LSU vs Houston Prediction, Picks & Odds | 27 Dec 2025

College Football Betting Preview: LSU vs Houston

LSU go up against Houston at NRG Stadium, with kickoff scheduled for 21:15 on Saturday, December 27.

The betting prediction is to back Houston at -133. We think that LSU are massively opposable, so this is the best angle of attack with our wager.

Think Houston has the edge? Check out our expert review of BetMGM before claiming the latest promo code on offer.

LSU Tigers have now lost four straight road games. In their previous game, Oklahoma Sooners won 17-13 at Gaylord Family Memorial Stadium.

Houston Cougars have lost back-to-back at home. Their last game saw them land a 31-24 road victory at McLane Stadium against Baylor Bears.

LSU vs Houston Prediction & Picks

Our expert LSU vs Houston betting tips include a main match prediction, a correct score pick and bet builder advice. Explore each section below for detailed insights.

Game Prediction

There is -133 available when it comes to Houston on the Moneyline. We believe that our pick has a strong chance of winning this college football showdown and the odds makes plenty of appeal.

Team news plays a key role in our college football forecasts and we’re always tracking players with injury concerns. We also stay on top of the form guide, supported by detailed stats that help paint a clearer picture of what to expect

Key LSU vs Houston stats:

• Houston have won 9 of their last 12 games this season.
• Houston have won 7 of their last 10 games.
• LSU have lost 3 of their last 5 games.

Houston Moneyline Probability

If you go by the top betting apps, there’s a 57.1% chance that our pick is settled as a winner. After careful examination, our cappers have this probability somewhere between 60-65%. It’s why we think it’s worth placing this college bet.

If you’re wanting bigger odds about Houston, then there are a number of viable alternatives including the Spread, Double Result and the Result & Total lines.

Make your bet go further. Browse our updated guide packed with the best free bets, sign-up offers and betting bonuses.

Our Game Prediction

Houston Moneyline @ -133 Bet Now

BetMGM Promo Up To $1500 in Bonus Bets Get Bonus T&C apply. Gamble responsibly 18+

Gamble responsibly 18+. All odds are correct at time of publishing and are subject to change. To use the Bookmaker Live Streaming services you will need to be logged in and have a funded account or to have placed a bet in the last 24 hours. Geo-restrictions apply.

Correct Score Prediction

LSU 23 - 24 Houston

We’re expecting this to be a close matchup and we’ll take the Coogs to win 24-23. This is available at massive odds for those that want to have a speculative wager.

LSU vs Houston Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

The Moneyline odds about Houston triumphing is priced at -133 and you can get LSU at +114. The hosts have a 57% chance of victory in the eyes of the leading sportsbooks.

There is a spread of 2.5 and total points has a line of 41.5. A Total bet relates to the number of points that will be scored overall. If you want to bet Under 41.5, there are odds of -115.

The top sportsbooks cover every college football matchup with a great mix of game lines and team props. Whether you prefer to bet before kickoff or during the action, make sure to explore all available options.

Moneyline

LSU

+114

Houston

-133

Point Spread

LSU +2.5

-105

Houston -2.5

-115

Total Points

Under 41.5

-115

Over 41.5

-105

You shouldn’t overlook the player props when it comes to betting on individual games. Many gambling sites will give you the chance to get with or bet against a specific player or quarterback when it comes to number of Touchdowns, Passing or Rushing Yards.

There are lots of exciting college football micro betting lines that are created and they are available in-game. Among them are whether a field goal will be scored and you simply bet whether the player will make it or miss.

Latest regular season and playoff games stats.

LSU Tigers Stats

Houston Cougars Stats

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 home games

Point Spread

• +2.5 Betting Line: Have covered the spread in 5 of the last 10 games
• +2.5 Betting Line on the Road: Have covered the spread in 3 of the last 10 games on the road

Point Spread

• -2.5 Betting Line: Have covered the spread in 7 of the last 10 games
• -2.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games

Total Points

• Game Totals: An average of 42.50 pts in the previous 10 games
• Game Totals on the Road: An average of 47.10 pts in the previous 10 games on the road
• Over 41.5: Covered in 5 of the previous 10 games
• Over 41.5 on the Road: Covered in 7 of the previous 10 games on the road
• Team Totals: Have scored an average of 22.20 pts and allowed 20.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 21.90 pts and allowed 25.20 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 53.10 pts in the previous 10 games
• Game Totals at Home: An average of 42.30 pts in the previous 10 home games
• Over 41.5: Covered in 8 of the previous 10 games
• Over 41.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 27.80 pts and allowed 25.30 pts in the last 10 games
• Team Totals at Home: Have scored an average of 20.50 pts and allowed 21.80 pts in the last 10 home games

Top American Football Pages