South Florida vs Florida Prediction, Picks & Odds | 06 Sep 2025

College Football Betting Preview: South Florida vs Florida

South Florida square off against Florida in this NCAAF Week 2 matchup at Ben Hill Griffin Stadium, with kickoff scheduled for 16:15 on Saturday 6 September. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.

USF Look Value for This Matchup

South Florida can give a good account of themselves against Florida. They can prevent a big loss and there is -106 available that the underdogs cover the +17.5 spread.

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Florida Beat USF When Teams Last Met

South Florida won their previous game which was at home. It was a 34-7 triumph at Raymond James Stadium against Boise State Broncos.

Florida Gators won their last game which was at home. It was a 55-0 triumph at Ben Hill Griffin Stadium against LIU Sharks.

Head-to-Head Statistics

Florida had the edge in the most recent matchup between these teams. At Ben Hill Griffin Stadium, they recorded a 31-28 win over South Florida.

Quarterbacks

Byrum Brown

185.5 Passing Yards

Over -114

Under -114

DJ Lagway

248.5 Passing Yards

Over -114

Under -114

South Florida vs Florida Prediction & Picks

Tackle South Florida vs Florida with all the betting insight you need, including our match prediction, scoreline forecast, key player prop selections and a hand-picked bet builder.

Game Prediction

Let’s back South Florida at +17.5 to outrun their odds on the spread. They are a good shout at -106 to stay relatively close to the big favorites in this college football matchup.

We closely track recent form and look for patterns that may impact the outcome. The same goes for injuries to key players. When combined with the most relevant stats, this gives us a strong foundation for accurate CFB picks.

Key South Florida vs Florida stats:

• The +17.5 line has been covered by South Florida in 5 consecutive games.
• The +17.5 line has been covered by South Florida in 7 of their last 10 games.
• The +17.5 line has been covered by South Florida in 14 of their last 20 games.
• The -17.5 line hasn’t been covered by Florida in 15 of their last 20 games.
• The -17.5 line hasn’t been covered by Florida in 6 of their last 10 games.

USF +17.5 Probability

The best sportsbooks make it a 51.5% chance that our pick is settled as a winner. Taking all factors into consideration, our experts think there’s a stronger chance of success and have a probability interval between 55-60%. It’s the reason why we are recommending this college bet.

If you want to land a big potential return from a small stake, then a Bet Builder could be a way to go. Bet on USF to cover the line in a combination with other selections.

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Best Bet

South Florida +17.5 @ -106 Bet Now

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Player Prop Picks

Top Pick: Byrum Brown Over 185.5 Passing Yards -114

Byrum Brown (South Florida) is available at -114 to accumulate over 185.5 passing yards. We feel confident that he’ll cover the QB Passing Yards line, which looks generous.

Latest Byrum Brown Player Prop Odds

Passing Yards

Over 185.5

-114

Under 185.5

-114

Rushing Yards

Over 42.5

-114

Under 42.5

-114

Correct Score Prediction

South Florida 23 - 38 Florida

A 38-23 win for the Gators is clearly a risky bet although this could be an exciting correct score option where there’s the chance to enjoy a massive potential return.

South Florida vs Florida Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Florida Win on the Cards According to the Books

Florida are strong -1000 favorites to win this college game according to the Moneyline betting odds. The sportsbooks give them a 91% chance of claiming victory. If you’re looking for an alternative angle, South Florida are trading at +640.

There is a spread of 17.5 and total points has a line of 56.5. There are many ways to wager on football including the Totals. Those expecting a low total can back Under 56.5 at -110.

If you're wagering on college football, it's a good idea to visit the top betting apps and browse the extensive selection of team props and game lines. You'll find great opportunities to place bets both pre-game and in-game.

Moneyline

USF

+640

Florida

-1000

Point Spread

USF +17.5

-106

Florida -17.5

-114

Total Points

Under 56.5

-110

Over 56.5

-110

Player Odds

Receiving Yards

Eugene Wilson III (Florida)

Over 53.5

-114

Under 53.5

-114

Keshaun Singleton (USF)

Over 45.5

-114

Under 45.5

-114

Rushing Yards

Jadan Baugh (Florida)

Over 80.5

-114

Under 80.5

-114

Byrum Brown (USF)

Over 42.5

-114

Under 42.5

-114

Passing Yards

DJ Lagway (Florida)

Over 248.5

-114

Under 248.5

-114

Byrum Brown (USF)

Over 185.5

-114

Under 185.5

-114

Florida Rolling at Home

Florida have won six straight at Ben Hill Griffin Stadium. They have a 7-3 record in their last 10 home games, posting 30.80 points per contest while yielding 17.90.

South Florida own a 5-5 mark in their past 10 games on the road, putting up 36.30 points on average and giving up 33.80.

Florida defeated South Florida 31-28 when the teams last met at Ben Hill Griffin Stadium.

Last 10 Games		W-L	P	PF	PA	O56.5	U56.5
Florida Home Stats		7-3	48.70	30.80	17.90	2	8
South Florida Away Stats		5-5	70.10	36.30	33.80	8	2

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O56.5 = Games Over 56.5 Points
• U56.5 = Games Under 56.5 Points

Last 5 & H2H

Latest regular season and playoff games stats.

South Florida Stats

Florida Gators Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +17.5 Betting Line: Have covered the spread in 7 of the last 10 games
• +17.5 Betting Line on the Road: Have covered the spread in 7 of the last 10 games on the road

Point Spread

• -17.5 Betting Line: Have covered the spread in 4 of the last 10 games
• -17.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games

Total Points

• Game Totals: An average of 59.90 pts in the previous 10 games
• Game Totals on the Road: An average of 70.10 pts in the previous 10 games on the road
• Over 56.5: Covered in 6 of the previous 10 games
• Over 56.5 on the Road: Covered in 8 of the previous 10 games on the road
• Team Totals: Have scored an average of 32.40 pts and allowed 27.50 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 36.30 pts and allowed 33.80 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 48.70 pts in the previous 10 games
• Game Totals at Home: An average of 48.70 pts in the previous 10 home games
• Over 56.5: Covered in 2 of the previous 10 games
• Over 56.5 at Home: Covered in 2 of the previous 10 home games
• Team Totals: Have scored an average of 29.60 pts and allowed 19.10 pts in the last 10 games
• Team Totals at Home: Have scored an average of 30.80 pts and allowed 17.90 pts in the last 10 home games

NCAAF Standings Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Southeastern	W	L	PF	PA	N. Pts	Home	Away	Strk
Arkansas	1	0	52	7	45	1-0	0-0	1W
Auburn	1	0	38	24	14	0-0	1-0	1W
Florida	1	0	55	0	55	1-0	0-0	1W
Georgia	1	0	45	7	38	1-0	0-0	1W
Kentucky	1	0	24	16	8	1-0	0-0	1W
LSU	1	0	17	10	7	0-0	1-0	1W
Mississippi State	1	0	34	17	17	0-0	1-0	1W
Missouri	1	0	61	6	55	1-0	0-0	1W
Oklahoma	1	0	35	3	32	1-0	0-0	1W
Ole Miss	1	0	63	7	56	1-0	0-0	1W
South Carolina	1	0	24	11	13	1-0	0-0	1W
Tennessee	1	0	45	26	19	1-0	0-0	1W
Texas A&M	1	0	42	24	18	1-0	0-0	1W
Vanderbilt	1	0	45	3	42	1-0	0-0	1W
Alabama	0	1	17	31	-14	0-0	0-1	1L
Texas	0	1	7	14	-7	0-0	0-1	1L

American Athletic	W	L	PF	PA	N. Pts	Home	Away	Strk
Memphis	1	0	45	10	35	1-0	0-0	1W
Navy	1	0	52	7	45	1-0	0-0	1W
North Texas	1	0	51	0	51	1-0	0-0	1W
Rice	1	0	14	12	2	0-0	1-0	1W
South Florida	1	0	34	7	27	1-0	0-0	1W
Temple	1	0	42	10	32	0-0	1-0	1W
Tulane	1	0	23	3	20	1-0	0-0	1W
Tulsa	1	0	35	7	28	1-0	0-0	1W
UAB	1	0	52	42	10	1-0	0-0	1W
Army	0	1	27	30	-3	0-1	0-0	1L
Charlotte	0	1	11	34	-23	0-1	0-0	1L
East Carolina	0	1	17	24	-7	0-0	0-1	1L
Florida Atlantic	0	1	7	39	-32	0-0	0-1	1L
UTSA	0	1	24	42	-18	0-0	0-1	1L