Wake Forest vs Duke Prediction, Picks & Odds | 29 Nov 2025

College Football Betting Preview: Wake Forest vs Duke

Wake Forest battle Duke at Wallace Wade Stadium, with kickoff scheduled for 15:30 on Saturday, November 29.

Wake Forest should be able to come out on top against Duke. The value bet is to back them on the Moneyline where a juicy -100 can be landed.

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Wake Forest beat Delaware Blue Hens in their previous game, making it three straight victories. It was a 52-14 home win at Allegacy Federal Credit Union Stadium.

Duke Blue Devils have suffered two consecutive home losses. Their last game was a 32-25 road triumph at Kenan Stadium when meeting North Carolina Tar Heels.

Head-to-Head Statistics

Duke won the most recent matchup between these teams. A 23-17 victory was registered against Wake Forest at Allegacy Federal Credit Union Stadium. Duke have triumphed in three of the previous 5 clashes between these teams.

Quarterbacks

Robby Ashford

218.5 Passing Yards

Over -114

Under -114

Darian Mensah

265.5 Passing Yards

Over -114

Under -114

Wake Forest vs Duke Prediction & Picks

Our Wake Forest vs Duke preview includes expert betting advice on all fronts — from a match prediction and correct score guidance to player prop selections and a bet builder tailored for value.

Game Prediction

We are really sweet on the road team at the latest odds of -100. They have a great chance of winning this college football matchup and that is our best pick.

To deliver the best possible college football picks, we start by locking in the team news and taking time to review the latest form. There’s also no shortage of data to crunch from the most up-to-date stats available.

Key Wake Forest vs Duke stats:

• Wake Forest have won 4 of their last 5 games.
• Wake Forest have won 8 of their last 11 games this season.
• Wake Forest have won 3 consecutive games.
• Duke have lost 3 of their last 5 games at home this season.
• Duke have lost their last 2 games at home.

Wake Forest Moneyline Probability

The top betting apps are suggesting that our pick has a 50% chance of delivering a return. Based on our in-depth research, we calculate the actual probability to be closer to 60%. This college wager can therefore be backed with confidence.

The point spread provides you with the chance to get more juice on your bets. You can move the line for Wake Forest and choose the price to suit you.

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Our Game Prediction

Wake Forest Moneyline @ -100 Bet Now

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Player Prop Picks

Top Pick: Darian Mensah Under 265.5 Passing Yards -114

Darian Mensah (Duke) is priced at -114 to finish with fewer than 265.5 passing yards. The line looks too high and we’re confident he’ll fall short of the QB Passing Yards total.

Latest Darian Mensah Player Prop Odds

Touchdown

Anytime

+750

First

+6000

Passing Yards

Over 265.5

-114

Under 265.5

-114

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Cooper Barkate Under 62.5 Receiving Yards -114

Cooper Barkate (Wake Forest) is available at -114 to have less than 62.5 receiving yards. We’re confident he’ll fall short of the Player Receiving Yards line, as the total looks too high.

Latest Cooper Barkate Player Prop Odds

Touchdown

Anytime

-120

First

+700

Receiving Yards

Over 62.5

-114

Under 62.5

-114

Correct Score Prediction

Wake Forest 27 - 17 Duke

A 27-17 win for Wake Forest is clearly a risky bet although this could be an exciting correct score option where there’s the chance to enjoy a massive potential return.

Wake Forest vs Duke Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

You can choose Duke at -118 or alternatively Wake Forest who have betting odds of -100. The probability of the home team winning this college game is 54% according to the sportsbooks.

The spread currently stands at 1.5 and the total points line is 53.5. The Totals offers football bettors an alternative way of getting involved. Those who wager Under 53.5 can get -110.

There's a great variety of team props and game lines when it comes to college football wagering and we recommend visiting the top sportsbooks to find the selection that matches your view on the matchup.

Moneyline

Wake Forest

-100

Duke

-118

Point Spread

Wake Forest +1.5

-110

Duke -1.5

-110

Total Points

Under 53.5

-110

Over 53.5

-110

Demond Claiborne can be backed to score a touchdown at anytime at -345. He is the favorite to score the first TD at odds of +290.

Touchdown

Demond Claiborne (Wake Forest)

First TD

+290

Anytime TD

-345

Nate Sheppard (Duke)

First TD

+600

Anytime TD

-130

Robby Ashford (Wake Forest)

First TD

+650

Anytime TD

-135

Cooper Barkate (Duke)

First TD

+700

Anytime TD

-120

Anderson Castle (Duke)

First TD

+950

Anytime TD

+130

Sahmir Hagans (Duke)

First TD

+950

Anytime TD

+130

Que'Sean Brown (Duke)

First TD

+1100

Anytime TD

+175

Jeremiah Hasley (Duke)

First TD

+1200

Anytime TD

+190

Chris Barnes (Wake Forest)

First TD

+1700

Anytime TD

+260

Carlos Hernandez (Wake Forest)

First TD

+2500

Anytime TD

+460

Ty Clark III (Wake Forest)

First TD

+2700

Anytime TD

+310

Sterling Berkhalter (Wake Forest)

First TD

+2700

Anytime TD

+480

Micah Mays Jr. (Wake Forest)

First TD

+3500

Anytime TD

+650

Eni Falayi (Wake Forest)

First TD

+3500

Anytime TD

+700

Darian Mensah (Duke)

First TD

+6000

Anytime TD

+750

Receiving Yards

Cooper Barkate (Duke)

Over 62.5

-114

Under 62.5

-114

Chris Barnes (Wake Forest)

Over 40.5

-114

Under 40.5

-114

Rushing Yards

Demond Claiborne (Wake Forest)

Over 73.5

-114

Under 73.5

-114

Nate Sheppard (Duke)

Over 68.5

-114

Under 68.5

-114

Robby Ashford (Wake Forest)

Over 53.5

-114

Under 53.5

-114

Anderson Castle (Duke)

Over 31.5

-114

Under 31.5

-114

Passing Yards

Darian Mensah (Duke)

Over 265.5

-114

Under 265.5

-114

Robby Ashford (Wake Forest)

Over 218.5

-114

Under 218.5

-114

Duke Sitting on Six Wins in Previous Ten at Home

Duke have six wins and four losses in the last 10 games at home, scoring 27.20 points per matchup and conceding 26.90.

Wake Forest have six wins and four losses in the last 10 games on the road, scoring 24.50 points per contest and conceding 27.00.

Duke beat Wake Forest 24-21 in their most recent meeting at Wallace Wade Stadium.

Last 10 Games		W-L	P	PF	PA	O53.5	U53.5
Duke Home Stats		6-4	54.10	27.20	26.90	5	5
Wake Forest Away Stats		6-4	51.50	24.50	27.00	4	6

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O53.5 = Games Over 53.5 Points
• U53.5 = Games Under 53.5 Points

Latest regular season and playoff games stats.

Wake Forest Stats

Duke Blue Devils Stats

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 home games

Point Spread

• +1.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +1.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• -1.5 Betting Line: Have covered the spread in 4 of the last 10 games
• -1.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games

Total Points

• Game Totals: An average of 48.00 pts in the previous 10 games
• Game Totals on the Road: An average of 51.50 pts in the previous 10 games on the road
• Over 53.5: Covered in 3 of the previous 10 games
• Over 53.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 28.00 pts and allowed 20.00 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 24.50 pts and allowed 27.00 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 62.50 pts in the previous 10 games
• Game Totals at Home: An average of 54.10 pts in the previous 10 home games
• Over 53.5: Covered in 7 of the previous 10 games
• Over 53.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 32.10 pts and allowed 30.40 pts in the last 10 games
• Team Totals at Home: Have scored an average of 27.20 pts and allowed 26.90 pts in the last 10 home games

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