Kentucky vs Vanderbilt Prediction, Picks & Odds | 22 Nov 2025
College Football Betting Preview: Kentucky vs Vanderbilt
Kentucky battle Vanderbilt at FirstBank Stadium, with kickoff scheduled for 15:30 on Saturday, November 22.
We are confident that Vanderbilt will cover the spread. -8.5 seems a more than generous line and you can get -110 that the Dores will win by a bigger margin when playing Kentucky.
Kentucky Wildcats claimed a home victory in their previous game. A 42-10 triumph against Tennessee Tech Golden Eagles at Kroger Field made it three straight wins.
Vanderbilt Commodores were winners last time out. Their 45-38 (OT) victory against Auburn Tigers at FirstBank Stadium was their sixth straight home triumph.
Head-to-Head Statistics
Vanderbilt won the most recent matchup between these teams. A 20-13 victory was registered against Kentucky at Kroger Field. The previous 6 H2H meetings have involved Kentucky winning four times.
Quarterbacks
Cutter Boley
Diego Pavia
Kentucky vs Vanderbilt Prediction & Picks
Be fully equipped for Kentucky vs Vanderbilt with our betting guide, offering a key match prediction, a correct score recommendation, top player prop picks and a bet builder tailored for value.
Game Prediction
It’s great to see Vanderbilt given a -8.5 line on the spread at -110 as we’re expecting a bigger margin of victory in this college football matchup.
The handicappers at Sportsgambler.com stay on top of the latest injuries, while recent form also shapes our CFB predictions. We combine this insight with up-to-date stats for sharper picks
Key Kentucky vs Vanderbilt stats:
Vandy -8.5 Probability
Based on the odds from the top sportsbooks, our pick has a 52.4% chance of winning. However, our analysts have this figure between 55-60% based on their in-depth research. The bet can be recommended for this precise reason.
There’s the chance to sell points and that means moving the line until you’re happy with your spread pick. It means a riskier bet but a bigger return on the odds available.
Don’t place a bet without checking our comprehensive guide to today’s best free bets and welcome bonuses.
Player Prop Picks
The odds for Cutter Boley (Kentucky) to finish with fewer than 201.5 passing yards are -114. He is likely to fall short of the line, making this QB Passing Yards bet an appealing option.
You can place a bet on Seth McGowan (Kentucky) at -114 to end with fewer than 58.5 rushing yards. The line looks too high and we’re confident he’ll fall short of the Player Rushing Yards total.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
Take a same game parlay that incorporates Vanderbilt to cover the -8.5 spread along with Under 54.5 points. We’ve also gone for Cutter Boley (Kentucky) to go Under 201.5 passing yards.
A football same game parlay is a single event wager where you make predictions that are going to happen in a particular game. Should a bettor get these picks correct, then they can achieve a big return from a small stake.
Correct Score Prediction
17
-
35
Vanderbilt
For those looking to get more bang for their buck, consider a correct score wager on the Dores. Backing them to win 35-17 means you can land a potential monster return.
Kentucky vs Vanderbilt Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
Vanderbilt are regarded as having a 75% chance of winning this college game according to the latest betting odds. The sportsbooks have priced them up at -303. For those wanting to back Kentucky, you will find +245 about the underdogs.
The spread is 7.5 and the total points line is currently 53.5. There is no denying the popularity of wagering on the Totals. Those who wager Under 53.5 can get -105.
The best betting apps offer a wide range of game lines and team props when it comes to most college football games. Make sure you look through all the available options before deciding which bet to place.
Favorite Diego Pavia is available at +500 to be the First TD Scorer. Similar odds apply if you’re interested in this player to score the final touchdown.
Touchdown
Receiving Yards
Rushing Yards
Passing Yards
Micro betting provides a rollercoaster ride for college football bettors. It can be great to enjoy the live lines, with the opportunity to wager on the Next Scoring Play. Watch the live action before deciding which way to go.
Vanderbilt Racking Up the Home Wins
Vanderbilt have reeled off six straight wins at FirstBank Stadium. The Dores have seven wins and three losses in the last 10 home games, averaging 34.10 points scored and 23.60 points allowed.
Kentucky own a 4-6 mark in their past 10 road games, averaging 18.50 points on offense and surrendering 24.80 on defense.
Kentucky defeated Vanderbilt 45-28 the last time they played at FirstBank Stadium. Across 3 head-to-head meetings at FirstBank Stadium, Kentucky have come out on top each time.
| Last 10 Games | W-L | P | PF | PA | O54.5 | U54.5 | |
|---|---|---|---|---|---|---|---|
 Vanderbilt Home Stats |
7-3 | 57.70 | 34.10 | 23.60 | 5 | 5 | |
 Kentucky Away Stats |
4-6 | 43.30 | 18.50 | 24.80 | 2 | 8 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O54.5 = Games Over 54.5 Points
- U54.5 = Games Under 54.5 Points
Latest regular season and playoff games stats.
Kentucky Wildcats Stats
Vanderbilt Commodores Stats
- 5 wins and 5 defeats in the last 10 games
- 4 wins and 6 defeats in the last 10 games on the road
- +8.5 Betting Line: Have covered the spread in 7 of the last 10 games
- +8.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road
- -8.5 Betting Line: Have covered the spread in 5 of the last 10 games
- -8.5 Betting Line at Home: Have covered the spread in 3 of the last 10 home games
- Game Totals: An average of 49.00 pts in the previous 10 games
- Game Totals on the Road: An average of 43.30 pts in the previous 10 games on the road
- Over 54.5: Covered in 2 of the previous 10 games
- Over 54.5 on the Road: Covered in 2 of the previous 10 games on the road
- Team Totals: Have scored an average of 25.90 pts and allowed 23.10 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 18.50 pts and allowed 24.80 pts in the last 10 games on the road
- Game Totals: An average of 60.50 pts in the previous 10 games
- Game Totals at Home: An average of 60.10 pts in the previous 10 home games
- Over 54.5: Covered in 6 of the previous 10 games
- Over 54.5 at Home: Covered in 6 of the previous 10 home games
- Team Totals: Have scored an average of 38.30 pts and allowed 22.20 pts in the last 10 games
- Team Totals at Home: Have scored an average of 35.20 pts and allowed 24.90 pts in the last 10 home games
| Southeastern | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Georgia
|
12 | 1 | 415 | 207 | 208 | 6-1 | 6-0 | 9W |
Ole Miss
|
11 | 1 | 447 | 241 | 206 | 8-0 | 3-1 | 5W |
Texas A&M
|
11 | 1 | 436 | 263 | 173 | 7-0 | 4-1 | 1L |
Oklahoma
|
10 | 2 | 317 | 167 | 150 | 6-1 | 4-1 | 4W |
|
Vanderbilt
|
10 | 2 | 473 | 263 | 210 | 7-0 | 3-2 | 3W |
Alabama
|
10 | 3 | 406 | 226 | 180 | 6-2 | 4-1 | 1L |
Texas
|
9 | 3 | 355 | 237 | 118 | 7-0 | 2-3 | 2W |
Missouri
|
8 | 4 | 386 | 233 | 153 | 6-2 | 2-2 | 1W |
Tennessee
|
8 | 4 | 489 | 345 | 144 | 5-3 | 3-1 | 1L |
LSU
|
7 | 5 | 262 | 220 | 42 | 6-1 | 1-4 | 1L |
|
Kentucky
|
5 | 7 | 276 | 317 | -41 | 4-3 | 1-4 | 2L |
Auburn
|
5 | 7 | 321 | 248 | 73 | 3-4 | 2-3 | 1L |
Mississippi State
|
5 | 7 | 366 | 350 | 16 | 3-4 | 2-3 | 3L |
Florida
|
4 | 8 | 259 | 288 | -29 | 4-3 | 0-5 | 1W |
South Carolina
|
4 | 8 | 272 | 265 | 7 | 4-4 | 0-4 | 1L |
Arkansas
|
2 | 10 | 395 | 406 | -11 | 2-5 | 0-5 | 10L |
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