediction & Picks

Discover our expert Florida Panthers vs Buffalo Sabres betting tips, featuring a key match prediction, correct score suggestion, top player prop picks and bet builder advice. Scroll down for full analysis.

Game Prediction

The -139 looks too good to miss for our pick. We’re expecting this bet to deliver when it comes to going over the goal line in this NHL encounter.

The NHL experts at Sportsgambler.com start by analyzing recent form and staying on top of injury news before making any hockey predictions. From there, we interpret the story the stats are telling to help shape our picks.

Key Panthers vs Sabres stats:

• The 5.5 line has been covered in 7 of the last 10 Panthers games on the road.
• The 5.5 line has been covered in 13 of the last 20 Panthers games.
• The 5.5 line has been covered in 11 of the last 20 Sabres games at home.

Over 5.5 Probability

Based on the odds from the top NHL sportsbooks, there’s a 58.1% likelihood of our pick delivering a return. Our experts think there’s a stronger chance of success and calculate the probability to be 65-70%. It’s the reason why we are recommending this hockey bet.

If you are wanting bigger odds for your Total bet, then it’s possible to move the line and get more juice. You can choose to wager Over when it comes to different levels.

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Our Game Prediction

Over 5.5 Goals @ -139 Bet Now

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Player Prop Picks

Top Pick: Josh Doan Over 1.5 Shots -154

Josh Doan (Sabres) has fired Over 1.5 shots on goal in 4 straight games. We’re expecting history to repeat itself and for him to cover the Shots on Goal line at odds of -154.

Correct Score Prediction

Panthers 3 - 4 Sabres

We’re going for the Sabres at +1100 to secure a 4-3 win. It’s exciting to bet on the correct score and this wager will hopefully be able to land a nice return.

Latest Correct Score Odds

Score

Panthers

Sabres

1-0

Panthers

+5000

Sabres

+5500

2-0

Panthers

+4500

Sabres

+5000

2-1

Panthers

+1400

Sabres

+1500

3-0

Panthers

+2800

Sabres

+4000

3-1

Panthers

+1700

Sabres

+2200

3-2

Panthers

+800

Sabres

+900

4-0

Panthers

+3300

Sabres

+5000

4-1

Panthers

+1300

Sabres

+2000

4-2

Panthers

+1400

Sabres

+1800

4-3

Panthers

+950

Sabres

+1100

5-0

Panthers

+5500

Sabres

+9000

5-1

Panthers

+2000

Sabres

+3400

5-2

Panthers

+1400

Sabres

+2000

5-3

Panthers

+2000

Sabres

+2800

5-4

Panthers

+1900

Sabres

+2200

6-0

Panthers

+8000

Sabres

+14000

6-1

Panthers

+4500

Sabres

+8000

6-2

Panthers

+2500

Sabres

+4000

6-3

Panthers

+2500

Sabres

+3500

6-4

Panthers

+4500

Sabres

+5500

6-5

Panthers

+4500

Sabres

+5000

7-1

Panthers

+7500

Sabres

+13000

7-2

Panthers

+6600

Sabres

+11000

7-3

Panthers

+5000

Sabres

+7500

7-4

Panthers

+6000

Sabres

+7500

7-5

Panthers

+10000

Sabres

+12000

7-6

Panthers

+11000

Sabres

+12000

8-4

Panthers

+10000

Sabres

+14000

View More

Florida Panthers vs Buffalo Sabres Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Sportsbooks’ favorites Florida Panthers are regarded as likeliest victors for this game and the -156 about them triumphing means a 61% chance based on their current Moneyline betting odds. Buffalo Sabres are the underdogs at +130 and they’re regarded as least likely to win.

The puck line is calculated to be 1.5, while total goals comes in at 5.5. Hockey fans love the chance to get an alternative angle by going for a Totals wager. If you're keen on Over 5.5, this selection is available at -130.

From team props to game lines, National Hockey League wagering comes with no shortage of options. Head to the best betting apps to discover the market that fits your read on the game.

Moneyline

Panthers

-156

Sabres

+130

3-Way Moneyline

Panthers

+104

Tie

+325

Sabres

+205

Puck Line

Panthers -1.5

+154

Sabres +1.5

-192

Total Goals

Under 5.5

+108

Over 5.5

-130

As an alternative to the team props and game lines, check out the player and goalie props that are available. These can be a fantastic alternative if you want to focus on a player’s performance. The top gambling sites will provide lots of options.

It’s possible to use stats to your advantage when it comes to NHL micro betting, especially if you’re predicting outcomes such as the Next Goal and Next Goalscorer. Check out the live team and player props and see if you can find an angle.

Latest regular season and playoff games stats.

Florida Panthers Stats

Buffalo Sabres Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Puck Line

• -1.5 Betting Line: Have covered the -1.5 puck line in 4 of the last 10 games
• -1.5 Betting Line on the Road: Have covered the -1.5 puck line in 5 of the last 10 games on the road

Puck Line

• +1.5 Betting Line: Have covered the +1.5 puck line in 5 of the last 10 games
• +1.5 Betting Line at Home: Have covered the +1.5 puck line in 7 of the last 10 home games

Total Goals

• Game Totals: An average of 6.10 goals in the previous 10 games
• Game Totals on the Road: An average of 6.60 goals in the previous 10 games on the road
• Over 5.5: Covered in 6 of the previous 10 games
• Over 5.5 on the Road: Covered in 7 of the previous 10 games on the road
• Team Totals: Have scored an average of 3.50 goals and allowed 2.60 goals in the last 10 games
• Team Totals on the Road: Have scored an average of 3.80 pts and allowed 2.80 goals in the last 10 games on the road

Total Goals

• Game Totals: An average of 6.10 goals in the previous 10 games
• Game Totals at Home: An average of 6.50 goals in the previous 10 home games
• Over 5.5: Covered in 3 of the previous 10 games
• Over 5.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 2.60 goals and allowed 3.50 goals in the last 10 games
• Team Totals at Home: Have scored an average of 3.60 goals and allowed 2.90 goals in the last 10 home games

Team Stats - Avg/Game

Last 10 Games

• Goals Powerplay: 1.1
• Shots: 28.2
• Goals Shorthanded: 0.1
• Penalties: 4.4
• Empty Net Goals: 0.3
• Penalty Minutes: 11.8
• Blocks: 16
• Faceoff Wins : 29.7
• Hits: 29.4
• Giveaways: 14.3
• Takeaways: 3.1

Last 10 Games on the Road

• Goals Powerplay: 0.8
• Shots: 26.2
• Goals Shorthanded: 0.2
• Penalties: 4.6
• Empty Net Goals: 0.3
• Penalty Minutes: 10
• Blocks: 17.8
• Faceoff Wins : 32.3
• Hits: 41.6
• Giveaways: 14.5
• Takeaways: 4.5

Team Stats - Avg/Game

Last 10 Games

• Goals Powerplay: 0.6
• Shots: 29.2
• Goals Shorthanded: 0.3
• Penalties: 3.7
• Empty Net Goals: 0.2
• Penalty Minutes: 7.7
• Blocks: 14.7
• Faceoff Wins : 25.9
• Hits: 19.6
• Giveaways: 16.6
• Takeaways: 5.1

Last 10 Home Games

• Goals Powerplay: 0.4
• Shots: 30.5
• Goals Shorthanded: 0.3
• Penalties: 3.6
• Empty Net Goals: 0.3
• Penalty Minutes: 7.5
• Blocks: 15.3
• Faceoff Wins : 24.4
• Hits: 17.3
• Giveaways: 16.5
• Takeaways: 5.7

Injuries & Suspensions

Starting Lineups

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