Wake Forest vs Duke Prediction, Picks & Odds | 29 Nov 2025
College Football Betting Preview: Wake Forest vs Duke
Wake Forest battle Duke at Wallace Wade Stadium, with kickoff scheduled for 15:30 on Saturday, November 29.
Wake Forest should be able to come out on top against Duke. The value bet is to back them on the Moneyline where a juicy -100 can be landed.
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Wake Forest beat Delaware Blue Hens in their previous game, making it three straight victories. It was a 52-14 home win at Allegacy Federal Credit Union Stadium.
Duke Blue Devils have suffered two consecutive home losses. Their last game was a 32-25 road triumph at Kenan Stadium when meeting North Carolina Tar Heels.
Head-to-Head Statistics
Duke won the most recent matchup between these teams. A 23-17 victory was registered against Wake Forest at Allegacy Federal Credit Union Stadium. Duke have triumphed in three of the previous 5 clashes between these teams.
Quarterbacks
Wake Forest vs Duke Prediction & Picks
Our Wake Forest vs Duke preview includes expert betting advice on all fronts — from a match prediction and correct score guidance to player prop selections and a bet builder tailored for value.
Game Prediction
We are really sweet on the road team at the latest odds of -100. They have a great chance of winning this college football matchup and that is our best pick.
To deliver the best possible college football picks, we start by locking in the team news and taking time to review the latest form. There’s also no shortage of data to crunch from the most up-to-date stats available.
Key Wake Forest vs Duke stats:
Wake Forest Moneyline Probability
The top betting apps are suggesting that our pick has a 50% chance of delivering a return. Based on our in-depth research, we calculate the actual probability to be closer to 60%. This college wager can therefore be backed with confidence.
The point spread provides you with the chance to get more juice on your bets. You can move the line for Wake Forest and choose the price to suit you.
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Player Prop Picks
Darian Mensah (Duke) is priced at -114 to finish with fewer than 265.5 passing yards. The line looks too high and we’re confident he’ll fall short of the QB Passing Yards total.
Cooper Barkate (Wake Forest) is available at -114 to have less than 62.5 receiving yards. We’re confident he’ll fall short of the Player Receiving Yards line, as the total looks too high.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
The same game parlay pick is Wake Forest on the moneyline, Under 53.5 on the total and Darian Mensah (Duke) to have Under 265.5 passing yards.
A same game parlay is an awesome way of cheering on different outcomes within the same football game. You can predict a number of outcomes and get bigger odds than a single wager. The odds can combine to great effect.
Correct Score Prediction
Wake Forest vs Duke Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
You can choose Duke at -122 or alternatively Wake Forest who have betting odds of +104. The probability of the home team winning this college game is 55% according to the sportsbooks.
The spread currently stands at 2.5 and the total points line is 53.5. The Totals offers football bettors an alternative way of getting involved. Those who wager Under 53.5 can get -110.
There's a great variety of team props and game lines when it comes to college football wagering and we recommend visiting the top sportsbooks to find the selection that matches your view on the matchup.
Demond Claiborne can be backed to score a touchdown at anytime at -313. He is the favorite to score the first TD at odds of +300.
Touchdown
Receiving Yards
Rushing Yards
Passing Yards
An increasing number of bettors are now enjoying micro betting on college football and it’s something which is available on an in-game basis. Wait for the action to start and then wager on something specific to happen.
Duke Sitting on Six Wins in Previous Ten at Home
Duke have six wins and four losses in the last 10 games at home, scoring 27.20 points per matchup and conceding 26.90.
Wake Forest have six wins and four losses in the last 10 games on the road, scoring 24.50 points per contest and conceding 27.00.
Duke beat Wake Forest 24-21 in their most recent meeting at Wallace Wade Stadium.
| Last 10 Games | W-L | P | PF | PA | O53.5 | U53.5 | |
|---|---|---|---|---|---|---|---|
Duke Home Stats |
6-4 | 54.10 | 27.20 | 26.90 | 5 | 5 | |
Wake Forest Away Stats |
6-4 | 51.50 | 24.50 | 27.00 | 4 | 6 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O53.5 = Games Over 53.5 Points
- U53.5 = Games Under 53.5 Points
Latest regular season and playoff games stats.
Wake Forest Stats
Duke Blue Devils Stats
- 7 wins and 3 defeats in the last 10 games
- 6 wins and 4 defeats in the last 10 games on the road
- +1.5 Betting Line: Have covered the spread in 8 of the last 10 games
- +1.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road
- -1.5 Betting Line: Have covered the spread in 4 of the last 10 games
- -1.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games
- Game Totals: An average of 48.00 pts in the previous 10 games
- Game Totals on the Road: An average of 51.50 pts in the previous 10 games on the road
- Over 53.5: Covered in 3 of the previous 10 games
- Over 53.5 on the Road: Covered in 4 of the previous 10 games on the road
- Team Totals: Have scored an average of 28.00 pts and allowed 20.00 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 24.50 pts and allowed 27.00 pts in the last 10 games on the road
- Game Totals: An average of 62.50 pts in the previous 10 games
- Game Totals at Home: An average of 54.10 pts in the previous 10 home games
- Over 53.5: Covered in 7 of the previous 10 games
- Over 53.5 at Home: Covered in 5 of the previous 10 home games
- Team Totals: Have scored an average of 32.10 pts and allowed 30.40 pts in the last 10 games
- Team Totals at Home: Have scored an average of 27.20 pts and allowed 26.90 pts in the last 10 home games
| Atlantic Coast | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Miami
|
10 | 2 | 409 | 166 | 243 | 7-1 | 3-1 | 4W |
Virginia
|
10 | 3 | 418 | 267 | 151 | 6-2 | 4-1 | 1L |
Georgia Tech
|
9 | 3 | 397 | 300 | 97 | 5-2 | 4-1 | 2L |
Pittsburgh
|
8 | 4 | 421 | 299 | 122 | 4-3 | 4-1 | 1L |
SMU
|
8 | 4 | 395 | 248 | 147 | 5-1 | 3-3 | 1L |
Louisville
|
8 | 4 | 362 | 253 | 109 | 5-3 | 3-1 | 1W |
Wake Forest
|
8 | 4 | 322 | 258 | 64 | 5-2 | 3-2 | 1L |
Duke
|
8 | 5 | 442 | 373 | 69 | 3-3 | 5-2 | 3W |
NC State
|
7 | 5 | 362 | 346 | 16 | 6-1 | 1-4 | 2W |
California
|
7 | 5 | 298 | 318 | -20 | 4-2 | 3-3 | 1W |
Clemson
|
7 | 5 | 344 | 245 | 99 | 3-4 | 4-1 | 4W |
Florida State
|
5 | 7 | 396 | 264 | 132 | 5-2 | 0-5 | 2L |
Stanford
|
4 | 8 | 226 | 350 | -124 | 4-2 | 0-6 | 1L |
North Carolina
|
4 | 8 | 231 | 294 | -63 | 2-4 | 2-4 | 3L |
Virginia Tech
|
3 | 9 | 257 | 362 | -105 | 2-5 | 1-4 | 4L |
Syracuse
|
3 | 9 | 242 | 419 | -177 | 2-4 | 1-5 | 8L |
Boston College
|
2 | 10 | 305 | 393 | -88 | 1-6 | 1-4 | 1W |
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