Penn State vs Michigan State Prediction, Picks & Odds | 15 Nov 2025
College Football Betting Preview: Penn State vs Michigan State
Penn State battle Michigan State at Spartan Stadium, with kickoff scheduled for 15:30 on Saturday, November 15.
The best betting angle could be wagering on the totals when Michigan State clash with Penn State. Our prediction is for Over 48.5 points to be scored at odds of -114.
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Penn State Nittany Lions have lost in their previous six outings. In a recent home game at Beaver Stadium, they were turned over 27-24 by Indiana Hoosiers.
Michigan State Spartans have been defeated in their last six games. On the road, they recently suffered a 23-20 (OT) loss against Minnesota Golden Gophers at Huntington Bank Stadium.
Head-to-Head Statistics
Penn State have beaten Michigan State in the last two matchups. A 35-16 victory at Beaver Stadium was followed by a 42-0 win at Spartan Stadium. Penn State have won four of the previous 5 H2H meetings.
Penn State vs Michigan State Prediction & Picks
Our Penn State vs Michigan State preview includes expert betting advice on all fronts — from a match prediction and correct score guidance to player prop selections and a bet builder tailored for value.
Game Prediction
The two teams are capable of exceeding the set points total line which leads us to predict Over 48.5 as a value wager at -114 for this college football matchup.
Getting the lowdown on injuries and analyzing the form guide are key steps before making CFB predictions. We also put strong emphasis on stats, where a data-led approach often leads to smarter picks.
Key Penn State vs Michigan State stats:
Over 48.5 Probability
The top betting apps make it a 53.2% chance that our pick is settled as a winner. However, our cappers have this figure closer to 60% based on their in-depth research. This is why we can recommend this college wager.
If you are wanting bigger odds for your Total bet, then it’s possible to move the line and get more juice. You can choose to wager Over when it comes to different levels.
Thinking of placing a bet? Make sure to check our guide first — it’s full of the latest offers and welcome bonuses worth claiming.
Player Prop Picks
You can place a bet on Ethan Grunkemeyer (Penn State) at -114 to surpass 189.5 passing yards. We're confident in him covering the QB Passing Yards line and hitting our Over bet.
Nick Marsh (Penn State) is available at -114 to surpass 56.5 receiving yards. We’re happy to take him to cover the Player Receiving Yards line and bettors can place this wager with confidence.
Same Game Parlay Picks
We’ve loaded up a same game parlay with the combined picks of Over 48.5, Penn State -7.5 and Ethan Grunkemeyer (Penn State) to have Over 189.5 passing yards.
Many betting sites now allow you to place a same game parlay on each individual football game. It means that you can create a personalised wager at bigger odds, with there generally being no limit as to the number of picks.
Correct Score Prediction
34
-
21
Michigan State
There’s lots of entertainment when it comes to a correct score wager. A play on the Lions to achieve a 34-21 win should give bettors a good run for their money.
Penn State vs Michigan State Odds
The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.
Penn State are -270 favorites and that means a 73% chance of winning this college game according to the Moneyline betting odds with the sportsbooks. For those wanting to back Michigan State, you will find +220 about the underdogs.
The spread currently stands at 7.5 and the total points line is 49.5. A wager on the Totals allows football bettors to use the latest data to good effect. If you’re going for Over 49.5, then the odds are -105.
College football bettors are spoilt for choice thanks to the huge selection of team props and game lines which are available for every matchup on the coupon. Head to the top sportsbooks and find the best value wagers.
You will find Kaytron Allen at +360 to be First Touchdown Scorer which makes him the favorite. There’s the opportunity to get -185 that he scores a TD at anytime.
Touchdown
Receiving Yards
Rushing Yards
It’s good to consider all wagering options when it comes to college football and micro betting can be an exciting way to get involved in the action. When everything goes in-game, consider whether a player will make or miss a field goal.
Michigan State Have Won Five of Their Last Ten Home Games
Michigan State own a 5-5 mark in their past 10 home games, posting 22.60 points per contest while yielding 30.20.
Penn State have been beaten in three straight games away from home. They have a 6-4 record in their last 10 road games, scoring 31.30 points per contest and conceding 25.40.
Penn State defeated Michigan State 42-0 the last time they played at Spartan Stadium. Across 3 head-to-heads at Spartan Stadium, Penn State have registered two wins and Michigan State one.
| Last 10 Games | W-L | P | PF | PA | O48.5 | U48.5 | |
|---|---|---|---|---|---|---|---|
 Michigan State Home Stats |
5-5 | 52.80 | 22.60 | 30.20 | 7 | 3 | |
 Penn State Away Stats |
6-4 | 56.70 | 31.30 | 25.40 | 7 | 3 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O48.5 = Games Over 48.5 Points
- U48.5 = Games Under 48.5 Points
Latest regular season and playoff games stats.
Penn State Nittany Lions Stats
Michigan State Spartans Stats
- 3 wins and 7 defeats in the last 10 games
- 6 wins and 4 defeats in the last 10 games on the road
- -7.5 Betting Line: Have covered the spread in 3 of the last 10 games
- -7.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road
- +7.5 Betting Line: Have covered the spread in 4 of the last 10 games
- +7.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games
- Game Totals: An average of 52.80 pts in the previous 10 games
- Game Totals on the Road: An average of 56.70 pts in the previous 10 games on the road
- Over 48.5: Covered in 8 of the previous 10 games
- Over 48.5 on the Road: Covered in 7 of the previous 10 games on the road
- Team Totals: Have scored an average of 30.00 pts and allowed 22.80 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 31.30 pts and allowed 25.40 pts in the last 10 games on the road
- Game Totals: An average of 56.80 pts in the previous 10 games
- Game Totals at Home: An average of 52.80 pts in the previous 10 home games
- Over 48.5: Covered in 8 of the previous 10 games
- Over 48.5 at Home: Covered in 7 of the previous 10 home games
- Team Totals: Have scored an average of 24.40 pts and allowed 32.40 pts in the last 10 games
- Team Totals at Home: Have scored an average of 22.60 pts and allowed 30.20 pts in the last 10 home games
| Big Ten | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Indiana
|
12 | 0 | 532 | 131 | 401 | 7-0 | 5-0 | 12W |
Ohio State
|
12 | 0 | 444 | 93 | 351 | 7-0 | 5-0 | 12W |
Oregon
|
11 | 1 | 458 | 178 | 280 | 6-1 | 5-0 | 6W |
Michigan
|
9 | 3 | 331 | 224 | 107 | 5-1 | 4-2 | 1L |
USC
|
9 | 3 | 438 | 269 | 169 | 7-0 | 2-3 | 1W |
Iowa
|
8 | 4 | 347 | 182 | 165 | 5-2 | 3-2 | 2W |
Illinois
|
8 | 4 | 352 | 279 | 73 | 6-1 | 2-3 | 1W |
Washington
|
8 | 4 | 405 | 233 | 172 | 5-2 | 3-2 | 1L |
Minnesota
|
7 | 5 | 279 | 281 | -2 | 7-0 | 0-5 | 1W |
Nebraska
|
7 | 5 | 351 | 276 | 75 | 4-3 | 3-2 | 2L |
Northwestern
|
6 | 6 | 270 | 251 | 19 | 5-2 | 1-4 | 1L |
|
Penn State
|
6 | 6 | 381 | 257 | 124 | 4-3 | 2-3 | 3W |
Rutgers
|
5 | 7 | 344 | 382 | -38 | 4-3 | 1-4 | 2L |
Wisconsin
|
4 | 8 | 154 | 259 | -105 | 4-3 | 0-5 | 1L |
Maryland
|
4 | 8 | 282 | 318 | -36 | 3-4 | 1-4 | 8L |
|
Michigan State
|
4 | 8 | 295 | 359 | -64 | 4-3 | 0-5 | 1W |
UCLA
|
3 | 9 | 218 | 401 | -183 | 2-4 | 1-5 | 5L |
Purdue
|
2 | 10 | 225 | 382 | -157 | 2-5 | 0-5 | 10L |
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