Cardinals vs Buccaneers Prediction, Picks & Odds | 30 Nov 2025

NFL Betting Preview: Cardinals vs Buccaneers

The Arizona Cardinals go up against the Tampa Bay Buccaneers at Raymond James Stadium, with kickoff scheduled for 13:00 on Sunday, November 30.

We’re expecting Over 45.5 points to be scored by the Buccaneers and the Cardinals combined. There’s an attractive -105 for our prediction and we’re anticipating that the scoreboard will tick over.

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Arizona Cardinals have suffered three straight defeats, recently being beaten at home by Jacksonville Jaguars 27-24 (OT) at State Farm Stadium. The Cardinals put up 326 total yards, made up of 271 through the air and 55 on the ground. The offense managed 25 first downs and found the end zone 3 times.

Tampa Bay Buccaneers lost on the road in their last game, making it three straight defeats. Los Angeles Rams won 34-7 at SoFi Stadium. The Buccaneers moved the ball for 193 yards, with 70 through the air and 123 on the ground. The offense scored one passing TD and managed 14 first downs.

Head-to-Head Statistics

The Bucs triumphed 19-16 (OT) when they last played the Cardinals. This head-to-head was played at State Farm Stadium.

Quarterbacks

Jacoby Brissett

257.5 Passing Yards

Over -112

Under -112

Baker Mayfield

229.5 Passing Yards

Over -112

Under -112

Cardinals vs Buccaneers Prediction & Picks

We bring you the complete Cardinals vs Buccaneers betting insight, including our top match prediction, correct score forecast, player prop advice and a ready-made bet builder.

Game Prediction

There could be plenty of points being racked up during this NFL battle, with our pick being Over 45.5 points in total. Odds of -105 look worth taking for this outcome.

Tracking injury updates is a big part of our analysis and team news plays a major role in shaping our NFL predictions. We combine this with recent form and the most important stats to get a complete picture.

Key Cardinals vs Buccaneers stats:

• The 45.5 line has been covered in 4 of the last 5 Cardinals games.
• The 45.5 line has been covered in 6 of the last 10 Cardinals games.
• The 45.5 line has been covered in the last 3 Cardinals games.
• The 45.5 line has been covered in the last 4 Buccaneers games at home.
• The 45.5 line has been covered in 7 of the last 10 Buccaneers games at home.
• The 45.5 line has been covered in 6 of the last 11 Buccaneers games this season.

Over 45.5 Probability

According to the latest betting odds, our pick has a 51.3% chance of winning. After careful examination, our analysts calculate this probability to be closer to 60%. That means we are regarding it as a value wager.

There’s a chance to secure larger odds when you bet on the Totals. The sportsbooks allow you to move the line for an Over pick until you’re happy with the potential return.

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Our Game Prediction

Over 45.5 Points @ -105 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (19:25, 28 November 2025). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Jacoby Brissett Over 270.5 Passing Yards -114

Jacoby Brissett (Cardinals) can be backed at -114 to record more than 270.5 passing yards. There’s an opportunity to place a QB Passing Yards bet, with him capable of covering an appealing line.

Latest Jacoby Brissett Player Prop Odds

Touchdown

Anytime

+700

First

+3300

Passing Yards

Over 257.5

-112

Under 257.5

-112

Rushing Yards

Over 12.5

-112

Under 12.5

-112

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Bucky Irving Anytime TD +115

Bucky Irving (Bucs) is available at +115 to reach the goal line. We believe this is the best of the player props, with attractive odds available when it comes to betting him to score a touchdown at any time.

Latest Bucky Irving Player Prop Odds

Touchdown

Anytime

+180

First

+850

Receiving Yards

Over 13.5

-112

Under 13.5

-112

Rushing Yards

Over 40.5

-112

Under 40.5

-112

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Cardinals 27 - 23 Buccaneers

There’s every chance that this is going to be a close battle and we’ll have a play on the Cardinals enjoying a 27-23 winning scoreline. Hopefully this can go close.

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Cardinals vs Buccaneers Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Tampa Bay Buccaneers are -175 favorites and that means a 64% chance of winning this game according to the Moneyline betting odds with the sportsbooks. For those wanting to oppose the market leader, you can get +145 about Arizona Cardinals.

3.5 is the spread and 48.5 is the total points line. There are many ways to bet on the NFL including the Totals. If you fancy Over 48.5, this outcome can be backed at -110.

There’s no shortage of betting opportunities when it comes to the National Football League. The top sportsbooks offer a wide variety of game lines and team props for each matchup, so be sure to explore both the pre-game and in-game markets before making your pick.

Moneyline

Cardinals

+145

Buccaneers

-175

Point Spread

Cardinals +3.5

-110

Buccaneers -3.5

-110

Total Points

Under 48.5

-110

Over 48.5

-110

There’s the chance to back Trey McBride at +700 to be the First Touchdown Scorer. He’s the favorite and available at similar odds to record the last TD instead.

Touchdown

Trey McBride (Cardinals)

First TD

+700

Anytime TD

+135

Emeka Egbuka (Buccaneers)

First TD

+700

Anytime TD

+150

Bucky Irving (Buccaneers)

First TD

+850

Anytime TD

+180

Cade Otton (Buccaneers)

First TD

+1000

Anytime TD

+220

Bam Knight (Cardinals)

First TD

+1100

Anytime TD

+230

Marvin Harrison Jr. (Cardinals)

First TD

+1100

Anytime TD

+220

Michael Wilson (Cardinals)

First TD

+1100

Anytime TD

+230

Chris Godwin (Buccaneers)

First TD

+1100

Anytime TD

+240

Sean Tucker (Buccaneers)

First TD

+1200

Anytime TD

+240

Rachaad White (Buccaneers)

First TD

+1500

Anytime TD

+310

Tez Johnson (Buccaneers)

First TD

+1800

Anytime TD

+390

Michael Carter (Cardinals)

First TD

+2000

Anytime TD

+340

Sterling Shepard (Buccaneers)

First TD

+2200

Anytime TD

+550

Greg Dortch (Cardinals)

First TD

+2500

Anytime TD

+600

Jacoby Brissett (Cardinals)

First TD

+3300

Anytime TD

+700

Baker Mayfield (Buccaneers)

First TD

+4000

Anytime TD

+1100

Elijah Higgins (Cardinals)

First TD

+5000

Anytime TD

+800

Owen Wright (Buccaneers)

First TD

+8000

Anytime TD

+1900

Ryan Miller (Buccaneers)

First TD

+8000

Anytime TD

+1100

Payne Durham (Buccaneers)

First TD

+8000

Anytime TD

+1100

Jermar Jefferson (Cardinals)

First TD

+10000

Anytime TD

+2500

Xavier Weaver (Cardinals)

First TD

+10000

Anytime TD

+1600

Josiah Deguara (Cardinals)

First TD

+10000

Anytime TD

+2200

Kameron Johnson (Buccaneers)

First TD

+10000

Anytime TD

+1800

Andre Baccellia (Cardinals)

First TD

+10000

Anytime TD

+3000

Devin Culp (Buccaneers)

First TD

+10000

Anytime TD

+2700

Pharaoh Brown (Cardinals)

First TD

+10000

Anytime TD

+3000

Receiving Yards

Trey McBride (Cardinals)

Over 68.5

-112

Under 68.5

-112

Emeka Egbuka (Buccaneers)

Over 60.5

-112

Under 60.5

-112

Michael Wilson (Cardinals)

Over 54.5

-112

Under 54.5

-112

Marvin Harrison Jr. (Cardinals)

Over 52.5

-112

Under 52.5

-112

Cade Otton (Buccaneers)

Over 35.5

-112

Under 35.5

-112

Chris Godwin (Buccaneers)

Over 30.5

-112

Under 30.5

-112

Tez Johnson (Buccaneers)

Over 25.5

-112

Under 25.5

-112

Greg Dortch (Cardinals)

Over 16.5

-112

Under 16.5

-112

Sterling Shepard (Buccaneers)

Over 15.5

-112

Under 15.5

-112

Bucky Irving (Buccaneers)

Over 13.5

-112

Under 13.5

-112

Bam Knight (Cardinals)

Over 12.5

-112

Under 12.5

-112

Rachaad White (Buccaneers)

Over 10.5

-112

Under 10.5

-112

Rushing Yards

Bucky Irving (Buccaneers)

Over 40.5

-112

Under 40.5

-112

Bam Knight (Cardinals)

Over 35.5

-112

Under 35.5

-112

Sean Tucker (Buccaneers)

Over 30.5

-112

Under 30.5

-112

Michael Carter (Cardinals)

Over 18.5

-112

Under 18.5

-112

Rachaad White (Buccaneers)

Over 14.5

-112

Under 14.5

-112

Jacoby Brissett (Cardinals)

Over 12.5

-112

Under 12.5

-112

Baker Mayfield (Buccaneers)

Over 8.5

-112

Under 8.5

-112

Passing Yards

Jacoby Brissett (Cardinals)

Over 257.5

-112

Under 257.5

-112

Baker Mayfield (Buccaneers)

Over 229.5

-112

Under 229.5

-112

There are lots of exciting NFL micro betting lines that are created and they are available in-game. Among them are whether a field goal will be scored and you simply bet whether the player will make it or miss.

Bucs Hold Five Wins in Previous Ten at Home

The Bucs have gone 5-5 across their last 10 home games, putting up 27.60 points on average and giving up 22.80.

The Cardinals have three wins and seven losses in the last 10 road games, putting up 20.60 points on average and giving up 23.60.

The Bucs defeated the Cardinals 30-27 the last time they played at Raymond James Stadium.

Last 10 Games		W-L	P	PF	PA	O45.5	U45.5
Buccaneers Home Stats		5-5	50.40	27.60	22.80	7	3
Cardinals Away Stats		3-7	44.20	20.60	23.60	4	6

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O45.5 = Games Over 45.5 Points
• U45.5 = Games Under 45.5 Points

Latest regular season and playoff games stats.

Arizona Cardinals Stats

Tampa Bay Buccaneers Stats

Moneyline

• 2 wins and 8 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 home games

Point Spread

• +4.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +4.5 Betting Line on the Road: Have covered the spread in 7 of the last 10 games on the road

Point Spread

• -4.5 Betting Line: Have covered the spread in 2 of the last 10 games
• -4.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games

Total Points

• Game Totals: An average of 49.80 pts in the previous 10 games
• Game Totals on the Road: An average of 44.20 pts in the previous 10 games on the road
• Over 45.5: Covered in 6 of the previous 10 games
• Over 45.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 22.80 pts and allowed 27.00 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 20.60 pts and allowed 23.60 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 50.00 pts in the previous 10 games
• Game Totals at Home: An average of 50.40 pts in the previous 10 home games
• Over 45.5: Covered in 6 of the previous 10 games
• Over 45.5 at Home: Covered in 7 of the previous 10 home games
• Team Totals: Have scored an average of 23.60 pts and allowed 26.40 pts in the last 10 games
• Team Totals at Home: Have scored an average of 27.60 pts and allowed 22.80 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 338.50 Yds. Allowed 339.20 Yds
• Rushing Yards: Gained 96.60 Yds. Allowed 114.90 Yds
• Passing Yards: Gained 241.90 Yds. Allowed 224.30 Yds
• Total Touchdowns: Scored 2.60 TD. Allowed 3.00 TD
• Rushing Touchdowns: Scored 0.90 TD. Allowed 1.00 TD
• Passing Touchdowns: Scored 1.50 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 20.70. Allowed 21.50
• Total Turnovers: Committed 1.30. Committed by opponents 1.70
• Total Penalties: Committed 7.60. Committed by opponents 5.60
• Penalty Yards: Lost 56.90 Yds. Gained 54.50 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 325.50 Yds. Allowed 342.90 Yds
• Rushing Yards: Gained 112.20 Yds. Allowed 103.90 Yds
• Passing Yards: Gained 213.30 Yds. Allowed 239.00 Yds
• Total Touchdowns: Scored 2.60 TD. Allowed 3.20 TD
• Rushing Touchdowns: Scored 0.90 TD. Allowed 1.20 TD
• Passing Touchdowns: Scored 1.60 TD. Allowed 1.70 TD
• Total 1st Downs: Picked up 19.40. Allowed 18.20
• Total Turnovers: Committed 0.90. Committed by opponents 1.60
• Total Penalties: Committed 5.50. Committed by opponents 6.80
• Penalty Yards: Lost 41.70 Yds. Gained 54.60 Yds

Last 10 Games on the Road

• Total Yards: Gained 347.90 Yds. Allowed 326.20 Yds
• Rushing Yards: Gained 117.50 Yds. Allowed 118.90 Yds
• Passing Yards: Gained 230.40 Yds. Allowed 207.30 Yds
• Total Touchdowns: Scored 2.00 TD. Allowed 2.60 TD
• Rushing Touchdowns: Scored 0.60 TD. Allowed 1.10 TD
• Passing Touchdowns: Scored 1.40 TD. Allowed 1.20 TD
• Total 1st Downs: Picked up 21.20. Allowed 19.90
• Total Turnovers: Committed 1.00. Committed by opponents 1.00
• Total Penalties: Committed 6.50. Committed by opponents 5.80
• Penalty Yards: Lost 51.60 Yds. Gained 50.50 Yds

Last 10 Home Games

• Total Yards: Gained 374.30 Yds. Allowed 323.80 Yds
• Rushing Yards: Gained 128.90 Yds. Allowed 93.40 Yds
• Passing Yards: Gained 245.40 Yds. Allowed 230.40 Yds
• Total Touchdowns: Scored 3.10 TD. Allowed 2.40 TD
• Rushing Touchdowns: Scored 0.50 TD. Allowed 0.60 TD
• Passing Touchdowns: Scored 2.40 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 21.50. Allowed 18.40
• Total Turnovers: Committed 1.00. Committed by opponents 0.80
• Total Penalties: Committed 7.00. Committed by opponents 6.00
• Penalty Yards: Lost 54.80 Yds. Gained 54.70 Yds

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