Iowa State vs Colorado Prediction, Picks & Odds | 11 Oct 2025

College Football Betting Preview: Iowa State vs Colorado

Iowa State face off against Colorado in this NCAAF Week 7 matchup at Folsom Field, with kickoff scheduled for 15:30 on Saturday 11 October. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.

Colorado to Give Iowa State a Hard Time

We’re delighted to see Colorado have been given a headstart on the spread. Take the +2.5 at -110 when they go up against Iowa State.

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Each Team Lost Previous Clash

Iowa State Cyclones were beaten in their previous game and this was on the road at Nippert Stadium. Cincinnati Bearcats claimed a 38-30 win.

Colorado Buffaloes have been defeated in back-to-back games. On the road, they recently suffered a 35-21 loss against Texas Christian Horned Frogs at Amon G. Carter Stadium.

Iowa State vs Colorado Prediction & Picks

Explore our best Iowa State vs Colorado picks, including a main match prediction, correct score forecast and a bet builder ready to use. Scroll down for full analysis.

Game Prediction

The market might have underrated Colorado in this college football showdown and -110 makes appeal considering the underdogs are +2.5 on the spread. Bet on them to cover the line.

We only make our college football picks after confirming the latest team news. Studying recent form and digging into the most relevant stats also helps us build a complete picture.

Key Iowa State vs Colorado stats:

• The +2.5 line has been covered by Colorado in 6 of their last 10 games at home.
• The +2.5 line has been covered by Colorado in 11 of their last 20 games.
• The -2.5 line hasn’t been covered by Iowa State in 3 of their last 5 games on the road.
• The -2.5 line hasn’t been covered by Iowa State in 11 of their last 20 games on the road.

Colorado +2.5 Probability

Looking at the latest betting odds, our pick has a 52.4% chance of winning. After careful examination, our experts have this probability close to 60%. That means we are regarding it as a value wager.

There are many options to buy and sell different amounts of points and effectively choose the line which makes the most appeal. It all comes down to how safe or risky you want to play things.

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Best Bet

Colorado +2.5 @ -110 Bet Now

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Correct Score Prediction

Iowa State 27 - 30 Colorado

There are massive odds available when it comes to Colorado claiming a 30-27 victory. A close battle is anticipated between two evenly-matched teams.

Iowa State vs Colorado Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Latest Odds Suggest a Close Encounter

Colorado are available at Moneyline odds of +118, while opponents Iowa State can be backed at -139. According to the top sportsbooks, the home team have an implied probability of 46%.

The current spread is 2.5 and the total points line is 51.5. A wager on the Totals allows football bettors to use the latest data to good effect. Those expecting a low total can back Under 51.5 at -110.

The top sportsbooks offer a huge selection of team props and game lines when it comes to most college football games. Make sure you look through all the available options before deciding which bet to place.

Moneyline

Iowa State

-139

Colorado

+118

Point Spread

Iowa State -2.5

-115

Colorado +2.5

-105

Total Points

Under 51.5

-110

Over 51.5

-110

Player Props & Micro Betting

As an alternative to the game lines, check out the player prop bets that are available. It’s especially great if you have a view when it comes to First, Last or Anytime Touchdown Scorer, while there are lots of other player and quarterback options.

It’s good to consider all wagering options when it comes to college football and micro betting can be an exciting way to get involved in the action. When everything goes in-game, consider whether a player will make or miss a field goal.

Colorado Count Seven Wins in Previous Ten at Home

Colorado have seven wins and three losses in the last 10 home games, putting up 34.10 points on average and giving up 21.30.

Iowa State have a 7-3 record in their last 10 games away from home, putting up 27.40 points on average and giving up 26.90.

Last 10 Games		W-L	P	PF	PA	O51.5	U51.5
Colorado Home Stats		7-3	55.40	34.10	21.30	7	3
Iowa State Away Stats		7-3	54.30	27.40	26.90	5	5

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O51.5 = Games Over 51.5 Points
• U51.5 = Games Under 51.5 Points

Last 5 & H2H

Latest regular season and playoff games stats.

Iowa State Cyclones Stats

Colorado Buffaloes Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 games on the road

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 home games

Point Spread

• -2.5 Betting Line: Have covered the spread in 7 of the last 10 games
• -2.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• +2.5 Betting Line: Have covered the spread in 4 of the last 10 games
• +2.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 55.30 pts in the previous 10 games
• Game Totals on the Road: An average of 54.30 pts in the previous 10 games on the road
• Over 51.5: Covered in 6 of the previous 10 games
• Over 51.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 30.90 pts and allowed 24.40 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 27.40 pts and allowed 26.90 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 53.20 pts in the previous 10 games
• Game Totals at Home: An average of 54.70 pts in the previous 10 home games
• Over 51.5: Covered in 6 of the previous 10 games
• Over 51.5 at Home: Covered in 6 of the previous 10 home games
• Team Totals: Have scored an average of 28.60 pts and allowed 24.60 pts in the last 10 games
• Team Totals at Home: Have scored an average of 32.40 pts and allowed 22.30 pts in the last 10 home games

NCAAF Standings Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big 12	W	L	PF	PA	N. Pts	Home	Away	Strk
BYU	5	0	192	61	131	3-0	2-0	5W
Texas Tech	5	0	243	56	187	3-0	2-0	5W
Iowa State	5	1	188	109	79	3-0	2-1	1L
Arizona	4	1	166	78	88	4-0	0-1	1W
Cincinnati	4	1	196	104	92	3-1	1-0	4W
Houston	4	1	136	88	48	2-1	2-0	1L
TCU	4	1	184	107	77	3-0	1-1	1W
Utah	4	1	195	73	122	1-1	3-0	1W
Baylor	4	2	218	178	40	2-2	2-0	2W
Kansas	4	2	210	123	87	3-1	1-1	1W
UCF	3	2	159	87	72	3-1	0-1	2L
Colorado	2	4	150	149	1	2-2	0-2	2L
Kansas State	2	4	165	161	4	2-2	0-2	1L
West Virginia	2	4	134	171	-37	2-1	0-3	3L
Oklahoma State	1	4	82	181	-99	1-2	0-2	4L