Oregon vs Northwestern Prediction, Picks & Odds | 13 Sep 2025

College Football Betting Preview: Oregon vs Northwestern

Oregon meet Northwestern in this NCAAF matchup at Northwestern Medicine Field at Martin Stadium, with kickoff scheduled for 12:00 on Saturday 13 September. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.

Oregon Could Make it a One-Sided Affair

We’re predicting that Oregon will beat Northwestern by a significant margin. With this in mind, let’s go for the favorites at -27.5 on the spread which is currently on offer at -110.

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Both Teams Victorious in Last Game

Oregon Ducks have won their previous two games. The latest was a 69-3 home triumph at Autzen Stadium against Oklahoma State Cowboys.

Northwestern Wildcats were winners last time out. It was a 42-7 home victory against Western Illinois Leathernecks at Northwestern Medicine Field at Martin Stadium.

Quarterbacks

Dante Moore

235.5 Passing Yards

Over -114

Under -114

Preston Stone

160.5 Passing Yards

Over -114

Under -114

Oregon vs Northwestern Prediction & Picks

Our Oregon vs Northwestern betting tips provide expert coverage of all major angles, including our main match prediction, top player prop picks, correct score recommendation and best bet builder insights.

Game Prediction

Our best pick is that Oregon will be superior in this college football matchup and that’s why we’re backing the favorites on the spread at -27.5. Take the -110 that they are able to cover the line.

We use the latest team news and injury updates to help shape the best possible CFB predictions. You’ll also notice we take a stats-led approach by factoring in the key numbers that truly make a difference.

Key Oregon vs Northwestern stats:

• The -27.5 line has been covered by Oregon in 3 of their last 5 games.
• The -27.5 line has been covered by Oregon in 2 consecutive games.

Oregon -27.5 Probability

Based on the odds from the top sportsbooks, our pick has a 52.4% chance of winning. Taking all factors into consideration, our experts think there’s a stronger chance of success and estimate the probability to be closer to 60%. This is why we can recommend this college wager.

As a betting option, you can choose to buy or sell points when it comes to your selection. Buy if you want a safer wager and sell to get more juice from the line.

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Best Bet

Oregon -27.5 @ -110 Bet Now

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Player Prop Picks

Top Pick: Dante Moore Over 235.5 Passing Yards -114

You can place a bet on Dante Moore (Oregon) at -114 to rack up over 235.5 passing yards. The line for him on the Overs is highly appealing, with QB Passing Yards bettors able to get plenty of juice.

Latest Dante Moore Player Prop Odds

Passing Yards

Over 235.5

-114

Under 235.5

-114

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Malik Benson Over 47.5 Receiving Yards -114

The odds for Malik Benson (Northwestern) to surpass 47.5 receiving yards stand at -114. We’re happy to take him to cover the Player Receiving Yards line and bettors can place this wager with confidence.

Latest Malik Benson Player Prop Odds

Receiving Yards

Over 47.5

-114

Under 47.5

-114

Correct Score Prediction

Oregon 38 - 3 Northwestern

For those looking to get more bang for their buck, consider a correct score wager on the Ducks. Backing them to win 38-3 means you can land a potential monster return.

Oregon vs Northwestern Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Books Running Scared of Oregon Win

At betting odds of -10000 with the sportsbooks, Oregon are regarded as 99% likely to win this college game. If you’re looking for an alternative angle, Northwestern are trading at +2400.

The spread currently stands at 27.5 and the total points line is 48.5. A Total wager is always available and can often provide value selections. If you’re going for Under 48.5, this outcome can be backed at -110.

If you’re planning to place a college football wager, visit the best betting apps and check out the huge selection of available team props and game lines. Find the odds and betting lines which are the most attractive.

Moneyline

Oregon

-10000

Northwestern

+2400

Point Spread

Oregon -27.5

-118

Northwestern +27.5

-104

Total Points

Under 48.5

-110

Over 48.5

-110

Player Odds

Receiving Yards

Griffin Wilde (Northwestern)

Over 60.5

-114

Under 60.5

-114

Malik Benson (Oregon)

Over 47.5

-114

Under 47.5

-114

Dakorien Moore (Oregon)

Over 43.5

-114

Under 43.5

-114

Kenyon Sadiq (Oregon)

Over 32.5

-114

Under 32.5

-114

Passing Yards

Dante Moore (Oregon)

Over 235.5

-114

Under 235.5

-114

Preston Stone (Northwestern)

Over 160.5

-114

Under 160.5

-114

Last 5 & H2H

Latest regular season and playoff games stats.

Oregon Ducks Stats

Northwestern Wildcats Stats

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 8 wins and 2 defeats in the last 10 games on the road

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 home games

Point Spread

• -27.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -27.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• +27.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +27.5 Betting Line at Home: Have covered the spread in the last 10 home games

Total Points

• Game Totals: An average of 58.10 pts in the previous 10 games
• Game Totals on the Road: An average of 51.40 pts in the previous 10 games on the road
• Over 48.5: Covered in 7 of the previous 10 games
• Over 48.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 40.90 pts and allowed 17.20 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 36.20 pts and allowed 15.20 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 47.30 pts in the previous 10 games
• Game Totals at Home: An average of 40.60 pts in the previous 10 home games
• Over 48.5: Covered in 5 of the previous 10 games
• Over 48.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 19.00 pts and allowed 28.30 pts in the last 10 games
• Team Totals at Home: Have scored an average of 20.50 pts and allowed 20.10 pts in the last 10 home games

NCAAF Standings Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big Ten	W	L	PF	PA	N. Pts	Home	Away	Strk
Illinois	2	0	97	22	75	1-0	1-0	2W
Penn State	2	0	80	11	69	2-0	0-0	2W
Wisconsin	2	0	59	10	49	2-0	0-0	2W
Washington	2	0	108	31	77	2-0	0-0	2W
USC	2	0	132	33	99	2-0	0-0	2W
Rutgers	2	0	79	48	31	2-0	0-0	2W
Indiana	2	0	83	23	60	2-0	0-0	2W
Purdue	2	0	65	17	48	2-0	0-0	2W
Oregon	2	0	128	16	112	2-0	0-0	2W
Ohio State	2	0	84	7	77	2-0	0-0	2W
Nebraska	2	0	88	17	71	1-0	1-0	2W
Minnesota	2	0	89	10	79	2-0	0-0	2W
Michigan State	2	0	65	46	19	2-0	0-0	2W
Maryland	2	0	59	16	43	2-0	0-0	2W
Iowa	1	1	47	23	24	1-0	0-1	1L
Michigan	1	1	47	41	6	1-0	0-1	1L
Northwestern	1	1	45	30	15	1-0	0-1	1W
UCLA	0	2	33	73	-40	0-1	0-1	2L