Oregon State vs Oregon Prediction, Picks & Odds | 20 Sep 2025

College Football Betting Preview: Oregon State vs Oregon

Oregon State lock horns with Oregon in this NCAAF Week 4 matchup at Autzen Stadium, with kickoff scheduled for 15:00 on Saturday 20 September. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.

We’re Expecting Oregon State to Cover the Spread

Oregon State can give a good account of themselves against Oregon. They can prevent a big loss and there is -118 available that the underdogs cover the +35.5 spread.

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Teams’ Previous H2H Saw 49-14 Oregon Victory

Oregon State Beavers have suffered a defeat in their previous three games including a recent 45-14 loss. This occurred on the road at Jones AT&T Stadium against Texas Tech Red Raiders.

Oregon Ducks got a third straight win in their last game. It was a 34-14 road triumph at Northwestern Medicine Field at Martin Stadium when meeting Northwestern Wildcats.

Head-to-Head Statistics

Oregon have claimed back-to-back victories over Oregon State. At Autzen Stadium they won 31-7 before winning 49-14 at Reser Stadium. The past 6 clashes between these teams have seen four Oregon wins.

Oregon State vs Oregon Prediction & Picks

Prepare for Oregon State vs Oregon with our expert betting guide featuring a trusted match prediction, a correct score recommendation and a well-crafted bet builder.

Game Prediction

Oregon State have been given a more than generous +35.5 line on the spread. We think they can avoid a big loss in this college football matchup and you can play them at -118.

We only publish our CFB predictions once we’ve got a clear and confident read on team news and the latest form. We also stay sharp by digging into the most valuable stats to support every pick we make.

Key Oregon State vs Oregon stats:

• The +35.5 line has been covered by Oregon State in 7 consecutive games.
• The +35.5 line has been covered by Oregon State in 19 of their last 20 games.
• The +35.5 line has been covered by Oregon State in 9 of their last 10 games.
• The -35.5 line hasn’t been covered by Oregon in 17 of their last 20 games.
• The -35.5 line hasn’t been covered by Oregon in 8 of their last 10 games.
• The -35.5 line hasn’t been covered by Oregon in 6 consecutive games against Oregon State.

Oregon State +35.5 Probability

If you go by the top betting apps, there’s a 54.1% chance that our pick is settled as a winner. Our experts think there’s a stronger chance of success and calculate the probability to be closer to 60%. It’s why we think it’s worth placing this college bet.

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Best Bet

Oregon State +35.5 @ -118 Bet Now

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Correct Score Prediction

Oregon State 17 - 49 Oregon

We’re going for the Ducks to claim a 49-17 victory and the good news is that there are huge odds for this outcome. A small stake can return a potentially large amount.

Oregon State vs Oregon Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Oregon Expected to Win By Huge Margin

The sportsbooks make this college game uncompetitive, with Oregon expected to comfortably win. Therefore, the Moneyline might not be available and it’s better to instead play the spread to assess the various options.

35.5 is the spread and 56.5 is the total points line. Football bettors regularly enjoy the opportunity to wager on the Totals. There’s the chance to back Under 56.5 at -110.

College football bettors are spoilt for choice thanks to the huge selection of team props and game lines which are available for every matchup on the coupon. Head to the top sportsbooks and find the best value wagers.

Moneyline

Oregon State

-

Oregon

-

Point Spread

Oregon State +35.5

-118

Oregon -35.5

-104

Total Points

Under 56.5

-110

Over 56.5

-110

Player Props & Micro Betting

If you have a view on Player Interceptions, Passing Attempts or Longest Pass Completion, then the player prop betting could be up your street. It’s a great way of wagering on a player or quarterback to perform well.

For those looking to enjoy a thrilling in-game wager, then college football micro betting could be up your street. You are now able to wager on what will happen on the next snap by staking your money on the Next Play Result.

Oregon Riding a Home Hot Streak

Oregon have ten wins and zero loss in the last 10 games at home, scoring 42.30 points per matchup and conceding 15.90.

Oregon State have taken five consecutive losses away from home. They have gone 2-8 across their last 10 games away from home, averaging 16.20 points scored and 31.00 points allowed.

The most recent Autzen Stadium meeting saw Oregon claim a 31-7 win over Oregon State. Oregon have taken all 3 of the recent head-to-head meetings at Autzen Stadium.

Last 10 Games		W-L	P	PF	PA	O56.5	U56.5
Oregon Home Stats		10-0	58.20	42.30	15.90	6	4
Oregon State Away Stats		2-8	47.20	16.20	31.00	2	8

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O56.5 = Games Over 56.5 Points
• U56.5 = Games Under 56.5 Points

Last 5 & H2H

Latest regular season and playoff games stats.

Oregon State Beavers Stats

Oregon Ducks Stats

Moneyline

• 1 win and 9 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• +35.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +35.5 Betting Line on the Road: Have covered the spread in 9 of the last 10 games on the road

Point Spread

• -35.5 Betting Line: Have covered the spread in 2 of the last 10 games
• -35.5 Betting Line at Home: Have covered the spread in 2 of the last 10 home games

Total Points

• Game Totals: An average of 55.50 pts in the previous 10 games
• Game Totals on the Road: An average of 47.20 pts in the previous 10 games on the road
• Over 56.5: Covered in 5 of the previous 10 games
• Over 56.5 on the Road: Covered in 2 of the previous 10 games on the road
• Team Totals: Have scored an average of 19.70 pts and allowed 35.80 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 16.20 pts and allowed 31.00 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 59.40 pts in the previous 10 games
• Game Totals at Home: An average of 63.70 pts in the previous 10 home games
• Over 56.5: Covered in 6 of the previous 10 games
• Over 56.5 at Home: Covered in 8 of the previous 10 home games
• Team Totals: Have scored an average of 40.80 pts and allowed 18.60 pts in the last 10 games
• Team Totals at Home: Have scored an average of 42.00 pts and allowed 21.70 pts in the last 10 home games

NCAAF Standings Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big Ten	W	L	PF	PA	N. Pts	Home	Away	Strk
Illinois	3	0	135	22	113	2-0	1-0	3W
Penn State	3	0	132	17	115	3-0	0-0	3W
Washington	2	0	108	31	77	2-0	0-0	2W
Indiana	3	0	156	23	133	3-0	0-0	3W
Rutgers	3	0	139	58	81	3-0	0-0	3W
USC	3	0	165	50	115	2-0	1-0	3W
Oregon	3	0	162	30	132	2-0	1-0	3W
Ohio State	3	0	121	16	105	3-0	0-0	3W
Nebraska	3	0	147	24	123	2-0	1-0	3W
Michigan State	3	0	106	70	36	3-0	0-0	3W
Maryland	3	0	103	33	70	3-0	0-0	3W
Iowa	2	1	94	30	64	2-0	0-1	1W
Michigan	2	1	110	44	66	2-0	0-1	1W
Minnesota	2	1	103	37	66	2-0	0-1	1L
Purdue	2	1	82	50	32	2-1	0-0	1L
Wisconsin	2	1	73	48	25	2-0	0-1	1L
Northwestern	1	2	59	64	-5	1-1	0-1	1L
UCLA	0	3	43	108	-65	0-2	0-1	3L

Pacific-12	W	L	PF	PA	N. Pts	Home	Away	Strk
Washington State	2	1	59	82	-23	2-0	0-1	1L
Oregon State	0	3	56	115	-59	0-2	0-1	3L