LSU vs Vanderbilt Prediction, Picks & Odds | 18 Oct 2025
College Football Betting Preview: LSU vs Vanderbilt
LSU clash with Vanderbilt in this NCAAF Week 8 clash at FirstBank Stadium, with kickoff scheduled for 12:00 on Saturday 18 October. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.
Back Vandy to Have the Edge
There is -135 available when it comes to Vanderbilt on the Moneyline and we’re expecting them to beat LSU. There’s plenty of juice when it comes to backing our prediction.
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Teams’ Previous H2H Saw 24-17 LSU Victory
LSU Tigers won their previous game which was at home. It was a 20-10 triumph at Tiger Stadium against South Carolina Gamecocks.
Vanderbilt Commodores have won three consecutive games at home. In their last appearance, they suffered a 30-14 road defeat against Alabama Crimson Tide at Bryant-Denny Stadium.
Head-to-Head Statistics
The scoreline was 24-17 in favor of LSU when they last played Vanderbilt, with the matchup taking place at Tiger Stadium. It’s been a succession of LSU wins in the past 3 H2H meetings.
Quarterbacks


LSU vs Vanderbilt Prediction & Picks
We dive into the best LSU vs Vanderbilt betting angles, including an expert match prediction, correct score forecast, top player prop bets and a value-focused bet builder.
Game Prediction
The best pick is that Vanderbilt will outscore their opponents, with odds of -135 currently available that they win this college football battle. That looks a price worth taking on this value selection.
Our CFB predictions are always well-researched, starting with a combination of the latest team news and current form. Once we’ve got a solid read on the matchup, we layer in the key data to back it up.
Key LSU vs Vanderbilt stats:
Vandy Moneyline Probability
According to the best betting apps, there’s a 57.5% chance that our pick is settled as a winner. Based on our cappers in-depth research, we calculate the actual probability to be 60-65%. It is therefore regarded as a value bet.
If you’re looking for a wager at bigger odds, then Vandy on the Double Result lines could be a good way forward. You need them to lead at the halfway stage and then claim a win.
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Best Bet
Vanderbilt Moneyline @ -135
Player Prop Picks
Garrett Nussmeier (LSU) is available at -114 to have less than 257.5 passing yards. He is likely to fall short of the line, making this QB Passing Yards bet an appealing option.


The odds for Eli Stowers (Vanderbilt) to end with fewer than 52.5 receiving yards stand at -114. We're confident he’ll fall short of the Player Receiving Yards line, so we're backing the Under.


Same Game Parlay Picks
Check out this same game parlay which starts with Vanderbilt on the moneyline. We’ve also gone for Over 48.5 points and Garrett Nussmeier (LSU) to go Under 257.5 passing yards.
A football same game parlay is a single event wager where you make predictions that are going to happen in a particular game. Should a bettor get these picks correct, then they can achieve a big return from a small stake.
Correct Score Prediction
LSU vs Vanderbilt Odds
The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.
Moneyline Odds Suggest a Close Contest
Vanderbilt have been given Moneyline odds of -120 against LSU who are +102. According to the top sportsbooks, the home team have an implied probability of 55%.
The spread is currently 1.5, with the total points line at 48.5. There are many ways to wager on football including the Totals. If you fancy Over 48.5, this outcome can be backed at -110.
The top sportsbooks cover every college football matchup with a great mix of game lines and team props. Whether you prefer to bet before kickoff or during the action, make sure to explore all available options.




Caden Durham Favorite to Be First TD Scorer
The First TD Scorer favorite is Caden Durham at +500. Similar odds can be found if you’re interested in this player to record the last touchdown.
Touchdown




Receiving Yards




Rushing Yards




Passing Yards



Micro Betting
Among the various options for wagering on college football, you will find that micro betting is provided. It focuses on short-term in-game outcomes such as whether a touchdown will be scored within the next few minutes.

Vanderbilt Rolling at Home
Vanderbilt have put together three consecutive victories at FirstBank Stadium. They own a 7-3 mark in their past 10 home games, averaging 37.70 points on offense and surrendering 22.60 on defense.
LSU own a 5-5 mark in their past 10 games on the road, putting up 31.20 points on average and giving up 29.20.
The last time LSU faced Vanderbilt at FirstBank Stadium, they won 41-7.
Last 10 Games | W-L | P | PF | PA | O48.5 | U48.5 | |
---|---|---|---|---|---|---|---|
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7-3 | 60.30 | 37.70 | 22.60 | 7 | 3 | |
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5-5 | 60.40 | 31.20 | 29.20 | 6 | 4 |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O48.5 = Games Over 48.5 Points
- U48.5 = Games Under 48.5 Points
Last 5 & H2H
Latest regular season and playoff games stats.


- 8 wins and 2 defeats in the last 10 games
- 5 wins and 5 defeats in the last 10 games on the road
- +2.5 Betting Line: Have covered the spread in 8 of the last 10 games
- +2.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road
- -2.5 Betting Line: Have covered the spread in 6 of the last 10 games
- -2.5 Betting Line at Home: Have covered the spread in 7 of the last 10 home games
- Game Totals: An average of 43.90 pts in the previous 10 games
- Game Totals on the Road: An average of 60.40 pts in the previous 10 games on the road
- Over 48.5: Covered in 3 of the previous 10 games
- Over 48.5 on the Road: Covered in 6 of the previous 10 games on the road
- Team Totals: Have scored an average of 27.60 pts and allowed 16.30 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 31.20 pts and allowed 29.20 pts in the last 10 games on the road
- Game Totals: An average of 57.20 pts in the previous 10 games
- Game Totals at Home: An average of 60.40 pts in the previous 10 home games
- Over 48.5: Covered in 5 of the previous 10 games
- Over 48.5 at Home: Covered in 7 of the previous 10 home games
- Team Totals: Have scored an average of 34.10 pts and allowed 23.10 pts in the last 10 games
- Team Totals at Home: Have scored an average of 37.80 pts and allowed 22.60 pts in the last 10 home games
NCAAF Standings Select Season
Southeastern | W | L | PF | PA | N. Pts | Home | Away | Strk |
---|---|---|---|---|---|---|---|---|
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7 | 0 | 253 | 164 | 89 | 5-0 | 2-0 | 7W |
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6 | 1 | 246 | 124 | 122 | 4-0 | 2-1 | 6W |
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6 | 1 | 236 | 137 | 99 | 4-1 | 2-0 | 3W |
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6 | 1 | 273 | 117 | 156 | 5-1 | 1-0 | 1W |
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6 | 1 | 201 | 66 | 135 | 4-0 | 2-1 | 1W |
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6 | 1 | 262 | 158 | 104 | 5-0 | 1-1 | 1L |
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6 | 1 | 290 | 140 | 150 | 4-0 | 2-1 | 1W |
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5 | 2 | 179 | 102 | 77 | 4-0 | 1-2 | 1L |
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5 | 2 | 309 | 213 | 96 | 4-1 | 1-1 | 1L |
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5 | 2 | 187 | 79 | 108 | 4-0 | 1-2 | 2W |
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4 | 3 | 223 | 142 | 81 | 3-1 | 1-2 | 3L |
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3 | 4 | 165 | 125 | 40 | 2-2 | 1-2 | 4L |
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3 | 4 | 157 | 140 | 17 | 3-1 | 0-3 | 1W |
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3 | 4 | 141 | 140 | 1 | 3-2 | 0-2 | 2L |
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2 | 4 | 135 | 155 | -20 | 2-2 | 0-2 | 3L |
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2 | 5 | 260 | 229 | 31 | 2-2 | 0-3 | 5L |

















