Duke vs Tulane Prediction, Picks & Odds | 13 Sep 2025

College Football Betting Preview: Duke vs Tulane

Duke battle Tulane in this NCAAF matchup at Yulman Stadium, with kickoff scheduled for 20:00 on Saturday 13 September. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.

Tulane Stand Out as a Great Wager

We can’t resist going for Tulane on the Moneyline, with our betting prediction made with confidence and there is -120 available that they beat Duke.

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Tulane Landed Victory in Last Game

Duke Blue Devils were beaten 45-19 at Wallace Wade Stadium in their previous game, being turned over at home to Illinois Fighting Illini.

Tulane Green Wave have triumphed in back-to-back games. The latest of these was on the road where South Alabama Jaguars were beaten 33-31 at Hancock Whitney Stadium.

Duke vs Tulane Prediction & Picks

Our Duke vs Tulane preview includes expert betting advice on all fronts — from a match prediction and correct score guidance to player prop selections and a bet builder tailored for value.

Game Prediction

Tulane should be able to outscore their opponents and our best pick is to side with them on the Moneyline. There is a tempting -120 for them to win this college football matchup.

The CFB handicappers at Sportsgambler.com start by analyzing recent form and staying on top of injury news before making any picks. From there, we interpret the story the stats are telling to help shape our predictions.

Key Duke vs Tulane stats:

• Tulane have won 4 of their last 5 games at home.
• Tulane have won 7 of their last 10 games.
• Tulane have won 2 consecutive games.
• Duke have lost 6 of their last 10 games on the road.
• Duke have lost 12 of their last 20 games on the road.

Tulane Moneyline Probability

According to the latest betting odds, our pick has a 54.6% chance of winning. Based on our analysts in-depth research, we calculate the actual probability to be closer to 60%. It's why we think it’s worth placing this college wager.

There’s a chance to wager Tulane at bigger odds against the spread. The sportsbooks will create a series of lines and you can choose the one that makes the most appeal.

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Best Bet

Tulane Moneyline @ -120 Bet Now

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Player Prop Picks

Top Pick: Darian Mensah Under 275.5 Passing Yards -114

Darian Mensah (Duke) is available at -114 to have less than 275.5 passing yards. We’re confident he’ll fall short of the QB Passing Yards line, as the total looks too high.

Latest Darian Mensah Player Prop Odds

Passing Yards

Over 275.5

-114

Under 275.5

-114

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Que'Sean Brown Under 41.5 Receiving Yards -114

Que'Sean Brown (Duke) is available at -114 to end with fewer than 41.5 receiving yards. If you agree with our verdict that the line is too high, this Player Receiving Yards wager is worth backing.

Latest Que'Sean Brown Player Prop Odds

Receiving Yards

Over 41.5

-114

Under 41.5

-114

Correct Score Prediction

Duke 28 - 30 Tulane

There might not be too much between these teams, with our correct score pick being a 30-28 victory for Tulane. There are huge odds available when it comes to this prediction.

Duke vs Tulane Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Books Predicting a Close-Run Battle

Tulane are -120 to win against Duke who are priced at betting odds of -100. According to the top sportsbooks, the home team have an implied probability of 55%.

The current spread is 1.5 and the total points line is 52.5. There is no denying the popularity of wagering on the Totals. If you’re going for Under 52.5, this outcome can be backed at -110.

If you’re getting ready to place a college football bet, head over to one of the top betting apps and explore the wide variety of game lines and team props. Take your time to spot the most appealing opportunities.

Moneyline

Duke

-100

Tulane

-120

Point Spread

Duke +1.5

-110

Tulane -1.5

-110

Total Points

Under 52.5

-110

Over 52.5

-110

Player Odds

Receiving Yards

Cooper Barkate (Duke)

Over 58.5

-114

Under 58.5

-114

Omari Hayes (Tulane)

Over 47.5

-114

Under 47.5

-114

Que'Sean Brown (Duke)

Over 41.5

-114

Under 41.5

-114

Andrel Anthony (Duke)

Over 35.5

-114

Under 35.5

-114

Bryce Bohanon (Tulane)

Over 29.5

-114

Under 29.5

-114

Rushing Yards

Maurice Turner (Tulane)

Over 48.5

-114

Under 48.5

-114

Jaquez Moore (Duke)

Over 42.5

-114

Under 42.5

-114

Tulane Sitting on Six Wins in Past Ten at Home

Tulane have six wins and four losses in the last 10 games at home, posting 31.00 points per matchup while yielding 18.00.

Duke have gone 4-6 across their last 10 road games, posting 26.00 points per contest while yielding 30.20.

Last 10 Games		W-L	P	PF	PA	O52.5	U52.5
Tulane Home Stats		6-4	49.00	31.00	18.00	5	5
Duke Away Stats		4-6	56.20	26.00	30.20	5	5

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O52.5 = Games Over 52.5 Points
• U52.5 = Games Under 52.5 Points

Last 5 & H2H

Latest regular season and playoff games stats.

Duke Blue Devils Stats

Tulane Green Wave Stats

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 4 wins and 6 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 home games

Point Spread

• +1.5 Betting Line: Have covered the spread in 6 of the last 10 games
• +1.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road

Point Spread

• -1.5 Betting Line: Have covered the spread in 7 of the last 10 games
• -1.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 56.10 pts in the previous 10 games
• Game Totals on the Road: An average of 56.20 pts in the previous 10 games on the road
• Over 52.5: Covered in 6 of the previous 10 games
• Over 52.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 26.20 pts and allowed 29.90 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 26.00 pts and allowed 30.20 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 48.40 pts in the previous 10 games
• Game Totals at Home: An average of 49.00 pts in the previous 10 home games
• Over 52.5: Covered in 4 of the previous 10 games
• Over 52.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 29.20 pts and allowed 19.20 pts in the last 10 games
• Team Totals at Home: Have scored an average of 31.00 pts and allowed 18.00 pts in the last 10 home games

NCAAF Standings Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

American Athletic	W	L	PF	PA	N. Pts	Home	Away	Strk
Memphis	2	0	83	26	57	1-0	1-0	2W
Navy	2	0	90	31	59	2-0	0-0	2W
North Texas	2	0	84	30	54	1-0	1-0	2W
South Florida	2	0	52	23	29	1-0	1-0	2W
Temple	2	0	97	17	80	1-0	1-0	2W
Tulane	2	0	56	34	22	1-0	1-0	2W
Army	1	1	51	51	0	0-1	1-0	1W
East Carolina	1	1	73	27	46	1-0	0-1	1W
Florida Atlantic	1	1	63	53	10	1-0	0-1	1W
Rice	1	1	23	47	-24	0-1	1-0	1L
Tulsa	1	1	49	28	21	1-0	0-1	1L
UAB	1	1	76	80	-4	1-0	0-1	1L
Charlotte	0	2	14	54	-40	0-2	0-0	2L
UTSA	0	2	60	85	-25	0-1	0-1	2L

Atlantic Coast	W	L	PF	PA	N. Pts	Home	Away	Strk
California	2	0	69	18	51	1-0	1-0	2W
Georgia Tech	2	0	86	32	54	1-0	1-0	2W
Louisville	2	0	79	31	48	2-0	0-0	2W
Miami	2	0	72	27	45	2-0	0-0	2W
NC State	3	0	93	72	21	2-0	1-0	3W
Pittsburgh	2	0	106	26	80	2-0	0-0	2W
Florida State	2	0	108	20	88	2-0	0-0	2W
Wake Forest	2	1	76	53	23	2-1	0-0	1L
SMU	1	1	87	61	26	1-1	0-0	1L
Virginia	1	1	79	42	37	1-0	0-1	1L
Syracuse	1	1	53	65	-12	1-0	0-1	1W
Boston College	1	1	106	52	54	1-0	0-1	1L
North Carolina	1	1	34	51	-17	0-1	1-0	1W
Duke	1	1	64	62	2	1-1	0-0	1L
Clemson	1	1	37	33	4	1-1	0-0	1W
Stanford	0	2	23	50	-27	0-0	0-2	2L
Virginia Tech	0	2	31	68	-37	0-1	0-1	2L