Purdue vs Michigan Prediction, Picks & Odds | 01 Nov 2025

College Football Betting Preview: Purdue vs Michigan

Purdue battle Michigan in this NCAAF matchup at Michigan Stadium, with kickoff scheduled for 19:00 on Saturday 1 November. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.

Michigan Against The Spread?

We’re predicting that Michigan will be superior to Purdue and that’s why we’re backing them at -21.5 on the spread. Take the -106 that the big favorites are able to cover this line.

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Michigan 41-13 Winners in Most Recent H2H

Purdue Boilermakers have suffered six straight defeats, recently being beaten at home by Rutgers Scarlet Knights 27-24 at Ross-Ade Stadium.

Michigan Wolverines have now achieved four straight home wins. In their last game, they won on the road at Spartan Stadium when beating Michigan State Spartans 31-20.

Head-to-Head Statistics

Michigan won the most recent matchup between these teams. A 41-13 victory was registered against Purdue at Michigan Stadium.

Purdue vs Michigan Prediction & Picks

Our Purdue vs Michigan betting preview covers everything you need, including a key match prediction, correct score insight, top player prop bets and a value-packed bet builder recommendation.

Game Prediction

We have decided to go for Michigan against the spread in order to get the best value. They should be able to cover the -21.5 line at odds of -106 for this college football showdown.

We use the latest team news and injury updates to help shape the best possible CFB predictions. You’ll also notice we take a stats-led approach by factoring in the key numbers that truly make a difference.

Key Purdue vs Michigan stats:

• The +21.5 line hasn’t been covered by Purdue in 4 of their last 10 games on the road.

Michigan -21.5 Probability

The top betting apps make it a 51.5% chance that our pick is settled as a winner. In our opinion, there’s actually a probability of success between 55-60%. This is why we regard this as a value bet.

If you’re hunting for tastier odds, then a Bet Builder could be the way to go. Combine Michigan against the spread with other picks until you’re happy with the overall price.

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Best Bet

Michigan -21.5 @ -106 Bet Now

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Player Prop Picks

Top Pick: Bryce Underwood Over 184.5 Passing Yards -114

Bryce Underwood (Michigan) is available at -114 to accumulate over 184.5 passing yards. We can place a QB Passing Yards bet with confidence, as we expect him to cover the line.

Latest Bryce Underwood Player Prop Odds

Passing Yards

Over 184.5

-114

Under 184.5

-114

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Devin Mockobee Over 41.5 Rushing Yards -114

Devin Mockobee (Michigan) can be backed at -114 to rack up over 41.5 rushing yards. There’s an opportunity to place a Player Rushing Yards bet, with him capable of covering an appealing line.

Latest Devin Mockobee Player Prop Odds

Rushing Yards

Over 41.5

-114

Under 41.5

-114

Correct Score Prediction

Purdue 9 - 35 Michigan

There’s the chance to land massive odds when it comes to a the Wolverines correct score win. We’ll try a 35-9 victory in their favor and this should be in the right ball park.

Purdue vs Michigan Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Books Have Michigan as Heavy Favorites

Michigan have short betting odds and they’re overwhelming -2000 favorites for this college game. This means the sportsbooks give them a 95% chance of winning. Purdue are trading at bigger odds than their opponents and they can be backed at +1100.

The spread is 21.5 and the total points line is currently 49.5. Football bettors regularly enjoy the opportunity to wager on the Totals. Those that want to back Under 49.5 can find odds of -115 available.

You can find a wide range of team props and game lines for every college football matchup, with the best sportsbooks creating lots of different options. Explore the pre-game and in-game selections before placing your wagers.

Moneyline

Purdue

+1100

Michigan

-2000

Point Spread

Purdue +21.5

-114

Michigan -21.5

-106

Total Points

Under 49.5

-115

Over 49.5

-105

Player Odds

Receiving Yards

Andrew Marsh (Michigan)

Over 54.5

-114

Under 54.5

-114

Michael Jackson III (Purdue)

Over 35.5

-114

Under 35.5

-114

Donaven McCulley (Michigan)

Over 34.5

-114

Under 34.5

-114

Nitro Tuggle (Purdue)

Over 28.5

-114

Under 28.5

-114

Rushing Yards

Devin Mockobee (Purdue)

Over 41.5

-114

Under 41.5

-114

Can Michigan Keep Rolling at Home?

Michigan have reeled off five straight wins at Michigan Stadium. They own a 9-1 mark in their past 10 home games, posting 31.80 points per contest while yielding 16.40.

Purdue have suffered ten defeats in a row away from home. They are 0-10 in their last 10 games away from home, putting up 15.80 points per contest and giving up 40.00.

Michigan beat Purdue 41-13 when they last met at Michigan Stadium.

Last 10 Games		W-L	P	PF	PA	O49.5	U49.5
Michigan Home Stats		9-1	48.20	31.80	16.40	6	4
Purdue Away Stats		0-10	55.80	15.80	40.00	5	5

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O49.5 = Games Over 49.5 Points
• U49.5 = Games Under 49.5 Points

Last 5 & H2H

Latest regular season and playoff games stats.

Purdue Boilermakers Stats

Michigan Wolverines Stats

Moneyline

• 2 wins and 8 defeats in the last 10 games
• 0 wins and 10 defeats in the last 10 games on the road

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• +21.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +21.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• -21.5 Betting Line: Have covered the spread in 1 of the last 10 games
• -21.5 Betting Line at Home: Have covered the spread in 2 of the last 10 home games

Total Points

• Game Totals: An average of 51.20 pts in the previous 10 games
• Game Totals on the Road: An average of 55.80 pts in the previous 10 games on the road
• Over 49.5: Covered in 6 of the previous 10 games
• Over 49.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 20.00 pts and allowed 31.20 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 15.80 pts and allowed 40.00 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 42.60 pts in the previous 10 games
• Game Totals at Home: An average of 46.80 pts in the previous 10 home games
• Over 49.5: Covered in 4 of the previous 10 games
• Over 49.5 at Home: Covered in 6 of the previous 10 home games
• Team Totals: Have scored an average of 26.40 pts and allowed 16.20 pts in the last 10 games
• Team Totals at Home: Have scored an average of 30.90 pts and allowed 15.90 pts in the last 10 home games

NCAAF Standings Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big Ten	W	L	PF	PA	N. Pts	Home	Away	Strk
Indiana	8	0	363	87	276	6-0	2-0	8W
Ohio State	7	0	255	41	214	4-0	3-0	7W
Oregon	7	1	330	108	222	4-1	3-0	2W
Iowa	6	2	250	105	145	4-1	2-1	3W
Michigan	6	2	232	139	93	4-0	2-2	2W
Nebraska	6	2	280	157	123	4-1	2-1	1W
Washington	6	2	284	167	117	4-1	2-1	1W
USC	5	2	297	162	135	4-0	1-2	1L
Northwestern	5	3	180	134	46	4-1	1-2	1L
Minnesota	5	3	191	174	17	5-0	0-3	1L
Illinois	5	3	263	220	43	3-1	2-2	2L
Maryland	4	3	198	121	77	3-2	1-1	3L
Rutgers	4	4	251	245	6	3-2	1-2	1W
Penn State	3	4	238	136	102	3-2	0-2	4L
Michigan State	3	5	210	260	-50	3-2	0-3	5L
UCLA	3	5	163	248	-85	2-2	1-3	1L
Purdue	2	6	183	222	-39	2-3	0-3	6L
Wisconsin	2	6	100	191	-91	2-3	0-3	6L