Eastern Michigan vs Central Michigan Prediction, Picks & Odds | 27 Sep 2025

College Football Betting Preview: Eastern Michigan vs Central Michigan

Eastern Michigan face Central Michigan in this NCAAF Week 5 matchup at Kelly/Shorts Stadium, with kickoff scheduled for 13:00 on Saturday 27 September. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.

Our Best Bet is CMU on the Spread

Don’t miss the opportunity to side with Central Michigan on the spread at -4.5. On the face of it, this seems a generous line and odds of -110 can be backed in their clash against Eastern Michigan.

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Eastern Michigan Overcame CMU in Previous Clash

Eastern Michigan Eagles have experienced back-to-back road defeats. In their previous game, they beat Louisiana Ragin Cajuns at home, winning 34-31 at Rynearson Stadium.

Central Michigan Chippewas last game saw them claim a 49-10 home win over Wagner Seahawks at Kelly/Shorts Stadium.

Head-to-Head Statistics

Eastern Michigan had the edge in the most recent matchup between these teams. At Rynearson Stadium, they recorded a 38-34 win over Central Michigan. In the past 6 H2H meetings, Central Michigan have won four.

Eastern Michigan vs Central Michigan Prediction & Picks

Step into Eastern Michigan vs Central Michigan with confidence as we bring you our main match prediction, projected scoreline and a custom-built bet builder. Dive into each section below for the latest insights.

Game Prediction

We are confident that Central Michigan will cover the spread in this college football showdown. -4.5 seems a more than generous line and you can get -110 that the favorites will win by a bigger margin.

Our team of college football handicappers track current injuries closely. Combined with recent form, this helps us identify the best value odds. A data-led approach backed by key stats and the latest team news keeps our analysis sharp.

Key Eastern Michigan vs Central Michigan stats:

• The +4.5 line hasn’t been covered by Eastern Michigan in 4 consecutive games on the road.
• The +4.5 line hasn’t been covered by Eastern Michigan in 6 of their last 10 games.

CMU -4.5 Probability

Based on the odds from the top betting apps, our pick has a 52.4% chance of landing a return. However, our analysts have this number closer to 60% based on their in-depth research. It's why we think it’s worth placing this college wager.

The sportsbooks give you the chance to buy or sell points, meaning that you can select from a variety of lines. Buying means shorter prices, with selling sending the odds upwards.

Find generous betting offers before placing your next wager. The latest free bets, promos, and welcome bonuses included.

Best Bet

Central Michigan -4.5 @ -110 Bet Now

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Correct Score Prediction

Eastern Michigan 21 - 28 Central Michigan

There are lots of different betting angles including the chance to bet on the Chippewas on the correct score lines. For example, a 28-21 win in their favor is available at huge odds.

Eastern Michigan vs Central Michigan Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Books Think CMU Likeliest to Win

Sportsbooks’ favorites Central Michigan are regarded as likeliest victors for this college game and the -192 about them triumphing means a 66% chance based on their current Moneyline betting odds. For those wanting to back Eastern Michigan, you will find +158 about the underdogs.

The spread is 4.5 and the total points line is currently 54.5. The beauty of the Totals is that you only have to choose from one of two options. If you’re going for Under 54.5, this outcome can be backed at -106.

The top sportsbooks offer a huge selection of team props and game lines when it comes to most college football games. Make sure you look through all the available options before deciding which bet to place.

Moneyline

EMU

+158

CMU

-192

Point Spread

EMU +4.5

-110

CMU -4.5

-110

Total Points

Under 54.5

-106

Over 54.5

-114

Player Props & Micro Betting

Prop betting is very popular, with bettors looking to wager on quarterback and player props such as First/Last Touchdown Scorer, Passing Yards, Player Passing Attempts, Interceptions and Kicking Points. The gambling sites will provide plenty of options.

It’s possible to use stats to your advantage when it comes to college football micro betting, especially if you’re predicting outcomes such as the Next Drive Result. Check out the live player, score and team props and see if you can find an angle.

Central Michigan Have Dominated Recent Head-to-Head Matchups at Kelly/Shorts Stadium

Central Michigan have seven wins and three losses in the last 10 games at home, putting up 29.90 points on average and giving up 21.20.

Eastern Michigan have stumbled to five consecutive losses away from home. They are 3-7 in their last 10 games on the road, posting 23.50 points per contest while yielding 32.30.

In their most recent matchup at Kelly/Shorts Stadium, Central Michigan got the better of Eastern Michigan 26-23. Across 3 head-to-head meetings at Kelly/Shorts Stadium, Central Michigan have come out on top each time.

Last 10 Games		W-L	P	PF	PA	O54.5	U54.5
Central Michigan Home Stats		7-3	51.10	29.90	21.20	4	6
Eastern Michigan Away Stats		3-7	55.80	23.50	32.30	4	6

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O54.5 = Games Over 54.5 Points
• U54.5 = Games Under 54.5 Points

Last 5 & H2H

Latest regular season and playoff games stats.

Eastern Michigan Eagles Stats

Central Michigan Chippewas Stats

Moneyline

• 2 wins and 8 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 games on the road

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +4.5 Betting Line: Have covered the spread in 4 of the last 10 games
• +4.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road

Point Spread

• -4.5 Betting Line: Have covered the spread in 1 of the last 10 games
• -4.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games

Total Points

• Game Totals: An average of 58.70 pts in the previous 10 games
• Game Totals on the Road: An average of 55.80 pts in the previous 10 games on the road
• Over 54.5: Covered in 6 of the previous 10 games
• Over 54.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 24.20 pts and allowed 34.50 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 23.50 pts and allowed 32.30 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 49.50 pts in the previous 10 games
• Game Totals at Home: An average of 51.10 pts in the previous 10 home games
• Over 54.5: Covered in 4 of the previous 10 games
• Over 54.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 18.10 pts and allowed 31.40 pts in the last 10 games
• Team Totals at Home: Have scored an average of 29.90 pts and allowed 21.20 pts in the last 10 home games

NCAAF Standings Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Mid-American	W	L	PF	PA	N. Pts	Home	Away	Strk
Bowling Green	2	2	86	94	-8	2-0	0-2	1L
Buffalo	2	2	103	78	25	1-1	1-1	1L
Central Michigan	2	2	85	132	-47	1-0	1-2	1W
Ohio	2	2	109	116	-7	2-0	0-2	1W
Toledo	2	2	134	59	75	2-0	0-2	1L
Northern Illinois	1	2	38	75	-37	1-0	0-2	2L
Akron	1	3	79	116	-37	1-1	0-2	1W
Ball State	1	3	62	133	-71	1-0	0-3	1L
Eastern Michigan	1	3	107	159	-52	1-1	0-2	1W
Kent State	1	3	73	176	-103	1-1	0-2	3L
Western Michigan	1	3	50	107	-57	1-1	0-2	1W
Massachusetts	0	3	43	116	-73	0-2	0-1	3L
Miami (OH)	0	3	55	103	-48	0-1	0-2	3L