Cardinals vs Seahawks Prediction, Picks & Odds | 09 Nov 2025

NFL Betting Preview: Cardinals vs Seahawks

The Arizona Cardinals go up against the Seattle Seahawks at Lumen Field, with kickoff scheduled for 16:05 on Sunday, November 9. Our betting preview features expert NFL predictions, picks, updated betting odds, head-to-head stats and the latest team news, including injuries.

The Seahawks should be taken against the spread at -6.5 with our prediction being for the favorites to achieve a comfortable margin of victory over the Cardinals. Back them at the odds of -115 that are available.

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Arizona Cardinals got the win in their previous game. A 27-17 triumph occurred on the road at AT&T Stadium when playing Dallas Cowboys. The Cardinals moved the ball for 340 yards, breaking down to 221 passing and 119 rushing yards. They moved the chains 23 times and scored 3 touchdowns, with 2 through the air and one on the ground.

Seattle Seahawks have triumphed in their last three games. The latest of these was on the road where Washington Commanders were beaten 38-14 at Northwest Stadium. The Seahawks moved the ball for 418 yards, including 330 passing and 88 rushing yards. They produced 21 first downs and scored 5 touchdowns, with 4 through the air and one on the ground.

Head-to-Head Statistics

The Seahawks won the most recent matchup between these teams. A 23-20 victory was registered against the Cardinals at State Farm Stadium. It’s been nine Seahawks wins in the past 10 games between these teams.

Quarterbacks

Jacoby Brissett

235.5 Passing Yards

Over -112

Under -112

Sam Darnold

257.5 Passing Yards

Over -112

Under -112

Cardinals vs Seahawks Prediction & Picks

Our Cardinals vs Seahawks betting guide delivers expert insight, including a main match pick, scoreline advice, standout player props and bet builder recommendations. Dive into each section below for more.

Game Prediction

We’re excited to see the market leaders at -6.5 on the spread in this NFL matchup. We think it’s an awesome number for the Seahawks to cover at odds of -115.

We use the latest team news and injury updates to help shape the best possible NFL picks. You’ll also notice we take a stats-led approach by factoring in the key numbers that truly make a difference.

Key Cardinals vs Seahawks stats:

• The -6.5 line has been covered by Seahawks in 3 consecutive games.
• The -6.5 line has been covered by Seahawks in 5 of their last 8 games this season.
• The -6.5 line has been covered by Seahawks in 7 of their last 10 games against Cardinals.

Seahawks -6.5 Probability

When looking at the latest odds, our pick has a 53.5% chance of delivering a return. In the opinion of our analysts, there’s actually a probability of success closer to 60%. It’s why we think it’s worth placing this wager.

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Our Game Prediction

Seahawks -6.5 @ -115 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (22:26, 07 November 2025). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Sam Darnold Over 259.5 Passing Yards -114

The odds for Sam Darnold (Seahawks) to surpass 259.5 passing yards are -114. We're confident in him covering the QB Passing Yards line and hitting our Over bet.

Latest Sam Darnold Player Prop Odds

Touchdown

Anytime

+1100

First

+4500

Passing Yards

Over 257.5

-112

Under 257.5

-112

Rushing Yards

Over 5.5

-108

Under 5.5

-118

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Jacoby Brissett Over 14.5 Rushing Yards -108

Jacoby Brissett (Cardinals) is available at -108 to surpass 14.5 rushing yards. The line for him on the Overs is highly appealing, with Player Rushing Yards bettors able to get plenty of juice.

Latest Jacoby Brissett Player Prop Odds

Touchdown

Anytime

+750

First

+3300

Passing Yards

Over 235.5

-112

Under 235.5

-112

Rushing Yards

Over 14.5

-108

Under 14.5

-118

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Cardinals 20 - 30 Seahawks

There are stacks of correct score lines on offer and we’re looking at the Seahawks to achieve a winning scoreline of 30-20 where a huge potential return is on the cards.

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Cardinals vs Seahawks Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The sportsbooks’ betting odds have Seattle Seahawks as -120 favorites for this game, implying that they are 55% likely to win. Arizona Cardinals are trading at bigger odds than their opponents and they can be backed at -100.

The current spread is 1.5 and total points is 45.5. A Total bet is always available and can often provide value selections. Those that want to back Under 45.5 can find odds of -110 available.

Whether you are wagering pre-game or in-game on the National Football League, the best betting apps offer a wide range of game lines and team props. The selections are practically endless and it’s great to have so many different options.

Moneyline

Cardinals

-100

Seahawks

-120

Point Spread

Cardinals +1.5

-110

Seahawks -1.5

-110

Total Points

Under 45.5

-110

Over 45.5

-110

Jaxon Smith-Njigba is available at +105 when it comes to Anytime Touchdown Scorer. The favorite is now priced at odds of +500 to score the first TD.

Touchdown

Jaxon Smith-Njigba (Seahawks)

First TD

+500

Anytime TD

+105

Zach Charbonnet (Seahawks)

First TD

+800

Anytime TD

+145

Kenneth Walker III (Seahawks)

First TD

+900

Anytime TD

+180

Trey McBride (Cardinals)

First TD

+950

Anytime TD

+155

Rashid Shaheed (Seahawks)

First TD

+1000

Anytime TD

+210

Marvin Harrison Jr. (Cardinals)

First TD

+1000

Anytime TD

+190

AJ Barner (Seahawks)

First TD

+1100

Anytime TD

+240

Elijah Arroyo (Seahawks)

First TD

+1300

Anytime TD

+300

Cooper Kupp (Seahawks)

First TD

+1300

Anytime TD

+320

Tory Horton (Seahawks)

First TD

+1400

Anytime TD

+240

Bam Knight (Cardinals)

First TD

+1400

Anytime TD

+290

Emari Demercado (Cardinals)

First TD

+1600

Anytime TD

+320

Michael Wilson (Cardinals)

First TD

+2000

Anytime TD

+430

Jacoby Brissett (Cardinals)

First TD

+3300

Anytime TD

+750

Sam Darnold (Seahawks)

First TD

+4500

Anytime TD

+1100

Zay Jones (Cardinals)

First TD

+4500

Anytime TD

+1000

Cody White (Seahawks)

First TD

+6500

Anytime TD

+1100

Elijah Higgins (Cardinals)

First TD

+7000

Anytime TD

+950

Greg Dortch (Cardinals)

First TD

+7500

Anytime TD

+1200

Nick Kallerup (Seahawks)

First TD

+8000

Anytime TD

+1900

Josiah Deguara (Cardinals)

First TD

+10000

Anytime TD

+3500

Robbie Ouzts (Seahawks)

First TD

+10000

Anytime TD

+3000

Xavier Weaver (Cardinals)

First TD

+10000

Anytime TD

+3300

George Holani (Seahawks)

First TD

+10000

Anytime TD

+3000

Simi Fehoko (Cardinals)

First TD

+10000

Anytime TD

+4000

Jake Bobo (Seahawks)

First TD

+10000

Anytime TD

+3000

Ricky White III (Seahawks)

First TD

+10000

Anytime TD

+2200

Michael Carter (Cardinals)

First TD

+10000

Anytime TD

+2000

Dareke Young (Seahawks)

First TD

+10000

Anytime TD

+3000

Receiving Yards

Jaxon Smith-Njigba (Seahawks)

Over 95.5

-112

Under 95.5

-112

Trey McBride (Cardinals)

Over 62.5

-112

Under 62.5

-112

Marvin Harrison Jr. (Cardinals)

Over 55.5

-112

Under 55.5

-112

Rashid Shaheed (Seahawks)

Over 32.5

-112

Under 32.5

-112

Michael Wilson (Cardinals)

Over 30.5

-112

Under 30.5

-112

AJ Barner (Seahawks)

Over 27.5

-112

Under 27.5

-112

Cooper Kupp (Seahawks)

Over 23.5

-112

Under 23.5

-112

Elijah Arroyo (Seahawks)

Over 19.5

-112

Under 19.5

-112

Zay Jones (Cardinals)

Over 13.5

-112

Under 13.5

-112

Bam Knight (Cardinals)

Over 11.5

-112

Under 11.5

-112

Emari Demercado (Cardinals)

Over 8.5

-112

Under 8.5

-112

Zach Charbonnet (Seahawks)

Over 7.5

-108

Under 7.5

-118

Kenneth Walker III (Seahawks)

Over 6.5

-112

Under 6.5

-112

Rushing Yards

Kenneth Walker III (Seahawks)

Over 54.5

-112

Under 54.5

-112

Zach Charbonnet (Seahawks)

Over 38.5

-112

Under 38.5

-112

Emari Demercado (Cardinals)

Over 35.5

-112

Under 35.5

-112

Bam Knight (Cardinals)

Over 28.5

-112

Under 28.5

-112

Jacoby Brissett (Cardinals)

Over 14.5

-108

Under 14.5

-118

Sam Darnold (Seahawks)

Over 5.5

-108

Under 5.5

-118

Passing Yards

Sam Darnold (Seahawks)

Over 257.5

-112

Under 257.5

-112

Jacoby Brissett (Cardinals)

Over 235.5

-112

Under 235.5

-112

It’s good to consider all wagering options when it comes to NFL and micro betting can be an exciting way to get involved in the action. When everything goes in-game, consider whether a player will make or miss a field goal.

Seahawks Hold Advantage in Recent Head-to-Head Meetings at Lumen Field

The Seahawks own a 3-7 mark in their past 10 home games, averaging 22.60 points scored and 24.30 points allowed.

The Cardinals own a 3-7 mark in their past 10 road games, averaging 19.70 points scored and 22.60 points allowed.

The previous meeting at Lumen Field saw the Seahawks defeat the Cardinals 16-6. In the last 6 head-to-head games at Lumen Field, the Seahawks have notched four victories, with the Cardinals posting two.

Last 10 Games		W-L	P	PF	PA	O44.5	U44.5
Seahawks Home Stats		3-7	46.90	22.60	24.30	6	4
Cardinals Away Stats		3-7	42.30	19.70	22.60	5	5

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O44.5 = Games Over 44.5 Points
• U44.5 = Games Under 44.5 Points

Latest regular season and playoff games stats.

Arizona Cardinals Stats

Seattle Seahawks Stats

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 games on the road

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 home games

Point Spread

• +6.5 Betting Line: Have covered the spread in the last 10 games
• +6.5 Betting Line on the Road: Have covered the spread in 8 of the last 10 games on the road

Point Spread

• -6.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -6.5 Betting Line at Home: Have covered the spread in 3 of the last 10 home games

Total Points

• Game Totals: An average of 44.40 pts in the previous 10 games
• Game Totals on the Road: An average of 42.30 pts in the previous 10 games on the road
• Over 44.5: Covered in 4 of the previous 10 games
• Over 44.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 23.60 pts and allowed 20.80 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 19.70 pts and allowed 22.60 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 44.50 pts in the previous 10 games
• Game Totals at Home: An average of 46.90 pts in the previous 10 home games
• Over 44.5: Covered in 6 of the previous 10 games
• Over 44.5 at Home: Covered in 6 of the previous 10 home games
• Team Totals: Have scored an average of 26.70 pts and allowed 17.80 pts in the last 10 games
• Team Totals at Home: Have scored an average of 22.60 pts and allowed 24.30 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 330.10 Yds. Allowed 337.60 Yds
• Rushing Yards: Gained 115.60 Yds. Allowed 103.50 Yds
• Passing Yards: Gained 214.50 Yds. Allowed 234.10 Yds
• Total Touchdowns: Scored 2.60 TD. Allowed 2.20 TD
• Rushing Touchdowns: Scored 0.80 TD. Allowed 0.90 TD
• Passing Touchdowns: Scored 1.70 TD. Allowed 1.10 TD
• Total 1st Downs: Picked up 20.60. Allowed 21.00
• Total Turnovers: Committed 1.00. Committed by opponents 1.30
• Total Penalties: Committed 6.60. Committed by opponents 7.80
• Penalty Yards: Lost 47.00 Yds. Gained 67.00 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 347.00 Yds. Allowed 301.30 Yds
• Rushing Yards: Gained 107.90 Yds. Allowed 87.40 Yds
• Passing Yards: Gained 239.10 Yds. Allowed 213.90 Yds
• Total Touchdowns: Scored 3.10 TD. Allowed 1.80 TD
• Rushing Touchdowns: Scored 0.90 TD. Allowed 0.40 TD
• Passing Touchdowns: Scored 2.00 TD. Allowed 1.30 TD
• Total 1st Downs: Picked up 18.60. Allowed 18.60
• Total Turnovers: Committed 1.40. Committed by opponents 1.20
• Total Penalties: Committed 5.70. Committed by opponents 6.70
• Penalty Yards: Lost 48.10 Yds. Gained 53.70 Yds

Last 10 Games on the Road

• Total Yards: Gained 344.70 Yds. Allowed 332.70 Yds
• Rushing Yards: Gained 113.50 Yds. Allowed 117.00 Yds
• Passing Yards: Gained 231.20 Yds. Allowed 215.70 Yds
• Total Touchdowns: Scored 1.80 TD. Allowed 2.50 TD
• Rushing Touchdowns: Scored 0.50 TD. Allowed 0.90 TD
• Passing Touchdowns: Scored 1.30 TD. Allowed 1.50 TD
• Total 1st Downs: Picked up 20.70. Allowed 20.40
• Total Turnovers: Committed 1.10. Committed by opponents 0.80
• Total Penalties: Committed 7.30. Committed by opponents 6.00
• Penalty Yards: Lost 57.90 Yds. Gained 52.50 Yds

Last 10 Home Games

• Total Yards: Gained 319.50 Yds. Allowed 360.70 Yds
• Rushing Yards: Gained 80.60 Yds. Allowed 104.00 Yds
• Passing Yards: Gained 238.90 Yds. Allowed 256.70 Yds
• Total Touchdowns: Scored 2.70 TD. Allowed 2.60 TD
• Rushing Touchdowns: Scored 0.90 TD. Allowed 0.60 TD
• Passing Touchdowns: Scored 1.60 TD. Allowed 1.80 TD
• Total 1st Downs: Picked up 19.50. Allowed 21.50
• Total Turnovers: Committed 2.20. Committed by opponents 0.80
• Total Penalties: Committed 8.40. Committed by opponents 7.70
• Penalty Yards: Lost 73.10 Yds. Gained 63.90 Yds

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