Missouri vs Vanderbilt Prediction, Picks & Odds | 25 Oct 2025

College Football Betting Preview: Missouri vs Vanderbilt

Missouri square off against Vanderbilt in this NCAAF Week 9 matchup at FirstBank Stadium, with kickoff scheduled for 15:30 on Saturday 25 October. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.

Vandy Should Have the Edge

We’re heading to the Moneyline and our betting prediction is for Vanderbilt to win. They have a strong chance of beating Missouri and the -143 makes plenty of appeal.

Putting your money on Vanderbilt? Grab the latest BetMGM promo code and check out our comprehensive review before you place your bet.

5 Wins for Mizzou in Previous 6 H2H Clashes

Missouri Tigers won their previous game 23-17. This was a road victory at Jordan-Hare Stadium against Auburn Tigers.

Vanderbilt Commodores were winners last time out. Their 31-24 victory against LSU Tigers at FirstBank Stadium was their fourth straight home triumph.

Head-to-Head Statistics

Missouri beat Vanderbilt in their last head-to-head matchup. It was a 30-27 (OT) scoreline at Faurot Field. Missouri have won five of the past 6 games that these teams have played.

Quarterbacks

Beau Pribula

209.5 Passing Yards

Over -114

Under -114

Diego Pavia

217.5 Passing Yards

Over -114

Under -114

Missouri vs Vanderbilt Prediction & Picks

Get the edge with our best Missouri vs Vanderbilt tips: a key match prediction, correct score recommendation, top player prop bets and a ready-made bet builder.

Game Prediction

We’re keeping our pick nice and simple by heading to the Moneyline. Take the -143 that Vanderbilt are able to secure a victory in this college football matchup.

The college football picks at Sportsgambler.com are always guided by the latest team news, injury updates and overall form. Once we've reviewed that, we dive into the most relevant stats to confidently recommend every pick.

Key Missouri vs Vanderbilt stats:

• Vanderbilt have won 5 consecutive games at home.
• Vanderbilt have won 6 of their last 7 games this season.
• Vanderbilt have won 7 of their last 10 games.
• Missouri have lost 10 of their last 18 games on the road.

Vandy Moneyline Probability

Looking at the latest betting odds, our pick has a 58.8% chance of winning. Taking all factors into consideration, our analysts think there’s a stronger chance of success and have a probability interval between 65-70%. It’s the reason why we are recommending this college bet.

If you’re wanting bigger odds about Vandy, then there are a number of viable alternatives including the Spread, Double Result and the Result & Total lines.

Ready to wager? Discover top betting deals and find the most valuable sportsbook promo codes in our trusted bonus guide filled with perks.

Best Bet

Vanderbilt Moneyline @ -143 Bet Now

BetMGM Promo Up To $1500 in Bonus Bets Get Bonus T&C apply. Gamble responsibly 18+

Gamble responsibly 18+. All odds are correct at time of publishing and are subject to change. To use the Bookmaker Live Streaming services you will need to be logged in and have a funded account or to have placed a bet in the last 24 hours. Geo-restrictions apply.

Player Prop Picks

Top Pick: Beau Pribula Under 209.5 Passing Yards -114

Beau Pribula (Missouri) is available at -114 to end with fewer than 209.5 passing yards. There’s a strong case for choosing him to fall short of the required line in the QB Passing Yards market.

Latest Beau Pribula Player Prop Odds

Passing Yards

Over 209.5

-114

Under 209.5

-114

Rushing Yards

Over 28.5

-114

Under 28.5

-114

---

Marquis Johnson Under 32.5 Receiving Yards -114

Marquis Johnson (Missouri) can be backed at -114 to have less than 32.5 receiving yards. It’s reasonable to expect he may fall short, making the Player Receiving Yards line appealing.

Latest Marquis Johnson Player Prop Odds

Receiving Yards

Over 32.5

-114

Under 32.5

-114

Correct Score Prediction

Missouri 27 - 31 Vanderbilt

There are massive odds available when it comes to the Commodores claiming a 31-27 victory. A close battle is anticipated between two evenly-matched teams.

Missouri vs Vanderbilt Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Vandy Favorites to Win According to the Books

Sportsbooks’ favorites Vanderbilt are regarded as likeliest victors for this college game and the -143 about them triumphing means a 59% chance based on their current Moneyline betting odds. Missouri are the underdogs at +120 and they’re regarded as least likely to win.

2.5 is where the spread lies, with total points being 53.5 right now. There is no denying the popularity of wagering on the Totals. If you want to back Over 53.5, it’s -110.

If you’re betting on college football, we recommend heading to the top betting apps and scanning through the many team props and game lines. There’s a chance to wager pre-game and in-game.

Moneyline

Missouri

+120

Vanderbilt

-143

Point Spread

Missouri +2.5

-105

Vanderbilt -2.5

-115

Total Points

Under 53.5

-110

Over 53.5

-110

Player Odds

Receiving Yards

Kevin Coleman Jr. (Missouri)

Over 53.5

-114

Under 53.5

-114

Eli Stowers (Vanderbilt)

Over 45.5

-114

Under 45.5

-114

Junior Sherrill (Vanderbilt)

Over 34.5

-114

Under 34.5

-114

Marquis Johnson (Missouri)

Over 32.5

-114

Under 32.5

-114

Brett Norfleet (Missouri)

Over 25.5

-114

Under 25.5

-114

Rushing Yards

Ahmad Hardy (Missouri)

Over 86.5

-114

Under 86.5

-114

Diego Pavia (Vanderbilt)

Over 53.5

-114

Under 53.5

-114

Sedrick Alexander (Vanderbilt)

Over 40.5

-114

Under 40.5

-114

Beau Pribula (Missouri)

Over 28.5

-114

Under 28.5

-114

Passing Yards

Diego Pavia (Vanderbilt)

Over 217.5

-114

Under 217.5

-114

Beau Pribula (Missouri)

Over 209.5

-114

Under 209.5

-114

Vanderbilt Racking Up the Home Wins

Vanderbilt have strung together four consecutive wins at FirstBank Stadium. They have a 7-3 record in their last 10 home games, posting 37.40 points per contest while yielding 22.30.

Missouri have six wins and four losses in the last 10 games away from home, putting up 26.80 points per contest and giving up 21.70.

Missouri defeated Vanderbilt 38-21 when the teams last met at FirstBank Stadium. The last 3 head-to-heads at FirstBank Stadium show Missouri with two wins, while Vanderbilt have one to their name.

Last 10 Games		W-L	P	PF	PA	O53.5	U53.5
Vanderbilt Home Stats		7-3	59.70	37.40	22.30	6	4
Missouri Away Stats		6-4	48.50	26.80	21.70	4	6

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O53.5 = Games Over 53.5 Points
• U53.5 = Games Under 53.5 Points

Last 5 & H2H

Latest regular season and playoff games stats.

Missouri Tigers Stats

Vanderbilt Commodores Stats

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +2.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +2.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• -2.5 Betting Line: Have covered the spread in 7 of the last 10 games
• -2.5 Betting Line at Home: Have covered the spread in 7 of the last 10 home games

Total Points

• Game Totals: An average of 54.90 pts in the previous 10 games
• Game Totals on the Road: An average of 48.50 pts in the previous 10 games on the road
• Over 53.5: Covered in 4 of the previous 10 games
• Over 53.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 36.70 pts and allowed 18.20 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 26.80 pts and allowed 21.70 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 59.20 pts in the previous 10 games
• Game Totals at Home: An average of 60.40 pts in the previous 10 home games
• Over 53.5: Covered in 6 of the previous 10 games
• Over 53.5 at Home: Covered in 6 of the previous 10 home games
• Team Totals: Have scored an average of 36.50 pts and allowed 22.70 pts in the last 10 games
• Team Totals at Home: Have scored an average of 35.40 pts and allowed 25.00 pts in the last 10 home games

NCAAF Standings Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Southeastern	W	L	PF	PA	N. Pts	Home	Away	Strk
Texas A&M	7	0	253	164	89	5-0	2-0	7W
Alabama	6	1	246	124	122	4-0	2-1	6W
Georgia	6	1	236	137	99	4-1	2-0	3W
Missouri	6	1	273	117	156	5-1	1-0	1W
Oklahoma	6	1	201	66	135	4-0	2-1	1W
Ole Miss	6	1	262	158	104	5-0	1-1	1L
Vanderbilt	6	1	290	140	150	4-0	2-1	1W
LSU	5	2	179	102	77	4-0	1-2	1L
Tennessee	5	2	309	213	96	4-1	1-1	1L
Texas	5	2	187	79	108	4-0	1-2	2W
Mississippi State	4	3	223	142	81	3-1	1-2	3L
Auburn	3	4	165	125	40	2-2	1-2	4L
Florida	3	4	157	140	17	3-1	0-3	1W
South Carolina	3	4	141	140	1	3-2	0-2	2L
Kentucky	2	4	135	155	-20	2-2	0-2	3L
Arkansas	2	5	260	229	31	2-2	0-3	5L