Iowa State vs Oklahoma State Prediction, Picks & Odds | 29 Nov 2025
College Football Betting Preview: Iowa State vs Oklahoma State
Iowa State battle Oklahoma State at Boone Pickens Stadium, with kickoff scheduled for 12:00 on Saturday, November 29.
We’re predicting that Iowa State will beat Oklahoma State by a significant margin. With this in mind, let’s go for the favorites at -13.5 on the spread which is currently on offer at -110.
Iowa State Cyclones beat Kansas Jayhawks in their previous game, making it back-to-back victories. It was a 38-14 home win at Jack Trice Stadium.
Oklahoma State Cowboys lost on the road in their last game, making it ten straight defeats. UCF Knights won 17-14 at Acrisure Bounce House.
Head-to-Head Statistics
It was a 34-27 win for Iowa State at Jack Trice Stadium when they last played Oklahoma State. Oklahoma State have won three of the previous 5 H2H meetings.
Quarterbacks
Rocco Becht
Zane Flores
Iowa State vs Oklahoma State Prediction & Picks
Get ready for Iowa State vs Oklahoma State with all the betting angles covered, from an expert match prediction and correct score advice to player props and a custom bet builder.
Game Prediction
We’d be surprised if the favorites don’t exceed a -13.5 spread in this college football battle. That is why the wager has to be Iowa State to cover the line at -110.
Sportsgambler.com brings strong college football expertise, built on knowing the team news as soon as it’s confirmed. Recent form plays a big part in our CFB picks and we always back it up with the most relevant stats.
Key Iowa State vs Oklahoma State stats:
Iowa State -13.5 Probability
The top betting apps make it a 52.4% chance that our pick is settled as a winner. However, our cappers think that the probability sits between 55-60% taking all factors into consideration. This college wager can therefore be backed with confidence.
A Bet Builder provides you with the opportunity to combine Iowa State on the spread with other picks. For every additional selection, the price is boosted.
Get more from your bets—review the most up-to-date betting promo codes and sign-up offers in our exclusive bonus guide.
Player Prop Picks
Abu Sama III (Iowa State) is priced at -149 to hit the end zone. We’re happy to take the odds that he’ll score at least one touchdown in the Anytime Touchdown Scorer market.
The odds for Rocco Becht (Oklahoma State) to rack up over 10.5 rushing yards are -114. We're confident in him covering the Player Rushing Yards line and hitting our Over bet.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
Take a same game parlay that incorporates Iowa State to cover the -13.5 spread along with Over 46.5 points. Add in Abu Sama III (Iowa State) as an anytime touchdown scorer.
A same game parlay is an awesome way of cheering on different outcomes within the same football game. You can predict a number of outcomes and get bigger odds than a single wager. The odds can combine to great effect.
Correct Score Prediction
38
-
17
Oklahoma State
For those wanting a big return from a small stake, consider the correct score lines. For example, the Cyclones can be backed to win 38-17 at enormous betting odds.
Iowa State vs Oklahoma State Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
The latest Moneyline betting odds give Iowa State a 87% chance of winning this college game which means they’re overwhelming -667 favorites with the sportsbooks. If you’re looking for an alternative angle, Oklahoma State are trading at +480.
The spread currently stands at 13.5 and the total points line is 46.5. A wager on the Totals allows football bettors to use the latest data to good effect. Those who wager Under 46.5 can get -115.
Consider every angle when placing your college football wagers. The best betting sites have a huge selection of team props and game lines and it’s all about finding a bet which matches your prediction of the game.
Carson Hansen can be backed to score a touchdown at anytime at -164. He is the favorite to score the first TD at odds of +370.
Touchdown
Receiving Yards
Rushing Yards
Passing Yards
Micro betting is an exciting way to wager on college football. There are a huge range of live lines and it’s a simple case of predicting what is going to happen next. Field Goal Outcome, Next Drive Result and Next Play Result are often among the options.
Oklahoma State Home Record Includes Five Straight Defeats
Oklahoma State have been handed five consecutive losses at Boone Pickens Stadium. They have one win and nine losses in the last 10 home games, averaging 20.80 points scored and 33.10 points allowed.
Iowa State own a 6-4 mark in their past 10 games on the road, posting 27.10 points per contest while yielding 29.10.
Oklahoma State beat Iowa State 20-14 when the teams last met at Boone Pickens Stadium.
| Last 10 Games | W-L | P | PF | PA | O46.5 | U46.5 | |
|---|---|---|---|---|---|---|---|
 Oklahoma State Home Stats |
1-9 | 53.90 | 20.80 | 33.10 | 6 | 4 | |
 Iowa State Away Stats |
6-4 | 56.20 | 27.10 | 29.10 | 5 | 5 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O46.5 = Games Over 46.5 Points
- U46.5 = Games Under 46.5 Points
Latest regular season and playoff games stats.
Iowa State Cyclones Stats
Oklahoma State Cowboys Stats
- 6 wins and 4 defeats in the last 10 games
- 6 wins and 4 defeats in the last 10 games on the road
- -13.5 Betting Line: Have covered the spread in 3 of the last 10 games
- -13.5 Betting Line on the Road: Have not covered the spread in any of the last 10 games on the road
- +13.5 Betting Line: Have covered the spread in 3 of the last 10 games
- +13.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games
- Game Totals: An average of 49.30 pts in the previous 10 games
- Game Totals on the Road: An average of 56.20 pts in the previous 10 games on the road
- Over 46.5: Covered in 5 of the previous 10 games
- Over 46.5 on the Road: Covered in 5 of the previous 10 games on the road
- Team Totals: Have scored an average of 28.50 pts and allowed 20.80 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 27.10 pts and allowed 29.10 pts in the last 10 games on the road
- Game Totals: An average of 50.30 pts in the previous 10 games
- Game Totals at Home: An average of 53.90 pts in the previous 10 home games
- Over 46.5: Covered in 6 of the previous 10 games
- Over 46.5 at Home: Covered in 6 of the previous 10 home games
- Team Totals: Have scored an average of 13.00 pts and allowed 37.30 pts in the last 10 games
- Team Totals at Home: Have scored an average of 20.80 pts and allowed 33.10 pts in the last 10 home games
| Big 12 | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Texas Tech
|
12 | 1 | 552 | 142 | 410 | 8-0 | 4-1 | 6W |
BYU
|
11 | 2 | 415 | 247 | 168 | 6-0 | 5-2 | 1L |
Utah
|
10 | 2 | 493 | 224 | 269 | 5-1 | 5-1 | 5W |
Arizona
|
9 | 3 | 391 | 227 | 164 | 6-1 | 3-2 | 5W |
Houston
|
9 | 3 | 340 | 262 | 78 | 3-3 | 6-0 | 1W |
|
Iowa State
|
8 | 4 | 329 | 242 | 87 | 4-2 | 4-2 | 3W |
TCU
|
8 | 4 | 369 | 302 | 67 | 5-1 | 3-3 | 2W |
Cincinnati
|
7 | 5 | 381 | 298 | 83 | 5-3 | 2-2 | 4L |
Kansas State
|
6 | 6 | 353 | 320 | 33 | 4-3 | 2-3 | 1W |
Baylor
|
5 | 7 | 373 | 391 | -18 | 3-4 | 2-3 | 3L |
Kansas
|
5 | 7 | 337 | 321 | 16 | 4-3 | 1-4 | 3L |
UCF
|
5 | 7 | 292 | 283 | 9 | 5-2 | 0-5 | 1L |
West Virginia
|
4 | 8 | 261 | 370 | -109 | 3-3 | 1-5 | 2L |
Colorado
|
3 | 9 | 251 | 366 | -115 | 3-4 | 0-5 | 5L |
|
Oklahoma State
|
1 | 11 | 170 | 400 | -230 | 1-6 | 0-5 | 11L |
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