Missouri vs Vanderbilt Prediction, Picks & Odds | 25 Oct 2025
College Football Betting Preview: Missouri vs Vanderbilt
Missouri square off against Vanderbilt in this NCAAF Week 9 matchup at FirstBank Stadium, with kickoff scheduled for 15:30 on Saturday, October 25. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.
We’re heading to the Moneyline and our betting prediction is for Vanderbilt to win. They have a strong chance of beating Missouri and the -143 makes plenty of appeal.
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Missouri Tigers won their previous game 23-17. This was a road victory at Jordan-Hare Stadium against Auburn Tigers.
Vanderbilt Commodores were winners last time out. Their 31-24 victory against LSU Tigers at FirstBank Stadium was their fourth straight home triumph.
Head-to-Head Statistics
Missouri beat Vanderbilt in their last head-to-head matchup. It was a 30-27 (OT) scoreline at Faurot Field. Missouri have won five of the past 6 games that these teams have played.
Quarterbacks
Beau Pribula
Diego Pavia
Missouri vs Vanderbilt Prediction & Picks
Get the edge with our best Missouri vs Vanderbilt tips: a key match prediction, correct score recommendation, top player prop bets and a ready-made bet builder.
Game Prediction
We’re keeping our pick nice and simple by heading to the Moneyline. Take the -143 that Vanderbilt are able to secure a victory in this college football matchup.
The college football picks at Sportsgambler.com are always guided by the latest team news, injury updates and overall form. Once we've reviewed that, we dive into the most relevant stats to confidently recommend every pick.
Key Missouri vs Vanderbilt stats:
Vandy Moneyline Probability
Looking at the latest betting odds, our pick has a 58.8% chance of winning. Taking all factors into consideration, our analysts think there’s a stronger chance of success and have a probability interval between 65-70%. It’s the reason why we are recommending this college bet.
If you’re wanting bigger odds about Vandy, then there are a number of viable alternatives including the Spread, Double Result and the Result & Total lines.
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Player Prop Picks
Beau Pribula (Missouri) is available at -114 to end with fewer than 209.5 passing yards. There’s a strong case for choosing him to fall short of the required line in the QB Passing Yards market.
Marquis Johnson (Missouri) can be backed at -114 to have less than 32.5 receiving yards. It’s reasonable to expect he may fall short, making the Player Receiving Yards line appealing.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
Get in the game with this same game parlay. Our selections are Vanderbilt on the moneyline, Over 53.5 on the total and Beau Pribula (Missouri) to go Under 209.5 passing yards.
The same game parlay option is fantastic for football bettors wanting a personalised multi-leg wager on the same game. It’s especially good if you have a strong opinion on the likely outcomes and the odds for each selection are combined.
Correct Score Prediction
27
-
31
Vanderbilt
There are massive odds available when it comes to the Commodores claiming a 31-27 victory. A close battle is anticipated between two evenly-matched teams.
Missouri vs Vanderbilt Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
Sportsbooks’ favorites Vanderbilt are regarded as likeliest victors for this college game and the -154 about them triumphing means a 61% chance based on their current Moneyline betting odds. Missouri are the underdogs at +130 and they’re regarded as least likely to win.
3.5 is where the spread lies, with total points being 52.5 right now. There is no denying the popularity of wagering on the Totals. If you want to back Over 52.5, it’s -104.
If you’re betting on college football, we recommend heading to the top betting apps and scanning through the many team props and game lines. There’s a chance to wager pre-game and in-game.
Receiving Yards
Rushing Yards
Passing Yards
Vanderbilt Racking Up the Home Wins
Vanderbilt have strung together four consecutive wins at FirstBank Stadium. They have a 7-3 record in their last 10 home games, posting 37.40 points per contest while yielding 22.30.
Missouri have six wins and four losses in the last 10 games away from home, putting up 26.80 points per contest and giving up 21.70.
Missouri defeated Vanderbilt 38-21 when the teams last met at FirstBank Stadium. The last 3 head-to-heads at FirstBank Stadium show Missouri with two wins, while Vanderbilt have one to their name.
| Last 10 Games | W-L | P | PF | PA | O53.5 | U53.5 | |
|---|---|---|---|---|---|---|---|
 Vanderbilt Home Stats |
7-3 | 59.70 | 37.40 | 22.30 | 6 | 4 | |
 Missouri Away Stats |
6-4 | 48.50 | 26.80 | 21.70 | 4 | 6 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O53.5 = Games Over 53.5 Points
- U53.5 = Games Under 53.5 Points
Latest regular season and playoff games stats.
Missouri Tigers Stats
Vanderbilt Commodores Stats
- 9 wins and 1 defeat in the last 10 games
- 6 wins and 4 defeats in the last 10 games on the road
- +2.5 Betting Line: Have covered the spread in 9 of the last 10 games
- +2.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road
- -2.5 Betting Line: Have covered the spread in 7 of the last 10 games
- -2.5 Betting Line at Home: Have covered the spread in 7 of the last 10 home games
- Game Totals: An average of 54.90 pts in the previous 10 games
- Game Totals on the Road: An average of 48.50 pts in the previous 10 games on the road
- Over 53.5: Covered in 4 of the previous 10 games
- Over 53.5 on the Road: Covered in 4 of the previous 10 games on the road
- Team Totals: Have scored an average of 36.70 pts and allowed 18.20 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 26.80 pts and allowed 21.70 pts in the last 10 games on the road
- Game Totals: An average of 59.20 pts in the previous 10 games
- Game Totals at Home: An average of 60.40 pts in the previous 10 home games
- Over 53.5: Covered in 6 of the previous 10 games
- Over 53.5 at Home: Covered in 6 of the previous 10 home games
- Team Totals: Have scored an average of 36.50 pts and allowed 22.70 pts in the last 10 games
- Team Totals at Home: Have scored an average of 35.40 pts and allowed 25.00 pts in the last 10 home games
| Southeastern | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Georgia
|
12 | 1 | 415 | 207 | 208 | 6-1 | 6-0 | 9W |
Ole Miss
|
11 | 1 | 447 | 241 | 206 | 8-0 | 3-1 | 5W |
Texas A&M
|
11 | 1 | 436 | 263 | 173 | 7-0 | 4-1 | 1L |
Oklahoma
|
10 | 2 | 317 | 167 | 150 | 6-1 | 4-1 | 4W |
|
Vanderbilt
|
10 | 2 | 473 | 263 | 210 | 7-0 | 3-2 | 3W |
Alabama
|
10 | 3 | 406 | 226 | 180 | 6-2 | 4-1 | 1L |
Texas
|
9 | 3 | 355 | 237 | 118 | 7-0 | 2-3 | 2W |
|
Missouri
|
8 | 4 | 386 | 233 | 153 | 6-2 | 2-2 | 1W |
Tennessee
|
8 | 4 | 489 | 345 | 144 | 5-3 | 3-1 | 1L |
LSU
|
7 | 5 | 262 | 220 | 42 | 6-1 | 1-4 | 1L |
Kentucky
|
5 | 7 | 276 | 317 | -41 | 4-3 | 1-4 | 2L |
Auburn
|
5 | 7 | 321 | 248 | 73 | 3-4 | 2-3 | 1L |
Mississippi State
|
5 | 7 | 366 | 350 | 16 | 3-4 | 2-3 | 3L |
Florida
|
4 | 8 | 259 | 288 | -29 | 4-3 | 0-5 | 1W |
South Carolina
|
4 | 8 | 272 | 265 | 7 | 4-4 | 0-4 | 1L |
Arkansas
|
2 | 10 | 395 | 406 | -11 | 2-5 | 0-5 | 10L |
Belmont
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