Miami (OH) vs Buffalo Prediction, Picks & Odds | 19 Nov 2025

College Football Betting Preview: Miami-Ohio vs Buffalo

Miami-Ohio face Buffalo at University of Buffalo Stadium, with kickoff scheduled for 19:00 on Wednesday, November 19.

The total line of 39.5 points looks pretty low and we can take advantage by backing the Overs at -110. We can see Buffalo and Miami-Ohio combining to go bigger.

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Miami-Ohio Redhawks have suffered back-to-back defeats, recently being beaten at home by Toledo Rockets 24-3 at Fred Yager Stadium.

Buffalo Bulls were defeated in their last game. On the road, they suffered a 38-19 reverse against Central Michigan Chippewas at Kelly/Shorts Stadium.

Head-to-Head Statistics

It was a 23-10 win for Miami-Ohio at Fred Yager Stadium when they last played Buffalo. The previous 5 H2H meetings have involved Miami-Ohio winning three times.

Miami (OH) vs Buffalo Prediction & Picks

Prepare for Miami (OH) vs Buffalo with our expert betting guide featuring a trusted match prediction, a correct score recommendation and a well-crafted bet builder.

Game Prediction

The two teams are capable of exceeding the set points total line which leads us to predict Over 39.5 as a value wager at -110 for this college football matchup.

Our team of college football handicappers track current injuries closely. Combined with recent form, this helps us identify the best value odds. A data-led approach backed by key stats and the latest team news keeps our analysis sharp.

Key Miami-Ohio vs Buffalo stats:

• The 39.5 line has been covered in 7 of the last 10 Miami (OH) games on the road.
• The 39.5 line has been covered in 14 of the last 20 Miami (OH) games.
• The 39.5 line has been covered in 4 of the last 5 Buffalo games.
• The 39.5 line has been covered in 15 of the last 20 Buffalo games.
• The 39.5 line has been covered in the last 2 Buffalo games at home.

Over 39.5 Probability

When you look at the latest odds, our pick has a 52.4% chance of delivering a return. However, our analysts in-depth research has found that the actual probability is closer to 60%. This is why we can recommend this college bet.

There are ways to boost the odds on an Over wager and some bettors go down the Bet Builder route. It’s effectively a same game parlay where you throw in other picks.

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Our Game Prediction

Over 39.5 Points @ -110 Bet Now

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Correct Score Prediction

Miami (OH) 24 - 21 Buffalo

For a fun bet, consider backing Miami (OH) to claim a 24-21 win. Although it’s a speculative wager, we are expecting things to be close between the two teams.

Miami (OH) vs Buffalo Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

The latest Moneyline odds are -104 that Buffalo win, while Miami-Ohio have been chalked up at -116. The probability of the home team winning this college game is 51% according to the sportsbooks.

The spread is calculated to be 1.5, while total points comes in at 39.5. Having a bet on the Totals is one of the most popular football wagers. If you’re wanting to back Over 39.5, the odds are -105.

If you’re getting ready to place a college football bet, head over to one of the top betting apps and explore the wide variety of game lines and team props. Take your time to spot the most appealing opportunities.

Moneyline

Miami (OH)

-116

Buffalo

-104

Point Spread

Miami (OH) -1.5

-105

Buffalo +1.5

-115

Total Points

Under 39.5

-115

Over 39.5

-105

Receiving Yards

Nik McMillan (Buffalo)

Over 81.5

-114

Under 81.5

-114

Kam Perry (Miami (OH))

Over 48.5

-114

Under 48.5

-114

Victor Snow (Buffalo)

Over 48.5

-114

Under 48.5

-114

Cole Weaver (Miami (OH))

Over 40.5

-114

Under 40.5

-114

Jasaiah Gathings (Buffalo)

Over 30.5

-114

Under 30.5

-114

Rushing Yards

Jordan Brunson (Miami (OH))

Over 59.5

-114

Under 59.5

-114

Buffalo Have Six Wins From Past Ten Home Game

Buffalo have gone 6-4 across their last 10 home games, putting up 32.50 points on average and giving up 22.20.

Miami-Ohio own a 6-4 mark in their past 10 games on the road, posting 23.80 points per contest while yielding 20.10.

Buffalo defeated Miami-Ohio 24-20 the last time they played at University of Buffalo Stadium.

Last 10 Games		W-L	P	PF	PA	O39.5	U39.5
Buffalo Home Stats		6-4	54.70	32.50	22.20	7	3
Miami (OH) Away Stats		6-4	43.90	23.80	20.10	7	3

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O39.5 = Games Over 39.5 Points
• U39.5 = Games Under 39.5 Points

Latest regular season and playoff games stats.

Miami-Ohio Stats

Buffalo Bulls Stats

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 home games

Point Spread

• -1.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -1.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• +1.5 Betting Line: Have covered the spread in 5 of the last 10 games
• +1.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 45.00 pts in the previous 10 games
• Game Totals on the Road: An average of 43.90 pts in the previous 10 games on the road
• Over 39.5: Covered in 5 of the previous 10 games
• Over 39.5 on the Road: Covered in 7 of the previous 10 games on the road
• Team Totals: Have scored an average of 23.10 pts and allowed 21.90 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 23.80 pts and allowed 20.10 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 45.60 pts in the previous 10 games
• Game Totals at Home: An average of 54.70 pts in the previous 10 home games
• Over 39.5: Covered in 6 of the previous 10 games
• Over 39.5 at Home: Covered in 7 of the previous 10 home games
• Team Totals: Have scored an average of 24.20 pts and allowed 21.40 pts in the last 10 games
• Team Totals at Home: Have scored an average of 32.50 pts and allowed 22.20 pts in the last 10 home games

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