Florida vs LSU Prediction, Picks & Odds | 13 Sep 2025

College Football Betting Preview: Florida vs LSU

Florida face off against LSU in this NCAAF matchup at Tiger Stadium, with kickoff scheduled for 19:30 on Saturday 13 September. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.

LSU Look the Smart Pick on the Spread

Our prediction is to snap up the -102 that LSU are able to cover the spread. The favorites are -7.5 in their clash against Florida and the margin of victory could be a good deal more significant.

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LSU Are 5 From 6 on the H2H

Florida Gators were beaten 18-16 at Ben Hill Griffin Stadium in their previous game, being turned over at home to South Florida.

LSU Tigers won their last game 23-7, making it successive victories. This was a home win at Tiger Stadium against Louisiana Tech Bulldogs.

Head-to-Head Statistics

The scoreline was 27-16 in favor of Florida when they last played LSU, with the matchup taking place at Ben Hill Griffin Stadium. The past 6 H2H games have seen LSU land five wins.

Quarterbacks

DJ Lagway

208.5 Passing Yards

Over -114

Under -114

Garrett Nussmeier

281.5 Passing Yards

Over -114

Under -114

Florida vs LSU Prediction & Picks

Our Florida vs LSU betting tips provide expert coverage of all major angles, including our main match prediction, top player prop picks, correct score recommendation and best bet builder insights.

Game Prediction

Our best pick is that LSU will gain the upper hand in this college football matchup. This leads us to back the favorites against the spread at -102, with the -7.5 line offering plenty of appeal.

Recent form is always part of the equation and we combine it with team news as soon as it’s available. To deliver expert predictions, our college football handicappers also analyze the latest stats to ensure we’re working with the best information possible.

Key Florida vs LSU stats:

• The -7.5 line has been covered by LSU in 3 consecutive games at home.
• The -7.5 line has been covered by LSU in 13 of their last 20 games at home.
• The -7.5 line has been covered by LSU in 6 of their last 10 games at home.

LSU -7.5 Probability

The top sportsbooks imply that our pick has a 50.5% prospect of winning. Taking all factors into consideration, our analysts think there’s a stronger chance of success and have a probability interval between 55-60%. It’s the reason why we are recommending this college bet.

In the quest to secure bigger odds, there’s the possibility of moving the line. There are plenty of choices when it comes to doing this, so you can choose the option that suits you.

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Best Bet

LSU -7.5 @ -102 Bet Now

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Player Prop Picks

Top Pick: Garrett Nussmeier Over 281.5 Passing Yards -114

Garrett Nussmeier (LSU) is priced at -114 to exceed 281.5 passing yards. We’re happy to take him to cover the QB Passing Yards line and bettors can place this wager with confidence.

Latest Garrett Nussmeier Player Prop Odds

Passing Yards

Over 281.5

-114

Under 281.5

-114

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Vernell Brown III Over 41.5 Receiving Yards -114

Vernell Brown III (Florida) is priced at -114 to go beyond 41.5 receiving yards. The line for Player Receiving Yards looks attractive and we’re confident of securing a return.

Latest Vernell Brown III Player Prop Odds

Receiving Yards

Over 41.5

-114

Under 41.5

-114

Correct Score Prediction

Florida 21 - 35 LSU

There is a speculative bet that can be enjoyed on LSU when it comes to the correct score lines. Taking them to win 35-21 should provide some entertainment.

Florida vs LSU Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

LSU Favorites to Win According to the Books

LSU have the shortest price to win this college game, with the sportsbooks giving them a 74% probability due to their -278 Moneyline betting odds. Florida are trading at bigger odds than their opponents and they can be backed at +220.

The spread currently stands at 7.5 and the total points line is 46.5. There are many ways to wager on football including the Totals. If you fancy Under 46.5, then the odds are -110.

The best betting apps provide tons of game lines and team props for nearly every college football matchup. Take a few moments to browse all the markets so you can place a bet that matches your insight.

Moneyline

Florida

+220

LSU

-278

Point Spread

Florida +7.5

-120

LSU -7.5

-102

Total Points

Under 46.5

-110

Over 46.5

-110

Player Odds

Receiving Yards

Aaron Anderson (LSU)

Over 69.5

-114

Under 69.5

-114

Barion Brown (LSU)

Over 51.5

-114

Under 51.5

-114

Eugene Wilson III (Florida)

Over 49.5

-114

Under 49.5

-114

Vernell Brown III (Florida)

Over 41.5

-114

Under 41.5

-114

Hayden Hansen (Florida)

Over 34.5

-114

Under 34.5

-114

J. Michael Sturdivant (Florida)

Over 24.5

-114

Under 24.5

-114

Zavion Thomas (LSU)

Over 22.5

-114

Under 22.5

-114

Caden Durham (LSU)

Over 16.5

-114

Under 16.5

-114

Rushing Yards

Jadan Baugh (Florida)

Over 75.5

-114

Under 75.5

-114

Caden Durham (LSU)

Over 68.5

-114

Under 68.5

-114

Passing Yards

Garrett Nussmeier (LSU)

Over 281.5

-114

Under 281.5

-114

DJ Lagway (Florida)

Over 208.5

-114

Under 208.5

-114

Can LSU Continue Strong Home Form?

LSU have reeled off three consecutive victories at Tiger Stadium. They own a 8-2 mark in their past 10 home games, putting up 30.10 points per contest and giving up 21.50.

Florida have three wins and seven losses in the last 10 games away from home, posting 26.20 points per contest while yielding 32.60.

The last time the teams met at Tiger Stadium, LSU defeated Florida 52-35. In the past 3 head-to-head meetings at Tiger Stadium, LSU have won every game.

Last 10 Games		W-L	P	PF	PA	O46.5	U46.5
LSU Home Stats		8-2	51.60	30.10	21.50	8	2
Florida Away Stats		3-7	58.80	26.20	32.60	7	3

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O46.5 = Games Over 46.5 Points
• U46.5 = Games Under 46.5 Points

Last 5 & H2H

Latest regular season and playoff games stats.

Florida Gators Stats

LSU Tigers Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• +7.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +7.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• -7.5 Betting Line: Have covered the spread in 4 of the last 10 games
• -7.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 48.40 pts in the previous 10 games
• Game Totals on the Road: An average of 58.80 pts in the previous 10 games on the road
• Over 46.5: Covered in 4 of the previous 10 games
• Over 46.5 on the Road: Covered in 7 of the previous 10 games on the road
• Team Totals: Have scored an average of 28.80 pts and allowed 19.60 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 26.20 pts and allowed 32.60 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 48.50 pts in the previous 10 games
• Game Totals at Home: An average of 52.50 pts in the previous 10 home games
• Over 46.5: Covered in 5 of the previous 10 games
• Over 46.5 at Home: Covered in 8 of the previous 10 home games
• Team Totals: Have scored an average of 26.00 pts and allowed 22.50 pts in the last 10 games
• Team Totals at Home: Have scored an average of 31.00 pts and allowed 21.50 pts in the last 10 home games

NCAAF Standings Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Southeastern	W	L	PF	PA	N. Pts	Home	Away	Strk
Arkansas	2	0	108	21	87	2-0	0-0	2W
Auburn	2	0	80	27	53	1-0	1-0	2W
Georgia	2	0	73	13	60	2-0	0-0	2W
LSU	2	0	40	17	23	1-0	1-0	2W
Mississippi State	2	0	58	37	21	1-0	1-0	2W
Missouri	2	0	103	37	66	2-0	0-0	2W
Oklahoma	2	0	59	16	43	2-0	0-0	2W
Ole Miss	2	0	93	30	63	1-0	1-0	2W
South Carolina	2	0	62	21	41	2-0	0-0	2W
Tennessee	2	0	117	43	74	2-0	0-0	2W
Texas A&M	2	0	86	46	40	2-0	0-0	2W
Vanderbilt	2	0	89	23	66	1-0	1-0	2W
Alabama	1	1	90	31	59	1-0	0-1	1W
Florida	1	1	71	18	53	1-1	0-0	1L
Kentucky	1	1	47	46	1	1-1	0-0	1L
Texas	1	1	45	21	24	1-0	0-1	1W