Illinois vs Purdue Prediction, Picks & Odds | 04 Oct 2025
College Football Betting Preview: Illinois vs Purdue
Illinois clash with Purdue in this NCAAF Week 6 matchup at Ross-Ade Stadium, with kickoff scheduled for 12:00 on Saturday, October 4. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.
Go for Illinois against the spread in order to get the best value. The favorites should be able to cover the -9.5 line at -118 when playing Purdue.
See value in our line read? Start by checking out our in-depth review of BetMGM and activate the best promo code before locking in your pick.
Illinois Fighting Illini won their previous game, beating USC Trojans at home. It was a 34-32 win at Memorial Stadium.
Purdue Boilermakers have been defeated in back-to-back games. On the road at Notre Dame Stadium, Notre Dame Fighting Irish recently beat them 56-30.
Head-to-Head Statistics
Illini beat Purdue in their last head-to-head matchup. It was a 50-49 (OT) scoreline at Memorial Stadium. It’s been four Purdue wins in the past 6 games between these teams.
Quarterbacks
Luke Altmyer
Ryan Browne
Illinois vs Purdue Prediction & Picks
Join us as we dissect the top Illinois vs Purdue betting picks — from the main match prediction and scoreline forecast to standout player props and a value-focused bet builder.
Game Prediction
We are confident that the favorites will cover the spread in this college football matchup. -9.5 seems a more than generous betting line and you can get -118 that Illinois will win by a bigger margin.
We keep a close eye on team news and our CFB handicappers stay sharp by tracking the latest form and lineups. You’ll also find a full set of stats that offer valuable insight and help shape smarter predictions ahead of the action.
Key Illinois vs Purdue stats:
Illini -9.5 Probability
The top sportsbooks imply that our pick has a 54.1% prospect of winning. Taking all factors into consideration, our cappers think there’s a stronger chance of success and estimate the probability to be closer to 60%. The wager can be recommended for this precise reason.
Want bigger odds when it comes to your point spread wager? Never fear, you are able to head to the sportsbooks and move the betting line until you’re happy with the price.
Maximize your betting experience. Explore our bonus guide for the best sportsbook promo codes, free bets, and welcome offers.
Player Prop Picks
Kaden Feagin (Illini) is priced at -161 to score a TD. We believe this is the best of the player props, with attractive odds available when it comes to betting him to score a touchdown at any time.
Devin Mockobee (Purdue) can be backed at -114 to record more than 57.5 rushing yards. The line for him on the Overs is highly appealing, with Player Rushing Yards bettors able to get plenty of juice.
Same Game Parlay Picks
Try out our same game parlay pick which starts with Illinois -9.5. We’ve also gone for Over 55.5 points and Kaden Feagin (Illinois) to be among the touchdown scorers.
A same game parlay is an awesome way of cheering on different outcomes within the same football game. You can predict a number of outcomes and get bigger odds than a single wager. The odds can combine to great effect.
Correct Score Prediction
38
-
27
Purdue
There’s the chance to land massive odds when it comes to a the Illini correct score win. We’ll try a 38-27 victory in their favor and this should be in the right ball park.
Illinois vs Purdue Odds
The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.
Sportsbooks’ favorites Illinois are regarded as likeliest victors for this college game and the -323 about them triumphing means a 76% chance based on their current Moneyline betting odds. For those wanting to back Purdue, you will find +260 about the underdogs.
7.5 is the spread and 54.5 is the total points line. There is no denying the popularity of wagering on the Totals. If you fancy Under 54.5, then the odds are -105.
If you’re getting ready to place a college football bet, head over to one of the top betting apps and explore the wide variety of game lines and team props. Take your time to spot the most appealing opportunities.
Devin Mockobee can be backed to score a touchdown at anytime at -145. He is the favorite to score the first TD at odds of +550.
Touchdown
Receiving Yards
Rushing Yards
Passing Yards
Micro betting provides a rollercoaster ride for college football bettors. It can be great to enjoy the live lines, with the opportunity to wager on the Next Scoring Play. Watch the live action before deciding which way to go.
Purdue Have Six Losses From Last Ten Home Games
Purdue own a 4-6 mark in their past 10 home games, putting up 21.30 points on average and giving up 28.50.
Illini have six wins and four losses in the last 10 games on the road, putting up 24.50 points per contest and giving up 28.90.
In their most recent matchup at Ross-Ade Stadium, Purdue got the better of Illini 44-19. From their last 3 head-to-head matchups at Ross-Ade Stadium, Purdue have collected two wins and Illini one.
| Last 10 Games | W-L | P | PF | PA | O55.5 | U55.5 | |
|---|---|---|---|---|---|---|---|
 Purdue Home Stats |
4-6 | 49.80 | 21.30 | 28.50 | 3 | 7 | |
 Illinois Away Stats |
6-4 | 53.40 | 24.50 | 28.90 | 4 | 6 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O55.5 = Games Over 55.5 Points
- U55.5 = Games Under 55.5 Points
Latest regular season and playoff games stats.
Illinois Fighting Illini Stats
Purdue Boilermakers Stats
- 8 wins and 2 defeats in the last 10 games
- 6 wins and 4 defeats in the last 10 games on the road
- -9.5 Betting Line: Have covered the spread in 5 of the last 10 games
- -9.5 Betting Line on the Road: Have covered the spread in 2 of the last 10 games on the road
- +9.5 Betting Line: Have covered the spread in 4 of the last 10 games
- +9.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games
- Game Totals: An average of 56.50 pts in the previous 10 games
- Game Totals on the Road: An average of 53.40 pts in the previous 10 games on the road
- Over 55.5: Covered in 5 of the previous 10 games
- Over 55.5 on the Road: Covered in 4 of the previous 10 games on the road
- Team Totals: Have scored an average of 33.10 pts and allowed 23.40 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 24.50 pts and allowed 28.90 pts in the last 10 games on the road
- Game Totals: An average of 51.00 pts in the previous 10 games
- Game Totals at Home: An average of 49.80 pts in the previous 10 home games
- Over 55.5: Covered in 3 of the previous 10 games
- Over 55.5 at Home: Covered in 3 of the previous 10 home games
- Team Totals: Have scored an average of 15.90 pts and allowed 35.10 pts in the last 10 games
- Team Totals at Home: Have scored an average of 21.30 pts and allowed 28.50 pts in the last 10 home games
| Big Ten | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Indiana
|
12 | 0 | 532 | 131 | 401 | 7-0 | 5-0 | 12W |
Ohio State
|
12 | 0 | 444 | 93 | 351 | 7-0 | 5-0 | 12W |
Oregon
|
11 | 1 | 458 | 178 | 280 | 6-1 | 5-0 | 6W |
Michigan
|
9 | 3 | 331 | 224 | 107 | 5-1 | 4-2 | 1L |
USC
|
9 | 3 | 438 | 269 | 169 | 7-0 | 2-3 | 1W |
Iowa
|
8 | 4 | 347 | 182 | 165 | 5-2 | 3-2 | 2W |
|
Illinois
|
8 | 4 | 352 | 279 | 73 | 6-1 | 2-3 | 1W |
Washington
|
8 | 4 | 405 | 233 | 172 | 5-2 | 3-2 | 1L |
Minnesota
|
7 | 5 | 279 | 281 | -2 | 7-0 | 0-5 | 1W |
Nebraska
|
7 | 5 | 351 | 276 | 75 | 4-3 | 3-2 | 2L |
Northwestern
|
6 | 6 | 270 | 251 | 19 | 5-2 | 1-4 | 1L |
Penn State
|
6 | 6 | 381 | 257 | 124 | 4-3 | 2-3 | 3W |
Rutgers
|
5 | 7 | 344 | 382 | -38 | 4-3 | 1-4 | 2L |
Wisconsin
|
4 | 8 | 154 | 259 | -105 | 4-3 | 0-5 | 1L |
Maryland
|
4 | 8 | 282 | 318 | -36 | 3-4 | 1-4 | 8L |
Michigan State
|
4 | 8 | 295 | 359 | -64 | 4-3 | 0-5 | 1W |
UCLA
|
3 | 9 | 218 | 401 | -183 | 2-4 | 1-5 | 5L |
|
Purdue
|
2 | 10 | 225 | 382 | -157 | 2-5 | 0-5 | 10L |
Auxerre
Metz
Predictions
11:15 - Sun 07 Dec
Ligue 1
Le Havre
Paris FC
Predictions
11:15 - Sun 07 Dec
Serie B
Empoli
Palermo
Predictions
11:30 - Sun 07 Dec
Premier League
Fulham
Crystal Palace
Predictions
11:30 - Sun 07 Dec
Bundesliga
Borussia Dortmund
Hoffenheim
Predictions
11:30 - Sun 07 Dec
Ekstraklasa
Rakow Czestochowa
Katowice
Predictions