Buffalo vs Central Michigan Prediction, Picks & Odds | 12 Nov 2025
College Football Betting Preview: Buffalo vs Central Michigan
Buffalo battle Central Michigan at Kelly/Shorts Stadium, with kickoff scheduled for 19:00 on Wednesday, November 12. Our betting preview features expert NCAAF predictions, picks, the latest betting odds and H2H stats.
We are going to bet against Buffalo with our betting prediction. The best way of doing this is by siding with their opponents and we really like the -106 about Central Michigan winning on the Moneyline.
Backing Central Michigan for the W? Use the latest BetMGM promo code and read our comprehensive review for key insights.
Buffalo Bulls have won three road games on the spin, triumphing 28-3 in their previous appearance. This was against Bowling Green Falcons at Doyt L. Perry Stadium.
Central Michigan Chippewas have won three consecutive games at home. In their last appearance, they suffered a 24-21 road defeat against Western Michigan Broncos at Waldo Stadium.
Head-to-Head Statistics
Buffalo had the edge in the most recent matchup between these teams. At University of Buffalo Stadium, they recorded a 37-13 win over Central Michigan. The past 3 games between the teams have seen Buffalo win two times.
Buffalo vs Central Michigan Prediction & Picks
We bring you the complete Buffalo vs Central Michigan betting insight, including our top match prediction, correct score forecast, player prop advice and a ready-made bet builder.
Game Prediction
The -106 about Central Michigan look really attractive when it comes to the Moneyline. We think their opponents can be beaten in this college football matchup, so this is our pick.
The college football picks at Sportsgambler.com are always guided by the latest team news, injury updates and overall form. Once we've reviewed that, we dive into the most relevant stats to confidently recommend every pick.
Key Buffalo vs Central Michigan stats:
CMU Moneyline Probability
The best sportsbooks make it a 51.5% chance that our pick is settled as a winner. Taking all factors into consideration, our experts think there’s a stronger chance of success and estimate the probability to be closer to 60%. The bet can be recommended for this precise reason.
If you’re looking for greater odds, CMU can be backed at a bigger price against the spread. Also consider the option of looking at the Result & Total and Double Result lines.
Don’t miss the chance to claim free bets using our exclusive betting promo codes —check our bonus guide before placing your bets.
Player Prop Picks
You can place a bet on Joe Labas (Central Michigan) at -114 to rack up over 145.5 passing yards. With confidence, we can back him to cover the generous QB Passing Yards line, as all the signs point to him reaching the expected total.
Nik McMillan (Central Michigan) can be backed at -114 to go beyond 74.5 receiving yards. We can place a Player Receiving Yards bet with confidence, as we expect him to cover the line.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
Our same game parlay pick includes Central Michigan on the moneyline, Over 42.5 and Joe Labas (Central Michigan) to go Over 145.5 passing yards.
A same game parlay is a fantastic option for bettors who want to focus their wagering on a single football game. You can predict different outcomes and see their odds combined before going ahead and placing this tailored bet.
Correct Score Prediction
21
-
24
Central Michigan
There are massive odds available when it comes to the Chippewas claiming a 24-21 victory. A close battle is anticipated between two evenly-matched teams.
Buffalo vs Central Michigan Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
If you want to bet on Central Michigan, then Moneyline odds of -123 are on offer, although Buffalo are a +106 chance. In the eyes of the leading sportsbooks, the home team are regarded as 55% likely to claim a victory.
The spread currently stands at 1.5 and the total points line is 44.5. Having a bet on the Totals is one of the most popular football wagers. Those who wager Under 44.5 can get -115.
If you’re getting ready to place a college football bet, head over to one of the top betting apps and explore the wide variety of game lines and team props. Take your time to spot the most appealing opportunities.
Nahree Biggins is the market leader at +600 to be the First TD Scorer. Should you think he will score the final touchdown, then a similar price can be found.
Touchdown
Receiving Yards
Rushing Yards
Micro betting is something that’s really popular with bettors, with college football fans essentially being able to wager in-game when it comes to score, player and team props. Sometimes these are two-way lines where you can bet on the Next Play or Next Drive.
Central Michigan Racking Up the Home Wins
Central Michigan are riding four consecutive victories at Kelly/Shorts Stadium. They have seven wins and three losses in the last 10 games at home, averaging 30.70 points scored and 19.70 points allowed.
Buffalo have chalked up three consecutive victories on their travels. They own a 7-3 mark in their past 10 games on the road, posting 24.30 points per contest while yielding 24.60.
When the teams last met at Kelly/Shorts Stadium, Central Michigan beat Buffalo 31-27.
| Last 10 Games | W-L | P | PF | PA | O42.5 | U42.5 | |
|---|---|---|---|---|---|---|---|
 Central Michigan Home Stats |
7-3 | 50.40 | 30.70 | 19.70 | 7 | 3 | |
 Buffalo Away Stats |
7-3 | 48.90 | 24.30 | 24.60 | 7 | 3 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O42.5 = Games Over 42.5 Points
- U42.5 = Games Under 42.5 Points
Latest regular season and playoff games stats.
Buffalo Bulls Stats
Central Michigan Chippewas Stats
- 6 wins and 4 defeats in the last 10 games
- 7 wins and 3 defeats in the last 10 games on the road
- +1.5 Betting Line: Have covered the spread in 6 of the last 10 games
- +1.5 Betting Line on the Road: Have covered the spread in 7 of the last 10 games on the road
- -1.5 Betting Line: Have covered the spread in 5 of the last 10 games
- -1.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games
- Game Totals: An average of 43.20 pts in the previous 10 games
- Game Totals on the Road: An average of 48.90 pts in the previous 10 games on the road
- Over 42.5: Covered in 4 of the previous 10 games
- Over 42.5 on the Road: Covered in 7 of the previous 10 games on the road
- Team Totals: Have scored an average of 24.90 pts and allowed 18.30 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 24.30 pts and allowed 24.60 pts in the last 10 games on the road
- Game Totals: An average of 47.30 pts in the previous 10 games
- Game Totals at Home: An average of 50.40 pts in the previous 10 home games
- Over 42.5: Covered in 6 of the previous 10 games
- Over 42.5 at Home: Covered in 7 of the previous 10 home games
- Team Totals: Have scored an average of 23.30 pts and allowed 24.00 pts in the last 10 games
- Team Totals at Home: Have scored an average of 30.70 pts and allowed 19.70 pts in the last 10 home games
| Mid-American | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Western Michigan
|
9 | 4 | 307 | 237 | 70 | 6-1 | 3-3 | 5W |
Ohio
|
8 | 4 | 344 | 275 | 69 | 6-0 | 2-4 | 2W |
Toledo
|
8 | 4 | 379 | 146 | 233 | 6-0 | 2-4 | 4W |
|
Central Michigan
|
7 | 5 | 286 | 272 | 14 | 4-1 | 3-4 | 1L |
Miami (OH)
|
7 | 6 | 326 | 286 | 40 | 4-2 | 3-4 | 1L |
Akron
|
5 | 7 | 267 | 329 | -62 | 3-3 | 2-4 | 1W |
|
Buffalo
|
5 | 7 | 288 | 282 | 6 | 2-5 | 3-2 | 3L |
Kent State
|
5 | 7 | 255 | 403 | -148 | 3-2 | 2-5 | 1W |
Ball State
|
4 | 8 | 190 | 358 | -168 | 4-1 | 0-7 | 3L |
Eastern Michigan
|
4 | 8 | 289 | 357 | -68 | 3-3 | 1-5 | 1L |
Bowling Green
|
4 | 8 | 246 | 291 | -45 | 3-3 | 1-5 | 1W |
Northern Illinois
|
3 | 9 | 205 | 292 | -87 | 2-4 | 1-5 | 2L |
UMass
|
0 | 12 | 133 | 463 | -330 | 0-6 | 0-6 | 12L |
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