Liberty vs Old Dominion Prediction, Picks & Odds | 27 Sep 2025

College Football Betting Preview: Liberty vs Old Dominion

Liberty lock horns with Old Dominion in this NCAAF Week 5 matchup at S.B. Ballard Stadium, with kickoff scheduled for 18:00 on Saturday 27 September. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.

An Easy Win for Old Dominion?

Old Dominion can enjoy a huge win and a bet on the spread could be the best way forward. Back the favorites off -15.5 at -104 to cover the line against Liberty.

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38-10 Win for Liberty in Pair’s Last Encounter

Liberty Flames have lost in their previous three outings. In a recent home game at Williams Stadium, they were turned over 31-13 by James Madison Dukes.

Old Dominion Monarchs made it back-to-back wins in their last game. It was a 45-26 road triumph at Lane Stadium when meeting Virginia Tech Hokies.

Head-to-Head Statistics

Liberty won the most recent matchup between these teams. A 38-10 victory was registered against Old Dominion at Williams Stadium. In the past 3 meetings between these teams, Liberty have won all of them.

Liberty vs Old Dominion Prediction & Picks

The Liberty vs Old Dominion betting tips feature sharp analysis across major markets, including a key match prediction, correct score guidance and a ready-made bet builder.

Game Prediction

Old Dominion can finish well clear in this college football battle and that means we’re going for them against the spread. There is -104 on offer that the favorites are able to cover a -15.5 line.

We closely track recent form and look for patterns that may impact the outcome. The same goes for injuries to key players. When combined with the most relevant stats, this gives us a strong foundation for accurate CFB picks.

Key Liberty vs Old Dominion stats:

• The -15.5 line has been covered by Old Dominion in 2 consecutive games.

Old Dominion -15.5 Probability

If you go by the top betting apps, there’s a 51% chance that our pick is settled as a winner. However, we think that the probability is close to 60% taking all factors into consideration. The wager can be recommended for this precise reason.

We recommend moving the line if you are searching for bigger odds about the same selection. Take your spread pick and get the juice that you want from your bet in the process.

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Best Bet

Old Dominion -15.5 @ -104 Bet Now

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Correct Score Prediction

Liberty 20 - 42 Old Dominion

There are some huge returns lying in wait if you can get the correct score right. With this in mind, we’ll have a play on Old Dominion to enjoy a 42-20 winning scoreline.

Liberty vs Old Dominion Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Old Dominion Heavy Favorites in Eyes of the Books

The latest Moneyline betting odds give Old Dominion a 86% chance of winning this college game which means they’re overwhelming -625 favorites with the sportsbooks. Liberty are regarded as a long shot to win and you can currently back them at +440.

The spread is 15.5 and the total points line is currently 52.5. Football fans love the chance to get an alternative angle by going for a Total wager. Those expecting a low total can back Under 52.5 at -105.

Make sure to explore all angles before placing your college football bets. The top sportsbooks offer a wide range of game lines and team props and it’s all about finding a wager which matches your prediction of the matchup.

Moneyline

Liberty

+440

Old Dominion

-625

Point Spread

Liberty +15.5

-118

Old Dominion -15.5

-104

Total Points

Under 52.5

-105

Over 52.5

-115

Player Props & Micro Betting

If you’re looking for an alternative to the main game lines, check out the player props instead. It’s great to bet on Quarterback Passing Yards, First Touchdown Scorer and Passing Touchdowns as potential options.

For those looking to enjoy a thrilling in-game wager, then college football micro betting could be up your street. You are now able to wager on what will happen on the next snap by staking your money on the Next Play Result.

Old Dominion Have Suffered Six Defeats in Their Last Ten at Home

Old Dominion own a 4-6 mark in their past 10 home games, putting up 30.70 points on average and giving up 26.30.

Liberty have endured three straight defeats on the road. They have gone 5-5 across their last 10 road games, posting 27.10 points per contest while yielding 28.10.

Liberty earned a 38-24 win over Old Dominion the last time they played at S.B. Ballard Stadium.

Last 10 Games		W-L	P	PF	PA	O52.5	U52.5
Old Dominion Home Stats		4-6	57.00	30.70	26.30	6	4
Liberty Away Stats		5-5	55.20	27.10	28.10	6	4

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O52.5 = Games Over 52.5 Points
• U52.5 = Games Under 52.5 Points

Last 5 & H2H

Latest regular season and playoff games stats.

Liberty Flames Stats

Old Dominion Monarchs Stats

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 4 wins and 6 defeats in the last 10 home games

Point Spread

• +15.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +15.5 Betting Line on the Road: Have covered the spread in 9 of the last 10 games on the road

Point Spread

• -15.5 Betting Line: Have covered the spread in 3 of the last 10 games
• -15.5 Betting Line at Home: Have covered the spread in 2 of the last 10 home games

Total Points

• Game Totals: An average of 47.80 pts in the previous 10 games
• Game Totals on the Road: An average of 55.20 pts in the previous 10 games on the road
• Over 52.5: Covered in 4 of the previous 10 games
• Over 52.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 23.40 pts and allowed 24.40 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 27.10 pts and allowed 28.10 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 57.50 pts in the previous 10 games
• Game Totals at Home: An average of 57.00 pts in the previous 10 home games
• Over 52.5: Covered in 6 of the previous 10 games
• Over 52.5 at Home: Covered in 6 of the previous 10 home games
• Team Totals: Have scored an average of 33.20 pts and allowed 24.30 pts in the last 10 games
• Team Totals at Home: Have scored an average of 30.70 pts and allowed 26.30 pts in the last 10 home games

NCAAF Standings Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Sun Belt	W	L	PF	PA	N. Pts	Home	Away	Strk
Texas State	3	1	145	100	45	2-0	1-1	1W
Appalachian State	2	1	76	62	14	1-0	1-1	1L
James Madison	2	1	90	51	39	1-0	1-1	1W
Old Dominion	2	1	113	59	54	1-0	1-1	2W
UL Monroe	2	1	60	98	-38	1-0	1-1	1W
Coastal Carolina	2	2	58	106	-48	1-1	1-1	1W
Georgia Southern	2	2	120	152	-32	2-0	0-2	2W
Marshall	2	2	107	101	6	1-1	1-1	2W
Southern Miss	2	2	113	106	7	2-1	0-1	1L
Troy State	2	2	82	92	-10	1-1	1-1	1W
Georgia State	1	3	81	192	-111	1-1	0-2	1L
Arkansas State	1	3	93	132	-39	1-1	0-2	3L
Louisiana	1	3	87	110	-23	1-1	0-2	2L
South Alabama	1	3	104	123	-19	1-2	0-1	3L

Conference USA	W	L	PF	PA	N. Pts	Home	Away	Strk
Delaware Blue Hens	3	1	124	105	19	2-0	1-1	2W
Louisiana Tech	3	1	110	57	53	3-0	0-1	2W
Western Kentucky	3	1	148	91	57	3-0	0-1	1W
New Mexico St	2	1	54	66	-12	2-0	0-1	1L
FIU	2	2	96	109	-13	2-1	0-1	1L
Jacksonville State	2	2	123	92	31	2-0	0-2	1W
Kennesaw State	2	2	73	100	-27	2-0	0-2	2W
Missouri State	2	2	86	131	-45	1-1	1-1	1W
Liberty	1	3	78	95	-17	1-1	0-2	3L
M. Tennessee	1	3	66	131	-65	0-2	1-1	1L
UTEP	1	3	93	103	-10	1-1	0-2	2L
Sam Houston	0	4	65	171	-106	0-1	0-3	4L