Indiana vs Penn State Prediction, Picks & Odds | 08 Nov 2025
College Football Betting Preview: Indiana vs Penn State
Indiana battle Penn State at Beaver Stadium, with kickoff scheduled for 12:00 on Saturday, November 8. Our betting preview features expert NCAAF predictions, picks, the latest betting odds and H2H stats.
Indiana can finish well clear of Penn State and that means we’re going for the favorites against the spread. There are odds of -110 available that they are able to cover the -14.5 betting line.
Indiana Hoosiers have won their previous nine games. A 55-10 triumph recently occurred on the road at SECU Stadium when playing Maryland Terrapins.
Penn State Nittany Lions have been beaten in their last five games. On the road at Ohio Stadium, Ohio State Buckeyes recently beat them 38-14.
Head-to-Head Statistics
Penn State beat Indiana in their last head-to-head matchup. It was a 33-24 scoreline at Beaver Stadium. Penn State have won four of the past 5 games that these teams have played.
Quarterbacks
Fernando Mendoza
Ethan Grunkemeyer
Indiana vs Penn State Prediction & Picks
Take in the full Indiana vs Penn State betting outlook — from our expert match prediction and correct score pick to player prop insights and a bet builder tailored for value.
Game Prediction
Indiana at -14.5 on the spread really stand out in this college football showdown. We are prepared to bet at odds of -110 and expect them to cover this line.
Our CFB picks always start with checking the latest team news and understanding how it might impact the game. From there, we dive into the most valuable stats to uncover the insights that matter most.
Key Indiana vs Penn State stats:
Indiana -14.5 Probability
According to the best betting apps, there’s a 52.4% chance that our pick is settled as a winner. Based on our cappers in-depth research, we calculate the actual probability to be closer to 60%. That means we’re regarding it as a value bet.
If you’re looking for a good alternative to betting on Indiana on the spread, then consider the Winning Margin lines. You can choose from a range of fixed intervals and odds.
Tap into great value before you bet. Our guide rounds up today’s best free bets, promo codes and sign-up promotions.
Player Prop Picks
You can back Fernando Mendoza (Indiana) at -114 to record more than 235.5 passing yards. With confidence, we can back him to cover the generous QB Passing Yards line, as all the signs point to him reaching the expected total.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
Our same game parlay pick is Indiana -14.5 on the spread, Over 50.5 and Fernando Mendoza (Indiana) to go Over 235.5 passing yards.
We recommend a same game parlay as it’s a great way of betting on a single event. Many football bettors like to create a personalised wager which reflects their predictions for how a game is going to play out.
Correct Score Prediction
38
-
21
Penn State
For those wanting a big return from a small stake, consider the correct score lines. For example, the Hoosiers can be backed to win 38-21 at enormous betting odds.
Indiana vs Penn State Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
The sportsbooks are taking no chances with their Moneyline odds of +490 about Indiana which reflects they have a 17% chance of winning this college game. The market suggests that Penn State are least likely to win at -714.
The spread is 16.5 and the total points line is currently 52.5. Football fans love the chance to get an alternative angle by going for a Total wager. If you fancy Under 52.5, then the odds are -110.
The top sportsbooks cover every college football matchup with a great mix of game lines and team props. Whether you prefer to bet before kickoff or during the action, make sure to explore all available options.
Roman Hemby is available at -185 when it comes to Anytime Touchdown Scorer. The favorite is now priced at odds of +420 to score the first TD.
Touchdown
Receiving Yards
Rushing Yards
Passing Yards
Micro betting is an exciting way to wager on college football. There are a huge range of live lines and it’s a simple case of predicting what is going to happen next. Field Goal Outcome, Next Drive Result and Next Play Result are often among the options.
Penn State Have Owned Recent Head-to-Heads at Beaver Stadium
Penn State own a 7-3 mark in their past 10 home games, posting 33.40 points per contest while yielding 12.30.
Indiana have strung together three consecutive victories away from home. They own a 6-4 mark in their past 10 games on the road, putting up 34.30 points on average and giving up 24.00.
Penn State beat Indiana 33-24 when the teams last met at Beaver Stadium. Over the last 3 head-to-head matchups at Beaver Stadium, Penn State have claimed victory in all of them.
| Last 10 Games | W-L | P | PF | PA | O50.5 | U50.5 | |
|---|---|---|---|---|---|---|---|
 Penn State Home Stats |
7-3 | 45.70 | 33.40 | 12.30 | 4 | 6 | |
 Indiana Away Stats |
6-4 | 58.30 | 34.30 | 24.00 | 7 | 3 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O50.5 = Games Over 50.5 Points
- U50.5 = Games Under 50.5 Points
Latest regular season and playoff games stats.
Indiana Hoosiers Stats
Penn State Nittany Lions Stats
- 9 wins and 1 defeat in the last 10 games
- 6 wins and 4 defeats in the last 10 games on the road
- -14.5 Betting Line: Have covered the spread in 6 of the last 10 games
- -14.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road
- +14.5 Betting Line: Have covered the spread in 9 of the last 10 games
- +14.5 Betting Line at Home: Have covered the spread in the last 10 home games
- Game Totals: An average of 55.90 pts in the previous 10 games
- Game Totals on the Road: An average of 58.30 pts in the previous 10 games on the road
- Over 50.5: Covered in 6 of the previous 10 games
- Over 50.5 on the Road: Covered in 7 of the previous 10 games on the road
- Team Totals: Have scored an average of 43.50 pts and allowed 12.40 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 34.30 pts and allowed 24.00 pts in the last 10 games on the road
- Game Totals: An average of 52.20 pts in the previous 10 games
- Game Totals at Home: An average of 47.00 pts in the previous 10 home games
- Over 50.5: Covered in 6 of the previous 10 games
- Over 50.5 at Home: Covered in 5 of the previous 10 home games
- Team Totals: Have scored an average of 30.70 pts and allowed 21.50 pts in the last 10 games
- Team Totals at Home: Have scored an average of 33.10 pts and allowed 13.90 pts in the last 10 home games
| Big Ten | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
|
Indiana
|
13 | 0 | 545 | 141 | 404 | 7-0 | 6-0 | 13W |
Ohio State
|
12 | 1 | 454 | 106 | 348 | 7-1 | 5-0 | 1L |
Oregon
|
11 | 1 | 458 | 178 | 280 | 6-1 | 5-0 | 6W |
Michigan
|
9 | 3 | 331 | 224 | 107 | 5-1 | 4-2 | 1L |
USC
|
9 | 3 | 438 | 269 | 169 | 7-0 | 2-3 | 1W |
Iowa
|
8 | 4 | 347 | 182 | 165 | 5-2 | 3-2 | 2W |
Illinois
|
8 | 4 | 352 | 279 | 73 | 6-1 | 2-3 | 1W |
Washington
|
8 | 4 | 405 | 233 | 172 | 5-2 | 3-2 | 1L |
Minnesota
|
7 | 5 | 279 | 281 | -2 | 7-0 | 0-5 | 1W |
Nebraska
|
7 | 5 | 351 | 276 | 75 | 4-3 | 3-2 | 2L |
Northwestern
|
6 | 6 | 270 | 251 | 19 | 5-2 | 1-4 | 1L |
|
Penn State
|
6 | 6 | 381 | 257 | 124 | 4-3 | 2-3 | 3W |
Rutgers
|
5 | 7 | 344 | 382 | -38 | 4-3 | 1-4 | 2L |
Wisconsin
|
4 | 8 | 154 | 259 | -105 | 4-3 | 0-5 | 1L |
Maryland
|
4 | 8 | 282 | 318 | -36 | 3-4 | 1-4 | 8L |
Michigan State
|
4 | 8 | 295 | 359 | -64 | 4-3 | 0-5 | 1W |
UCLA
|
3 | 9 | 218 | 401 | -183 | 2-4 | 1-5 | 5L |
Purdue
|
2 | 10 | 225 | 382 | -157 | 2-5 | 0-5 | 10L |
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