Ohio vs Ohio State Prediction, Picks & Odds | 13 Sep 2025
College Football Betting Preview: Ohio vs Ohio State
Ohio battle Ohio State in this NCAAF matchup at Ohio Stadium, with kickoff scheduled for 19:00 on Saturday 13 September. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.
Under 50.5 is Our Best Pick
Under 50.5 points looks like an attractive total wager. Ohio State and Ohio might not be able to reach this combined amount and we can profit with this pick at -110.
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Both Teams Won Last Time Out
Ohio Bobcats previous game saw them claim a 17-10 home win over West Virginia Mountaineers at Peden Stadium.
Ohio State Buckeyes made it back-to-back wins in their last game. Landing a 70-0 home victory against Grambling State Tigers at Ohio Stadium.
Quarterbacks


Ohio vs Ohio State Prediction & Picks
Prepare for Ohio vs Ohio State with our expert betting guide featuring a trusted match prediction, likely scoreline, key player props and a well-crafted bet builder.
Game Prediction
The -110 about Under 50.5 points makes lots of appeal and represents value in our eyes. We’re not sure that the teams can combine to reach that number for this college football matchup.
Our CFB predictions are always well-researched, starting with a combination of the latest team news and current form. Once we’ve got a solid read on the matchup, we layer in the key data to back it up.
Key Ohio vs Ohio State stats:
Under 50.5 Probability
Looking at the latest betting odds, our pick has a 52.4% chance of winning. Based on our in-depth research, we calculate the actual probability to be closer to 60%. That means we’re regarding it as a value bet.
Bettors looking for more juice from their Unders bet can check out the Result & Total lines. Here you simply combine points with the team that will win.
Maximize your next wager by exploring our top betting offers filled with welcome bonuses, promos, and the best free bets.
Best Bet
Under 50.5 Points @ -110
Player Prop Picks
You can place a bet on Julian Sayin (Ohio State) at -114 to finish with fewer than 272.5 passing yards. We're confident he’ll fall short of the QB Passing Yards line, so we're backing the Under.

Jeremiah Smith (Ohio) is priced at -114 to record fewer than 95.5 receiving yards. There’s a strong case for opting for him to fall short of the required total in the Player Receiving Yards market.

Same Game Parlay Picks
Our same game parlay pick is Under 50.5, Ohio +30.5 on the spread and Julian Sayin (Ohio State) to have Under 272.5 passing yards.
Should you want to back different outcomes for the same game, then a football same game parlay will suit your needs. The betting sites create this personalised wagering tool where you can make different picks and combine the odds together.
Correct Score Prediction
Ohio vs Ohio State Odds
The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.
Books Make Ohio State Big Favorites
The favorites are 99% likely to win according to the sportsbooks’ latest Money Line odds, with Ohio State priced at -10000 to triumph in this college game. If you’re looking for an alternative angle, Ohio are trading at +2400.
The spread currently stands at 30.5 and the total points line is 50.5. A Total wager is always available and can often provide value selections. If you want to bet Under 50.5, there are odds of -110.
The top sportsbooks cover every college football matchup with a great mix of game lines and team props. Whether you prefer to bet before kickoff or during the action, make sure to explore all available options.




Player Odds
Receiving Yards




Rushing Yards





Passing Yards




Ohio State Riding a Home Hot Streak
Ohio State have strung together three in a row at Ohio Stadium. They own a 9-1 mark in their past 10 home games, putting up 38.00 points per contest and giving up 9.00.
Ohio have a 6-4 record in their last 10 games on the road, averaging 26.40 points on offense and surrendering 21.90 on defense.
Last 10 Games | W-L | P | PF | PA | O50.5 | U50.5 | |
---|---|---|---|---|---|---|---|
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9-1 | 47.00 | 38.00 | 9.00 | 5 | 5 | |
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6-4 | 48.30 | 26.40 | 21.90 | 4 | 6 |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O50.5 = Games Over 50.5 Points
- U50.5 = Games Under 50.5 Points
Last 5 & H2H
Latest regular season and playoff games stats.


- 8 wins and 2 defeats in the last 10 games
- 6 wins and 4 defeats in the last 10 games on the road
- +30.5 Betting Line: Have covered the spread in the last 10 games
- +30.5 Betting Line on the Road: Have covered the spread in 9 of the last 10 games on the road
- -30.5 Betting Line: Have covered the spread in 2 of the last 10 games
- -30.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games
- Game Totals: An average of 48.30 pts in the previous 10 games
- Game Totals on the Road: An average of 48.30 pts in the previous 10 games on the road
- Over 50.5: Covered in 4 of the previous 10 games
- Over 50.5 on the Road: Covered in 4 of the previous 10 games on the road
- Team Totals: Have scored an average of 32.50 pts and allowed 15.80 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 26.40 pts and allowed 21.90 pts in the last 10 games on the road
- Game Totals: An average of 47.00 pts in the previous 10 games
- Game Totals at Home: An average of 47.00 pts in the previous 10 home games
- Over 50.5: Covered in 5 of the previous 10 games
- Over 50.5 at Home: Covered in 5 of the previous 10 home games
- Team Totals: Have scored an average of 35.30 pts and allowed 11.70 pts in the last 10 games
- Team Totals at Home: Have scored an average of 38.00 pts and allowed 9.00 pts in the last 10 home games
NCAAF Standings Select Season
Big Ten | W | L | PF | PA | N. Pts | Home | Away | Strk |
---|---|---|---|---|---|---|---|---|
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2 | 0 | 97 | 22 | 75 | 1-0 | 1-0 | 2W |
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2 | 0 | 80 | 11 | 69 | 2-0 | 0-0 | 2W |
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2 | 0 | 59 | 10 | 49 | 2-0 | 0-0 | 2W |
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2 | 0 | 108 | 31 | 77 | 2-0 | 0-0 | 2W |
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2 | 0 | 132 | 33 | 99 | 2-0 | 0-0 | 2W |
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2 | 0 | 79 | 48 | 31 | 2-0 | 0-0 | 2W |
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2 | 0 | 83 | 23 | 60 | 2-0 | 0-0 | 2W |
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2 | 0 | 65 | 17 | 48 | 2-0 | 0-0 | 2W |
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2 | 0 | 128 | 16 | 112 | 2-0 | 0-0 | 2W |
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2 | 0 | 84 | 7 | 77 | 2-0 | 0-0 | 2W |
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2 | 0 | 88 | 17 | 71 | 1-0 | 1-0 | 2W |
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2 | 0 | 89 | 10 | 79 | 2-0 | 0-0 | 2W |
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2 | 0 | 65 | 46 | 19 | 2-0 | 0-0 | 2W |
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2 | 0 | 59 | 16 | 43 | 2-0 | 0-0 | 2W |
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1 | 1 | 47 | 23 | 24 | 1-0 | 0-1 | 1L |
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1 | 1 | 47 | 41 | 6 | 1-0 | 0-1 | 1L |
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1 | 1 | 45 | 30 | 15 | 1-0 | 0-1 | 1W |
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0 | 2 | 33 | 73 | -40 | 0-1 | 0-1 | 2L |
Mid-American | W | L | PF | PA | N. Pts | Home | Away | Strk |
---|---|---|---|---|---|---|---|---|
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1 | 1 | 46 | 41 | 5 | 1-0 | 0-1 | 1L |
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1 | 1 | 55 | 29 | 26 | 1-0 | 0-1 | 1W |
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1 | 1 | 33 | 59 | -26 | 0-0 | 1-1 | 1L |
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1 | 1 | 35 | 79 | -44 | 1-0 | 0-1 | 1L |
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1 | 1 | 28 | 37 | -9 | 1-0 | 0-1 | 1L |
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1 | 1 | 48 | 44 | 4 | 1-0 | 0-1 | 1W |
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1 | 1 | 61 | 45 | 16 | 1-0 | 0-1 | 1W |
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0 | 2 | 0 | 78 | -78 | 0-1 | 0-1 | 2L |
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0 | 2 | 3 | 73 | -70 | 0-0 | 0-2 | 2L |
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0 | 2 | 50 | 80 | -30 | 0-1 | 0-1 | 2L |
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0 | 2 | 36 | 69 | -33 | 0-2 | 0-0 | 2L |
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0 | 2 | 17 | 62 | -45 | 0-0 | 0-2 | 2L |
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0 | 2 | 36 | 56 | -20 | 0-1 | 0-1 | 2L |

































































