Indiana vs Penn State Prediction, Picks & Odds | 08 Nov 2025

College Football Betting Preview: Indiana vs Penn State

Indiana battle Penn State at Beaver Stadium, with kickoff scheduled for 12:00 on Saturday, November 8. Our betting preview features expert NCAAF predictions, picks, the latest betting odds and H2H stats.

Big Win on the Cards for Indiana?

Indiana can finish well clear of Penn State and that means we’re going for the favorites against the spread. There are odds of -110 available that they are able to cover the -14.5 betting line.

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4 Penn State Victories in Last 5 H2H Battles

Indiana Hoosiers have won their previous nine games. A 55-10 triumph recently occurred on the road at SECU Stadium when playing Maryland Terrapins.

Penn State Nittany Lions have been beaten in their last five games. On the road at Ohio Stadium, Ohio State Buckeyes recently beat them 38-14.

Head-to-Head Statistics

Penn State beat Indiana in their last head-to-head matchup. It was a 33-24 scoreline at Beaver Stadium. Penn State have won four of the past 5 games that these teams have played.

Quarterbacks

Fernando Mendoza

235.5 Passing Yards

Over -114

Under -114

Ethan Grunkemeyer

143.5 Passing Yards

Over -114

Under -114

Indiana vs Penn State Prediction & Picks

Take in the full Indiana vs Penn State betting outlook — from our expert match prediction and correct score pick to player prop insights and a bet builder tailored for value.

Game Prediction

Indiana at -14.5 on the spread really stand out in this college football showdown. We are prepared to bet at odds of -110 and expect them to cover this line.

Our CFB picks always start with checking the latest team news and understanding how it might impact the game. From there, we dive into the most valuable stats to uncover the insights that matter most.

Key Indiana vs Penn State stats:

• The -14.5 line has been covered by Indiana in 3 consecutive games.
• The -14.5 line has been covered by Indiana in 6 of their last 9 games this season.
• The -14.5 line has been covered by Indiana in 6 of their last 10 games.

Indiana -14.5 Probability

According to the best betting apps, there’s a 52.4% chance that our pick is settled as a winner. Based on our cappers in-depth research, we calculate the actual probability to be closer to 60%. That means we’re regarding it as a value bet.

If you’re looking for a good alternative to betting on Indiana on the spread, then consider the Winning Margin lines. You can choose from a range of fixed intervals and odds.

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Best Bet

Indiana -14.5 @ -110 Bet Now

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Player Prop Picks

Top Pick: Fernando Mendoza Over 235.5 Passing Yards -114

You can back Fernando Mendoza (Indiana) at -114 to record more than 235.5 passing yards. With confidence, we can back him to cover the generous QB Passing Yards line, as all the signs point to him reaching the expected total.

Latest Fernando Mendoza Player Prop Odds

Passing Yards

Over 235.5

-114

Under 235.5

-114

Rushing Yards

Over 22.5

-114

Under 22.5

-114

Correct Score Prediction

Indiana 38 - 21 Penn State

For those wanting a big return from a small stake, consider the correct score lines. For example, the Hoosiers can be backed to win 38-21 at enormous betting odds.

Indiana vs Penn State Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Indiana Win on the Cards According to the Books

The sportsbooks are taking no chances with their Moneyline odds of -769 about Indiana which reflects they have a 88% chance of winning this college game. The market suggests that Penn State are least likely to win at +530.

The spread is 14.5 and the total points line is currently 50.5. Football fans love the chance to get an alternative angle by going for a Total wager. If you fancy Under 50.5, then the odds are -110.

The top sportsbooks cover every college football matchup with a great mix of game lines and team props. Whether you prefer to bet before kickoff or during the action, make sure to explore all available options.

Moneyline

Indiana

-769

Penn State

+530

Point Spread

Indiana -14.5

-110

Penn State +14.5

-110

Total Points

Under 50.5

-110

Over 50.5

-110

Player Odds

Receiving Yards

Kyron Hudson (Penn State)

Over 25.5

-114

Under 25.5

-114

Trebor Pena (Penn State)

Over 23.5

-114

Under 23.5

-114

Rushing Yards

Kaytron Allen (Penn State)

Over 68.5

-114

Under 68.5

-114

Roman Hemby (Indiana)

Over 64.5

-114

Under 64.5

-114

Kaelon Black (Indiana)

Over 47.5

-114

Under 47.5

-114

Fernando Mendoza (Indiana)

Over 22.5

-114

Under 22.5

-114

Passing Yards

Fernando Mendoza (Indiana)

Over 235.5

-114

Under 235.5

-114

Ethan Grunkemeyer (Penn State)

Over 143.5

-114

Under 143.5

-114

Penn State Have Owned Recent Head-to-Heads at Beaver Stadium

Penn State own a 7-3 mark in their past 10 home games, posting 33.40 points per contest while yielding 12.30.

Indiana have strung together three consecutive victories away from home. They own a 6-4 mark in their past 10 games on the road, putting up 34.30 points on average and giving up 24.00.

Penn State beat Indiana 33-24 when the teams last met at Beaver Stadium. Over the last 3 head-to-head matchups at Beaver Stadium, Penn State have claimed victory in all of them.

Last 10 Games		W-L	P	PF	PA	O50.5	U50.5
Penn State Home Stats		7-3	45.70	33.40	12.30	4	6
Indiana Away Stats		6-4	58.30	34.30	24.00	7	3

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O50.5 = Games Over 50.5 Points
• U50.5 = Games Under 50.5 Points

Last 5 & H2H

Latest regular season and playoff games stats.

Indiana Hoosiers Stats

Penn State Nittany Lions Stats

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 home games

Point Spread

• -14.5 Betting Line: Have covered the spread in 6 of the last 10 games
• -14.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road

Point Spread

• +14.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +14.5 Betting Line at Home: Have covered the spread in the last 10 home games

Total Points

• Game Totals: An average of 55.90 pts in the previous 10 games
• Game Totals on the Road: An average of 58.30 pts in the previous 10 games on the road
• Over 50.5: Covered in 6 of the previous 10 games
• Over 50.5 on the Road: Covered in 7 of the previous 10 games on the road
• Team Totals: Have scored an average of 43.50 pts and allowed 12.40 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 34.30 pts and allowed 24.00 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 52.20 pts in the previous 10 games
• Game Totals at Home: An average of 47.00 pts in the previous 10 home games
• Over 50.5: Covered in 6 of the previous 10 games
• Over 50.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 30.70 pts and allowed 21.50 pts in the last 10 games
• Team Totals at Home: Have scored an average of 33.10 pts and allowed 13.90 pts in the last 10 home games

NCAAF Standings Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big Ten	W	L	PF	PA	N. Pts	Home	Away	Strk
Indiana	9	0	418	97	321	6-0	3-0	9W
Ohio State	8	0	293	55	238	5-0	3-0	8W
Oregon	7	1	330	108	222	4-1	3-0	2W
Michigan	7	2	253	155	98	5-0	2-2	3W
Iowa	6	2	250	105	145	4-1	2-1	3W
USC	6	2	318	179	139	4-0	2-2	1W
Washington	6	2	284	167	117	4-1	2-1	1W
Minnesota	6	3	214	194	20	6-0	0-3	1W
Nebraska	6	3	297	178	119	4-2	2-1	1L
Illinois	6	3	298	233	65	4-1	2-2	1W
Northwestern	5	3	180	134	46	4-1	1-2	1L
Maryland	4	4	208	176	32	3-3	1-1	4L
Rutgers	4	5	264	280	-16	3-2	1-3	1L
UCLA	3	5	163	248	-85	2-2	1-3	1L
Penn State	3	5	252	174	78	3-2	0-3	5L
Michigan State	3	6	230	283	-53	3-2	0-4	6L
Wisconsin	2	6	100	191	-91	2-3	0-3	6L
Purdue	2	7	199	243	-44	2-3	0-4	7L