Minnesota vs Northwestern Prediction, Picks & Odds | 22 Nov 2025
College Football Betting Preview: Minnesota vs Northwestern
Minnesota square off against Northwestern at Wrigley Field, with kickoff scheduled for 12:00 on Saturday, November 22.
Northwestern should be taken against the spread at -3.5 with our prediction being for the favorites to achieve a comfortable margin of victory in their meeting with Minnesota. Back them at the odds of -114 that are available.
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Minnesota Golden Gophers have now lost four straight road games. In their previous game, Oregon Ducks won 42-13 at Autzen Stadium.
Northwestern Wildcats have lost in their last three outings. At Wrigley Field, they were recently turned over 24-22 by Michigan Wolverines.
Head-to-Head Statistics
The last matchup between Northwestern and Minnesota saw the former win. It was a 37-34 (OT) scoreline at Ryan Field. Minnesota have won three of the past 4 games that these teams have played.
Quarterbacks
Drake Lindsey
Preston Stone
Minnesota vs Northwestern Prediction & Picks
This expert Minnesota vs Northwestern betting breakdown features our match prediction, a correct score tip, player prop suggestions and a carefully constructed bet builder to guide your wagers.
Game Prediction
Our pick is that Northwestern are going to cover the -3.5 on the spread. You can get -114 that there’s a bigger margin of victory in this college football matchup.
We only publish our CFB predictions once we’ve got a clear and confident read on team news and the latest form. We also stay sharp by digging into the most valuable stats to support every pick we make.
Key Minnesota vs Northwestern stats:
Northwestern -3.5 Probability
If you go by the top betting apps, there’s a 53.2% chance that our pick is settled as a winner. However, we have this figure at close to 60% based on our in-depth research. It’s why we think it’s worth placing this college bet.
If you are looking for bigger odds, then you are able to move the line. Choose from a wide range of options and get rewarded if your selection exceeds expectations.
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Player Prop Picks
Drake Lindsey (Minnesota) is priced at -114 to finish with fewer than 188.5 passing yards. It’s reasonable to expect he may fall short, making the QB Passing Yards line appealing.
You can back Caleb Komolafe (Northwestern) at -114 to have less than 69.5 rushing yards. He is likely to fall short of the line, making this Player Rushing Yards bet an appealing option.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
Take a same game parlay that incorporates Northwestern to cover the -3.5 spread along with Over 40.5 points. We’ve also gone for Drake Lindsey (Minnesota) to have Under 188.5 passing yards.
Should you want to back different outcomes for the same game, then a football same game parlay will suit your needs. The betting sites create this personalised wagering tool where you can make different picks and combine the odds together.
Correct Score Prediction
21
-
27
Northwestern
Correct score betting might be tough to predict but there’s a tasty potential return if you get it right. We’ll try the Wildcats to achieve a 27-21 victory at massive odds.
Minnesota vs Northwestern Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
The Northwestern odds have been priced up by the sportsbooks and they are -167 betting favorites to land victory in this college game which means a 63% chance of winning. For those wanting to back Minnesota, you will find +142 about the underdogs.
The current spread is 3.5 and total points is 40.5. Having a bet on the Totals is one of the most popular football wagers. If you fancy Under 40.5, then the odds are -105.
You can find a wide range of team props and game lines for every college football matchup, with the best sportsbooks creating lots of different options. Explore the pre-game and in-game selections before placing your wagers.
Those interested in favorite Caleb Komolafe to score the first touchdown are able to get +320. If the Anytime TD angle makes appeal, then this is -164.
Touchdown
Receiving Yards
Rushing Yards
Passing Yards
An increasing number of bettors are now enjoying micro betting on college football and it’s something which is available on an in-game basis. Wait for the action to start and then wager on something specific to happen.
Latest regular season and playoff games stats.
Minnesota Golden Gophers Stats
Northwestern Wildcats Stats
- 6 wins and 4 defeats in the last 10 games
- 4 wins and 6 defeats in the last 10 games on the road
- +3.5 Betting Line: Have covered the spread in 6 of the last 10 games
- +3.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road
- -3.5 Betting Line: Have covered the spread in 3 of the last 10 games
- -3.5 Betting Line at Home: Have covered the spread in 3 of the last 10 home games
- Game Totals: An average of 46.30 pts in the previous 10 games
- Game Totals on the Road: An average of 42.60 pts in the previous 10 games on the road
- Over 40.5: Covered in 8 of the previous 10 games
- Over 40.5 on the Road: Covered in 7 of the previous 10 games on the road
- Team Totals: Have scored an average of 22.70 pts and allowed 23.60 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 17.00 pts and allowed 25.60 pts in the last 10 games on the road
- Game Totals: An average of 41.50 pts in the previous 10 games
- Game Totals at Home: An average of 43.70 pts in the previous 10 home games
- Over 40.5: Covered in 7 of the previous 10 games
- Over 40.5 at Home: Covered in 6 of the previous 10 home games
- Team Totals: Have scored an average of 21.90 pts and allowed 19.60 pts in the last 10 games
- Team Totals at Home: Have scored an average of 21.80 pts and allowed 21.90 pts in the last 10 home games
| Big Ten | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Indiana
|
13 | 0 | 545 | 141 | 404 | 7-0 | 6-0 | 13W |
Ohio State
|
12 | 1 | 454 | 106 | 348 | 7-1 | 5-0 | 1L |
Oregon
|
11 | 1 | 458 | 178 | 280 | 6-1 | 5-0 | 6W |
Michigan
|
9 | 3 | 331 | 224 | 107 | 5-1 | 4-2 | 1L |
USC
|
9 | 3 | 438 | 269 | 169 | 7-0 | 2-3 | 1W |
Iowa
|
8 | 4 | 347 | 182 | 165 | 5-2 | 3-2 | 2W |
Illinois
|
8 | 4 | 352 | 279 | 73 | 6-1 | 2-3 | 1W |
Washington
|
8 | 4 | 405 | 233 | 172 | 5-2 | 3-2 | 1L |
|
Minnesota
|
7 | 5 | 279 | 281 | -2 | 7-0 | 0-5 | 1W |
Nebraska
|
7 | 5 | 351 | 276 | 75 | 4-3 | 3-2 | 2L |
|
Northwestern
|
6 | 6 | 270 | 251 | 19 | 5-2 | 1-4 | 1L |
Penn State
|
6 | 6 | 381 | 257 | 124 | 4-3 | 2-3 | 3W |
Rutgers
|
5 | 7 | 344 | 382 | -38 | 4-3 | 1-4 | 2L |
Wisconsin
|
4 | 8 | 154 | 259 | -105 | 4-3 | 0-5 | 1L |
Maryland
|
4 | 8 | 282 | 318 | -36 | 3-4 | 1-4 | 8L |
Michigan State
|
4 | 8 | 295 | 359 | -64 | 4-3 | 0-5 | 1W |
UCLA
|
3 | 9 | 218 | 401 | -183 | 2-4 | 1-5 | 5L |
Purdue
|
2 | 10 | 225 | 382 | -157 | 2-5 | 0-5 | 10L |
Belmont
UIC
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