Arizona vs Iowa State Prediction, Picks & Odds | 27 Sep 2025
College Football Betting Preview: Arizona vs Iowa State
Arizona go up against Iowa State in this NCAAF Week 5 matchup at Jack Trice Stadium, with kickoff scheduled for 19:00 on Saturday 27 September. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.
We’re Predicting Iowa State to Cover the Line
The best betting angle could be Iowa State against the spread. You can land -105 that the market leaders are able to cover the -6.5 line and they are more than capable in their clash against Arizona.
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Both Teams Won Last Time Out
Arizona Wildcats made it three consecutive wins after a 23-17 home success over Kansas State Wildcats at Arizona Stadium.
Iowa State Cyclones got a fourth straight win in their last game. It was a 24-16 road triumph at Centennial Bank Stadium when meeting Arkansas State Red Wolves.
Quarterbacks
Noah Fifita
Rocco Becht
Arizona vs Iowa State Prediction & Picks
This Arizona vs Iowa State betting breakdown features a main match prediction, a correct score insight, expert player prop picks and a sharply constructed bet builder to guide your wagers.
Game Prediction
We’re bullish about the favorites on the spread at -6.5. Iowa State should be able to win this college football showdown by a comfortable margin and you can get odds of -105.
To deliver the best possible college football picks, we start by locking in the team news and taking time to review the latest form. There’s also no shortage of data to crunch from the most up-to-date stats available.
Key Arizona vs Iowa State stats:
Iowa State -6.5 Probability
According to the top sportsbooks, our pick has a 51.3% chance of delivering a return. After careful examination, our analysts calculate this probability to be closer to 60%. It is the reason why we are recommending this college wager.
If you’re in pursuit of bigger odds, then a Bet Builder could be a way forward. Take Iowa State to cover the line with additional selections until you’re satisfied with the price.
Get more from your bets with our detailed guide, featuring the best free bets and generous welcome bonuses.
Best Bet
Iowa State -6.5 @ -105
Player Prop Picks
The odds for Rocco Becht (Iowa State) to accumulate over 235.5 passing yards are -114. We’re happy to take him to cover the QB Passing Yards line and bettors can place this wager with confidence.
Benjamin Brahmer (Arizona) is priced at -114 to rack up over 30.5 receiving yards. We feel confident that he’ll cover the Player Receiving Yards line, which looks generous.
Same Game Parlay Picks
Get in the game with a same game parlay. Our picks are Iowa State to cover the -6.5 spread, Over 48.5 on the total and Rocco Becht (Iowa State) to have Over 235.5 passing yards.
Should you want to back different outcomes for the same game, then a football same game parlay will suit your needs. The betting sites create this personalised wagering tool where you can make different picks and combine the odds together.
Correct Score Prediction
23
-
34
Iowa State
A 34-23 win for the Cyclones is clearly a risky bet although this could be an exciting correct score option where there’s the chance to enjoy a massive potential return.
Arizona vs Iowa State Odds
The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.
Iowa State Moneyline Odds Suggest Victory
Iowa State are -233 favorites and that means a 70% chance of winning this college game according to the Moneyline betting odds with the sportsbooks. For those wanting to back Arizona, you will find +188 about the underdogs.
The spread is calculated to be 6.5, while total points comes in at 48.5. A Total bet relates to the number of points that will be scored overall. Those expecting a low total can back Under 48.5 at -110.
If you're wagering on college football, it's a good idea to visit the top betting apps and browse the extensive selection of team props and game lines. You'll find great opportunities to place bets both pre-game and in-game.
Ismail Mahdi Favorite to Score First TD
Ismail Mahdi is favorite to be First Touchdown Scorer at +490. If you want to back him to score the last TD, you can get similar odds.
Touchdown
Receiving Yards
Rushing Yards
Passing Yards
Iowa State Keep Delivering at Home
Iowa State have reeled off four in a row at Jack Trice Stadium. They own a 8-2 mark in their past 10 home games, averaging 33.60 points scored and 18.30 points allowed.
Arizona have lost three consecutive road games. They have five wins and five losses in the last 10 road games, averaging 30.50 points on offense and surrendering 31.40 on defense.
| Last 10 Games | W-L | P | PF | PA | O48.5 | U48.5 | |
|---|---|---|---|---|---|---|---|
 Iowa State Home Stats |
8-2 | 51.90 | 33.60 | 18.30 | 7 | 3 | |
 Arizona Away Stats |
5-5 | 61.90 | 30.50 | 31.40 | 8 | 2 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O48.5 = Games Over 48.5 Points
- U48.5 = Games Under 48.5 Points
Last 5 & H2H
Latest regular season and playoff games stats.
Arizona Wildcats Stats
Iowa State Cyclones Stats
- 4 wins and 6 defeats in the last 10 games
- 5 wins and 5 defeats in the last 10 games on the road
- +6.5 Betting Line: Have covered the spread in 5 of the last 10 games
- +6.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road
- -6.5 Betting Line: Have covered the spread in 4 of the last 10 games
- -6.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games
- Game Totals: An average of 52.60 pts in the previous 10 games
- Game Totals on the Road: An average of 61.90 pts in the previous 10 games on the road
- Over 48.5: Covered in 6 of the previous 10 games
- Over 48.5 on the Road: Covered in 8 of the previous 10 games on the road
- Team Totals: Have scored an average of 23.70 pts and allowed 28.90 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 30.50 pts and allowed 31.40 pts in the last 10 games on the road
- Game Totals: An average of 56.40 pts in the previous 10 games
- Game Totals at Home: An average of 51.90 pts in the previous 10 home games
- Over 48.5: Covered in 7 of the previous 10 games
- Over 48.5 at Home: Covered in 7 of the previous 10 home games
- Team Totals: Have scored an average of 31.00 pts and allowed 25.40 pts in the last 10 games
- Team Totals at Home: Have scored an average of 33.60 pts and allowed 18.30 pts in the last 10 home games
NCAAF Standings Select Season
| Big 12 | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
|
Arizona
|
3 | 0 | 111 | 26 | 85 | 3-0 | 0-0 | 3W |
BYU
|
3 | 0 | 130 | 16 | 114 | 2-0 | 1-0 | 3W |
Houston
|
3 | 0 | 98 | 29 | 69 | 2-0 | 1-0 | 3W |
|
Iowa State
|
4 | 0 | 119 | 57 | 62 | 2-0 | 2-0 | 4W |
TCU
|
3 | 0 | 125 | 59 | 66 | 2-0 | 1-0 | 3W |
Texas Tech
|
4 | 0 | 208 | 45 | 163 | 3-0 | 1-0 | 4W |
UCF
|
3 | 0 | 119 | 26 | 93 | 3-0 | 0-0 | 3W |
Kansas
|
3 | 1 | 149 | 66 | 83 | 3-0 | 0-1 | 1W |
Utah
|
3 | 1 | 147 | 59 | 88 | 1-1 | 2-0 | 1L |
Cincinnati
|
2 | 1 | 121 | 40 | 81 | 2-1 | 0-0 | 2W |
Baylor
|
2 | 2 | 138 | 117 | 21 | 1-2 | 1-0 | 1L |
Colorado
|
2 | 2 | 108 | 90 | 18 | 2-1 | 0-1 | 1W |
West Virginia
|
2 | 2 | 96 | 85 | 11 | 2-0 | 0-2 | 1L |
Oklahoma State
|
1 | 2 | 42 | 95 | -53 | 1-1 | 0-1 | 2L |
Kansas State
|
1 | 3 | 97 | 106 | -9 | 1-2 | 0-1 | 2L |
Florida State
Virginia
Betting Tips
21:00 - Fri 26 Sep
NCAAF
TCU
Arizona State
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22:30 - Fri 26 Sep
NCAAF
Houston
Oregon State
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12:00 - Sat 27 Sep
NCAAF
Rutgers
Minnesota
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12:00 - Sat 27 Sep
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USC
Illinois
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12:00 - Sat 27 Sep
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Duke
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Georgia Tech
Wake Forest
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12:00 - Sat 27 Sep
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Notre Dame
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12:00 - Sat 27 Sep
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12:00 - Sat 27 Sep
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Kansas
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12:00 - Sat 27 Sep
NCAAF
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12:45 - Sat 27 Sep
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13:00 - Sat 27 Sep
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13:30 - Sat 27 Sep
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San Martin
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