Notre Dame vs Pittsburgh Prediction, Picks & Odds | 15 Nov 2025
College Football Betting Preview: Notre Dame vs Pitt Panthers
Notre Dame face Pitt Panthers at Acrisure Stadium, with kickoff scheduled for 12:00 on Saturday, November 15.
The Overs is sticking out like a sore thumb considering the line for Pitt Panthers and Notre Dame is set at 53.5. We’re expecting a bigger total and -114 is available.
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Notre Dame Fighting Irish claimed a home victory in their previous game. A 49-10 triumph against Navy Midshipmen at Notre Dame Stadium made it seven straight wins.
Pittsburgh Panthers got a fifth straight win in their last game. It was a 35-20 road triumph at Stanford Stadium when meeting Stanford Cardinal.
Head-to-Head Statistics
Notre Dame beat Pitt when the teams last met. It was a 58-7 scoreline at Notre Dame Stadium.
Quarterbacks
CJ Carr
Mason Heintschel
Notre Dame vs Pittsburgh Prediction & Picks
Be fully equipped for Notre Dame vs Pittsburgh with our betting guide, offering a key match prediction, a correct score recommendation, top player prop picks and a bet builder tailored for value.
Game Prediction
You can get -114 that there are Over 53.5 points and there’s plenty of juice in those odds. The two teams should be able to keep the score ticking for our college football pick to win.
Our CFB predictions are always well-researched, starting with a combination of the latest team news and current form. Once we’ve got a solid read on the matchup, we layer in the key data to back it up.
Key Notre Dame vs Pittsburgh stats:
Over 53.5 Probability
According to the latest betting odds, our pick has a 53.2% chance of winning. However, our cappers research has found that the actual probability is closer to 60%. The bet can be recommended for this precise reason.
The sportsbooks give you the option to get bigger odds for your Overs pick by combining this selection on the Result & Total lines. Predict a team to win as part of the deal.
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Player Prop Picks
You can back Mason Heintschel (Pitt) at -114 to record more than 263.5 passing yards. We feel confident that he’ll cover the QB Passing Yards line, which looks generous.
Malachi Fields (Notre Dame) is priced at -114 to rack up over 46.5 receiving yards. We feel confident that he’ll cover the Player Receiving Yards line, which looks generous.
Same Game Parlay Picks
Our same game parlay pick is Over 53.5, Pitt +12.5 on the spread and Mason Heintschel (Pitt) to have Over 263.5 passing yards.
Many betting sites now allow you to place a same game parlay on each individual football game. It means that you can create a personalised wager at bigger odds, with there generally being no limit as to the number of picks.
Correct Score Prediction
35
-
28
Pittsburgh
Should you wish to go for a speculative bet, try the Irish to triumph 35-28 on the correct score lines. This should be a fun wager which could potentially yield a huge return.
Notre Dame vs Pittsburgh Odds
The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.
At betting odds of -455 with the sportsbooks, Notre Dame are regarded as 82% likely to win this college game. Pittsburgh are the underdogs at +350 and they’re regarded as least likely to win.
12.5 is where the spread lies, with total points being 54.5 right now. The beauty of the Totals is that you only have to choose from one of two options. There’s an opportunity to bet Over 54.5 at -110.
If you’re getting ready to place a college football bet, head over to one of the top betting apps and explore the wide variety of game lines and team props. Take your time to spot the most appealing opportunities.
Favorite Jeremiyah Love is now available at +290 to be the First Touchdown Scorer. You will find similar odds apply when it comes to him scoring the last TD.
Touchdown
Receiving Yards
Rushing Yards
Passing Yards
Micro betting is an exciting way to wager on college football. There are a huge range of live lines and it’s a simple case of predicting what is going to happen next. Field Goal Outcome, Next Drive Result and Next Play Result are often among the options.
Pitt Own Seven Wins From Last Ten at Home
Pitt own a 7-3 mark in their past 10 home games, averaging 40.40 points on offense and surrendering 19.40 on defense.
Notre Dame own a 9-1 mark in their past 10 games on the road, posting 37.50 points per contest while yielding 16.60.
The last time these teams met at Acrisure Stadium, Notre Dame came out on top 45-3 against Pitt.
| Last 10 Games | W-L | P | PF | PA | O53.5 | U53.5 | |
|---|---|---|---|---|---|---|---|
 Pittsburgh Home Stats |
7-3 | 59.80 | 40.40 | 19.40 | 7 | 3 | |
 Notre Dame Away Stats |
9-1 | 54.10 | 37.50 | 16.60 | 4 | 6 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O53.5 = Games Over 53.5 Points
- U53.5 = Games Under 53.5 Points
Latest regular season and playoff games stats.
Notre Dame Fighting Irish Stats
Pittsburgh Stats
- 7 wins and 3 defeats in the last 10 games
- 9 wins and 1 defeat in the last 10 games on the road
- -12.5 Betting Line: Have covered the spread in 6 of the last 10 games
- -12.5 Betting Line on the Road: Have covered the spread in 7 of the last 10 games on the road
- +12.5 Betting Line: Have covered the spread in the last 10 games
- +12.5 Betting Line at Home: Have covered the spread in the last 10 home games
- Game Totals: An average of 57.40 pts in the previous 10 games
- Game Totals on the Road: An average of 54.10 pts in the previous 10 games on the road
- Over 53.5: Covered in 6 of the previous 10 games
- Over 53.5 on the Road: Covered in 4 of the previous 10 games on the road
- Team Totals: Have scored an average of 37.10 pts and allowed 20.30 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 37.50 pts and allowed 16.60 pts in the last 10 games on the road
- Game Totals: An average of 64.70 pts in the previous 10 games
- Game Totals at Home: An average of 59.80 pts in the previous 10 home games
- Over 53.5: Covered in 9 of the previous 10 games
- Over 53.5 at Home: Covered in 7 of the previous 10 home games
- Team Totals: Have scored an average of 40.30 pts and allowed 24.40 pts in the last 10 games
- Team Totals at Home: Have scored an average of 40.40 pts and allowed 19.40 pts in the last 10 home games
| Atlantic Coast | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Virginia
|
10 | 2 | 398 | 240 | 158 | 6-1 | 4-1 | 2W |
Miami
|
10 | 2 | 409 | 166 | 243 | 7-1 | 3-1 | 4W |
Georgia Tech
|
9 | 3 | 397 | 300 | 97 | 5-2 | 4-1 | 2L |
|
Pittsburgh
|
8 | 4 | 421 | 299 | 122 | 4-3 | 4-1 | 1L |
SMU
|
8 | 4 | 395 | 248 | 147 | 5-1 | 3-3 | 1L |
Louisville
|
8 | 4 | 362 | 253 | 109 | 5-3 | 3-1 | 1W |
Wake Forest
|
8 | 4 | 322 | 258 | 64 | 5-2 | 3-2 | 1L |
Duke
|
7 | 5 | 415 | 353 | 62 | 3-3 | 4-2 | 2W |
NC State
|
7 | 5 | 362 | 346 | 16 | 6-1 | 1-4 | 2W |
Clemson
|
7 | 5 | 344 | 245 | 99 | 3-4 | 4-1 | 4W |
California
|
7 | 5 | 298 | 318 | -20 | 4-2 | 3-3 | 1W |
Florida State
|
5 | 7 | 396 | 264 | 132 | 5-2 | 0-5 | 2L |
Stanford
|
4 | 8 | 226 | 350 | -124 | 4-2 | 0-6 | 1L |
North Carolina
|
4 | 8 | 231 | 294 | -63 | 2-4 | 2-4 | 3L |
Virginia Tech
|
3 | 9 | 257 | 362 | -105 | 2-5 | 1-4 | 4L |
Syracuse
|
3 | 9 | 242 | 419 | -177 | 2-4 | 1-5 | 8L |
Boston College
|
2 | 10 | 305 | 393 | -88 | 1-6 | 1-4 | 1W |
| Independents I-A | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
|
Notre Dame
|
10 | 2 | 504 | 211 | 293 | 6-1 | 4-1 | 10W |
UConn
|
9 | 3 | 443 | 310 | 133 | 6-0 | 3-3 | 4W |
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