Illinois vs Wisconsin Prediction, Picks & Odds | 22 Nov 2025

College Football Betting Preview: Illinois vs Wisconsin

Illinois face Wisconsin at Camp Randall Stadium, with kickoff scheduled for 19:30 on Saturday, November 22.

We’ve got a strong opinion when Wisconsin go up against Illinois. Our prediction is that there will be Over 41.5 points and that is available at -105 on the totals.

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Illinois Fighting Illini made it back-to-back wins after a 24-6 home success over Maryland Terrapins at Memorial Stadium.

Wisconsin Badgers were defeated in their last game. On the road, they suffered a 31-7 reverse against Indiana Hoosiers at Memorial Stadium.

Head-to-Head Statistics

It was Wisconsin who came out on top when they last played Illini. At Memorial Stadium, a 25-21 win was recorded. In the past 5 H2H meetings, Wisconsin have won three.

Illinois vs Wisconsin Prediction & Picks

Get the edge with our Illinois vs Wisconsin betting tips: a trusted match prediction, likely correct score outcome, key player prop picks and an expert-crafted bet builder.

Game Prediction

The two teams should be able to accumulate enough points for our pick to win. We’re forecasting Over 41.5 and odds of -105 are available for this college football matchup.

Our CFB handicappers start by reviewing the latest team news for each team, followed by a close look at recent form. That information is then applied to the most relevant stats to reach a well-informed verdict.

Key Illinois vs Wisconsin stats:

• The 41.5 line has been covered in the last 7 Illinois games on the road.
• The 41.5 line has been covered in 8 of the last 10 Illinois games.
• The 41.5 line has been covered in 16 of the last 20 Illinois games on the road.
• The 41.5 line has been covered in the last 2 games between these teams.

Over 41.5 Probability

Looking at the latest betting odds, our pick has a 51.3% chance of winning. However, we have this figure between 55-60% based on our in-depth research. This is why we regard this as a value wager.

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Our Game Prediction

Over 41.5 Points @ -105 Bet Now

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Player Prop Picks

Top Pick: Luke Altmyer Over 232.5 Passing Yards -114

You can back Luke Altmyer (Illini) at -114 to rack up over 232.5 passing yards. We can place a QB Passing Yards bet with confidence, as we expect him to cover the line.

Latest Luke Altmyer Player Prop Odds

Passing Yards

Over 232.5

-114

Under 232.5

-114

Rushing Yards

Over 10.5

-114

Under 10.5

-114

Correct Score Prediction

Illinois 28 - 17 Wisconsin

Rather than backing the Illini to triumph, there’s the alternative to try your luck when it comes to the correct score lines. Take a chance on a 28-17 win in their favor.

Illinois vs Wisconsin Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

The sportsbooks have Illinois at -357 when it comes to the Moneyline betting, implying the market leaders are 78% likely to win this college game according to the latest odds. At +285, Wisconsin are regarded as having a lower probability of winning.

The spread is calculated to be 8.5, while total points comes in at 41.5. Having a bet on the Totals is one of the most popular football wagers. If you're keen on Over 41.5, this selection is available at -105.

You can find a wide range of team props and game lines for every college football matchup, with the best sportsbooks creating lots of different options. Explore the pre-game and in-game selections before placing your wagers.

Moneyline

Illini

-357

Wisconsin

+285

Point Spread

Illini -8.5

-110

Wisconsin +8.5

-110

Total Points

Under 41.5

-115

Over 41.5

-105

Receiving Yards

Hank Beatty (Illini)

Over 50.5

-114

Under 50.5

-114

Hudson Clement (Illini)

Over 38.5

-114

Under 38.5

-114

Collin Dixon (Illini)

Over 34.5

-114

Under 34.5

-114

Rushing Yards

Luke Altmyer (Illini)

Over 10.5

-114

Under 10.5

-114

Wisconsin Have Suffered Six Losses in Past Ten at Home

Wisconsin own a 4-6 mark in their past 10 home games, putting up 16.70 points on average and giving up 19.20.

Illini own a 5-5 mark in their past 10 games on the road, putting up 25.90 points on average and giving up 30.80.

Illini beat Wisconsin 34-10 when the teams last met at Camp Randall Stadium.

Last 10 Games		W-L	P	PF	PA	O41.5	U41.5
Wisconsin Home Stats		4-6	35.90	16.70	19.20	2	8
Illinois Away Stats		5-5	56.70	25.90	30.80	8	2

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O41.5 = Games Over 41.5 Points
• U41.5 = Games Under 41.5 Points

Latest regular season and playoff games stats.

Illinois Fighting Illini Stats

Wisconsin Badgers Stats

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 4 wins and 6 defeats in the last 10 home games

Point Spread

• -8.5 Betting Line: Have covered the spread in 6 of the last 10 games
• -8.5 Betting Line on the Road: Have covered the spread in 3 of the last 10 games on the road

Point Spread

• +8.5 Betting Line: Have covered the spread in 3 of the last 10 games
• +8.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games

Total Points

• Game Totals: An average of 56.10 pts in the previous 10 games
• Game Totals on the Road: An average of 56.70 pts in the previous 10 games on the road
• Over 41.5: Covered in 8 of the previous 10 games
• Over 41.5 on the Road: Covered in 8 of the previous 10 games on the road
• Team Totals: Have scored an average of 32.20 pts and allowed 23.90 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 25.90 pts and allowed 30.80 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 35.20 pts in the previous 10 games
• Game Totals at Home: An average of 35.90 pts in the previous 10 home games
• Over 41.5: Covered in 2 of the previous 10 games
• Over 41.5 at Home: Covered in 2 of the previous 10 home games
• Team Totals: Have scored an average of 12.00 pts and allowed 23.20 pts in the last 10 games
• Team Totals at Home: Have scored an average of 16.70 pts and allowed 19.20 pts in the last 10 home games

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