Cardinals vs 49ers Prediction, Picks & Odds | 06 Oct 2024

Can Cardinals Make it a Close Game?

The best wager could involve backing the Cardinals against the spread. There’s an attractive +7.5 available at -110 that they cover the line against the Niners and that has to be our pick.

7 Victories for Niners in Previous 10 H2H Matchups

Arizona Cardinals have suffered back-to-back defeats, recently being beaten at home by Washington Commanders 42-14 at State Farm Stadium. The Cardinals managed a 296 yard gain, composed of 181 rushing and 115 passing yards. They scored 2 touchdowns. 1 rushing and 1 passing TD.

San Francisco 49ers were winners last time out. Their 30-13 victory against New England Patriots at Levi's Stadium made it back-to-back home wins. The 49ers gained a total of 431 yards, comprising 283 passing and 148 rushing yards. They scored 1 rushing and 1 passing touchdown. 3 TD’s in total.

Head-to-Head Statistics

The Niners beat the Cardinals when the teams last met. It was a 45-29 scoreline at State Farm Stadium. The previous 10 games featuring these teams have resulted in seven Niners victories.

Cardinals vs 49ers Prediction & Picks

We’re sweet on the Cardinals putting up a fight in this NFL matchup and that compels us to back the underdogs against the spread. You can get -110 when it comes to the +7.5 that is available.

Sportsgambler.com boast NFL expertise and that comes from knowing the team news once it’s announced. The latest form will also fuel our predictions and we make sure that the most important stats are on hand.

Key Cardinals vs 49ers stats:

• The +7.5 line has been covered by Cardinals in 4 of their last 5 games.
• The +7.5 line has been covered by Cardinals in 3 of their last 4 games this season.
• The +7.5 line has been covered by Cardinals in 2 consecutive games on the road.
• The -7.5 line hasn’t been covered by 49ers in 7 of their last 10 games.
• The -7.5 line hasn’t been covered by 49ers in 3 of their last 5 games.

Cardinals +7.5 Probability

The sportsbooks imply that our pick has a 52.4% prospect of winning. Our experts think there’s a stronger chance of success and calculate the probability to be closer to 60%. The wager can be recommended for this precise reason.

In the hunt for bigger odds, you might be interested to know that you can move the line. This allows you to shoot for a franchise to perform better than expected by the sportsbooks.

Best Bet

Cardinals +7.5 @ -110 Bet Now

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Correct Score Prediction

Cardinals 27 - 28 49ers

The 49ers are available at huge odds to secure a 28-27 win and they might have the edge. This should be a close battle and there won’t be much between the teams.

Cardinals vs 49ers Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Niners Big Favorites on the Moneyline

The sportsbooks’ betting odds have San Francisco 49ers as -370 favorites for this game, implying that they are 79% likely to win. Arizona Cardinals are the underdogs at +280 and they’re regarded as least likely to win.

There is a spread of 7.5 and total points has a line of 49.5. A Total wager relates to the number of points that will be scored overall. Those that want to back Under 49.5 can find odds of -110 available.

Whether you are betting pre-game or in-game on the National Football League, you can feast on hundreds of team props and game lines. The selections are practically endless and it’s great to have so many options.

Moneyline

Cardinals

+280

49ers

-370

Point Spread

Cardinals +7.5

-103

49ers -7.5

-102

Total Points

Under 49.5

-110

Over 49.5

-105

Player Props & Micro Betting

The gambling sites will have player and quarterback props available for each game. Check out the various betting lines and take a view on whether a player’s Passing Yards or Receiving Yards will be above or below a certain amount.

An increasing number of bettors are now enjoying micro betting on the NFL and it’s something which is available on an in-game basis. Wait for the action to start and then wager on something specific to happen.

Last 5 & H2H

Latest regular season and playoff games stats.

Arizona Cardinals Stats

San Francisco 49ers Stats

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +7.5 Betting Line: Have covered the spread in 6 of the last 10 games
• +7.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• -7.5 Betting Line: Have covered the spread in 3 of the last 10 games
• -7.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games

Total Points

• Game Totals: An average of 51.10 pts in the previous 10 games
• Game Totals on the Road: An average of 42.10 pts in the previous 10 games on the road
• Over 50: Covered in 6 of the previous 10 games
• Over 50 on the Road: Covered in 3 of the previous 10 games on the road
• Team Totals: Have scored an average of 23.40 pts and allowed 27.70 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 17.00 pts and allowed 25.10 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 47.20 pts in the previous 10 games
• Game Totals at Home: An average of 48.20 pts in the previous 10 home games
• Over 50: Covered in 4 of the previous 10 games
• Over 50 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 24.90 pts and allowed 22.30 pts in the last 10 games
• Team Totals at Home: Have scored an average of 27.30 pts and allowed 20.90 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 356.10 Yds. Allowed 362.10 Yds
• Rushing Yards: Gained 159.00 Yds. Allowed 156.80 Yds
• Passing Yards: Gained 197.10 Yds. Allowed 205.30 Yds
• Total Touchdowns: Scored 2.70 TD. Allowed 3.40 TD
• Rushing Touchdowns: Scored 1.00 TD. Allowed 1.20 TD
• Passing Touchdowns: Scored 1.50 TD. Allowed 2.00 TD
• Total 1st Downs: Picked up 20.70. Allowed 21.30
• Total Turnovers: Committed 0.70. Committed by opponents 0.80
• Total Penalties: Committed 4.50. Committed by opponents 4.90
• Penalty Yards: Lost 36.80 Yds. Gained 39.20 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 394.40 Yds. Allowed 323.40 Yds
• Rushing Yards: Gained 137.30 Yds. Allowed 110.60 Yds
• Passing Yards: Gained 257.10 Yds. Allowed 212.80 Yds
• Total Touchdowns: Scored 2.70 TD. Allowed 2.40 TD
• Rushing Touchdowns: Scored 1.30 TD. Allowed 0.80 TD
• Passing Touchdowns: Scored 1.30 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 22.60. Allowed 18.80
• Total Turnovers: Committed 1.40. Committed by opponents 1.50
• Total Penalties: Committed 5.40. Committed by opponents 4.30
• Penalty Yards: Lost 47.10 Yds. Gained 34.80 Yds

Last 10 Games on the Road

• Total Yards: Gained 285.00 Yds. Allowed 345.20 Yds
• Rushing Yards: Gained 121.00 Yds. Allowed 133.50 Yds
• Passing Yards: Gained 164.00 Yds. Allowed 211.70 Yds
• Total Touchdowns: Scored 1.80 TD. Allowed 2.90 TD
• Rushing Touchdowns: Scored 0.60 TD. Allowed 1.10 TD
• Passing Touchdowns: Scored 1.00 TD. Allowed 1.70 TD
• Total 1st Downs: Picked up 18.20. Allowed 20.50
• Total Turnovers: Committed 1.10. Committed by opponents 1.40
• Total Penalties: Committed 5.70. Committed by opponents 5.90
• Penalty Yards: Lost 47.80 Yds. Gained 49.10 Yds

Last 10 Home Games

• Total Yards: Gained 415.80 Yds. Allowed 306.30 Yds
• Rushing Yards: Gained 141.10 Yds. Allowed 99.70 Yds
• Passing Yards: Gained 274.70 Yds. Allowed 206.60 Yds
• Total Touchdowns: Scored 3.20 TD. Allowed 2.50 TD
• Rushing Touchdowns: Scored 1.60 TD. Allowed 0.80 TD
• Passing Touchdowns: Scored 1.50 TD. Allowed 1.70 TD
• Total 1st Downs: Picked up 21.60. Allowed 19.20
• Total Turnovers: Committed 1.50. Committed by opponents 1.80
• Total Penalties: Committed 5.70. Committed by opponents 3.20
• Penalty Yards: Lost 56.10 Yds. Gained 25.80 Yds

Team News

NFL Standings Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Division Conference League

AFC East	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Bills	2	0	0	1.000	71	50	21	1-0-0	1-0-0	1-0-0	2-0-0	2-0-0	2W
Patriots	1	1	0	0.500	46	47	-1	0-1-0	1-0-0	1-0-0	1-1-0	1-1-0	1W
Jets	0	2	0	0.000	42	64	-22	0-2-0	0-0-0	0-1-0	0-2-0	0-2-0	2L
Dolphins	0	2	0	0.000	35	66	-31	0-1-0	0-1-0	0-1-0	0-2-0	0-2-0	2L

AFC North	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Bengals	2	0	0	1.000	48	43	5	1-0-0	1-0-0	1-0-0	2-0-0	2-0-0	2W
Ravens	1	1	0	0.500	81	58	23	1-0-0	0-1-0	1-0-0	1-1-0	1-1-0	1W
Steelers	1	1	0	0.500	51	63	-12	0-1-0	1-0-0	0-0-0	1-0-0	1-1-0	1L
Browns	0	2	0	0.000	33	58	-25	0-1-0	0-1-0	0-2-0	0-2-0	0-2-0	2L

AFC South	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Colts	2	0	0	1.000	62	36	26	2-0-0	0-0-0	0-0-0	2-0-0	2-0-0	2W
Jaguars	1	1	0	0.500	53	41	12	1-0-0	0-1-0	0-0-0	0-1-0	1-1-0	1L
Texans	0	2	0	0.000	28	34	-6	0-1-0	0-1-0	0-0-0	0-0-0	0-2-0	2L
Titans	0	2	0	0.000	31	53	-22	0-1-0	0-1-0	0-0-0	0-1-0	0-2-0	2L

AFC West	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Chargers	2	0	0	1.000	47	30	17	1-0-0	1-0-0	2-0-0	2-0-0	2-0-0	2W
Raiders	1	1	0	0.500	29	33	-4	0-1-0	1-0-0	0-1-0	1-1-0	1-1-0	1L
Broncos	1	1	0	0.500	48	41	7	1-0-0	0-1-0	0-0-0	1-1-0	1-1-0	1L
Chiefs	0	2	0	0.000	38	47	-9	0-1-0	0-1-0	0-1-0	0-1-0	0-2-0	2L

NFC East	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Eagles	2	0	0	1.000	44	37	7	1-0-0	1-0-0	1-0-0	1-0-0	2-0-0	2W
Commanders	1	1	0	0.500	39	33	6	1-0-0	0-1-0	1-0-0	1-1-0	1-1-0	1L
Cowboys	1	1	0	0.500	60	61	-1	1-0-0	0-1-0	1-1-0	1-1-0	1-1-0	1W
Giants	0	2	0	0.000	43	61	-18	0-0-0	0-2-0	0-2-0	0-2-0	0-2-0	2L

NFC North	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Packers	2	0	0	1.000	54	31	23	2-0-0	0-0-0	1-0-0	2-0-0	2-0-0	2W
Vikings	1	1	0	0.500	33	46	-13	0-1-0	1-0-0	1-0-0	1-1-0	1-1-0	1L
Lions	1	1	0	0.500	65	48	17	1-0-0	0-1-0	1-1-0	1-1-0	1-1-0	1W
Bears	0	2	0	0.000	45	79	-34	0-1-0	0-1-0	0-2-0	0-2-0	0-2-0	2L

NFC South	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Buccaneers	2	0	0	1.000	43	39	4	0-0-0	2-0-0	1-0-0	1-0-0	2-0-0	2W
Falcons	1	1	0	0.500	42	29	13	0-1-0	1-0-0	0-1-0	1-1-0	1-1-0	1W
Saints	0	2	0	0.000	34	46	-12	0-2-0	0-0-0	0-0-0	0-2-0	0-2-0	2L
Panthers	0	2	0	0.000	32	53	-21	0-0-0	0-2-0	0-0-0	0-1-0	0-2-0	2L

NFC West	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
49ers	2	0	0	1.000	43	34	9	0-0-0	2-0-0	1-0-0	2-0-0	2-0-0	2W
Cardinals	2	0	0	1.000	47	35	12	1-0-0	1-0-0	0-0-0	2-0-0	2-0-0	2W
Rams	2	0	0	1.000	47	28	19	1-0-0	1-0-0	0-0-0	0-0-0	2-0-0	2W
Seahawks	1	1	0	0.500	44	34	10	0-1-0	1-0-0	0-1-0	0-1-0	1-1-0	1W

AFC Conference	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Colts	2	0	0	1.000	62	36	26	2-0-0	0-0-0	0-0-0	2-0-0	2-0-0	2W
Bills	2	0	0	1.000	71	50	21	1-0-0	1-0-0	1-0-0	2-0-0	2-0-0	2W
Chargers	2	0	0	1.000	47	30	17	1-0-0	1-0-0	2-0-0	2-0-0	2-0-0	2W
Bengals	2	0	0	1.000	48	43	5	1-0-0	1-0-0	1-0-0	2-0-0	2-0-0	2W
Raiders	1	1	0	0.500	29	33	-4	0-1-0	1-0-0	0-1-0	1-1-0	1-1-0	1L
Ravens	1	1	0	0.500	81	58	23	1-0-0	0-1-0	1-0-0	1-1-0	1-1-0	1W
Patriots	1	1	0	0.500	46	47	-1	0-1-0	1-0-0	1-0-0	1-1-0	1-1-0	1W
Steelers	1	1	0	0.500	51	63	-12	0-1-0	1-0-0	0-0-0	1-0-0	1-1-0	1L
Broncos	1	1	0	0.500	48	41	7	1-0-0	0-1-0	0-0-0	1-1-0	1-1-0	1L
Jaguars	1	1	0	0.500	53	41	12	1-0-0	0-1-0	0-0-0	0-1-0	1-1-0	1L
Titans	0	2	0	0.000	31	53	-22	0-1-0	0-1-0	0-0-0	0-1-0	0-2-0	2L
Dolphins	0	2	0	0.000	35	66	-31	0-1-0	0-1-0	0-1-0	0-2-0	0-2-0	2L
Chiefs	0	2	0	0.000	38	47	-9	0-1-0	0-1-0	0-1-0	0-1-0	0-2-0	2L
Jets	0	2	0	0.000	42	64	-22	0-2-0	0-0-0	0-1-0	0-2-0	0-2-0	2L
Browns	0	2	0	0.000	33	58	-25	0-1-0	0-1-0	0-2-0	0-2-0	0-2-0	2L
Texans	0	2	0	0.000	28	34	-6	0-1-0	0-1-0	0-0-0	0-0-0	0-2-0	2L

NFC Conference	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Packers	2	0	0	1.000	54	31	23	2-0-0	0-0-0	1-0-0	2-0-0	2-0-0	2W
Eagles	2	0	0	1.000	44	37	7	1-0-0	1-0-0	1-0-0	1-0-0	2-0-0	2W
Buccaneers	2	0	0	1.000	43	39	4	0-0-0	2-0-0	1-0-0	1-0-0	2-0-0	2W
49ers	2	0	0	1.000	43	34	9	0-0-0	2-0-0	1-0-0	2-0-0	2-0-0	2W
Cardinals	2	0	0	1.000	47	35	12	1-0-0	1-0-0	0-0-0	2-0-0	2-0-0	2W
Rams	2	0	0	1.000	47	28	19	1-0-0	1-0-0	0-0-0	0-0-0	2-0-0	2W
Falcons	1	1	0	0.500	42	29	13	0-1-0	1-0-0	0-1-0	1-1-0	1-1-0	1W
Commanders	1	1	0	0.500	39	33	6	1-0-0	0-1-0	1-0-0	1-1-0	1-1-0	1L
Vikings	1	1	0	0.500	33	46	-13	0-1-0	1-0-0	1-0-0	1-1-0	1-1-0	1L
Cowboys	1	1	0	0.500	60	61	-1	1-0-0	0-1-0	1-1-0	1-1-0	1-1-0	1W
Lions	1	1	0	0.500	65	48	17	1-0-0	0-1-0	1-1-0	1-1-0	1-1-0	1W
Seahawks	1	1	0	0.500	44	34	10	0-1-0	1-0-0	0-1-0	0-1-0	1-1-0	1W
Panthers	0	2	0	0.000	32	53	-21	0-0-0	0-2-0	0-0-0	0-1-0	0-2-0	2L
Bears	0	2	0	0.000	45	79	-34	0-1-0	0-1-0	0-2-0	0-2-0	0-2-0	2L
Saints	0	2	0	0.000	34	46	-12	0-2-0	0-0-0	0-0-0	0-2-0	0-2-0	2L
Giants	0	2	0	0.000	43	61	-18	0-0-0	0-2-0	0-2-0	0-2-0	0-2-0	2L

NFL Team	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Cardinals	2	0	0	1.000	47	35	12	1-0-0	1-0-0	0-0-0	2-0-0	2-0-0	2W
Bills	2	0	0	1.000	71	50	21	1-0-0	1-0-0	1-0-0	2-0-0	2-0-0	2W
Bengals	2	0	0	1.000	48	43	5	1-0-0	1-0-0	1-0-0	2-0-0	2-0-0	2W
Packers	2	0	0	1.000	54	31	23	2-0-0	0-0-0	1-0-0	2-0-0	2-0-0	2W
Colts	2	0	0	1.000	62	36	26	2-0-0	0-0-0	0-0-0	2-0-0	2-0-0	2W
Chargers	2	0	0	1.000	47	30	17	1-0-0	1-0-0	2-0-0	2-0-0	2-0-0	2W
Rams	2	0	0	1.000	47	28	19	1-0-0	1-0-0	0-0-0	0-0-0	2-0-0	2W
Eagles	2	0	0	1.000	44	37	7	1-0-0	1-0-0	1-0-0	1-0-0	2-0-0	2W
49ers	2	0	0	1.000	43	34	9	0-0-0	2-0-0	1-0-0	2-0-0	2-0-0	2W
Buccaneers	2	0	0	1.000	43	39	4	0-0-0	2-0-0	1-0-0	1-0-0	2-0-0	2W
Falcons	1	1	0	0.500	42	29	13	0-1-0	1-0-0	0-1-0	1-1-0	1-1-0	1W
Ravens	1	1	0	0.500	81	58	23	1-0-0	0-1-0	1-0-0	1-1-0	1-1-0	1W
Cowboys	1	1	0	0.500	60	61	-1	1-0-0	0-1-0	1-1-0	1-1-0	1-1-0	1W
Broncos	1	1	0	0.500	48	41	7	1-0-0	0-1-0	0-0-0	1-1-0	1-1-0	1L
Lions	1	1	0	0.500	65	48	17	1-0-0	0-1-0	1-1-0	1-1-0	1-1-0	1W
Jaguars	1	1	0	0.500	53	41	12	1-0-0	0-1-0	0-0-0	0-1-0	1-1-0	1L
Raiders	1	1	0	0.500	29	33	-4	0-1-0	1-0-0	0-1-0	1-1-0	1-1-0	1L
Vikings	1	1	0	0.500	33	46	-13	0-1-0	1-0-0	1-0-0	1-1-0	1-1-0	1L
Patriots	1	1	0	0.500	46	47	-1	0-1-0	1-0-0	1-0-0	1-1-0	1-1-0	1W
Steelers	1	1	0	0.500	51	63	-12	0-1-0	1-0-0	0-0-0	1-0-0	1-1-0	1L
Seahawks	1	1	0	0.500	44	34	10	0-1-0	1-0-0	0-1-0	0-1-0	1-1-0	1W
Commanders	1	1	0	0.500	39	33	6	1-0-0	0-1-0	1-0-0	1-1-0	1-1-0	1L
Panthers	0	2	0	0.000	32	53	-21	0-0-0	0-2-0	0-0-0	0-1-0	0-2-0	2L
Bears	0	2	0	0.000	45	79	-34	0-1-0	0-1-0	0-2-0	0-2-0	0-2-0	2L
Browns	0	2	0	0.000	33	58	-25	0-1-0	0-1-0	0-2-0	0-2-0	0-2-0	2L
Texans	0	2	0	0.000	28	34	-6	0-1-0	0-1-0	0-0-0	0-0-0	0-2-0	2L
Chiefs	0	2	0	0.000	38	47	-9	0-1-0	0-1-0	0-1-0	0-1-0	0-2-0	2L
Dolphins	0	2	0	0.000	35	66	-31	0-1-0	0-1-0	0-1-0	0-2-0	0-2-0	2L
Saints	0	2	0	0.000	34	46	-12	0-2-0	0-0-0	0-0-0	0-2-0	0-2-0	2L
Giants	0	2	0	0.000	43	61	-18	0-0-0	0-2-0	0-2-0	0-2-0	0-2-0	2L
Jets	0	2	0	0.000	42	64	-22	0-2-0	0-0-0	0-1-0	0-2-0	0-2-0	2L
Titans	0	2	0	0.000	31	53	-22	0-1-0	0-1-0	0-0-0	0-1-0	0-2-0	2L